Influence of the structural diversity of data sets on the statistical quality of three-dimensional quantitative structure - Activity relationship (3D-QSAR) models: Predicting the estrogenic activity of xenoestrogens

Chemical Research in Toxicology

Volumn 15, Issue 10, 2002, Pages 1229-1234

  Yu, Seong Jae ^a   Keenan, Susan M ^a   Tong, Weida ^b   Welsh, William J ^a  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,1 DICHLORO 2,2 BIS(4 CHLOROPHENYL)ETHYLENE; 4 HYDROXYTAMOXIFEN; 4 TERT OCTYLPHENOL; 4,4' ISOPROPYLIDENEDIPHENOL; ALKYLPHENOL; ANTIESTROGEN; CHLORPHENOTANE; COUMESTROL; DAIDZEIN; DIENESTROL; DIETHYLSTILBESTROL; EQUOL; ESTRADIOL; ESTROGEN; FORMONONETIN; GENISTEIN; HEXESTROL; HYDROXYBIPHENYL; LACTONE; MESTRANOL; ORGANOCHLORINE DERIVATIVE; PHENOL DERIVATIVE; PHTHALIC ACID DERIVATIVE; PHYTOESTROGEN; STEROID; TAMOXIFEN; UNCLASSIFIED DRUG; UNINDEXED DRUG; XENOESTROGEN; ZEARALENONE; ZERANOL;

ARTICLE; COMPUTER MODEL; DRUG POTENCY; ENDOCRINE SYSTEM; ESTROGEN ACTIVITY; MOLECULAR MODEL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RISK ASSESSMENT;

ANIMALS; DATA INTERPRETATION, STATISTICAL; ENDOCRINE SYSTEM; ESTROGENS; FORECASTING; HUMANS; MODELS, CHEMICAL; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; STRUCTURE-ACTIVITY RELATIONSHIP; XENOBIOTICS;

EID: 0036802392     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx0255875     Document Type: Article

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