-
1
-
-
0030694234
-
The emerging role of CTLA-4 as an immune attenuator
-
Thompson, C. B., and J. P. Allison. 1997. The emerging role of CTLA-4 as an immune attenuator. Immunity 7:445.
-
(1997)
Immunity
, vol.7
, pp. 445
-
-
Thompson, C.B.1
Allison, J.P.2
-
3
-
-
0030176384
-
Upstream-downstream: CD28 cosignaling pathways and T cell function
-
Rudd, C. E. 1996. Upstream-downstream: CD28 cosignaling pathways and T cell function. Immunity 4:527.
-
(1996)
Immunity
, vol.4
, pp. 527
-
-
Rudd, C.E.1
-
4
-
-
0033971597
-
Structure and dimerization of a soluble form of B7-1
-
Ikemizu, S., R. J. C. Gilbert, J. A. Fennelly, A. V. Collins, K. Harlos, E. Y. Jones, D. I. Stuart, and S. J. Davis. 2000. Structure and dimerization of a soluble form of B7-1. Immunity 12:51.
-
(2000)
Immunity
, vol.12
, pp. 51
-
-
Ikemizu, S.1
Gilbert, R.J.C.2
Fennelly, J.A.3
Collins, A.V.4
Harlos, K.5
Jones, E.Y.6
Stuart, D.I.7
Davis, S.J.8
-
5
-
-
0028484545
-
CTLA-4 can function as a negative regulator of T cell activation
-
Walunas, T. L., D. J. Lenschow, C. Y. Bakker, P. S. Linsley, G. J. Freeman, J. M. Green, C. B. Thompson, and J. A. Bluestone. 1994. CTLA-4 can function as a negative regulator of T cell activation. Immunity 1:405.
-
(1994)
Immunity
, vol.1
, pp. 405
-
-
Walunas, T.L.1
Lenschow, D.J.2
Bakker, C.Y.3
Linsley, P.S.4
Freeman, G.J.5
Green, J.M.6
Thompson, C.B.7
Bluestone, J.A.8
-
6
-
-
0029120245
-
CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation
-
Krummel, M. F., and J. P. Allison. 1995. CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation. J. Exp. Med. 182:459.
-
(1995)
J. Exp. Med.
, vol.182
, pp. 459
-
-
Krummel, M.F.1
Allison, J.P.2
-
7
-
-
0028867420
-
Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
-
Tivol, E. A., F. Borriello, A. N. Schweitzer, W. P. Lynch, J. A. Bluestone, and A. H. Sharpe. 1995. Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. Immunity 3:541.
-
(1995)
Immunity
, vol.3
, pp. 541
-
-
Tivol, E.A.1
Borriello, F.2
Schweitzer, A.N.3
Lynch, W.P.4
Bluestone, J.A.5
Sharpe, A.H.6
-
8
-
-
0028791059
-
Lymphoproliferative disorders with early lethality in mice deficient in CTLA-4
-
Waterhouse, P., J. M. Penninger, E. Timms, A. Wakeham, A. Shahinian, K. P. Lee, C. B. Thompson, H. Griesser, and T. W. Mak. 1995. Lymphoproliferative disorders with early lethality in mice deficient in CTLA-4. Science 270: 985.
-
(1995)
Science
, vol.270
, pp. 985
-
-
Waterhouse, P.1
Penninger, J.M.2
Timms, E.3
Wakeham, A.4
Shahinian, A.5
Lee, K.P.6
Thompson, C.B.7
Griesser, H.8
Mak, T.W.9
-
9
-
-
0034176009
-
+ T cells toward the Th1 subset by CTLA-4 costimulation
-
+ T cells toward the Th1 subset by CTLA-4 costimulation. J. Immunol. 164:3554.
-
(2000)
J. Immunol.
, vol.164
, pp. 3554
-
-
Kato, T.1
Nariuchi, H.2
-
11
-
-
0035554676
-
Regulatory T cells in the control of immune pathology
-
Maloy, K. J., and F. Powrie. 2001. Regulatory T cells in the control of immune pathology. Nat. Immunol. 2:816.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 816
-
-
Maloy, K.J.1
Powrie, F.2
-
12
-
-
0034651999
-
TGF-β mediates CTLA-4 suppression of cellular immunity in murine Kalaazar
-
Gomes, N. A., C. R. Gattass, V. Barreto-de-Souza, M. E. Wilson, and G. A. DosReis. 2000. TGF-β mediates CTLA-4 suppression of cellular immunity in murine Kalaazar. J. Immunol. 164:2001.
-
(2000)
J. Immunol.
, vol.164
, pp. 2001
-
-
Gomes, N.A.1
Gattass, C.R.2
Barreto-de-Souza, V.3
Wilson, M.E.4
DosReis, G.A.5
-
14
-
-
0028910221
-
CTLA-4 binding to the lipid kinase phosphatidylinositol 3-kinase in T cells
-
Schneider, H., K. V. S. Prasad, S. E. Shoelson, and C. E. Rudd. 1995. CTLA-4 binding to the lipid kinase phosphatidylinositol 3-kinase in T cells. J. Exp. Med 181:351.
-
(1995)
J. Exp. Med.
, vol.181
, pp. 351
-
-
Schneider, H.1
Prasad, K.V.S.2
Shoelson, S.E.3
Rudd, C.E.4
-
15
-
-
0032545452
-
Molecular basis of T cell inactivation by CTLA-4
-
Lee, K. M., E. Chuang, M. Griffin, R. Khattri, D. K. Hong, W. Zhang, D. Straus, L. E. Samelson, C. B. Thompson, and J. A. Bluestone. 1998. Molecular basis of T cell inactivation by CTLA-4. Science 282:2263.
-
(1998)
Science
, vol.282
, pp. 2263
-
-
Lee, K.M.1
Chuang, E.2
Griffin, M.3
Khattri, R.4
Hong, D.K.5
Zhang, W.6
Straus, D.7
Samelson, L.E.8
Thompson, C.B.9
Bluestone, J.A.10
-
16
-
-
0030001318
-
Regulation of T cell receptor signaling by tyrosine phosphatase Syp association with CTLA-4
-
Marengère, L. E. M., P. Waterhouse, G. S. Duncan, H.-W. Mittrücker, G.-S. Feng, and T. W. Mak. 1996. Regulation of T cell receptor signaling by tyrosine phosphatase Syp association with CTLA-4. Science 272:1170.
-
(1996)
Science
, vol.272
, pp. 1170
-
-
Marengère, L.E.M.1
Waterhouse, P.2
Duncan, G.S.3
Mittrücker, H.-W.4
Feng, G.-S.5
Mak, T.W.6
-
17
-
-
0033662376
-
The CD28 and CTLA-4 receptors associate with the serine/threonine phosphatase PP2A
-
Chuang, E., T. S. Fisher, R. W. Morgan, M. D. Robbins, M. G. Duerr, J. P. Vander Heiden, J. E. Gardner, and M. J. Hambor. 2000. The CD28 and CTLA-4 receptors associate with the serine/threonine phosphatase PP2A. Immunity 13:313.
-
(2000)
Immunity
, vol.13
, pp. 313
-
-
Chuang, E.1
Fisher, T.S.2
Morgan, R.W.3
Robbins, M.D.4
Duerr, M.G.5
Vander Heiden, J.P.6
Gardner, J.E.7
Hambor, M.J.8
-
18
-
-
0030707866
-
2-terminal kinase (JNK) activation, but does not affect phosphorylation of T cell receptor ζ and ZAP70
-
2-terminal kinase (JNK) activation, but does not affect phosphorylation of T cell receptor ζ and ZAP70. J. Exp. Med. 186:1645.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 1645
-
-
Calvo, C.R.1
Amsem, D.2
Kruisbeek, A.M.3
-
19
-
-
0035803552
-
Cytotoxic T lymphocyte antigen 4 potently inhibits cell surface raft expression in its regulation of T cell function
-
Martin, M., H. Schneider, A. Azouz, and C. E. Rudd. 2001. Cytotoxic T lymphocyte antigen 4 potently inhibits cell surface raft expression in its regulation of T cell function. J. Exp. Med. 194:1675.
-
(2001)
J. Exp. Med.
, vol.194
, pp. 1675
-
-
Martin, M.1
Schneider, H.2
Azouz, A.3
Rudd, C.E.4
-
20
-
-
0037117823
-
CTLA-4 negative signaling via lipid rafts: A new perspective
-
Rudd, C. E., M. Martin, and H. Schneider. 2002. CTLA-4 negative signaling via lipid rafts: a new perspective. Sci. STKE. 128:PE18.
-
(2002)
Sci. STKE
, vol.128
-
-
Rudd, C.E.1
Martin, M.2
Schneider, H.3
-
21
-
-
0033579816
-
B7-1 or B7-2 is required to produce the lymphoproliferative phenotype in mice lacking cytotoxic T lymphocyte-associated antigen 4 (CTLA-4)
-
Mandelbrot, D. A., A. J. McAdam, and A. H. Sharpe. 1999. B7-1 or B7-2 is required to produce the lymphoproliferative phenotype in mice lacking cytotoxic T lymphocyte-associated antigen 4 (CTLA-4). J. Exp. Med. 189:435.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 435
-
-
Mandelbrot, D.A.1
McAdam, A.J.2
Sharpe, A.H.3
-
22
-
-
0030936275
-
B7-1 and B7-2 have overlapping, critical roles in immunoglobulin class switching and germinal center formation
-
Borriello, F., M. P. Sethna, S. D. Boyd, A. N. Schweitzer, E. A. Tivol, D. Jacoby, T. B. Strom, E. M. Simpson, G. J. Freeman, and A. H. Sharpe. 1997. B7-1 and B7-2 have overlapping, critical roles in immunoglobulin class switching and germinal center formation. Immunity 6:303.
-
(1997)
Immunity
, vol.6
, pp. 303
-
-
Borriello, F.1
Sethna, M.P.2
Boyd, S.D.3
Schweitzer, A.N.4
Tivol, E.A.5
Jacoby, D.6
Strom, T.B.7
Simpson, E.M.8
Freeman, G.J.9
Sharpe, A.H.10
-
23
-
-
0033567050
-
Cytolytic T lymphocyte-associated antigen-4 and the TCRζ/CD3 complex, but not CD28, interact with clathrin adaptor complexes AP-1 and AP-2
-
Schneider, H., M. Martin, F. A. Agarraberes, L. Yin, I. Rapoport, T. Kirchhausen, and C. E. Rudd. 1999. Cytolytic T lymphocyte-associated antigen-4 and the TCRζ/CD3 complex, but not CD28, interact with clathrin adaptor complexes AP-1 and AP-2. J. Immunol. 163:1868.
-
(1999)
J. Immunol.
, vol.163
, pp. 1868
-
-
Schneider, H.1
Martin, M.2
Agarraberes, F.A.3
Yin, L.4
Rapoport, I.5
Kirchhausen, T.6
Rudd, C.E.7
-
24
-
-
0034644522
-
Signal transduction by the JNK group of MAP kinases
-
Davis, R. J. 2000. Signal transduction by the JNK group of MAP kinases. Cell 103:239.
-
(2000)
Cell
, vol.103
, pp. 239
-
-
Davis, R.J.1
-
25
-
-
0028291525
-
JNK is involved in signal integration during costimulation of T lymphocytes
-
Su, B., E. Jacinto, M. Hibi, T. Kullunki, M. Karin, and Y. Ben-Neriah. 1994. JNK is involved in signal integration during costimulation of T lymphocytes. Cell 77:727.
-
(1994)
Cell
, vol.77
, pp. 727
-
-
Su, B.1
Jacinto, E.2
Hibi, M.3
Kullunki, T.4
Karin, M.5
Ben-Neriah, Y.6
-
26
-
-
0031962106
-
Growth factor receptor-bound protein 2 SH2/SH3 domain binding to CD28 and its role in co-signaling
-
Kim, H.-H., M. Tharayil, and C. E. Rudd. 1998. Growth factor receptor-bound protein 2 SH2/SH3 domain binding to CD28 and its role in co-signaling. J. Biol. Chem. 273:296.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 296
-
-
Kim, H.-H.1
Tharayil, M.2
Rudd, C.E.3
-
27
-
-
0030740248
-
Thymic development is normal in CTLA-4-deficient mice
-
Chambers, C. A., D. Cado, T. Truong, and J. P. Allison. 1997. Thymic development is normal in CTLA-4-deficient mice. Proc. Natl. Acad. Sci. USA 94:9296.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 9296
-
-
Chambers, C.A.1
Cado, D.2
Truong, T.3
Allison, J.P.4
-
28
-
-
0030740572
-
Normal thymic selection, normal viability and decreased lymphoproliferation in T cell receptor-transgenic CTLA-4-deficient mice
-
Waterhouse, P., M. F. Bachmann, J. M. Penninger, P. S. Ohashi, and T. W. Mak. 1997. Normal thymic selection, normal viability and decreased lymphoproliferation in T cell receptor-transgenic CTLA-4-deficient mice. Eur. J. Immunol. 27: 1887.
-
(1997)
Eur. J. Immunol.
, vol.27
, pp. 1887
-
-
Waterhouse, P.1
Bachmann, M.F.2
Penninger, J.M.3
Ohashi, P.S.4
Mak, T.W.5
-
29
-
-
0033970117
-
CD69-triggered ERK activation and functions are negatively regulated by CD94/NKG2-A inhibitory receptor
-
Zingoni, A., G. Palmieri, S. Morrone, M. Carretero, M. Lopez-Botel, M. Piccoli, L. Frati, and A. Santoni. 2000. CD69-triggered ERK activation and functions are negatively regulated by CD94/NKG2-A inhibitory receptor. Eur. J. Immunol. 30:644.
-
(2000)
Eur. J. Immunol.
, vol.30
, pp. 644
-
-
Zingoni, A.1
Palmieri, G.2
Morrone, S.3
Carretero, M.4
Lopez-Botel, M.5
Piccoli, M.6
Frati, L.7
Santoni, A.8
-
30
-
-
0030966217
-
Induction of peripheral T cell tolerance in vivo requires CTLA-4 engagement
-
Perez, V. L., L. Van Parijs, A. Biuckians, X. X. Zheng, T. B. Strom, and A. K, Abbas. 1997, Induction of peripheral T cell tolerance in vivo requires CTLA-4 engagement. Immunity 6:411.
-
(1997)
Immunity
, vol.6
, pp. 411
-
-
Perez, V.L.1
Van Parijs, L.2
Biuckians, A.3
Zheng, X.X.4
Strom, T.B.5
Abbas, A.K.6
-
31
-
-
0035102196
-
CTLA-4 regulates induction of anergy in vivo
-
Greenwald, R. J., V. A. Boussiotis, R. B, Lorsbach, A. K. Abbas, and A. H. Sharpe. 2001. CTLA-4 regulates induction of anergy in vivo. Immunity 14:145.
-
(2001)
Immunity
, vol.14
, pp. 145
-
-
Greenwald, R.J.1
Boussiotis, V.A.2
Lorsbach, R.B.3
Abbas, A.K.4
Sharpe, A.H.5
-
35
-
-
0033198045
-
The role of CTLA-4 in regulating Th2 differentiation
-
Oosterwegel, M. A., D. A. Mandelbrot, S. D. Boyd, R. B. Lorsbach, D. Y. Jarrett, A. K. Abbas, and A. H. Sharpe. 1999. The role of CTLA-4 in regulating Th2 differentiation. J. Immunol. 163:2634.
-
(1999)
J. Immunol.
, vol.163
, pp. 2634
-
-
Oosterwegel, M.A.1
Mandelbrot, D.A.2
Boyd, S.D.3
Lorsbach, R.B.4
Jarrett, D.Y.5
Abbas, A.K.6
Sharpe, A.H.7
-
36
-
-
0028221022
-
T-cell antigen CD28 interacts with the lipid kinase phosphatidylinositol 3-kinase by a cytoplasmic Tyr(P)-Met-Xaa-Met motif
-
Prasad, K. V. S., Y.-C. Cai, M. Raab, B. Duckworth, L. Cantley, S. E. Shoelson, and C. E, Rudd. 1994. T-cell antigen CD28 interacts with the lipid kinase phosphatidylinositol 3-kinase by a cytoplasmic Tyr(P)-Met-Xaa-Met motif. Proc. Natl. Acad. Sci. USA 91:2834.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 2834
-
-
Prasad, K.V.S.1
Cai, Y.-C.2
Raab, M.3
Duckworth, B.4
Cantley, L.5
Shoelson, S.E.6
Rudd, C.E.7
-
37
-
-
0029931976
-
Two distinct intracytoplasmic regions of the T-cell adhesion molecule CD28 participate in phosphatidylinositol 3-kinase association
-
Pages, F., M. Ragueneau, S. Klasen, M. Battifora, D. Couez, R. Sweet, A. Truneh, S. G. Ward, and D. Olive. 1996. Two distinct intracytoplasmic regions of the T-cell adhesion molecule CD28 participate in phosphatidylinositol 3-kinase association. J. Biol. Chem. 271:9403.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 9403
-
-
Pages, F.1
Ragueneau, M.2
Klasen, S.3
Battifora, M.4
Couez, D.5
Sweet, R.6
Truneh, A.7
Ward, S.G.8
Olive, D.9
-
38
-
-
0031575749
-
Requirement of phosphatidylinositol-3 kinase for activation of JNK/SAPKs by PDGF
-
Lopez-Ilasaca, M., W. Li, A. Uren, J. C. Yu, A. Kazlauskas, J. S. Gutkind, and M. A. Heidaran. 1997. Requirement of phosphatidylinositol-3 kinase for activation of JNK/SAPKs by PDGF. Biochem. Biophys. Res. Commun. 232:273.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.232
, pp. 273
-
-
Lopez-Ilasaca, M.1
Li, W.2
Uren, A.3
Yu, J.C.4
Kazlauskas, A.5
Gutkind, J.S.6
Heidaran, M.A.7
-
39
-
-
0035366079
-
MAP-kinase signaling pathways in T cells
-
Rincon, M. 2001. MAP-kinase signaling pathways in T cells. Curr. Opin. Immunol. 13:339.
-
(2001)
Curr. Opin. Immunol.
, vol.13
, pp. 339
-
-
Rincon, M.1
|