MutT-related error avoidance mechanism for DNA synthesis

Genes to Cells

Volumn 1, Issue 2, 1996, Pages 139-145

  Sekiguchi, Mutsuo ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

8 OXODEOXYGUANOSINE TRIPHOSPHATE; 8 OXODGTPASE; 8-OXODEOXYGUANOSINE TRIPHOSPHATE; 8-OXODGTPASE; BACTERIAL PROTEIN; DEOXYGUANOSINE PHOSPHATE; ESCHERICHIA COLI PROTEIN; INORGANIC PYROPHOSPHATASE; MUTT PROTEIN, E COLI; PHOSPHATASE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE;

ESCHERICHIA COLI; GENETICS; HUMAN; METABOLISM; MUTAGENESIS; REVIEW;

BACTERIAL PROTEINS; DEOXYGUANINE NUCLEOTIDES; DNA REPAIR ENZYMES; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; HUMANS; MUTAGENESIS; PHOSPHORIC MONOESTER HYDROLASES; PYROPHOSPHATASES;

EID: 0030072561     PISSN: 13569597     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2443.1996.d01-232.x     Document Type: Article

References (9)

1. Akiyama, M., Horiuchi, T. & Sckiguchi, M. (1987) Molecular cloning and nucleotide sequence of the mutT mutator of Escherichia coli that causes A:T to C:G transversion. Mol. Gen. Genet. 206, 9-16.
2. Akiyama, M., Maki, H., Sckiguchi, M. & Horiuchi, T. (1989) A specific role of MutT protein: To prevent dG.dA mispairing in DNA replication. Proc. Natl Acad. Sci. USA 86, 3949-3952.
3. Au, K.G., Clark, S., Miller, J.H. & Modrich, P. (1989) Escherichia coli mutY gene encodes an adenine glycosylase active on G-A mispairs. Proc. Natl Acad. Sci. USA 86, 8877-8881.
4. Fraga, C.G., Shigenaga, M.K., Park, J.-W., Degan, P. & Ames, B.N. (1990) Oxidative damage to DNA during aging: 8-hydroxy-2′ -deoxyguanosine in rat organ DNA and urine. Proc. Natl Acad. Sci. USA 87, 4533-4537.
5. Furuichi, M., Yoshida, M.C., Oda, H., Tajiri, T., Nakabeppu, Y., Tsuzuki, T. & Sekiguchi, M. (1994) Genomic structure and chromosome location of the human mutT homologue gene MTH1 encoding 8-oxo-dGTPase for prevention of A:T to C:G transversion. Genomics 24, 485-490.
6. Hayakawa, H., Taketomi, A., Sakumi, K., Kuwano, M. & Sekiguchi, M. (1995) Generation and elimination of 8-oxo-7,8-dihydro-2′ -deoxyguanosine 5′ -triphosphate, a mutagenic substrate for DNA synthesis, in human cells. Biochem. 34, 89-95.
7. Horiuchi, T., Maki, H. & Sekiguchi, M. (1989) Mutators and fidelity of DNA replication. Bull. lust. Pasteur 87, 309-336.
8. Hruszkewycz A.M. & Bergtold, D.S. (1990) The 8-hydroxyguanine content of isolated mitochondria increases with lipid peroxidation. Mut. Res. 244, 123-128.
9. Kakuma, T., Nishida, J., Tsuzuki, T. & Sekiguchi, M. (1995) Mouse MTH1 protein with 8-oxo-7,8-dihydro-2′-deoxyguanosine 5′-triphosphatase activity that prevents transversion mutation. J. Biol. Chem. 270, 25942-25948.