메뉴 건너뛰기




Volumn 34, Issue 11, 2002, Pages 1395-1400

Animal models of oxidative stress, aging, and therapeutic antioxidant interventions

Author keywords

Aging; Antioxidants; Mitochondria; Oxidative stress

Indexed keywords

ANTIOXIDANT; CATALASE; NUCLEIC ACID; SUPEROXIDE DISMUTASE;

EID: 0036828581     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1357-2725(02)00086-9     Document Type: Review
Times cited : (87)

References (41)
  • 1
    • 0021288856 scopus 로고
    • Determination of the production of superoxide radicals and hydrogen peroxide in mitochondria
    • Boveris A. Determination of the production of superoxide radicals and hydrogen peroxide in mitochondria. Methods Enzymol. 105:1984;429-435.
    • (1984) Methods Enzymol. , vol.105 , pp. 429-435
    • Boveris, A.1
  • 2
    • 0018776894 scopus 로고
    • Hydroperoxide metabolism in mammalian organs
    • Chance B., Sies H., Boveris A. Hydroperoxide metabolism in mammalian organs. Physiol. Rev. 59(3):1979;527-605.
    • (1979) Physiol. Rev. , vol.59 , Issue.3 , pp. 527-605
    • Chance, B.1    Sies, H.2    Boveris, A.3
  • 4
    • 0034693038 scopus 로고    scopus 로고
    • Superoxide reacts with nitric oxide to nitrate tyrosine at physiological pH via peroxynitrite
    • Reiter C.D., Teng R.J., Beckman J.S. Superoxide reacts with nitric oxide to nitrate tyrosine at physiological pH via peroxynitrite. J. Biol. Chem. 275(42):2000;32460-32466.
    • (2000) J. Biol. Chem. , vol.275 , Issue.42 , pp. 32460-32466
    • Reiter, C.D.1    Teng, R.J.2    Beckman, J.S.3
  • 5
    • 0036155396 scopus 로고    scopus 로고
    • Chronic treatment with a superoxide dismutase mimetic prevents vascular remodeling and progression of hypertension in salt-loaded stroke-prone spontaneously hypertensive rats
    • Park J.B.et al. Chronic treatment with a superoxide dismutase mimetic prevents vascular remodeling and progression of hypertension in salt-loaded stroke-prone spontaneously hypertensive rats. Am. J. Hypertens. 15(1 Pt. 1):2002;78-84.
    • (2002) Am. J. Hypertens , vol.15 , Issue.1 PART 1 , pp. 78-84
    • Park, J.B.1
  • 6
    • 0035960677 scopus 로고    scopus 로고
    • Endothelial dysfunction, oxidative stress, and risk of cardiovascular events in patients with coronary artery disease
    • Heitzer T.et al. Endothelial dysfunction, oxidative stress, and risk of cardiovascular events in patients with coronary artery disease. Circulation. 104(22):2001;2673-2678.
    • (2001) Circulation , vol.104 , Issue.22 , pp. 2673-2678
    • Heitzer, T.1
  • 7
    • 0028827252 scopus 로고
    • Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase
    • Li Y.et al. Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase. Nat. Genet. 11(4):1995;376-381.
    • (1995) Nat. Genet. , vol.11 , Issue.4 , pp. 376-381
    • Li, Y.1
  • 8
    • 0034769530 scopus 로고    scopus 로고
    • Relationship between increased longevity and stress resistance as assessed through gerontogene mutations in Caenorhabditis elegans
    • Johnson T.E.et al. Relationship between increased longevity and stress resistance as assessed through gerontogene mutations in Caenorhabditis elegans. Exp. Gerontol. 36(10):2001;1609-1617.
    • (2001) Exp. Gerontol. , vol.36 , Issue.10 , pp. 1609-1617
    • Johnson, T.E.1
  • 9
    • 0032782364 scopus 로고    scopus 로고
    • The daf-2 gene network for longevity regulates oxidative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans
    • Honda Y., Honda S. The daf-2 gene network for longevity regulates oxidative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans. FASEB J. 13(11):1999;1385-1393.
    • (1999) FASEB J. , vol.13 , Issue.11 , pp. 1385-1393
    • Honda, Y.1    Honda, S.2
  • 10
    • 0036254145 scopus 로고    scopus 로고
    • Rejuvenating views of the ageing process
    • Helfand S.L., Inouye S.K. Rejuvenating views of the ageing process. Nat. Rev. Genet. 3(2):2002;149-153.
    • (2002) Nat. Rev. Genet. , vol.3 , Issue.2 , pp. 149-153
    • Helfand, S.L.1    Inouye, S.K.2
  • 11
    • 0025004091 scopus 로고
    • Increased life-span of age-1 mutants in Caenorhabditis elegans and lower gompertz rate of aging
    • Johnson T.E. Increased life-span of age-1 mutants in Caenorhabditis elegans and lower gompertz rate of aging. Science. 249(4971):1990;908-912.
    • (1990) Science , vol.249 , Issue.4971 , pp. 908-912
    • Johnson, T.E.1
  • 12
    • 0027515616 scopus 로고
    • Aging and resistance to oxidative damage in Caenorhabditis elegans
    • Larsen P.L. Aging and resistance to oxidative damage in Caenorhabditis elegans. Proc. Natl. Acad. Sci. U.S.A. 90(19):1993;8905-8909.
    • (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , Issue.19 , pp. 8905-8909
    • Larsen, P.L.1
  • 13
    • 0027197284 scopus 로고
    • Oxidative stress and ageing in Caenorhabditis elegans
    • Vanfleteren J.R. Oxidative stress and ageing in Caenorhabditis elegans. Biochem. J. 292(Pt. 2):1993;605-608.
    • (1993) Biochem. J. , vol.292 , Issue.PART 2 , pp. 605-608
    • Vanfleteren, J.R.1
  • 14
    • 0032908347 scopus 로고    scopus 로고
    • FLP recombinase-mediated induction of Cu/Zn-superoxide dismutase transgene expression can extend the life span of adult drosophila melanogaster flies (in process citation)
    • Sun J., Tower J. FLP recombinase-mediated induction of Cu/Zn-superoxide dismutase transgene expression can extend the life span of adult drosophila melanogaster flies (in process citation). Mol. Cell. Biol. 19(1):1999;216-228.
    • (1999) Mol. Cell. Biol. , vol.19 , Issue.1 , pp. 216-228
    • Sun, J.1    Tower, J.2
  • 15
    • 0031864164 scopus 로고    scopus 로고
    • Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons
    • Parkes T.L.et al. Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons. Nat. Genet. 19(2):1998;171-174.
    • (1998) Nat. Genet. , vol.19 , Issue.2 , pp. 171-174
    • Parkes, T.L.1
  • 16
    • 0035989388 scopus 로고    scopus 로고
    • Induced over-expression of mitochondrial Mn-superoxide dismutase extends the life span of adult Drosophila melanogaster
    • J. Sun, et al., Induced over-expression of mitochondrial Mn-superoxide dismutase extends the life span of adult Drosophila melanogaster, Genetics 161 (2) (2002) 661-672.
    • (2002) Genetics , vol.161 , Issue.2 , pp. 661-672
    • Sun, J.1
  • 17
    • 0031916984 scopus 로고    scopus 로고
    • The free radical theory of aging matures
    • Beckman K.B., Ames B.N. The free radical theory of aging matures. Physiol. Rev. 78(2):1998;547-581.
    • (1998) Physiol. Rev. , vol.78 , Issue.2 , pp. 547-581
    • Beckman, K.B.1    Ames, B.N.2
  • 18
    • 0032563949 scopus 로고    scopus 로고
    • Life extension and stress resistance in Caenorhabditis elegans modulated by the tkr-1 gene (in process citation)
    • Murakami S., Johnson T.E. Life extension and stress resistance in Caenorhabditis elegans modulated by the tkr-1 gene (in process citation). Curr. Biol. 8(19):1998;1091-1094.
    • (1998) Curr. Biol. , vol.8 , Issue.19 , pp. 1091-1094
    • Murakami, S.1    Johnson, T.E.2
  • 19
    • 0034284973 scopus 로고    scopus 로고
    • Extension of life-span with superoxide dismutase/catalase mimetics
    • Melov S.et al. Extension of life-span with superoxide dismutase/catalase mimetics. Science. 289(5484):2000;1567-1569.
    • (2000) Science , vol.289 , Issue.5484 , pp. 1567-1569
    • Melov, S.1
  • 20
    • 0002296980 scopus 로고    scopus 로고
    • Salen-manganese complexes: Combined superoxide dismutase/catalase mimics with broad pharmacological efficacy
    • Doctrow S.R.et al. Salen-manganese complexes: combined superoxide dismutase/catalase mimics with broad pharmacological efficacy. Adv. Pharmacol. 38:1997;247-269.
    • (1997) Adv. Pharmacol. , vol.38 , pp. 247-269
    • Doctrow, S.R.1
  • 21
    • 0027170452 scopus 로고
    • Salen-manganese complexes are superoxide dismutase-mimics
    • Baudry M.et al. Salen-manganese complexes are superoxide dismutase-mimics. Biochem. Biophys. Res. Commun. 192(2):1993;964-968.
    • (1993) Biochem. Biophys. Res. Commun. , vol.192 , Issue.2 , pp. 964-968
    • Baudry, M.1
  • 22
    • 0029680965 scopus 로고    scopus 로고
    • Role of oxidant stress in the adult respiratory distress syndrome: Evaluation of a novel antioxidant strategy in a porcine model of endotoxin-induced acute lung injury
    • Gonzalez P.K.et al. Role of oxidant stress in the adult respiratory distress syndrome: evaluation of a novel antioxidant strategy in a porcine model of endotoxin-induced acute lung injury. Shock. 6(Suppl. 1):1996;S23-S26.
    • (1996) Shock , vol.6 , Issue.SUPPL. 1
    • Gonzalez, P.K.1
  • 23
    • 0031562673 scopus 로고    scopus 로고
    • Prevention and suppression of autoimmune encephalomyelitis by EUK-8, a synthetic catalytic scavenger of oxygen-reactive metabolites
    • Malfroy B.et al. Prevention and suppression of autoimmune encephalomyelitis by EUK-8, a synthetic catalytic scavenger of oxygen-reactive metabolites. Cell. Immunol. 177(1):1997;62-68.
    • (1997) Cell. Immunol. , vol.177 , Issue.1 , pp. 62-68
    • Malfroy, B.1
  • 24
    • 0031911994 scopus 로고    scopus 로고
    • Synthetic combined superoxide dismutase/catalase mimetics are protective as a delayed treatment in a rat stroke model: A key role for reactive oxygen species in ischemic brain injury
    • Baker K.et al. Synthetic combined superoxide dismutase/catalase mimetics are protective as a delayed treatment in a rat stroke model: a key role for reactive oxygen species in ischemic brain injury. J. Pharmacol. Exp. Ther. 284(1):1998;215-221.
    • (1998) J. Pharmacol. Exp. Ther. , vol.284 , Issue.1 , pp. 215-221
    • Baker, K.1
  • 25
    • 0033578309 scopus 로고    scopus 로고
    • EUK-134, a synthetic superoxide dismutase and catalase mimetic, prevents oxidative stress and attenuates kainate-induced neuropathology
    • Rong Y.et al. EUK-134, a synthetic superoxide dismutase and catalase mimetic, prevents oxidative stress and attenuates kainate-induced neuropathology. Proc. Natl. Acad. Sci. U.S.A. 96(17):1999;9897-9902.
    • (1999) Proc. Natl. Acad. Sci. U.S.A. , vol.96 , Issue.17 , pp. 9897-9902
    • Rong, Y.1
  • 26
    • 0035947221 scopus 로고    scopus 로고
    • Synthetic superoxide dismutase/catalase mimetics reduce oxidative stress and prolong survival in a mouse amyotrophic lateral sclerosis model
    • Jung C.et al. Synthetic superoxide dismutase/catalase mimetics reduce oxidative stress and prolong survival in a mouse amyotrophic lateral sclerosis model. Neurosci. Lett. 304(3):2001;157-160.
    • (2001) Neurosci. Lett. , vol.304 , Issue.3 , pp. 157-160
    • Jung, C.1
  • 27
    • 0034853453 scopus 로고    scopus 로고
    • Attenuation of staurosporine-induced apoptosis, oxidative stress, and mitochondrial dysfunction by synthetic superoxide dismutase and catalase mimetics, in cultured cortical neurons
    • Pong K.et al. Attenuation of staurosporine-induced apoptosis, oxidative stress, and mitochondrial dysfunction by synthetic superoxide dismutase and catalase mimetics, in cultured cortical neurons. Exp. Neurol. 171(1):2001;84-97.
    • (2001) Exp. Neurol. , vol.171 , Issue.1 , pp. 84-97
    • Pong, K.1
  • 28
    • 0029866991 scopus 로고    scopus 로고
    • Beta-amyloid toxicity in organotypic hippocampal cultures: Protection by EUK-8, a synthetic catalytic free radical scavenger
    • Bruce A.J., Malfroy B., Baudry M. beta-amyloid toxicity in organotypic hippocampal cultures: protection by EUK-8, a synthetic catalytic free radical scavenger. Proc. Natl. Acad. Sci. U.S.A. 93(6):1996;2312-2316.
    • (1996) Proc. Natl. Acad. Sci. U.S.A. , vol.93 , Issue.6 , pp. 2312-2316
    • Bruce, A.J.1    Malfroy, B.2    Baudry, M.3
  • 29
    • 0028220114 scopus 로고
    • Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster
    • Orr W.C., Sohal R.S. Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster. Science. 263(5150):1994;1128-1130.
    • (1994) Science , vol.263 , Issue.5150 , pp. 1128-1130
    • Orr, W.C.1    Sohal, R.S.2
  • 30
    • 0031940986 scopus 로고    scopus 로고
    • A novel neurological phenotype in mice lacking mitochondrial manganese superoxide dismutase
    • Melov S.et al. A novel neurological phenotype in mice lacking mitochondrial manganese superoxide dismutase. Nat. Genet. 18(2):1998;159-163.
    • (1998) Nat. Genet. , vol.18 , Issue.2 , pp. 159-163
    • Melov, S.1
  • 31
    • 0035503501 scopus 로고    scopus 로고
    • Lifespan extension and rescue of spongiform encephalopathy in superoxide dismutase 2 nullizygous mice treated with superoxide dismutase-catalase mimetics
    • Melov S.et al. Lifespan extension and rescue of spongiform encephalopathy in superoxide dismutase 2 nullizygous mice treated with superoxide dismutase-catalase mimetics. J. Neurosci. 21(21):2001;8348-8353.
    • (2001) J. Neurosci. , vol.21 , Issue.21 , pp. 8348-8353
    • Melov, S.1
  • 32
    • 13044285432 scopus 로고    scopus 로고
    • Mitochondrial disease in superoxide dismutase 2 mutant mice
    • Melov S.et al. Mitochondrial disease in superoxide dismutase 2 mutant mice. Proc. Natl. Acad. Sci. U.S.A. 96(3):1999;846-851.
    • (1999) Proc. Natl. Acad. Sci. U.S.A. , vol.96 , Issue.3 , pp. 846-851
    • Melov, S.1
  • 33
    • 15844393658 scopus 로고    scopus 로고
    • Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury
    • Reaume A.G.et al. Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury. Nat. Genet. 13(1):1996;43-47.
    • (1996) Nat. Genet. , vol.13 , Issue.1 , pp. 43-47
    • Reaume, A.G.1
  • 34
    • 0029064709 scopus 로고
    • Mice lacking extracellular superoxide dismutase are more sensitive to hyperoxia
    • Carlsson L.M.et al. Mice lacking extracellular superoxide dismutase are more sensitive to hyperoxia. Proc. Natl. Acad. Sci. U.S.A. 92(14):1995;6264-6268.
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , Issue.14 , pp. 6264-6268
    • Carlsson, L.M.1
  • 35
    • 0001389985 scopus 로고    scopus 로고
    • A fraction of yeast Cu/Zn superoxide dismutase and its metallochaperone, CCS, localize to the intermembrane space of mitochondria: A physiological role for SOD1 in guarding against mitochondrial oxidative damage
    • Sturtz L.A.et al. A fraction of yeast Cu/Zn superoxide dismutase and its metallochaperone, CCS, localize to the intermembrane space of mitochondria: a physiological role for SOD1 in guarding against mitochondrial oxidative damage. J. Biol. Chem. 10:2001;10.
    • (2001) J. Biol. Chem. , vol.10 , pp. 10
    • Sturtz, L.A.1
  • 36
    • 0028040278 scopus 로고
    • Human copper-zinc superoxide dismutase transgenic mice are highly resistant to reperfusion injury after focal cerebral ischemia
    • Yang G., Chan P.H.et al. Human copper-zinc superoxide dismutase transgenic mice are highly resistant to reperfusion injury after focal cerebral ischemia. Stroke. 25(1):1994;165-170.
    • (1994) Stroke , vol.25 , Issue.1 , pp. 165-170
    • Yang, G.1    Chan, P.H.2
  • 37
    • 0029781555 scopus 로고    scopus 로고
    • The protective role of manganese superoxide dismutase against adriamycin-induced acute cardiac toxicity in transgenic mice
    • published erratum appears in J. Clin. Invest. 99 (5) (1997) 1141
    • Yen H.C., Oberley T.D.et al. The protective role of manganese superoxide dismutase against adriamycin-induced acute cardiac toxicity in transgenic mice. J. Clin. Invest. 98(5):1996;1253-1260. (published erratum appears in J. Clin. Invest. 99 (5) (1997) 1141).
    • (1996) J. Clin. Invest. , vol.98 , Issue.5 , pp. 1253-1260
    • Yen, H.C.1    Oberley, T.D.2
  • 38
    • 0032889085 scopus 로고    scopus 로고
    • Mice overexpressing extracellular superoxide dismutase have increased resistance to focal cerebral ischemia
    • Sheng H., Bart R.D.et al. Mice overexpressing extracellular superoxide dismutase have increased resistance to focal cerebral ischemia. Neuroscience. 88(1):1999;185-191.
    • (1999) Neuroscience , vol.88 , Issue.1 , pp. 185-191
    • Sheng, H.1    Bart, R.D.2
  • 39
    • 0030971057 scopus 로고    scopus 로고
    • Mice deficient in cellular glutathione peroxidase develop normally and show no increased sensitivity to hyperoxia
    • Ho Y.S., Magnenat J.L.et al. Mice deficient in cellular glutathione peroxidase develop normally and show no increased sensitivity to hyperoxia. J. Biol. Chem. 272(26):1997;16644-16651.
    • (1997) J. Biol. Chem. , vol.272 , Issue.26 , pp. 16644-16651
    • Ho, Y.S.1    Magnenat, J.L.2
  • 40
    • 0028648888 scopus 로고
    • Transgenic glutathione peroxidase mouse models for neuroprotection studies
    • Mirault M.E., Tremblay A.et al. Transgenic glutathione peroxidase mouse models for neuroprotection studies. Ann. N.Y. Acad. Sci. 738:1994;104-115.
    • (1994) Ann. N.Y. Acad. Sci. , vol.738 , pp. 104-115
    • Mirault, M.E.1    Tremblay, A.2
  • 41
    • 0033859495 scopus 로고    scopus 로고
    • Low glutathione peroxidase activity in Gpx1 knockout mice protects jejunum crypts from gamma-irradiation damage
    • R.S. Esworthy, et al., Low glutathione peroxidase activity in Gpx1 knockout mice protects jejunum crypts from gamma-irradiation damage, Am. J. Physiol. Gastrointest. Liver Physiol. 279 (2000) G426-G436.
    • (2000) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.279
    • Esworthy, R.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.