Pregnenolone stimulates LNCaP prostate cancer cell growth via the mutated androgen receptor

Journal of Steroid Biochemistry and Molecular Biology

Volumn 75, Issue 1, 2000, Pages 1-10

  Grigoryev, Dmitry N ^a   Long, Brian J ^a   Njar, Vincent C O ^a   Brodie, Angela H M ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Androgen receptor; Growth inhibition; LNCaP prostate cancer cell line; Novel androgen synthesis inhibitors; Pregnenolone

Indexed keywords

ANDROGEN; ANDROGEN RECEPTOR; ANDROSTANOLONE; ANTIESTROGEN; ANTIGESTAGEN; DRUG METABOLITE; PREGNENOLONE; PREGNENOLONE METABOLITE; UNCLASSIFIED DRUG;

ANDROGEN SYNTHESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING SITE; CANCER CELL CULTURE; CANCER GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; DRUG BLOOD LEVEL; GENETIC TRANSCRIPTION; GROWTH STIMULATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; INCUBATION TIME; MALE; MOUSE; NONHUMAN; PROSTATE CARCINOMA; RECEPTOR BINDING; SCID MOUSE;

ANIMALS; BINDING, COMPETITIVE; CELL DIVISION; CELL LINE; DEXAMETHASONE; DIHYDROTESTOSTERONE; GENE EXPRESSION REGULATION; HUMANS; MALE; MICE; MICE, SCID; MUTATION; NEOPLASM TRANSPLANTATION; PREGNENOLONE; PROSTATIC NEOPLASMS; RECEPTORS, ANDROGEN; STEROIDS; TRANSFECTION; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 0034484856     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-0760(00)00131-X     Document Type: Article

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