메뉴 건너뛰기




Volumn 4, Issue 5, 2002, Pages 444-451

Advances towards targetable adenovirus vectors for gene therapy

Author keywords

Adenovirus vector; Gene therapy; Penton base; Targeted vectors

Indexed keywords

ADENOVIRUS VECTOR; ALPHA5 INTEGRIN; APOLIPOPROTEIN E; CELL SURFACE RECEPTOR; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 2; INTEGRIN; MACROGOL; METHACRYLIC ACID DERIVATIVE; VIRUS PROTEIN; VIRUS RECEPTOR;

EID: 0036819756     PISSN: 14648431     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (23)

References (54)
  • 1
    • 0034283437 scopus 로고    scopus 로고
    • Adenoviral vectors - New insights
    • Nemerow GR: Adenoviral vectors - new insights. Trends Microbiol (2000) 8(9):391-394.
    • (2000) Trends Microbiol. , vol.8 , Issue.9 , pp. 391-394
    • Nemerow, G.R.1
  • 2
    • 0034663422 scopus 로고    scopus 로고
    • Cell receptors involved in adenovirus entry
    • Nemerow GR: Cell receptors involved in adenovirus entry. Virology (2000) 274(1):1-4.
    • (2000) Virology , vol.274 , Issue.1 , pp. 1-4
    • Nemerow, G.R.1
  • 3
    • 0029939555 scopus 로고    scopus 로고
    • Adenovirus interaction with distinct integrins mediates separate events in cell entry and gene delivery to hematopoietic cells
    • Huang S, Kamata T, Takada Y, Ruggeri ZM, Nemerow GR: Adenovirus interaction with distinct integrins mediates separate events in cell entry and gene delivery to hematopoietic cells. J Virol (1996) 70(7):4502-4508.
    • (1996) J. Virol. , vol.70 , Issue.7 , pp. 4502-4508
    • Huang, S.1    Kamata, T.2    Takada, Y.3    Ruggeri, Z.M.4    Nemerow, G.R.5
  • 4
    • 0029826879 scopus 로고    scopus 로고
    • Comparative analysis of adenovirus fiber-cell interaction: Adenovirus type 2 (Ad2) and Ad9 utilize the same cellular fiber receptor but use different binding strategies for attachment
    • Roelvink PW, Kovesdi I, Wickham TJ: Comparative analysis of adenovirus fiber-cell interaction: Adenovirus type 2 (Ad2) and Ad9 utilize the same cellular fiber receptor but use different binding strategies for attachment. J Virol (1996) 70(11):7614-7621.
    • (1996) J. Virol. , vol.70 , Issue.11 , pp. 7614-7621
    • Roelvink, P.W.1    Kovesdi, I.2    Wickham, T.J.3
  • 5
    • 0034890820 scopus 로고    scopus 로고
    • Heparan sulfate glycosaminoglycans are receptors sufficient to mediate the initial binding of adenovirus types 2 and 5
    • Dechecchi MC, Melotti P, Bonizzato A, Santacatterina M, Chilosi M, Cabrini G: Heparan sulfate glycosaminoglycans are receptors sufficient to mediate the initial binding of adenovirus types 2 and 5. J Virol (2001) 75(18):8772-8780.
    • (2001) J. Virol. , vol.75 , Issue.18 , pp. 8772-8780
    • Dechecchi, M.C.1    Melotti, P.2    Bonizzato, A.3    Santacatterina, M.4    Chilosi, M.5    Cabrini, G.6
  • 6
    • 0031000327 scopus 로고    scopus 로고
    • Selective targeting of human cells by a chimeric adenovirus vector containing a modified fiber protein
    • Stevenson SC, Rollence M, Marshall-Neff J, McClelland A: Selective targeting of human cells by a chimeric adenovirus vector containing a modified fiber protein. J Virol (1997) 71(6):4782-4790.
    • (1997) J. Virol. , vol.71 , Issue.6 , pp. 4782-4790
    • Stevenson, S.C.1    Rollence, M.2    Marshall-Neff, J.3    McClelland, A.4
  • 8
    • 0033989720 scopus 로고    scopus 로고
    • Adenovirus vector pseudotyping in fiber-expressing cell lines: Improved transduction of Epstein-Barr virus-transformed B cells
    • Von Seggern DJ, Huang S, Fleck SK, Stevenson SC, Nemerow GR: Adenovirus vector pseudotyping in fiber-expressing cell lines: Improved transduction of Epstein-Barr virus-transformed B cells. J Virol (2000) 74(1):354-362.
    • (2000) J. Virol. , vol.74 , Issue.1 , pp. 354-362
    • Von Seggern, D.J.1    Huang, S.2    Fleck, S.K.3    Stevenson, S.C.4    Nemerow, G.R.5
  • 9
    • 0035915989 scopus 로고    scopus 로고
    • A 50-kDa membrane protein mediates sialic acid-independent binding and infection of conjunctival cells by adenovirus type 37
    • Wu E, Fernandez J, Fleck SK, Von Seggern DJ, Huang S, Nemerow GR: A 50-kDa membrane protein mediates sialic acid-independent binding and infection of conjunctival cells by adenovirus type 37. Virology (2001) 279(1):78-89.
    • (2001) Virology , vol.279 , Issue.1 , pp. 78-89
    • Wu, E.1    Fernandez, J.2    Fleck, S.K.3    Von Seggern, D.J.4    Huang, S.5    Nemerow, G.R.6
  • 10
    • 0343026622 scopus 로고    scopus 로고
    • Structural analysis of a fiber-pseudotyped adenovirus with ocular tropism suggests differential modes of cell receptor interactions
    • Chiu CY, Wu E, Brown SL, Von Seggern DJ, Nemerow GR, Stewart PL: Structural analysis of a fiber-pseudotyped adenovirus with ocular tropism suggests differential modes of cell receptor interactions. J Virol (2001) 75(11):5375-5380.
    • (2001) J. Virol. , vol.75 , Issue.11 , pp. 5375-5380
    • Chiu, C.Y.1    Wu, E.2    Brown, S.L.3    Von Seggern, D.J.4    Nemerow, G.R.5    Stewart, P.L.6
  • 13
    • 0035871784 scopus 로고    scopus 로고
    • Highly efficient transduction of human monocyte-derived dendritic cells with subgroup B fiber-modified adenovirus vectors enhances transgene-encoded antigen presentation to cytotoxic T cells
    • Rea D, Havenga MJ, van Den Assem M, Sutmuller RP, Lemckert A, Hoeben RC, Bout A, Melief CJ, Offringa R: Highly efficient transduction of human monocyte-derived dendritic cells with subgroup B fiber-modified adenovirus vectors enhances transgene-encoded antigen presentation to cytotoxic T cells. J Immunol (2001) 166(8):5236-5244.
    • (2001) J. Immunol. , vol.166 , Issue.8 , pp. 5236-5244
    • Rea, D.1    Havenga, M.J.2    van Den Assem, M.3    Sutmuller, R.P.4    Lemckert, A.5    Hoeben, R.C.6    Bout, A.7    Melief, C.J.8    Offringa, R.9
  • 14
    • 0034006112 scopus 로고    scopus 로고
    • Efficient gene transfer into human CD34+ cells by a retargeted adenovirus vector
    • Shayakhmetov DM, Papayannopoulou T, Stamatoyannopoulos G, Lieber A: Efficient gene transfer into human CD34+ cells by a retargeted adenovirus vector. J Virol (2000) 74(6):2567-2583.
    • (2000) J. Virol. , vol.74 , Issue.6 , pp. 2567-2583
    • Shayakhmetov, D.M.1    Papayannopoulou, T.2    Stamatoyannopoulos, G.3    Lieber, A.4
  • 17
    • 0036172153 scopus 로고    scopus 로고
    • Targeting of adenovirus vectors to tumor cells does not enable efficient transduction of breast cancer metastases
    • Shayakhmetov DM, Li ZY, Ni S, Lieber A: Targeting of adenovirus vectors to tumor cells does not enable efficient transduction of breast cancer metastases. Cancer Res (2002) 62(4):1063-1068.
    • (2002) Cancer Res. , vol.62 , Issue.4 , pp. 1063-1068
    • Shayakhmetov, D.M.1    Li, Z.Y.2    Ni, S.3    Lieber, A.4
  • 18
    • 0033988228 scopus 로고    scopus 로고
    • Adenovirus type 37 uses sialic acid as a cellular receptor
    • Arnberg N, Edlund K, Kidd AH, Wadell G: Adenovirus type 37 uses sialic acid as a cellular receptor. J Virol (2000) 74(1):42-48.
    • (2000) J. Virol. , vol.74 , Issue.1 , pp. 42-48
    • Arnberg, N.1    Edlund, K.2    Kidd, A.H.3    Wadell, G.4
  • 19
    • 0033755728 scopus 로고    scopus 로고
    • Dependence of adenovirus infectivity on length of the fiber shaft domain
    • Shayakhmetov DM, Lieber A: Dependence of adenovirus infectivity on length of the fiber shaft domain. J Virol (2000) 74(22):10274-10286.
    • (2000) J. Virol. , vol.74 , Issue.22 , pp. 10274-10286
    • Shayakhmetov, D.M.1    Lieber, A.2
  • 21
    • 77953082198 scopus 로고    scopus 로고
    • Fibroblast growth factor 2-retargeted adenoviral vectors exhibit a modified biolocalization pattern and display reduced toxicity relative to native adenoviral vectors
    • Printz MA, Gonzalez AM, Cunningham M, Gu DL, Ong M, Pierce GF, Aukerman SL: Fibroblast growth factor 2-retargeted adenoviral vectors exhibit a modified biolocalization pattern and display reduced toxicity relative to native adenoviral vectors. Hum Gene Ther (2000) 11(1):191-204.
    • (2000) Hum. Gene Ther. , vol.11 , Issue.1 , pp. 191-204
    • Printz, M.A.1    Gonzalez, A.M.2    Cunningham, M.3    Gu, D.L.4    Ong, M.5    Pierce, G.F.6    Aukerman, S.L.7
  • 22
    • 0034990347 scopus 로고    scopus 로고
    • Uptake of adenoviral vectors via fibroblast growth factor receptors involves intracellular pathways that differ from the targeting ligand
    • Hoganson DK, Sosnowski BA, Pierce GF, Doukas J: Uptake of adenoviral vectors via fibroblast growth factor receptors involves intracellular pathways that differ from the targeting ligand. Mol Ther (2001) 3(1):105-112.
    • (2001) Mol. Ther. , vol.3 , Issue.1 , pp. 105-112
    • Hoganson, D.K.1    Sosnowski, B.A.2    Pierce, G.F.3    Doukas, J.4
  • 24
    • 0037081279 scopus 로고    scopus 로고
    • Adenovirus targeting to c-erbB-2 oncoprotein by single-chain antibody fused to trimeric form of adenovirus receptor ectodomain
    • Kashentseva EA, Seki T, Curiel DT, Dmitriev IP: Adenovirus targeting to c-erbB-2 oncoprotein by single-chain antibody fused to trimeric form of adenovirus receptor ectodomain. Cancer Res (2002) 62(2):609-616.
    • (2002) Cancer Res. , vol.62 , Issue.2 , pp. 609-616
    • Kashentseva, E.A.1    Seki, T.2    Curiel, D.T.3    Dmitriev, I.P.4
  • 25
    • 0036146390 scopus 로고    scopus 로고
    • Targeting adenoviral vectors by using the extracellular domain of the coxsackie-adenovirus receptor: Improved potency via trimerization
    • Kim J, Smith T, Idamakanti N, Mulgrew K, Kaloss M, Kylefjord H, Ryan PC, Kaleko M, Stevenson SC: Targeting adenoviral vectors by using the extracellular domain of the coxsackie-adenovirus receptor: Improved potency via trimerization. J Virol (2002) 76(4):1892-1903.
    • (2002) J. Virol. , vol.76 , Issue.4 , pp. 1892-1903
    • Kim, J.1    Smith, T.2    Idamakanti, N.3    Mulgrew, K.4    Kaloss, M.5    Kylefjord, H.6    Ryan, P.C.7    Kaleko, M.8    Stevenson, S.C.9
  • 26
    • 0035418580 scopus 로고    scopus 로고
    • Targeting oncolytic adenoviral agents to the epidermal growth factor pathway with a secretory fusion molecule
    • Hemminki A, Dmitriev I, Liu B, Desmond RA, Alemany R, Curiel DT: Targeting oncolytic adenoviral agents to the epidermal growth factor pathway with a secretory fusion molecule. Cancer Res (2001) 61(17):6377-6381.
    • (2001) Cancer Res. , vol.61 , Issue.17 , pp. 6377-6381
    • Hemminki, A.1    Dmitriev, I.2    Liu, B.3    Desmond, R.A.4    Alemany, R.5    Curiel, D.T.6
  • 27
    • 0035158631 scopus 로고    scopus 로고
    • Reducing the native tropism of adenovirus vectors requires removal of both CAR and integrin interactions
    • Einfeld DA, Schroeder R, Roelvink PW, Lizonova A, King CR, Kovesdi I, Wickham TJ: Reducing the native tropism of adenovirus vectors requires removal of both CAR and integrin interactions. J Virol (2001) 75(23):11284-11291.
    • (2001) J. Virol. , vol.75 , Issue.23 , pp. 11284-11291
    • Einfeld, D.A.1    Schroeder, R.2    Roelvink, P.W.3    Lizonova, A.4    King, C.R.5    Kovesdi, I.6    Wickham, T.J.7
  • 29
    • 0033925797 scopus 로고    scopus 로고
    • Ectodomain of coxsackievirus and adenovirus receptor genetically fused to epidermal growth factor mediates adenovirus targeting to epidermal growth factor receptor-positive cells
    • Dmitriev I, Kashentseva E, Rogers BE, Krasnykh V, Curiel DT: Ectodomain of coxsackievirus and adenovirus receptor genetically fused to epidermal growth factor mediates adenovirus targeting to epidermal growth factor receptor-positive cells. J Virol (2000) 74(15):6875-6884.
    • (2000) J. Virol. , vol.74 , Issue.15 , pp. 6875-6884
    • Dmitriev, I.1    Kashentseva, E.2    Rogers, B.E.3    Krasnykh, V.4    Curiel, D.T.5
  • 30
    • 0033230520 scopus 로고    scopus 로고
    • Modification of an adenoviral vector with biologically selected peptides: A novel strategy for gene delivery to cells of choice
    • Romanczuk H, Galer CE, Zabner J, Barsomian G, Wadsworth SC, O'Riordan CR: Modification of an adenoviral vector with biologically selected peptides: A novel strategy for gene delivery to cells of choice. Hum Gene Ther (1999) 10(16):2615-2626.
    • (1999) Hum. Gene Ther. , vol.10 , Issue.16 , pp. 2615-2626
    • Romanczuk, H.1    Galer, C.E.2    Zabner, J.3    Barsomian, G.4    Wadsworth, S.C.5    O'Riordan, C.R.6
  • 32
    • 0035077806 scopus 로고    scopus 로고
    • Polymer-coated adenovirus permits efficient retargeting and evades neutralising antibodies
    • Fisher KD, Stallwood Y, Green NK, Ulbrich K, Mautner V, Seymour LW: Polymer-coated adenovirus permits efficient retargeting and evades neutralising antibodies. Gene Ther (2001) 8(5):341-348.
    • (2001) Gene Ther. , vol.8 , Issue.5 , pp. 341-348
    • Fisher, K.D.1    Stallwood, Y.2    Green, N.K.3    Ulbrich, K.4    Mautner, V.5    Seymour, L.W.6
  • 33
    • 0034632396 scopus 로고    scopus 로고
    • Development of a rapid method for the PEGylation of adenoviruses with enhanced transduction and improved stability under harsh storage conditions
    • Croyle MA, Yu QC, Wilson JM: Development of a rapid method for the PEGylation of adenoviruses with enhanced transduction and improved stability under harsh storage conditions. Hum Gene Ther (2000) 11(12):1713-1722.
    • (2000) Hum. Gene Ther. , vol.11 , Issue.12 , pp. 1713-1722
    • Croyle, M.A.1    Yu, Q.C.2    Wilson, J.M.3
  • 34
    • 0030940283 scopus 로고    scopus 로고
    • v Integrins as receptors for tumor targeting by circulating ligands
    • v Integrins as receptors for tumor targeting by circulating ligands. Nat Biotechnol (1997) 15(6):542-546.
    • (1997) Nat. Biotechnol. , vol.15 , Issue.6 , pp. 542-546
    • Pasqualini, R.1    Koivunen, E.2    Ruoslahti, E.3
  • 35
    • 0029858682 scopus 로고    scopus 로고
    • Adenovirus targeted to heparan-containing receptors increases its gene delivery efficiency to multiple cell types
    • Wickham TJ, Roelvink PW, Brough DE, Kovesdi I: Adenovirus targeted to heparan-containing receptors increases its gene delivery efficiency to multiple cell types. Nat Biotechnol (1996) 14(11):1570-1573.
    • (1996) Nat. Biotechnol. , vol.14 , Issue.11 , pp. 1570-1573
    • Wickham, T.J.1    Roelvink, P.W.2    Brough, D.E.3    Kovesdi, I.4
  • 36
    • 0034985866 scopus 로고    scopus 로고
    • A simplified system for constructing recombinant adenoviral vectors containing heterologous peptides in the HI loop of their fiber knob
    • Mizuguchi H, Koizumi N, Hosono T, Utoguchi N, Watanabe Y, Kay MA, Hayakawa T: A simplified system for constructing recombinant adenoviral vectors containing heterologous peptides in the HI loop of their fiber knob. Gene Ther (2001) 8(9):730-735.
    • (2001) Gene Ther. , vol.8 , Issue.9 , pp. 730-735
    • Mizuguchi, H.1    Koizumi, N.2    Hosono, T.3    Utoguchi, N.4    Watanabe, Y.5    Kay, M.A.6    Hayakawa, T.7
  • 37
    • 0036200923 scopus 로고    scopus 로고
    • Enhanced antitumor effect and reduced vector dissemination with fiber-modified adenovirus vectors expressing herpes simplex virus thymidine kinase
    • Mizuguchi H, Hayakawa T: Enhanced antitumor effect and reduced vector dissemination with fiber-modified adenovirus vectors expressing herpes simplex virus thymidine kinase. Cancer Gene Ther (2002) 9(3):236-242.
    • (2002) Cancer Gene Ther. , vol.9 , Issue.3 , pp. 236-242
    • Mizuguchi, H.1    Hayakawa, T.2
  • 38
    • 0036202814 scopus 로고    scopus 로고
    • Effective gene transfer to human melanomas via integrin-targeted adenoviral vectors
    • Nakamura T, Sato K, Hamada H: Effective gene transfer to human melanomas via integrin-targeted adenoviral vectors. Hum Gene Ther (2002) 13(5):613-626.
    • (2002) Hum. Gene Ther. , vol.13 , Issue.5 , pp. 613-626
    • Nakamura, T.1    Sato, K.2    Hamada, H.3
  • 39
    • 0034467640 scopus 로고    scopus 로고
    • Recombinant human adenovirus: Targeting to the human transferrin receptor improves gene transfer to brain microcapillary endothelium
    • Xia H, Anderson B, Mao Q, Davidson BL: Recombinant human adenovirus: Targeting to the human transferrin receptor improves gene transfer to brain microcapillary endothelium. J Virol (2000) 74(23):11359-11366.
    • (2000) J. Virol. , vol.74 , Issue.23 , pp. 11359-11366
    • Xia, H.1    Anderson, B.2    Mao, Q.3    Davidson, B.L.4
  • 40
    • 0035661202 scopus 로고    scopus 로고
    • Ablating adenovirus type 5 fiber-CAR binding and HI loop insertion of the SIGYPLP peptide generate an endothelial cell-selective adenovirus
    • Nicklin SA, Von Seggern DJ, Work LM, Pek DC, Dominiczak AF, Nemerow GR, Baker AH: Ablating adenovirus type 5 fiber-CAR binding and HI loop insertion of the SIGYPLP peptide generate an endothelial cell-selective adenovirus. Mol Ther (2001) 4(6):534-542.
    • (2001) Mol. Ther. , vol.4 , Issue.6 , pp. 534-542
    • Nicklin, S.A.1    Von Seggern, D.J.2    Work, L.M.3    Pek, D.C.4    Dominiczak, A.F.5    Nemerow, G.R.6    Baker, A.H.7
  • 41
    • 0034948066 scopus 로고    scopus 로고
    • Phage display of adenovirus type 5 fiber knob as a tool for specific ligand selection and validation
    • Pereboev A, Pereboeva L, Curiel DT: Phage display of adenovirus type 5 fiber knob as a tool for specific ligand selection and validation. J Virol (2001) 75(15):7107-7113.
    • (2001) J. Virol. , vol.75 , Issue.15 , pp. 7107-7113
    • Pereboev, A.1    Pereboeva, L.2    Curiel, D.T.3
  • 44
    • 0034899517 scopus 로고    scopus 로고
    • Genetic retargeting of adenovirus: Novel strategy employing "deknobbing" of the fiber
    • Magnusson MK, Hong SS, Boulanger P, Lindholm L: Genetic retargeting of adenovirus: Novel strategy employing "deknobbing" of the fiber. J Virol (2001) 75(16):7280-7289.
    • (2001) J. Virol. , vol.75 , Issue.16 , pp. 7280-7289
    • Magnusson, M.K.1    Hong, S.S.2    Boulanger, P.3    Lindholm, L.4
  • 45
    • 0035043341 scopus 로고    scopus 로고
    • Genetic targeting of an adenovirus vector via replacement of the fiber protein with the phage T4 fibritin
    • Krasnykh V, Belousova N, Korokhov N, Mikheeva G, Curiel DT: Genetic targeting of an adenovirus vector via replacement of the fiber protein with the phage T4 fibritin. J Virol (2001) 75(9):4176-4183.
    • (2001) J. Virol. , vol.75 , Issue.9 , pp. 4176-4183
    • Krasnykh, V.1    Belousova, N.2    Korokhov, N.3    Mikheeva, G.4    Curiel, D.T.5
  • 46
    • 0033039503 scopus 로고    scopus 로고
    • Fiber swap between adenovirus subgroups B and C alters intracellular trafficking of adenovirus gene transfer vectors
    • Miyazawa N, Leopold PL, Hackett NR, Ferris B, Worgall S, Falck-Pedersen E, Crystal RG: Fiber swap between adenovirus subgroups B and C alters intracellular trafficking of adenovirus gene transfer vectors. J Virol (1999) 73(7):6056-6065.
    • (1999) J. Virol. , vol.73 , Issue.7 , pp. 6056-6065
    • Miyazawa, N.1    Leopold, P.L.2    Hackett, N.R.3    Ferris, B.4    Worgall, S.5    Falck-Pedersen, E.6    Crystal, R.G.7
  • 47
    • 0035154757 scopus 로고    scopus 로고
    • Adenovirus serotype 7 retention in a late endosomal compartment prior to cytosol escape is modulated by fiber protein
    • Miyazawa N, Crystal RG, Leopold PL: Adenovirus serotype 7 retention in a late endosomal compartment prior to cytosol escape is modulated by fiber protein. J Virol (2001) 75(3):1387-1400.
    • (2001) J. Virol. , vol.75 , Issue.3 , pp. 1387-1400
    • Miyazawa, N.1    Crystal, R.G.2    Leopold, P.L.3
  • 48
    • 0034830243 scopus 로고    scopus 로고
    • CAR-binding ablation does not change biodistribution and toxicity of adenoviral vectors
    • Alemany R, Curiel DT: CAR-binding ablation does not change biodistribution and toxicity of adenoviral vectors. Gene Ther (2001) 8(17):1347-1353.
    • (2001) Gene Ther. , vol.8 , Issue.17 , pp. 1347-1353
    • Alemany, R.1    Curiel, D.T.2
  • 52
    • 0034044848 scopus 로고    scopus 로고
    • Retargeting the coxsackievirus and adenovirus receptor to the apical surface of polarized epithelial cells reveals the glycocalyx as a barrier to adenovirus-mediated gene transfer
    • Pickles RJ, Fahrner JA, Petrella JM, Boucher RC, Bergelson JM: Retargeting the coxsackievirus and adenovirus receptor to the apical surface of polarized epithelial cells reveals the glycocalyx as a barrier to adenovirus-mediated gene transfer. J Virol (2000) 74(13):6050-6057.
    • (2000) J. Virol. , vol.74 , Issue.13 , pp. 6050-6057
    • Pickles, R.J.1    Fahrner, J.A.2    Petrella, J.M.3    Boucher, R.C.4    Bergelson, J.M.5
  • 53
    • 0031034030 scopus 로고    scopus 로고
    • Innate immune mechanisms dominate elimination of adenoviral vectors following in vivo administration
    • Worgall S, Wolff G, Falck-Pedersen E, Crystal RG: Innate immune mechanisms dominate elimination of adenoviral vectors following in vivo administration. Hum Gene Ther (1997) 8(1):37-44.
    • (1997) Hum. Gene Ther. , vol.8 , Issue.1 , pp. 37-44
    • Worgall, S.1    Wolff, G.2    Falck-Pedersen, E.3    Crystal, R.G.4
  • 54
    • 0034980914 scopus 로고    scopus 로고
    • Sequestration of adenoviral vector by Kupffer cells leads to a nonlinear dose response of transduction in liver
    • Tao N, Gao GP, Parr M, Johnston J, Baradet T, Wilson JM, Barsoum J, Fawell SE: Sequestration of adenoviral vector by Kupffer cells leads to a nonlinear dose response of transduction in liver. Mol Ther (2001) 3(1):28-35.
    • (2001) Mol. Ther. , vol.3 , Issue.1 , pp. 28-35
    • Tao, N.1    Gao, G.P.2    Parr, M.3    Johnston, J.4    Baradet, T.5    Wilson, J.M.6    Barsoum, J.7    Fawell, S.E.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.