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Volumn 23, Issue 6, 2002, Pages 1085-1088

Aβ conformational change is central to Alzheimer's disease

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; AMYLOID BETA PROTEIN; PEPTIDE; PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN; METAL;

EID: 0036860357     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-4580(02)00040-4     Document Type: Note
Times cited : (9)

References (28)
  • 1
    • 0031278270 scopus 로고    scopus 로고
    • Lack of apolipoprotein E dramatically reduces amyloid β-peptide deposition
    • Bales K.R., Verina T., Dodel R.C., Du Y., Altstiel L., Bender M.et al. Lack of apolipoprotein E dramatically reduces amyloid β-peptide deposition. Nat. Genet. 17:1997;263-264.
    • (1997) Nat. Genet. , vol.17 , pp. 263-264
    • Bales, K.R.1    Verina, T.2    Dodel, R.C.3    Du, Y.4    Altstiel, L.5    Bender, M.6
  • 2
    • 0034704198 scopus 로고    scopus 로고
    • Evidence for genetic linkage of Alzheimer's disease to chromosome 10q
    • Bertram L., Blacker D., Mullin K., Keeney D., Jones J., Basu S.et al. Evidence for genetic linkage of Alzheimer's disease to chromosome 10q. Science. 290:2000;2302-2303.
    • (2000) Science , vol.290 , pp. 2302-2303
    • Bertram, L.1    Blacker, D.2    Mullin, K.3    Keeney, D.4    Jones, J.5    Basu, S.6
  • 3
    • 0033564771 scopus 로고    scopus 로고
    • Expression of human apolipoprotein E3 or E4 in the brains of Apoe/Mice: Isoform-specific effects on neurodegeneration
    • Buttini M., Orth M., Bellosta S., Akeefe H., Pitas R.E., Wyss-Coray T.et al. Expression of human apolipoprotein E3 or E4 in the brains of Apoe/Mice: isoform-specific effects on neurodegeneration. J. Neurosci. 19:1999;4867-4880.
    • (1999) J. Neurosci. , vol.19 , pp. 4867-4880
    • Buttini, M.1    Orth, M.2    Bellosta, S.3    Akeefe, H.4    Pitas, R.E.5    Wyss-Coray, T.6
  • 5
    • 0034703979 scopus 로고    scopus 로고
    • Linkage of plasma Aβ42 to a quantitative locus on chromosome 10 in late-onset Alzheimer's disease pedigrees
    • Ertekin-Taner N., Graff-Radford N., Younkin L.H., Eckman C., Baker M., Adamson J.et al. Linkage of plasma Aβ42 to a quantitative locus on chromosome 10 in late-onset Alzheimer's disease pedigrees. Science. 290:2000;2303-2304.
    • (2000) Science , vol.290 , pp. 2303-2304
    • Ertekin-Taner, N.1    Graff-Radford, N.2    Younkin, L.H.3    Eckman, C.4    Baker, M.5    Adamson, J.6
  • 6
    • 0034718027 scopus 로고    scopus 로고
    • Biochemical detection of Aβ isoforms: Implications for pathogenesis, diagnosis, and treatment of Alzheimer's disease
    • Golde T.E., Eckman C.B., Younkin S.G. Biochemical detection of Aβ isoforms: implications for pathogenesis, diagnosis, and treatment of Alzheimer's disease. Biochim. Biophys. Acta. 1502:2000;172-187.
    • (2000) Biochim. Biophys. Acta , vol.1502 , pp. 172-187
    • Golde, T.E.1    Eckman, C.B.2    Younkin, S.G.3
  • 7
    • 0035943436 scopus 로고    scopus 로고
    • Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils
    • Gotz J., Chen F., van Dorpe J., Nitsch R.M. Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils. Science. 293:2001;1491-1495.
    • (2001) Science , vol.293 , pp. 1491-1495
    • Gotz, J.1    Chen, F.2    Van Dorpe, J.3    Nitsch, R.M.4
  • 8
    • 0034982951 scopus 로고    scopus 로고
    • Novel amyloid precursor protein mutation in an Iowa family with dementia and severe cerebral amyloid angiopathy
    • Grabowski T.J., Cho H.S., Vonsattel J.P.G., Rebeck G.W., Greenberg S.M. Novel amyloid precursor protein mutation in an Iowa family with dementia and severe cerebral amyloid angiopathy. Ann. Neurol. 49:2001;697-705.
    • (2001) Ann. Neurol. , vol.49 , pp. 697-705
    • Grabowski, T.J.1    Cho, H.S.2    Vonsattel, J.P.G.3    Rebeck, G.W.4    Greenberg, S.M.5
  • 9
    • 0030848338 scopus 로고    scopus 로고
    • Skeletal and cardiac myopathies in mice lacking utrophin and dystrophin: A model for Duchenne muscular dystrophy
    • Grady R.M., Teng H., Nichol M.C., Cunningham J.C., Wilkinson R.S., Sanes J.R. Skeletal and cardiac myopathies in mice lacking utrophin and dystrophin: a model for Duchenne muscular dystrophy. Cell. 90:1997;729-738.
    • (1997) Cell , vol.90 , pp. 729-738
    • Grady, R.M.1    Teng, H.2    Nichol, M.C.3    Cunningham, J.C.4    Wilkinson, R.S.5    Sanes, J.R.6
  • 11
    • 0032855097 scopus 로고    scopus 로고
    • Progress toward valid transgenic mouse models for Alzheimer's disease
    • Guenette S.Y., Tanzi R.E. Progress toward valid transgenic mouse models for Alzheimer's disease. Neurobiol. Aging. 20:1999;201-211.
    • (1999) Neurobiol. Aging , vol.20 , pp. 201-211
    • Guenette, S.Y.1    Tanzi, R.E.2
  • 12
    • 0034746840 scopus 로고    scopus 로고
    • Role of apoE/Abeta interactions in the pathogenesis of Alzheimer's disease and cerebral amyloid angiopathy
    • Holtzman D.M. Role of apoE/Abeta interactions in the pathogenesis of Alzheimer's disease and cerebral amyloid angiopathy. J. Mol. Neurosci. 17:2001;147-155.
    • (2001) J. Mol. Neurosci. , vol.17 , pp. 147-155
    • Holtzman, D.M.1
  • 13
    • 4243215848 scopus 로고    scopus 로고
    • Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease
    • Holtzman D.M., Bales K.R., Tenkova T., Fagan A.M., Parsadanian M., Sartorius L.J.et al. Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease. Proc. Natl. Acad. Sci. USA. 97:2000;2892-2897.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 2892-2897
    • Holtzman, D.M.1    Bales, K.R.2    Tenkova, T.3    Fagan, A.M.4    Parsadanian, M.5    Sartorius, L.J.6
  • 14
    • 17944382037 scopus 로고    scopus 로고
    • Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP
    • Lewis J., Dickson D.W., Lin W.L., Chisholm L., Corral A., Jones G.et al. Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP. Science. 293:2001;1487-1491.
    • (2001) Science , vol.293 , pp. 1487-1491
    • Lewis, J.1    Dickson, D.W.2    Lin, W.L.3    Chisholm, L.4    Corral, A.5    Jones, G.6
  • 15
    • 0034426011 scopus 로고    scopus 로고
    • Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein
    • Lewis J., McGowan E., Rockwood J., Melrose H., Nacharaju P., Van Slegtenhorst M.et al. Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein. Nat. Genet. 25:2001;402-405.
    • (2001) Nat. Genet. , vol.25 , pp. 402-405
    • Lewis, J.1    McGowan, E.2    Rockwood, J.3    Melrose, H.4    Nacharaju, P.5    Van Slegtenhorst, M.6
  • 16
    • 0034621824 scopus 로고    scopus 로고
    • Photoactivated-secretase inhibitors directed to the active site covalently label presenilin 1
    • Li Y.-M., Xu M., Lai M.-T., Huang Q., Castro J.L., Dimuzio-Mower J.et al. Photoactivated-secretase inhibitors directed to the active site covalently label presenilin 1. Nature. 405:2000;689-694.
    • (2000) Nature , vol.405 , pp. 689-694
    • Li, Y.-M.1    Xu, M.2    Lai, M.-T.3    Huang, Q.4    Castro, J.L.5    Dimuzio-Mower, J.6
  • 17
    • 0029813177 scopus 로고    scopus 로고
    • Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F β-amyloid precursor protein and Alzheimer's disease
    • Masliah E., Sisk A., Mallory M., Mucke L., Schenk D., Games D. Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F β-amyloid precursor protein and Alzheimer's disease. J. Neurosci. 16:1996;5795-5811.
    • (1996) J. Neurosci. , vol.16 , pp. 5795-5811
    • Masliah, E.1    Sisk, A.2    Mallory, M.3    Mucke, L.4    Schenk, D.5    Games, D.6
  • 18
    • 0035168927 scopus 로고    scopus 로고
    • Pathologic correlates of nondemented aging, mild cognitive impairment, and early-stage Alzheimer's disease
    • Morris J.C., Price J.L. Pathologic correlates of nondemented aging, mild cognitive impairment, and early-stage Alzheimer's disease. J. Mol. Neurosci. 17:2001;101-118.
    • (2001) J. Mol. Neurosci. , vol.17 , pp. 101-118
    • Morris, J.C.1    Price, J.L.2
  • 19
    • 0034704197 scopus 로고    scopus 로고
    • Susceptibility locus for Alzheimer's disease on chromosome 10
    • Myers A., Holmans P., Marshall H., Kwon J., Meyer D., Ramic D.et al. Susceptibility locus for Alzheimer's disease on chromosome 10. Science. 290:2000;2304-2305.
    • (2000) Science , vol.290 , pp. 2304-2305
    • Myers, A.1    Holmans, P.2    Marshall, H.3    Kwon, J.4    Meyer, D.5    Ramic, D.6
  • 21
    • 0029665096 scopus 로고    scopus 로고
    • Apolipoprotein E-ε4 alleles in cerebral amyloid angiopathy and cerebrovascular pathology associated with Alzheimer's disease
    • Premkuman D.R.D., Cohen D.L., Hedera P., Friedland R.P., Kalaria R.N. Apolipoprotein E-ε4 alleles in cerebral amyloid angiopathy and cerebrovascular pathology associated with Alzheimer's disease. Am. J. Pathol. 148:1996;2083-2095.
    • (1996) Am. J. Pathol. , vol.148 , pp. 2083-2095
    • Premkuman, D.R.D.1    Cohen, D.L.2    Hedera, P.3    Friedland, R.P.4    Kalaria, R.N.5
  • 22
    • 0032491494 scopus 로고    scopus 로고
    • Genetic neurodegenerative diseases: The human illness and transgenic models
    • Price D.L., Sisodia S.S., Borchelt D.R. Genetic neurodegenerative diseases: the human illness and transgenic models. Science. 282:1998;1079-1083.
    • (1998) Science , vol.282 , pp. 1079-1083
    • Price, D.L.1    Sisodia, S.S.2    Borchelt, D.R.3
  • 23
    • 0034849725 scopus 로고    scopus 로고
    • Neuron number in the entorhinal cortex and CA1 in preclinical Alzheimer disease
    • Price J.L., Ko A.I., Wade M.J., Tsou S.K., McKeel D.W., Morris J.C. Neuron number in the entorhinal cortex and CA1 in preclinical Alzheimer disease. Arch. Neurol. 58:2001;1395-1402.
    • (2001) Arch. Neurol. , vol.58 , pp. 1395-1402
    • Price, J.L.1    Ko, A.I.2    Wade, M.J.3    Tsou, S.K.4    McKeel, D.W.5    Morris, J.C.6
  • 24
    • 0032989712 scopus 로고    scopus 로고
    • Tangles and plaques in nondemented aging and "preclinical" Alzheimer's disease
    • Price J.L., Morris J.C. Tangles and plaques in nondemented aging and "preclinical" Alzheimer's disease. Ann. Neurol. 45:1999;358-368.
    • (1999) Ann. Neurol. , vol.45 , pp. 358-368
    • Price, J.L.1    Morris, J.C.2
  • 25
    • 0035066332 scopus 로고    scopus 로고
    • Alzheimer's disease: Genes, proteins, and therapy
    • Selkoe D.J. Alzheimer's disease: genes, proteins, and therapy. Physiol. Rev. 81:2001;741-766.
    • (2001) Physiol. Rev. , vol.81 , pp. 741-766
    • Selkoe, D.J.1
  • 28
    • 0033535553 scopus 로고    scopus 로고
    • Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity
    • Wolfe M.S., Xia W., Ostaszewski B.L., Diehl T.S., Kimberly W.T., Selkoe D.J. Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity. Nature. 398:1999;513-517.
    • (1999) Nature , vol.398 , pp. 513-517
    • Wolfe, M.S.1    Xia, W.2    Ostaszewski, B.L.3    Diehl, T.S.4    Kimberly, W.T.5    Selkoe, D.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.