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Volumn 36, Issue 6, 2002, Pages 1341-1348

A phylogenetic analysis identifies heterogeneity among hepatocellular carcinomas

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ALLELE; ARTICLE; CANCER MORTALITY; CHINESE; CHROMOSOME ANALYSIS; CLINICAL ARTICLE; CLUSTER ANALYSIS; CONTROLLED STUDY; FEMALE; GENE LOCUS; GENETIC HETEROGENEITY; GENOTYPE; HETEROZYGOSITY; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; MALE; MARKER GENE; MORBIDITY; PHYLOGENY; PRIORITY JOURNAL; RISK FACTOR;

EID: 0036896602     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/jhep.2002.37261     Document Type: Article
Times cited : (15)

References (58)
  • 1
    • 0033559933 scopus 로고    scopus 로고
    • Estimates of the worldwide incidence of 25 major cancers in 1990
    • Parkin DM, Pisani P, Ferlay J. Estimates of the worldwide incidence of 25 major cancers in 1990. Int J Cancer 1999;80:827-841.
    • (1999) Int J Cancer , vol.80 , pp. 827-841
    • Parkin, D.M.1    Pisani, P.2    Ferlay, J.3
  • 2
    • 0032843811 scopus 로고    scopus 로고
    • Estimates of the worldwide mortality from 25 major cancers in 1990
    • Pisani P, Parkin DM, Bray F, Ferlay J. Estimates of the worldwide mortality from 25 major cancers in 1990. Int J Cancer 1999;83:18-29.
    • (1999) Int J Cancer , vol.83 , pp. 18-29
    • Pisani, P.1    Parkin, D.M.2    Bray, F.3    Ferlay, J.4
  • 3
    • 0002586173 scopus 로고    scopus 로고
    • Liver cancer
    • Schottenfeld D, Fraumeni JF, Jr., eds. New York: Oxford University Press
    • London WF, McGlynn KA. Liver cancer. In: Schottenfeld D, Fraumeni JF, Jr., eds. Cancer Epidemiology and Prevention. New York: Oxford University Press, 1996;772-793.
    • (1996) Cancer Epidemiology and Prevention , pp. 772-793
    • London, W.F.1    McGlynn, K.A.2
  • 4
    • 0004035855 scopus 로고
    • Hepatitis B virus and hepatocellular carcinoma
    • Vyas GN, Dienstag JL, Hoofnagle JH, eds. New York, NY: Grune and Stratton, Inc.
    • Robinson WS, Miller RH, Klote L, Marion PL, Lee SC. Hepatitis B virus and hepatocellular carcinoma. In: Vyas GN, Dienstag JL, Hoofnagle JH, eds. Viral Hepatitis and Liver Disease. New York, NY: Grune and Stratton, Inc.; 1984:245-263.
    • (1984) Viral Hepatitis and Liver Disease , pp. 245-263
    • Robinson, W.S.1    Miller, R.H.2    Klote, L.3    Marion, P.L.4    Lee, S.C.5
  • 6
    • 0025828517 scopus 로고
    • Selective G to T mutations of p53 gene in hepatocellular carcinoma from southern Africa
    • Bressac B, Kew M, Wands J, Oxturk M. Selective G to T mutations of p53 gene in hepatocellular carcinoma from southern Africa. Nature 1991;350:429-431.
    • (1991) Nature , vol.350 , pp. 429-431
    • Bressac, B.1    Kew, M.2    Wands, J.3    Oxturk, M.4
  • 7
    • 0028957898 scopus 로고
    • Susceptibility to hepatocellular carcinoma is associated with genetic variation in the enzymatic detoxification of aflatoxin B1
    • McGlynn KA, Rosvold EA, Lustbader ED, Hu Y, Clapper ML, Zhou T, Wild CP, et al. Susceptibility to hepatocellular carcinoma is associated with genetic variation in the enzymatic detoxification of aflatoxin B1. Proc Natl Acad Sci U S A 1995;92:2384-2387.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 2384-2387
    • McGlynn, K.A.1    Rosvold, E.A.2    Lustbader, E.D.3    Hu, Y.4    Clapper, M.L.5    Zhou, T.6    Wild, C.P.7
  • 10
    • 0034083469 scopus 로고    scopus 로고
    • Mapping of a minimal deleted region in human hepatocellular carcinoma to 1p36.13-p36.23 and mutational analysis of the RIZ (PRDM2) gene localized to the region
    • Fang W, Piao Z, Simon D, Shue J-C, Huang S. Mapping of a minimal deleted region in human hepatocellular carcinoma to 1p36.13-p36.23 and mutational analysis of the RIZ (PRDM2) gene localized to the region. Genes Chromosomes Cancer 2000;28:269-275.
    • (2000) Genes Chromosomes Cancer , vol.28 , pp. 269-275
    • Fang, W.1    Piao, Z.2    Simon, D.3    Shue, J.-C.4    Huang, S.5
  • 11
    • 0033988602 scopus 로고    scopus 로고
    • Aberrant DNA methylation precedes loss of heterozygosity on chromosome 16 in chronic hepatitis and liver cirrhosis
    • Kanai Y, Ushijima S, Tsuda H, Sakamoto M, Hirohashi S. Aberrant DNA methylation precedes loss of heterozygosity on chromosome 16 in chronic hepatitis and liver cirrhosis. Cancer Lett 2000;148:73-80.
    • (2000) Cancer Lett , vol.148 , pp. 73-80
    • Kanai, Y.1    Ushijima, S.2    Tsuda, H.3    Sakamoto, M.4    Hirohashi, S.5
  • 12
    • 0032498316 scopus 로고    scopus 로고
    • Homozygous deletions of the CKDN2 gene and loss of heterozygosity in primary hepatocellular carcinoma
    • Piao Z, Park C, Lee JS, Yang CH, Choi KY, Kim H. Homozygous deletions of the CKDN2 gene and loss of heterozygosity in primary hepatocellular carcinoma. Cancer Lett 1998;122:201-207.
    • (1998) Cancer Lett , vol.122 , pp. 201-207
    • Piao, Z.1    Park, C.2    Lee, J.S.3    Yang, C.H.4    Choi, K.Y.5    Kim, H.6
  • 14
    • 0032484502 scopus 로고    scopus 로고
    • Allelotype analysis of hepatocellular carcinoma
    • Piao Z, Park C, Park J-H, Kim H. Allelotype analysis of hepatocellular carcinoma. Int J Cancer 1998;75:29-33.
    • (1998) Int J Cancer , vol.75 , pp. 29-33
    • Piao, Z.1    Park, C.2    Park, J.-H.3    Kim, H.4
  • 16
    • 0024284028 scopus 로고
    • A simple salting out procedure for extracting DNA from human nucleated cells
    • Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 1988;16:1215.
    • (1988) Nucleic Acids Res , vol.16 , pp. 1215
    • Miller, S.A.1    Dykes, D.D.2    Polesky, H.F.3
  • 18
    • 0142199720 scopus 로고    scopus 로고
    • Genetic alterations in hepatocellular carcinomas: Association between loss of chromosome 4q and p53 gene mutations
    • Rashid A, Wang J-S, Qian G-S, Lu B-X, Hamilton SR, Groopman JD. Genetic alterations in hepatocellular carcinomas: Association between loss of chromosome 4q and p53 gene mutations. Br J Cancer 1999;80:59-66.
    • (1999) Br J Cancer , vol.80 , pp. 59-66
    • Rashid, A.1    Wang, J.-S.2    Qian, G.-S.3    Lu, B.-X.4    Hamilton, S.R.5    Groopman, J.D.6
  • 19
    • 0029031943 scopus 로고
    • Frequent loss of heterozygosity on 6q at the emannose 6-phosphate/insulin-like growth factor II receptor locus in human hepatocellular tumors
    • De Souza AT, Hankins GR, Washingon MK, Fine RL, Orton TC, Jirtle RL. Frequdnt loss of heterozygosity on 6q at the emannose 6-phosphate/insulin-likd growth factor II receptor locus in human hepatocellular tumors. Oncogene 1995;10:1725-1729.
    • (1995) Oncogene , vol.10 , pp. 1725-1729
    • De Souza, A.T.1    Hankins, G.R.2    Washingon, M.K.3    Fine, R.L.4    Orton, T.B.5    Jirtle, R.L.6
  • 20
    • 0034093607 scopus 로고    scopus 로고
    • Relationship between loss of heterozygosity at microsatellite loci and computerized nuclear morphometry in hepatocellular carcinoma
    • Suzuki K, Hirooka Y, Tsujitani S, Yamane Y, Ikeguchi M, Kaibara N. Relationship between loss of heterozygosity at microsatellite loci and computerized nuclear morphometry in hepatocellular carcinoma. Anticancer Res 2000;20:1257-1262.
    • (2000) Anticancer Res , vol.20 , pp. 1257-1262
    • Suzuki, K.1    Hirooka, Y.2    Tsujitani, S.3    Yamane, Y.4    Ikeguchi, M.5    Kaibara, N.6
  • 21
    • 0031043705 scopus 로고    scopus 로고
    • Frequency of mutation and deletion of the tumor suppressor gene CDKN2A (MTS1/p16) in hepatocellular carcinoma from an Australian population
    • Biden K, Young J, Buttenshaw R, Searle J, Cooksley G, Xu D-B, Leggett B. Frequency of mutation and deletion of the tumor suppressor gene CDKN2A (MTS1/p16) in hepatocellular carcinoma from an Australian population. Hepatology 1997;25:593-597.
    • (1997) Hepatology , vol.25 , pp. 593-597
    • Biden, K.1    Young, J.2    Buttenshaw, R.3    Searle, J.4    Cooksley, G.5    Xu, D.-B.6    Leggett, B.7
  • 22
    • 0029129209 scopus 로고
    • Evidence for the presence of two tumor suppressor genes for hepatocellular carcinoma on chromosome 13q
    • Kuroki T, Fujiwara Y, Nakamori S, Imaoka S, Kanematsu T, Nakamura Y. Evidence for the presence of two tumor suppressor genes for hepatocellular carcinoma on chromosome 13q. Br J Cancer 1995;72:383-285.
    • (1995) Br J Cancer , vol.72 , pp. 383-285
    • Kuroki, T.1    Fujiwara, Y.2    Nakamori, S.3    Imaoka, S.4    Kanematsu, T.5    Nakamura, Y.6
  • 23
    • 0034090554 scopus 로고    scopus 로고
    • Allelic imbalance on 16q in small, unifocal hepatocellular carcinoma: Correlation with HBV and HCV infections and cellular proliferation rate
    • Gramantieri L, Trere D, Pession A, Piscaglia F, Masi L, Gaiani S, Mazziotti A, dt al. Allelic imbalance on 16q in small, unifocal hepatocellular carcinoma: Correlation with HBV and HCV infections and cellular proliferation rate. Dig Dis Sci 2000;45:306-311.
    • (2000) Dig Dis Sci , vol.45 , pp. 306-311
    • Gramantieri, L.1    Trere, D.2    Pession, A.3    Piscaglia, F.4    Masi, L.5    Gaiani, S.6    Mazziotti, A.7
  • 24
    • 15144361323 scopus 로고    scopus 로고
    • Concetted nonsymtenic allelic losses in hyperploid hepatocellular carcinoma as determined by a high-resolution allelorype
    • Boige V, Larent-Puig P, Fouchet P, Flejou JF, Monges G, Bedossa P, Biolac-Sage P, et al. Concetted nonsymtenic allelic losses in hyperploid hepatocellular carcinoma as determined by a high-resolution allelorype. Cancer Res 1997;57:1986-1990.
    • (1997) Cancer Res , vol.57 , pp. 1986-1990
    • Boige, V.1    Larent-Puig, P.2    Fouchet, P.3    Flejou, J.F.4    Monges, G.5    Bedossa, P.6    Biolac-Sage, P.7
  • 25
    • 0032955558 scopus 로고    scopus 로고
    • Multiple genetic alterations, 4128, a new suppressor region, and potential gender differences in human hepatocellular carcinoma
    • Hammond C, Jeffers L, Carr BI, Simon D. Multiple genetic alterations, 4128, a new suppressor region, and potential gender differences in human hepatocellular carcinoma. Hepatology 1999;29:1479-1485.
    • (1999) Hepatology , vol.29 , pp. 1479-1485
    • Hammond, C.1    Jeffers, L.2    Carr, B.I.3    Simon, D.4
  • 26
  • 27
    • 17544366381 scopus 로고    scopus 로고
    • Comprehensive allelorype study of hepatocellular carcinoma: Potential differences in pathways to hepatocellular carcinoma between hepatitis B virus-positive and -negative tumors
    • Okabe H, Ikai I, Matsuo K, Satoh S, Momi H, Kamikawa T, Katsura N, et al. Comprehensive allelorype study of hepatocellular carcinoma: Potential differences in pathways to hepatocellular carcinoma between hepatitis B virus-positive and -negative tumors. Hepatology 2000;31:1073-1079.
    • (2000) Hepatology , vol.31 , pp. 1073-1079
    • Okabe, H.1    Ikai, I.2    Matsuo, K.3    Satoh, S.4    Momi, H.5    Kamikawa, T.6    Katsura, N.7
  • 28
    • 0034037032 scopus 로고    scopus 로고
    • Quantitative evaluation ofgenomic instability as a possible predictor for development of hepatocellular carcinoma: Comparison of loss of heterozygosity and replication error
    • Kawai H, Suda T, Aoyagi Y, Isokawa O, Mita Y, Waguri N, Kuroiwa T, et al. Quantitative evaluation ofgenomic instability as a possible predictor for development of hepatocellular carcinoma: Comparison of loss of heterozygosity and replication error. Hepatology 2000;31:1246-1250.
    • (2000) Hepatology , vol.31 , pp. 1246-1250
    • Kawai, H.1    Suda, T.2    Aoyagi, Y.3    Isokawa, O.4    Mita, Y.5    Waguri, N.6    Kuroiwa, T.7
  • 29
    • 0030733924 scopus 로고    scopus 로고
    • Molecular mechanism of hepatocarcinogenesis
    • Sheu J-C. Molecular mechanism of hepatocarcinogenesis. J Gastroenterol Hepatol 1997;12:S309-S313.
    • (1997) J Gastroenterol Hepatol , vol.12
    • Sheu, J.-C.1
  • 31
    • 0026632471 scopus 로고
    • Loss of heterozygosiry on chromosome 16 in hepatocellular carcinoma
    • Sakai K, Nagahara H, Abe K, Obata H. Loss of heterozygosiry on chromosome 16 in hepatocellular carcinoma. J Gastroenterol Hepatol 1992;7:288-292.
    • (1992) J Gastroenterol Hepatol , vol.7 , pp. 288-292
    • Sakai, K.1    Nagahara, H.2    Abe, K.3    Obata, H.4
  • 32
    • 0033039991 scopus 로고    scopus 로고
    • Genetic aberrations detected by comparative genomic hybridization in hepatocellular carcinomas: Their relationship to clinicopathologic features
    • Kusano N, Shiraishi K, Kubo K, Oga A, Okita K, Sasaki, K. Genetic aberrations detected by comparative genomic hybridization in hepatocellular carcinomas: Their relationship to clinicopathologic features. Hepatology 1999;29:1858-1862.
    • (1999) Hepatology , vol.29 , pp. 1858-1862
    • Kusano, N.1    Shiraishi, K.2    Kubo, K.3    Oga, A.4    Okita, K.5    Sasaki, K.6
  • 33
    • 0034601378 scopus 로고    scopus 로고
    • Distinct chromosomal abnormality pattern in primary liver cancer of non-B, non-C patients
    • Marchio A, Peneau P, Meddeb M, Terris B, Tiollais P, Bernheim A, Dejean A. Distinct chromosomal abnormality pattern in primary liver cancer of non-B, non-C patients. Oncogene 2000;19:3733-3738.
    • (2000) Oncogene , vol.19 , pp. 3733-3738
    • Marchio, A.1    Peneau, P.2    Meddeb, M.3    Terris, B.4    Tiollais, P.5    Bernheim, A.6    Dejean, A.7
  • 35
    • 0032919172 scopus 로고    scopus 로고
    • Assessment of genetic changes in hepatocellular carcinoma by comparative genomic hybridization analysis: Relationship to disease stage, tumor size, and cirrhosis
    • Wong N, Lai P, Lee SW, Fan S, Pang E, Liew CT, Sheng Z, et al. Assessment of genetic changes in hepatocellular carcinoma by comparative genomic hybridization analysis: Relationship to disease stage, tumor size, and cirrhosis. Am J Pathol 1999;154:37-43.
    • (1999) Am J Pathol , vol.154 , pp. 37-43
    • Wong, N.1    Lai, P.2    Lee, S.W.3    Fan, S.4    Pang, E.5    Liew, C.T.6    Sheng, Z.7
  • 36
    • 0033843955 scopus 로고    scopus 로고
    • Recurrent chromosome alternations in hepatocellular carcinoma detected by comparative genomic hybridization
    • Guan XY, Fang Y, Sham JST, Kwong DLW, Zhang Y, Liang Q, Li H, et al. Recurrent chromosome alternations in hepatocellular carcinoma detected by comparative genomic hybridization. Genes Chromosomes Cancer 2000;29:110-116.
    • (2000) Genes Chromosomes Cancer , vol.29 , pp. 110-116
    • Guan, X.Y.1    Fang, Y.2    Sham, J.S.T.3    Kwong, D.L.W.4    Zhang, Y.5    Liang, Q.6    Li, H.7
  • 37
    • 0033651437 scopus 로고    scopus 로고
    • Marked genetic similarities between hepatitis B virus-positive and hepatitis C virus-positive hepatocellular carcinoma
    • Tornillo J, Carafa V, Richter J, Sauter G, Mock H, Minola E, Gambacorta M, et al. Marked genetic similarities between hepatitis B virus-positive and hepatitis C virus-positive hepatocellular carcinoma. J Pathol 2000;192:307-312.
    • (2000) J Pathol , vol.192 , pp. 307-312
    • Tornillo, J.1    Carafa, V.2    Richter, J.3    Sauter, G.4    Mock, H.5    Minola, E.6    Gambacorta, M.7
  • 38
    • 0033755177 scopus 로고    scopus 로고
    • Genomic aberrations in human hepatocellular carcinoma of differinf etiologies
    • Wong N, Lai P, Pang E, Fung L-F, Sheng Z, Wong V, Wang W, et al. Genomic aberrations in human hepatocellular carcinoma of differing etiologies. Clin Cancer Res 2000;6:4000-4009.
    • (2000) Clin Cancer Res , vol.6 , pp. 4000-4009
    • Wong, N.1    Lai, P.2    Pang, E.3    Fung, L.-F.4    Sheng, Z.5    Wong, V.6    Wang, W.7
  • 39
    • 0033862041 scopus 로고    scopus 로고
    • Chromosomal changes and clonaliry relationship between primary and recurrent hepatocellular carcinoma
    • Chen Y-J, Yeh S-H, Chen J-T, Wu C-C, Shu M-T, Tsai S-F, Chen P-J, et al. Chromosomal changes and clonaliry relationship between primary and recurrent hepatocellular carcinoma. Gastroenterology 2000;119:431-440.
    • (2000) Gastroenterology , vol.119 , pp. 431-440
    • Chen, Y.-J.1    Yeh, S.-H.2    Chen, J.-T.3    Wu, C.-C.4    Shu, M.-T.5    Tsai, S.-F.6    Chen, P.-J.7
  • 40
    • 0035150349 scopus 로고    scopus 로고
    • Human hepatocellular carcinoma is characterized by a highly consistent pattern of genomic imbalances, including frequent loss of 16q23.1-24.1
    • Balsara BR, Pei J, DeRienzo A, Simon D, Tosolini A, Lu YY, Shen F-M, et al. Human hepatocellular carcinoma is characterized by a highly consistent pattern of genomic imbalances, including frequent loss of 16q23.1-24.1. Genes Chromosomes Cancer 2001;30:245-253.
    • (2001) Genes Chromosomes Cancer , vol.30 , pp. 244-253
    • Balsara, B.R.1    Pei, J.2    DeRienzo, A.3    Simon, D.4    Tosolini, A.5    Lu, Y.Y.6    Shen, F.-M.7
  • 41
    • 17744391051 scopus 로고    scopus 로고
    • A comparison of DNA copy number changes detected by comparative genomic hybridization in malignancies of the liver, biliary tract and pancreas
    • Shiraishi K, Okita K, Kusano N, Harada T, Kondoh S, Okita S, Ryozawa S, et al. A comparison of DNA copy number changes detected by comparative genomic hybridization in malignancies of the liver, biliary tract and pancreas. Oncology 2001;60:151-161.
    • (2001) Oncology , vol.60 , pp. 151-161
    • Shiraishi, K.1    Okita, K.2    Kusano, N.3    Harada, T.4    Kondoh, S.5    Okita, S.6    Ryozawa, S.7
  • 43
  • 44
    • 0031853180 scopus 로고    scopus 로고
    • Deletion mapping of chromosome 4q in hepatocellular carcinoma
    • Piao Z, Park C, Park J-H, Kim H. Deletion mapping of chromosome 4q in hepatocellular carcinoma. Int J Cancer 1998;79:356-360.
    • (1998) Int J Cancer , vol.79 , pp. 356-360
    • Piao, Z.1    Park, C.2    Park, J.-H.3    Kim, H.4
  • 45
    • 0030031136 scopus 로고    scopus 로고
    • Alleleic loss on chromosome 4q and 16q in hepatocellular carcinoma: Assocation with elevated a-fetoprotein production
    • Yeh S-H, Chen P-J, Lai M-Y, Chen D-S. Alleleic loss on chromosome 4q and 16q in hepatocellular carcinoma: Assocation with elevated a-fetoprotein production. Gastroenterology 1996;110:184-192.
    • (1996) Gastroenterology , vol.110 , pp. 184-192
    • Yeh, S.-H.1    Chen, P.-J.2    Lai, M.-Y.3    Chen, D.-S.4
  • 46
    • 0028982642 scopus 로고
    • Accumulation of genetic changes during development and progression of hepatocellular carcinoma: Loss ofheterozygosity on chromosome arm 1p occurs at an early stage of hepatocarcinogenesis
    • Kuroki T, Fujiwara Y, Tsuchiya E, Nakamori S, Imaoka S, Kanematsu T, Nakamura Y. Accumulation of genetic changes during development and progression ofhepatocellular carcinoma: Loss of heterozygosity on chromosome arm 1p occurs at an early stage of hepatocarcinogenesis. Genes Chromosomes Cancer 1995;13:163-167.
    • (1995) Genes Chromosomes Cancer , vol.13 , pp. 163-167
    • Kuroki, T.1    Fujiwara, Y.2    Tsuchiya, E.3    Nakamori, S.4    Imaoka, S.5    Kanematsu, T.6    Nakamura, Y.7
  • 47
    • 0034025348 scopus 로고    scopus 로고
    • Fractional alleleic loss in non-end stage cirrhosis: Correlations with hepatocellular carcinoma development during follow-up
    • Roncalli M, Bianchi P, Grimaldi GC, Ricci D, Laghi J, Maggioni M, Opocher E, et al. Fractional alleleic loss in non-end stage cirrhosis: Correlations with hepatocellular carcinoma development during follow-up. Hepatology 2000;31:846-850.
    • (2000) Hepatology , vol.31 , pp. 846-850
    • Roncalli, M.1    Bianchi, P.2    Grimaldi, G.C.3    Ricci, D.4    Laghi, J.5    Maggioni, M.6    Opocher, E.7
  • 48
    • 0024263645 scopus 로고
    • Deletions in human chromosome arms 11p and 13q in primary hepatocellular carcinomas
    • Wang HP, Rogler CE. Deletions in human chromosome arms 11p and 13q in primary hepatocellular carcinomas. Cytogenet Cell Genet 1988;48:72-78.
    • (1988) Cytogenet Cell Genet , vol.48 , pp. 72-78
    • Wang, H.P.1    Rogler, C.E.2
  • 49
    • 0033369354 scopus 로고    scopus 로고
    • Loss of heterozygosity at chromosome 13q in hepatocellular carcinoma: Identification of three independent regions
    • Lin Y-W, Sheu J-C, Liu L-Y, Chen C-H, Lee H-S, Huang G-T, Wang J-T, et al. Loss of heterozygosity at chromosome 13q in hepatocellular carcinoma: Identification of three independent regions. Euro J Cancer 1999;35:1730-1734.
    • (1999) Euro J Cancer , vol.35 , pp. 1730-1734
    • Lin, Y.-W.1    Sheu, J.-C.2    Liu, L.-Y.3    Chen, C.-H.4    Lee, H.-S.5    Huang, G.-T.6    Wang, J.-T.7
  • 50
    • 0028084735 scopus 로고
    • Alternations of tumor suppressor genes and alleleic losses in human hepatocellular carcinomas in China
    • Fujimoto Y, Hampton LL, Wirth PJ, Wang NJ, Xie JP, Thorgeirsson SS. Alternations of tumor suppressor genes and alleleic losses in human hepatocellular carcinomas in China. Cancer Res 1994;54:281-285.
    • (1994) Cancer Res , vol.54 , pp. 281-285
    • Fujimoto, Y.1    Hampton, L.L.2    Wirth, P.J.3    Wang, N.J.4    Xie, J.P.5    Thorgeirsson, S.S.6
  • 51
    • 0030876720 scopus 로고    scopus 로고
    • Relationship between loss of heterozygosity of tumor suppressor genes and histologic differentiation in hepatocellular carcinoma
    • Piao Z, Kim H, Jeon BK, Lee WU, Park C. Relationship between loss of heterozygosity of tumor suppressor genes and histologic differentiation in hepatocellular carcinoma. Cancer 1997;80:865-872.
    • (1997) Cancer , vol.80 , pp. 865-872
    • Piao, Z.1    Kim, H.2    Jeon, B.K.3    Lee, W.U.4    Park, C.5
  • 52
    • 0028137784 scopus 로고
    • Allelotype and loss of heterozygosity of p53 in primary and recurrent hepatocellular carcinomas
    • Hsu H-C, Peng S-Y, Lai P-L, Sheu J-C, Chen D-S, Lin L-I, Slagle BL, et al. Allelotype and loss of heterozygosity of p53 in primary and recurrent hepatocellular carcinomas. Cancer 1994;73:42-47.
    • (1994) Cancer , vol.73 , pp. 42-47
    • Hsu, H.-C.1    Peng, S.-Y.2    Lai, P.-L.3    Sheu, J.-C.4    Chen, D.-S.5    Lin, L.-I.6    Slagle, B.L.7
  • 53
    • 0033606132 scopus 로고    scopus 로고
    • Deletion mapping on the short arm of chromosome 8 in hepatocellular carcinoma
    • Piao Z, Kim N-G, Kim H, Park C. Deletion mapping on the short arm of chromosome 8 in hepatocellular carcinoma. Cancer Lett 1999(a);138:227-232.
    • (1999) Cancer Lett , vol.138 , pp. 227-232
    • Piao, Z.1    Kim, N.-G.2    Kim, H.3    Park, C.4
  • 54
    • 0033803788 scopus 로고    scopus 로고
    • Identification of the gene for a novel liver-related putative tumor suppressor at a high-frequency loss of heterozygosity region of chromosome 8p23 in human hepatocellular carcinoma
    • Liao C, Zhao M, Song H, Uchida K, Yokoyama KK, Li T. Identification of the gene for a novel liver-related putative tumor suppressor at a high-frequency loss of heterozygosity region of chromosome 8p23 in human hepatocellular carcinoma. Hepatology 2000;32:721-727.
    • (2000) Hepatology , vol.32 , pp. 721-727
    • Liao, C.1    Zhao, M.2    Song, H.3    Uchida, K.4    Yokoyama, K.K.5    Li, T.6
  • 56
    • 0028935036 scopus 로고
    • Isolation of a candidate tumor suppressor gene on chromosome 8p21.3-p22 that is homologous to an extracellular domain of the PDGF receptor beta gene
    • Fujiwara Y, Ohata H, Kuroki T, Koyama K, Tsuchiya E, Monden M, Nakamura Y. Isolation of a candidate tumor suppressor gene on chromosome 8p21.3-p22 that is homologous to an extracellular domain of the PDGF receptor beta gene. Oncogene 1995;10:891-895.
    • (1995) Oncogene , vol.10 , pp. 891-895
    • Fujiwara, Y.1    Ohata, H.2    Kuroki, T.3    Koyama, K.4    Tsuchiya, E.5    Monden, M.6    Nakamtra, Y.7
  • 57
    • 0029866294 scopus 로고    scopus 로고
    • Detailed physical and deletion mapping of 8p with isolation of YAC clones from tumor suppressor loci involved in colorectal cancer
    • Farrington SM, Cunningham C, Boyle SM, Wyllie AH, Dunlop MG. Detailed physical and deletion mapping of 8p with isolation of YAC clones from tumor suppressor loci involved in colorectal cancer. Oncogene 1996;12:1803-1808.
    • (1996) Oncogene , vol.12 , pp. 1803-1808
    • Farrington, S.M.1    Cunningham, C.2    Boyle, S.M.3    Wyllie, A.H.4    Dunlop, M.G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.