-
1
-
-
0034077041
-
Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system
-
(2000)
Neuron
, vol.25
, pp. 239-252
-
-
Abeliovich, A.1
Schmitz, Y.2
Farinas, I.3
Choi-Lundberg, D.4
Ho, W.H.5
Castillo, P.E.6
Shinsky, N.7
Verdugo, J.M.8
Armanini, M.9
Ryan, A.10
Hynes, M.11
Phillips, H.12
Sulzer, D.13
Rosenthal, A.14
-
3
-
-
0029877297
-
A targeted mutation of the D3 dopamine receptor gene is associated with hyperactivity in mice
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 1945-1949
-
-
Accili, D.1
Fishburn, C.S.2
Drago, J.3
Steiner, H.4
Lachowicz, J.E.5
Park, B.H.6
Gauda, E.B.7
Lee, E.J.8
Cool, M.H.9
Sibley, D.R.10
Gerfen, C.R.11
Westphal, H.12
Fuchs, S.13
-
5
-
-
0001841467
-
TBASE: The relationalized database of transgenic animals and targeted mutations
-
Houdebine LM, editor. Transgenic animals: generation and use. Amsterdam: Harwood Academic Publishers, Overseas Publishers Association (OPA) Amsterdam
-
(1997)
, pp. 533-552
-
-
Anagnostopoulos, A.V.1
-
6
-
-
15844426692
-
Atm-deficient mice: A paradigm of ataxia telangiectasia
-
(1996)
Cell
, vol.86
, pp. 159-171
-
-
Barlow, C.1
Hirotsune, S.2
Paylor, R.3
Liyanage, M.4
Eckhaus, M.5
Collins, F.6
Shiloh, Y.7
Crawley, J.N.8
Ried, T.9
Tagle, D.10
Wynshaw-Boris, A.11
-
9
-
-
0028349997
-
Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues
-
(1994)
Genes Dev
, vol.8
, pp. 1019-1029
-
-
Brannan, C.I.1
Perkins, A.S.2
Vogel, K.S.3
Ratner, N.4
Nordlund, M.L.5
Reid, S.W.6
Buchberg, A.M.7
Jenkins, N.A.8
Parada, L.F.9
Copeland, N.G.10
-
14
-
-
0033578272
-
Behavioral phenotyping of transgenic and knockout mice: Experimental design and evaluation of general health, sensory functions, motor abilities, and specific behavioral tests
-
review
-
(1999)
Brain Res
, vol.835
, pp. 18-26
-
-
Crawley, J.N.1
-
15
-
-
0027955570
-
Inactivation of the N-CAM gene in mice results in size reduction of the olfactory bulb and deficits in spatial learning
-
(1994)
Nature
, vol.367
, pp. 455-459
-
-
Cremer, H.1
Lange, R.2
Christoph, A.3
Plomann, M.4
Vopper, G.5
Roes, J.6
Brown, R.7
Baldwin, S.8
Kraemer, P.9
Scheff, S.10
-
16
-
-
0028297308
-
Mice lacking nerve growth factor display perinatal loss of sensory and sympathetic neurons yet develop basal forebrain cholinergic neurons
-
(1994)
Cell
, vol.76
, pp. 1001-1011
-
-
Crowley, C.1
Spencer, S.D.2
Nishimura, M.C.3
Chen, K.S.4
Pitts-Meek, S.5
Armanini, M.P.6
Ling, L.H.7
MacMahon, S.B.8
Shelton, D.L.9
Levinson, A.D.10
-
18
-
-
0028589325
-
Altered striatal function in a mutant mouse lacking D1A dopamine receptors
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 12564-12568
-
-
Drago, J.1
Gerfen, C.R.2
Lachowicz, J.E.3
Steiner, H.4
Hollon, T.R.5
Love, P.E.6
Ooi, G.T.7
Grinberg, A.8
Lee, E.J.9
Huang, S.P.10
-
19
-
-
0029082383
-
Inactivation of the mouse Huntington's disease gene homolog Hdh
-
(1995)
Science
, vol.269
, pp. 407-410
-
-
Duyao, M.P.1
Auerbach, A.B.2
Ryan, A.3
Persichetti, F.4
Barnes, G.T.5
McNeil, S.M.6
Ge, P.7
Vonsattel, J.P.8
Gusella, J.F.9
Joyner, A.L.10
-
22
-
-
0030689779
-
Targeted inactivation of the X-linked adrenoleukodystrophy gene in mice
-
(1997)
J Neurosci Res
, vol.50
, pp. 829-843
-
-
Forss-Petter, S.1
Werner, H.2
Berger, J.3
Lassmann, H.4
Molzer, B.5
Schwab, M.H.6
Bernheimer, H.7
Zimmermann, F.8
Nave, K.A.9
-
23
-
-
0029982572
-
Targeted disruption of the mouse sphingolipid activator protein gene: A complex phenotype, including severe leukodystrophy and wide-spread storage of multiple sphingolipids
-
(1996)
Hum Mol Genet
, vol.5
, pp. 711-725
-
-
Fujita, N.1
Suzuki, K.2
Vanier, M.T.3
Popko, B.4
Maeda, N.5
Klein, A.6
Henseler, M.7
Sandhoff, K.8
Nakayasu, H.9
Suzuki, K.10
-
27
-
-
0027092647
-
Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice
-
(1992)
Science
, vol.258
, pp. 1903-1910
-
-
Grant, S.G.1
O'Dell, T.J.2
Karl, K.A.3
Stein, P.L.4
Soriano, P.5
Kandel, E.R.6
-
29
-
-
13144279323
-
Loss of bombesin-induced feeding suppression in gastrin-releasing peptide receptor-deficient mice
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 3188-3192
-
-
Hampton, L.L.1
Ladenheim, E.E.2
Akeson, M.3
Way, J.M.4
Weber, H.C.5
Sutliff, V.E.6
Jensen, R.T.7
Wine, L.J.8
Arnheiter, H.9
Battey, J.F.10
-
31
-
-
0032968642
-
Normal electrophysiological and behavioral responses to ethanol in mice lacking the long splice variant of the gamma2 subunit of the gamma-aminobutyrate type A receptor
-
(1999)
Neuropharmacology
, vol.38
, pp. 253-265
-
-
Homanics, G.E.1
Harrison, N.L.2
Quinlan, J.J.3
Krasowski, M.D.4
Rick, C.E.5
De Blas, A.L.6
Mehta, A.K.7
Kist, F.8
Mihalek, R.M.9
Aul, J.J.10
Firestone, L.L.11
-
32
-
-
12644290240
-
Mice devoid of gamma-aminobutyrate type A receptor beta3 subunit have epilepsy, cleft palate, and hypersensitive behavior
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 4143-4148
-
-
Homanics, G.E.1
DeLorey, T.M.2
Firestone, L.L.3
Quinlan, J.J.4
Handforth, A.5
Harrison, M.D.6
Krasowski, C.E.7
Rick, E.R.8
Korpi, R.9
Makela, M.H.10
Brilliant, N.11
Hagiwara, C.12
Ferguson, K.13
Snyder, R.W.14
Olsen, R.W.15
-
33
-
-
0030615289
-
Gene knockout of the alpha6 subunit of the gamma-aminobutyric acid type A receptor: Lack of effect on responses to ethanol, pentobarbital, and general anesthetics
-
(1997)
Mol Pharmacol
, vol.51
, pp. 588-596
-
-
Homanics, G.E.1
Ferguson, C.2
Quinlan, J.J.3
Daggett, J.4
Snyder, K.5
Lagenaur, C.6
Mi, Z.P.7
Wang, X.H.8
Grayson, D.R.9
Firestone, L.L.10
-
37
-
-
0031173051
-
The Evil proto-oncogene is required at midgestation for neural, heart, and paraxial mesenchyme development
-
(1997)
Mech Dev
, vol.65
, pp. 55-70
-
-
Hoyt, P.R.1
Bartholomew, C.2
Davis, A.J.3
Yutzey, K.4
Gamer, L.W.5
Potter, S.S.6
Ihle, J.N.7
Mucenski, M.L.8
-
39
-
-
0032828088
-
Developing mouse models of aging: A consideration of strain differences in age-related behavioral and neural parameters
-
(1999)
Neurobiol Aging
, vol.20
, pp. 137-145
-
-
Ingram, D.K.1
Jucker, M.2
-
41
-
-
0030294789
-
Enhanced LTP in mice deficient in the AMPA receptor GluR2
-
(1996)
Neuron
, vol.17
, pp. 945-956
-
-
Jia, Z.1
Agopyan, N.2
Miu, P.3
Xiong, Z.4
Henderson, J.5
Gerlai, R.6
Taverna, F.A.7
Velumian, A.8
MacDonald, J.9
Carlen, P.10
Abramow-Newerly, W.11
Roder, J.12
-
45
-
-
0030838736
-
Pituitary lactotroph hyperplasia and chronic hyperprolactinemia in dopamine D2 receptor-deficient mice
-
(1997)
Neuron
, vol.19
, pp. 103-113
-
-
Kelly, M.A.1
Rubinstein, M.2
Asa, S.L.3
Zhang, G.4
Saez, C.5
Bunzow, J.R.6
Allen, R.G.7
Hnasko, R.8
Ben-Jonathan, N.9
Grandy, D.K.10
Low, M.J.11
-
46
-
-
0031436897
-
An evaluation of what the mouse knockout experiments are telling us about mammalian behaviour
-
(1997)
BioEssays
, vol.19
, pp. 1091-1098
-
-
Keverne, E.B.1
-
47
-
-
0028329355
-
Disruption of the neurotrophin-3 receptor gene trkC eliminates la muscle afferents and results in abnormal movements
-
(1994)
Nature
, vol.368
, pp. 249-251
-
-
Klein, R.1
Silos-Santiago, I.2
Smeyne, R.J.3
Lira, S.A.4
Brambilla, R.5
Bryant, S.6
Zhang, L.7
Snider, W.D.8
Barbacid, M.9
-
50
-
-
0029838063
-
Neurogegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 9782-9787
-
-
Lebovitz, R.M.1
Zhang, H.2
Vogel, H.3
Cartwright, J.4
Dionne, L.5
Lu, N.6
Huang, S.7
Matzuk, M.M.8
-
52
-
-
0028276189
-
Myelination in the absence of myelin-associated glycoprotein
-
(1994)
Nature
, vol.369
, pp. 747-750
-
-
Li, C.1
Tropak, M.B.2
Gerlai, R.3
Clapoff, S.4
Abramow-Newerly, W.5
Trapp, B.6
Peterson, A.7
Roder, J.8
-
55
-
-
0030610850
-
Mouse model of GM2 activator deficiency manifests cerebellar pathology and motor impairment
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 8138-8143
-
-
Liu, Y.1
Hoffmann, A.2
Grinberg, A.3
Westphal, H.4
McDonald, M.P.5
Miller, K.M.6
Crawley, J.N.7
Sandhoff, K.8
Suzuki, K.9
Proia, R.L.10
-
57
-
-
0029007151
-
Tissue non-specific alkaline phosphatase is expressed in both embryonic and extraembryonic lineages during mouse embryogenesis but is not required for migration of primordial germ cells
-
(1995)
Development
, vol.121
, pp. 1487-1496
-
-
MacGregor, G.R.1
Zambrowicz, B.P.2
Soriano, P.3
-
61
-
-
15844382546
-
Targeted deletion in astrocyte intermediate filament (Gfap) alters neuronal physiology
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 6361-6366
-
-
McCall, M.A.1
Gregg, R.G.2
Behringer, R.R.3
Brenner, M.4
Delaney, C.L.5
Galbreath, E.J.6
Zhang, C.L.7
Pearce, R.A.8
Chiu, S.Y.9
Messing, A.10
-
62
-
-
13044251823
-
Attenuated sensitivity to neuroactive steroids in gamma-aminobutyrate type A receptor delta subunit knockout mice
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 12905-12910
-
-
Mihalek, R.M.1
Banerjee, P.K.2
Korpi, E.R.3
Quinlan, J.J.4
Firestone, L.L.5
Mi, Z.P.6
Lagenaur, C.7
Tretter, V.8
Sieghart, W.9
Anagnostaras, S.G.10
Sage, J.R.11
Fanselow, M.S.12
Guidotti, A.13
Spigelman, I.14
Li, Z.15
DeLorey, T.M.16
Olsen, R.W.17
Homanics, G.E.18
-
65
-
-
0032499277
-
Altered synaptic physiology and reduced susceptibility to kainate-induced seizures in GluR6-deficient mice
-
(1998)
Nature
, vol.392
, pp. 601-605
-
-
Mulle, C.1
Sailer, A.2
Perez-Otano, I.3
Dickinson-Anson, H.4
Castillo, P.E.5
Bureau, I.6
Maron, C.7
Gage, F.H.8
Mann, J.R.9
Bettler, B.10
-
66
-
-
0003514935
-
Delivering the knockout punch
-
(1996)
Nat Genet
, vol.13
, pp. 251-252
-
-
-
68
-
-
0031170915
-
The use of genetic "knockout" mice in behavioral endocrinology research
-
(1997)
Horm Behav
, vol.31
, pp. 188-196
-
-
Nelson, R.J.1
-
70
-
-
0031469707
-
Ectopically expressed CAG repeats cause intranuclear inclusions and a progressive late onset neurological phenotype in the mouse
-
(1997)
Cell
, vol.91
, pp. 753-763
-
-
Ordway, J.M.1
Tallaksen-Greene, S.2
Gutekunst, C.A.3
Bernstein, E.M.4
Cearley, J.A.5
Wiener, H.W.6
Dure, L.S.7
Lindsey, R.8
Hersch, S.M.9
Jope, R.S.10
Albin, R.L.11
Detloff, P.J.12
-
71
-
-
0030613669
-
Mice deficient in the alpha7 neuronal nicotinic acetylcholine receptor lack alpha-bungarotoxin binding sites and hippocampal fast nicotinic currents
-
(1997)
J Neurosci
, vol.17
, pp. 9165-9171
-
-
Orr-Urtreger, A.1
Goldner, F.M.2
Saeki, M.3
Lorenzo, I.4
Goldberg, L.5
De Biasi, M.6
Dani, J.A.7
Patrick, J.W.8
Beaudet, A.L.9
-
73
-
-
0029814483
-
Impaired cerebellar synaptic plasticity and motor performance in mice lacking the mGluR4 subtype of metabotropic glutamate receptor
-
(1996)
J Neurosci
, vol.16
, pp. 6364-6373
-
-
Pekhletski, R.1
Gerlai, R.2
Overstreet, L.S.3
Huang, X.P.4
Agopyan, N.5
Slater, N.T.6
Abramow-Newerly, W.7
Roder, J.C.8
Hampson, D.R.9
-
78
-
-
0030601355
-
Mutation of the Emx-1 homeobox gene disrupts the corpus callosum
-
(1996)
Dev Biol
, vol.178
, pp. 174-178
-
-
Qiu, M.1
Anderson, S.2
Chen, S.3
Meneses, J.J.4
Hevner, R.5
Kuwana, E.6
Pedersen, R.A.7
Rubenstein, J.L.8
-
79
-
-
13344278032
-
Chondrodysplasia and neurological abnormalities in ATF-2-deficient mice
-
(1996)
Nature
, vol.379
, pp. 262-265
-
-
Reimold, A.M.1
Grusby, M.J.2
Kosaras, B.3
Fries, J.W.4
Mori, R.5
Maniwa, S.6
Clauss, I.M.7
Collins, T.8
Sidman, R.L.9
Glimche, M.J.10
Glimcher, L.H.11
-
80
-
-
0029024135
-
Essential functions of synapsins I and II in synaptic vesicle regulation
-
(1995)
Nature
, vol.375
, pp. 488-493
-
-
Rosahl, T.W.1
Spillane, D.2
Missler, M.3
Herz, J.4
Selig, D.K.5
Wolff, J.R.6
Hammer, R.E.7
Malenka, R.C.8
Sudhof, T.C.9
-
83
-
-
0029113867
-
Mouse models of Tay-Sachs and Sandhoff diseases differ in neurologic phenotype and ganglioside metabolism
-
(1995)
Nat Genet
, vol.11
, pp. 170-176
-
-
Sango, K.1
Yamanaka, S.2
Hoffmann, A.3
Okuda, Y.4
Grinberg, A.5
Westphal, H.6
McDonald, M.P.7
Crawley, J.N.8
Sandhoff, K.9
Suzuki, K.10
-
85
-
-
0002854153
-
To save or not to save: The role of repositories in a period of rapidly expanding development of genetically engineered strains of mice
-
Houdebine LM, editor. Transgenic animals: generation and use. Amsterdam: Harwood Academic Publishers, Overseas Publishers Association (OPA) Amsterdam
-
(1997)
, pp. 525-532
-
-
Sharp, J.J.1
Mobraaten, L.E.2
-
88
-
-
0031018226
-
A mouse model for the learning and memory deficits associated with neurofibromatosis type I
-
(1997)
Nat Genet
, vol.15
, pp. 281-284
-
-
Silva, A.J.1
Frankland, P.W.2
Marowitz, Z.3
Friedman, E.4
Lazlo, G.5
Cioffi, D.6
Jacks, T.7
Bourtchuladze, R.8
-
90
-
-
0032055649
-
Deletion of the K(V)1.1 potassium channel causes epilepsy in mice
-
(1998)
Neuron
, vol.20
, pp. 809-819
-
-
Smart, S.L.1
Lopantsev, V.2
Zhang, C.L.3
Robbins, C.A.4
Wang, H.5
Chiu, S.Y.6
Schwartzkroin, P.A.7
Messing, A.8
Tempel, B.L.9
-
91
-
-
0028331599
-
Severe sensory and sympathetic neuropathies in mice carrying a disrupted Trk/NGF receptor gene
-
(1994)
Nature
, vol.368
, pp. 246-249
-
-
Smeyne, R.J.1
Klein, R.2
Schnapp, A.3
Long, L.K.4
Bryant, S.5
Lewin, A.6
Lira, S.A.7
Lewin, A.8
Barbacid, M.9
-
92
-
-
0029944159
-
Sp4, a member of the Sp1-family of zinc finger transcription factors, is required for normal murine growth, viability, and male fertility
-
(1996)
Dev Biol
, vol.176
, pp. 284-299
-
-
Supp, D.M.1
Witte, D.P.2
Branford, W.W.3
Smith, E.P.4
Potter, S.S.5
-
95
-
-
0028246435
-
Fmr1 knockout mice: A model to study fragile X mental retardation
-
(1994)
Cell
, vol.78
, pp. 23-33
-
-
-
96
-
-
0030461289
-
Inner ear defects induced by null mutation of the isk gene
-
(1996)
Neuron
, vol.17
, pp. 1251-1264
-
-
Vetter, D.E.1
Mann, J.R.2
Wangemann, P.3
Liu, J.4
McLaughlin, K.J.5
Lesage, F.6
Marcus, D.C.7
Lazdunski, M.8
Heinemann, S.F.9
Barhanin, J.10
-
99
-
-
0029061551
-
Targeted disruption of the low-affinity leukemia inhibitory factor receptor gene causes placental, skeletal, neural and metabolic defects and results in perinatal death
-
(1995)
Development
, vol.121
, pp. 1283-1299
-
-
Ware, C.B.1
Horowitz, M.C.2
Renshaw, B.R.3
Hunt, J.S.4
Liggitt, D.5
Koblar, S.A.6
Gliniak, B.C.7
McKenna, H.J.8
Papayannopoulou, T.9
Thoma, B.10
-
104
-
-
0027959501
-
Targeted disruption of the Hexa gene results in mice with biochemical and pathologic features of Tay-Sachs disease
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 9975-9979
-
-
Yamanaka, S.1
Johnson, M.D.2
Grinberg, A.3
Westphal, H.4
Crawley, J.N.5
Taniike, M.6
Suzuki, K.7
Proia, R.L.8
|