Specificity of Distalless repression and limb primordia development by abdominal Hox proteins

Developmental Cell

Volumn 3, Issue 4, 2002, Pages 487-498

  Gebelein, Brian ^a   Culi, Joaquim ^a   Ryoo, Hyung Don ^a   Zhang, Wen ^a   Mann, Richard S ^a  

^a HHSC 1104 ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; HOMEODOMAIN PROTEIN; HOX PROTEIN; RNA; TRANSCRIPTION FACTOR;

ABDOMEN; ALTERNATIVE RNA SPLICING; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; DNA BINDING; DROSOPHILA; EMBRYO SEGMENTATION; GENE ACTIVATION; GENE REPRESSION; LEG; LIMB DEVELOPMENT; NONHUMAN; PROTEIN FUNCTION;

DROSOPHILA; VERTEBRATA;

EID: 0036774750     PISSN: 15345807     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1534-5807(02)00257-5     Document Type: Article

References (54)

1. Brand, A., and Perrimon, N. (1993). Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118, 401-415.
2. Busturia, A., Vernos, I., Macias, A., Casanova, J., and Morata, G. (1990). Different forms of Ultrabithorax proteins generated by alternative splicing are functionally equivalent. EMBO J. 9, 3551-3555.
3. Capovilla, M., Brandt, M., and Botas, J. (1994). Direct regulation of decapentaplegic by Ultrabithorax and its role in Drosophila midgut morphogenesis. Cell 76, 461-475.
4. Carroll, S.B. (1995). Homeotic genes and the evolution of arthropods and chordates. Nature 376, 479-485.
5. Casares, F., and Mann, R.S. (1998). Control of antennal versus leg development in Drosophila. Nature 392, 723-726.
6. Chan, S.-K., and Mann, R.S. (1993). The segment identity functions of Ultrabithorax are contained within its homeo domain and carboxyterminal sequences. Genes Dev. 7, 796-811.
7. Chan, S.-K., Ryoo, H.D., Gould, A., Krumlauf, R., and Mann, R. (1997). Switching the in vivo specificity of a minimal Hox-responsive element. Development 124, 2007-2014.
8. Chang, C.P., Brocchieri, L., Shen, W.F., Largman, C., and Cleary, M.L. (1996). Pbx modulation of Hox homeodomain amino-terminal arms establishes different DNA-binding specificities across the Hox locus. Mol. Cell. Biol. 16, 1734-1745.
9. Chauvet, S., Merabet, S., Bilder, D., Scott, M.P., Pradel, J., and Graba, Y. (2000). Distinct hox protein sequences determine specificity in different tissues. Proc. Natl. Acad. Sci. USA 97, 4064-4069.
10. Chung, Y.-T., and Keller, E.B. (1990). Positive and negative regulatory elements mediating transcription from the Drosophila melanogaster actin 5C distal promoter. Mol. Cell. Biol. 10, 6172-6180.
11. Condie, J.M., Mustard, J.A., and Brower, D. (1991). Generation of anti-Antennapedia monoclonal antibodies and Antennapedia protein expression in imaginal discs. Drosoph. Inf. Serv. 70, 52-54.
12. Ferretti, E., Marshall, H., Popperl, H., Maconochie, M., Krumlauf, R., and Blasi, F. (2000). Segmental expression of Hoxb2 in r4 requires two separate sites that integrate cooperative interactions between Prep1, Pbx and Hox proteins. Development 127, 155-166.
13. Florence, B., Guichet, A., Ephrussi, A., and Laughon, A. (1997). Ftz-F1 is a cofactor in Ftz activation of the Drosophila engrailed gene. Development 124, 839-847.
14. Furukubo-Tokunaga, K., Flister, S., and Gehring, W.J. (1993). Functional specificity of the Antennapedia homeodomain. Proc. Natl. Acad. Sci. USA 90, 6360-6364.
15. Galant, R., and Carroll, S.B. (2002). Evolution of a transcriptional repression domain in an insect Hox protein. Nature 415, 910-913.
16. Gebelein, B., and Urrutia, R. (2001). Sequence-specific transcriptional repression by KS1, a multiple-zinc-finger-Kruppel-associated box protein. Mol. Cell. Biol. 21, 928-939.
17. Gellon, G., and McGinnis, W. (1998). Shaping animal body plans in development and evolution by modulation of Hox expression patterns. Bioessays 20, 116-125.
18. Gibson, G., Schier, A., LeMotte, P., and Gehring, W.J. (1990). The specificities of Sex combs reduced and Antennapedia are defined by a distinct portion of each protein that includes the homeodomain. Cell 62, 1087-1103.
19. Graba, Y., Aragnol, D., and Pradel, J. (1997). Drosophila Hox complex downstream targets and the function of homeotic genes. Bioessays 19, 379-388.
20. Grenier, J.K., and Carroll, S.B. (2000). Functional evolution of the Ultrabithorax protein. Proc. Natl. Acad. Sci. USA 97, 704-709.
21. Guichet, A., Copeland, J.W., Erdelyi, M., Hlousek, D., Zavorszky, P., Ho, J., Brown, S., Percival-Smith, A., Krause, H.M., and Ephrussi, A. (1997). The nuclear receptor homologue Ftz-F1 and the homeodomain protein Ftz are mutually dependent cofactors. Nature 385, 548-552.
22. Henderson, K.D., and Andrew, D.J. (2000). Regulation and function of Scr, exd, and hth in the Drosophila salivary gland. Dev. Biol. 217, 362-374.
23. Jacobs, Y., Schnabel, C.A., and Cleary, M.L. (1999). Trimeric association of Hox and TALE homeodomain proteins mediates Hoxb2 hindbrain enhancer activity. Mol. Cell. Biol. 19, 5134-5142.
24. Jaffe, L., Ryoo, H.D., and Mann, R.S. (1997). A role for phosphorylation by casein kinase 2 in modulating Antennapedia function in Drosophila. Genes Dev. 11, 1327-1340.
25. Kornfeld, K., Saint, R.B., Beachy, P.A., Harte, P.J., Peattie, D.A., and Hogness, D.S. (1989). Structure and expression of a family of Ultrabithorax mRNAs generated by alternative splicing and polyadenylation in Drosophila. Genes Dev. 3, 243-258.
26. Kuziora, M.A., and McGinnis, W. (1989). A homeodomain substitution changes the regulatory specificity of the deformed protein in Drosophila embryos. Cell 59, 563-571.
27. Lefstin, J.A., and Yamamoto, K.R. (1998). Allosteric effects of DNA on transcriptional regulators. Nature 392, 885-888.
28. Li, X., and McGinnis, W.M. (1999). Activity regulation of Hox proteins, a mechanism for altering functional specificity in development and evolution. Proc. Natl. Acad. Sci. USA 96, 6802-6807.
29. Li, T., Stark, M., Johnson, A., and Wolberger, C. (1995). Crystal structure of the MATa1/MATα2 homeodomain heterodimer bound to DNA. Science 270, 262-269.
30. Li, X., Murre, C., and McGinnis, W. (1999). Activity regulation of a Hox protein and a role for the homeodomain in inhibiting transcriptional activation. EMBO J. 18, 198-211.
31. Lin, L., and McGinnis, W. (1992). Mapping functional specificity in the Dfd and Ubx homeo domains. Genes Dev. 6, 1071-1081.
32. Lopez, A.J., and Hogness, D.S. (1991). Immunochemical dissection of the Ultrabithorax homeoprotein family in Drosophila melanogaster. Proc. Natl. Acad. Sci. USA 88, 9924-9928.
33. Mann, R.S., and Affolter, M. (1998). Hox proteins meet more partners. Curr. Opin. Genet. Dev. 8, 423-429.
34. Mann, R.S., and Chan, S.-K. (1996). Extra specificity from extradenticle: the partnership between HOX and exd/pbx homeodomain proteins. Trends Genet. 12, 258-262.
35. Mann, R.S., and Hogness, D.S. (1990). Functional dissection of Ultrabithorax proteins in D. melanogaster. Cell 60, 597-610.
36. McGinnis, W., and Krumlauf, R. (1992). Homeobox genes and axial patterning. Cell 68, 283-302.
37. Nasiadka, A., Grill, A., and Krause, H.M. (2000). Mechanisms regulating target gene selection by the homeodomain-containing protein Fushi tarazu. Development 127, 2965-2976.
38. Palopoli, M.F., and Patel, N.H. (1998). Evolution of the interaction between Hox genes and a downstream target. Curr. Biol. 8, 587-590.
39. Panganiban, G., Irvine, S.M., Lowe, C., Roehl, H., Corley, L.S., Sherbon, B., Grenier, J.K., Fallon, J.F., Kimble, J., Walker, M., et al. (1997). The origin and evolution of animal appendages. Proc. Natl. Acad. Sci. USA 94, 5162-5166.
40. Passner, J.M., Ryoo, H.D., Shen, L., Mann, R.S., and Aggarwal, A.K. (1999). Structure of a DNA-bound Ultrabithorax-Extradenticle homeodomain complex. Nature 397, 714-718.
41. Peifer, M., and Wieschaus, E. (1990). Mutations in the Drosophila gene extradenticle affect the way specific homeo domain proteins regulate segmental identity. Genes Dev. 4, 1209-1223.
42. Piper, D.E., Batchelor, A.H., Chang, C.-P., Cleary, M.L., and Wolberger, C. (1999). Structure of a HoxB1-Pbx1 heterodimer bound to DNA: role of the hexapeptide and a fourth homeodomain helix in complex formation. Cell 96, 587-597.
43. Ronshaugen, M., McGinnis, N., and McGinnis, W. (2002). Hox protein mutation and macroevolution of the insect body plan. Nature 415, 914-917.
44. Ryoo, H.-D., and Mann, R.S. (1999). The control of trunk Hox specificity and activity by Extradenticle. Genes Dev. 13, 1704-1716.
45. Ryoo, H.-D., Marty, T., Casares, F., Affolter, M., and Mann, R.S. (1999). Regulation of Hox target genes by a DNA bound Homothorax/Hox/Extradenticle complex. Development 126, 5137-5148.
46. Scully, K.M., Jacobson, E.M., Jepsen, K., Lunyak, V., Viadiu, H., Carriere, C., Rose, D.W., Hooshmand, F., Aggarwal, A.K., and Rosenfeld, M.G. (2000). Allosteric effects of Pit-1 DNA sites on long-term repression in cell type specification. Science 290, 1127-1131.
47. Sun, B., Hursh, D.A., Jackson, D., and Beachy, P.A. (1995). Ultrabithorax protein is necessary but not sufficient for full activation of decapentaplegic expression in the visceral mesoderm. EMBO J. 14, 520-535.
48. Thanos, D., and Maniatis, T. (1996). In vitro assembly of enhancer complexes. Methods Enzymol. 274, 162-173.
49. Vachon, G., Cohen, B., Pfeifle, C., McGuffin, M.E., Botas, J., and Cohen, S. (1992). Homeotic genes of the Bithorax complex repress limb development in the abdomen of the Drosophila embryo through the target gene Distal-less. Cell 71, 437-450.
50. Weatherbee, S.D., and Carroll, S.B. (1999). Selector genes and limb identity in arthropods and vertebrates. Cell 30, 283-286.
51. White, R.A.H., and Wilcox, M. (1985). Distribution of Ultrabithorax proteins in Drosophila. EMBO J. 4, 2035-2043.
52. White, R.A., Aspland, S.E., Brookman, J.J., Clayton, L., and Sproat, G. (2000). The design and analysis of a homeotic response element. Mech. Dev. 91, 217-226.
53. Yu, Y., Li, W., Su, K., Yussa, M., Han, W., Perrimon, N., and Pick, L. (1997). The nuclear hormone receptor Ftz-F1 is a cofactor for the Drosophila homeodomain protein Ftz. Nature 385, 552-555.
54. Zeng, W., Andrew, D.J., Mathies, L.D., Horner, M.A., and Scott, M.P. (1993). Ectopic expression and function of the Antp and Scr homeotic genes: the N terminus of the homeodomain is critical to functional specificity. Development 118, 339-352.