메뉴 건너뛰기




Volumn 16, Issue 4, 1996, Pages 1734-1745

Pbx modulation of Hox homeodomain amino-terminal arms establishes different DNA-binding specificities across the Hox locus

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; HOMEODOMAIN PROTEIN; REGULATOR PROTEIN;

EID: 0029939199     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.16.4.1734     Document Type: Article
Times cited : (253)

References (87)
  • 2
    • 0024592814 scopus 로고
    • Hox and Hom: Homologous gene clusters in insects and vertebrates
    • Akam, M. 1989. Hox and Hom: homologous gene clusters in insects and vertebrates. Cell 57:347-349.
    • (1989) Cell , vol.57 , pp. 347-349
    • Akam, M.1
  • 3
    • 0027372533 scopus 로고
    • Cooperative binding of an Ultrabithorax homeo domain protein to nearby and distant DNA sites
    • Beachy, P. A., J. Varkey, K. E. Young, D. P. von Kessler, B. I. Sun, and S. C. Ekker. 1993. Cooperative binding of an Ultrabithorax homeo domain protein to nearby and distant DNA sites. Mol. Cell. Biol. 13:6941-6956.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 6941-6956
    • Beachy, P.A.1    Varkey, J.2    Young, K.E.3    Von Kessler, D.P.4    Sun, B.I.5    Ekker, S.C.6
  • 4
    • 0028821180 scopus 로고
    • Ultrabithorax protein is necessary but not sufficient for full activation of decapentaplegic expression in the visceral mesoderm
    • Benjamin, S., D. A. Hursh, D. Jackson, and P. A. Beachy. 1995. Ultrabithorax protein is necessary but not sufficient for full activation of decapentaplegic expression in the visceral mesoderm. EMBO J. 14:520-535.
    • (1995) EMBO J. , vol.14 , pp. 520-535
    • Benjamin, S.1    Hursh, D.A.2    Jackson, D.3    Beachy, P.A.4
  • 5
    • 0028816929 scopus 로고
    • The expression pattern of the murine Hoxa-10 gene and the sequence recognition of its homeodomain reveal specific properties of Abdominal B-like genes
    • Benson, G. V., T.-H. E. Nguyen, and R. L. Mass. 1995. The expression pattern of the murine Hoxa-10 gene and the sequence recognition of its homeodomain reveal specific properties of Abdominal B-like genes. Mol. Cell Biol. 15:1591-1601
    • (1995) Mol. Cell Biol. , vol.15 , pp. 1591-1601
    • Benson, G.V.1    Nguyen, T.-H.E.2    Mass, R.L.3
  • 6
    • 0027787519 scopus 로고
    • Determination of the NMR solution structure of an Antennapedia homeodomain-DNA complex
    • Billeter, M., Y. Q. Qian, G. Otting, M. Muller, W. Gehring, and K. Wüthrich. 1993. Determination of the NMR solution structure of an Antennapedia homeodomain-DNA complex J. Mol. Biol. 234:1084-1093.
    • (1993) J. Mol. Biol. , vol.234 , pp. 1084-1093
    • Billeter, M.1    Qian, Y.Q.2    Otting, G.3    Muller, M.4    Gehring, W.5    Wüthrich, K.6
  • 7
    • 0025572707 scopus 로고
    • Differences and similarities in DNA-binding preferences of MyoD and E2A protein complexes revealed by binding site selection
    • Blackwell, T. K., and H. Weintraub. 1990 Differences and similarities in DNA-binding preferences of MyoD and E2A protein complexes revealed by binding site selection Science 250:1104-1110.
    • (1990) Science , vol.250 , pp. 1104-1110
    • Blackwell, T.K.1    Weintraub, H.2
  • 8
    • 0000071294 scopus 로고
    • A comprehensive classification of homeobox genes
    • D. Duboule (ed.), Oxford University Press, Oxford
    • Bürglin, T. H. 1994 A comprehensive classification of homeobox genes, p. 27-41. In D. Duboule (ed.), Guidebook to the homeobox genes. Oxford University Press, Oxford.
    • (1994) Guidebook to the Homeobox Genes , pp. 27-41
    • Bürglin, T.H.1
  • 9
    • 0027412087 scopus 로고
    • Nucleotides flanking a conserved TAAT core dictate the DNA binding specificity of three murine homeodomain proteins
    • Catron, K. M., N. Her, and C. Abate. 1993 Nucleotides flanking a conserved TAAT core dictate the DNA binding specificity of three murine homeodomain proteins. Mol. Cell. Biol 13:2354-2365.
    • (1993) Mol. Cell. Biol , vol.13 , pp. 2354-2365
    • Catron, K.M.1    Her, N.2    Abate, C.3
  • 10
    • 0027191867 scopus 로고
    • The segment identity functions of ultrabithorax are contained within its homeodomain and carboxy-terminal sequences
    • Chan, K. S., and R. Mann. 1993. The segment identity functions of ultrabithorax are contained within its homeodomain and carboxy-terminal sequences. Genes Dev. 7:796-811.
    • (1993) Genes Dev. , vol.7 , pp. 796-811
    • Chan, K.S.1    Mann, R.2
  • 11
    • 0027966927 scopus 로고
    • The DNA binding specificity of Ultrabithorax is modulated by cooperative interactions with Extradenticle, another homeoprotein
    • Chan, S.-K., L. Jaffe, M. Capovilla, J. Botas, and R. S. Mann. 1994. The DNA binding specificity of Ultrabithorax is modulated by cooperative interactions with Extradenticle, another homeoprotein. Cell 78:603-615.
    • (1994) Cell , vol.78 , pp. 603-615
    • Chan, S.-K.1    Jaffe, L.2    Capovilla, M.3    Botas, J.4    Mann, R.S.5
  • 13
    • 0028947525 scopus 로고
    • Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins
    • Chang, C.-P., W.-F. Shen, S. Rozenfeld, H. J. Lawrence, C. Largman, and M. L. Cleary. 1995. Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins. Genes Dev. 9:663-674.
    • (1995) Genes Dev. , vol.9 , pp. 663-674
    • Chang, C.-P.1    Shen, W.-F.2    Rozenfeld, S.3    Lawrence, H.J.4    Largman, C.5    Cleary, M.L.6
  • 15
    • 0023729682 scopus 로고
    • The sequence specificity of homeodomain-DNA interaction
    • Desplan, C., J. Theis, and P. H. O'Farrell. 1988 The sequence specificity of homeodomain-DNA interaction. Cell 54:1081-1090.
    • (1988) Cell , vol.54 , pp. 1081-1090
    • Desplan, C.1    Theis, J.2    O'Farrell, P.H.3
  • 16
    • 0026557592 scopus 로고
    • Antp-like homeodomains have distinct DNA binding specificities that correlate with their different regulatory functions in embryos
    • Dessain, S., C. T. Gross, M. A. Kuziora, and W. McGinnis. 1992. Antp-like homeodomains have distinct DNA binding specificities that correlate with their different regulatory functions in embryos. EMBO J. 11:991-1002.
    • (1992) EMBO J. , vol.11 , pp. 991-1002
    • Dessain, S.1    Gross, C.T.2    Kuziora, M.A.3    McGinnis, W.4
  • 17
    • 0027936793 scopus 로고
    • The degree of variation in DNA sequence recognition among four Drosophila homeotic proteins
    • Ekker, S. C., D. G. Jackson, D. P. von Kessler, B. I. Sun, K. E. Young, and P. A. Beachy. 1994. The degree of variation in DNA sequence recognition among four Drosophila homeotic proteins. EMBO J. 13:3551-3560
    • (1994) EMBO J. , vol.13 , pp. 3551-3560
    • Ekker, S.C.1    Jackson, D.G.2    Von Kessler, D.P.3    Sun, B.I.4    Young, K.E.5    Beachy, P.A.6
  • 18
    • 0025764309 scopus 로고
    • Optimal DNA sequence recognition by the Ultrabithorax homeodomain of Drosophila
    • Ekker, S. C., K. E. Young, D. P. von Kessler, and P. A. Beachy. 1991. Optimal DNA sequence recognition by the Ultrabithorax homeodomain of Drosophila. EMBO J. 10:1179-1186.
    • (1991) EMBO J. , vol.10 , pp. 1179-1186
    • Ekker, S.C.1    Young, K.E.2    Von Kessler, D.P.3    Beachy, P.A.4
  • 21
    • 0025188768 scopus 로고
    • The specificities of Sexcombs Reduced and Antennapedia are defined by a distinct portion of each protein that includes the homeodomain
    • Gibson, G., A. Schier, P. LeMotte, and W. J. Gehring. 1990. The specificities of Sexcombs Reduced and Antennapedia are defined by a distinct portion of each protein that includes the homeodomain. Cell 62:1087-1103
    • (1990) Cell , vol.62 , pp. 1087-1103
    • Gibson, G.1    Schier, A.2    LeMotte, P.3    Gehring, W.J.4
  • 22
    • 0026744318 scopus 로고
    • Human and Drosophila homeodomain proteins that enhance the DNA-binding activity of serum response factor
    • Grueneberg, D. A., S. Natesan, C. Alexander, and M. Z. Gilman. 1992. Human and Drosophila homeodomain proteins that enhance the DNA-binding activity of serum response factor Science 257:1089-1095.
    • (1992) Science , vol.257 , pp. 1089-1095
    • Grueneberg, D.A.1    Natesan, S.2    Alexander, C.3    Gilman, M.Z.4
  • 23
    • 0024320441 scopus 로고
    • DNA specificity of the bicoid activator protein is determined by homeodomain recognition helix residue 9
    • Hanes, S. D., and R. Brent. 1989. DNA specificity of the bicoid activator protein is determined by homeodomain recognition helix residue 9. Cell 57:1275-1283.
    • (1989) Cell , vol.57 , pp. 1275-1283
    • Hanes, S.D.1    Brent, R.2
  • 24
    • 0025602459 scopus 로고
    • What determines the specificity of action of Drosophila homeodomain proteins?
    • Hayashi, S., and M. P. Scott. 1990. What determines the specificity of action of Drosophila homeodomain proteins? Cell 63:883-894.
    • (1990) Cell , vol.63 , pp. 883-894
    • Hayashi, S.1    Scott, M.P.2
  • 25
    • 0029124988 scopus 로고
    • The POU domain, versatility in transcriptional regulation by a flexible two-in-one DNA-binding domain
    • Herr, W., and M. A. Cleary. 1995. The POU domain, versatility in transcriptional regulation by a flexible two-in-one DNA-binding domain Genes Dev. 9:1679-1693.
    • (1995) Genes Dev. , vol.9 , pp. 1679-1693
    • Herr, W.1    Cleary, M.A.2
  • 26
    • 0024298689 scopus 로고
    • Divergent homeo box proteins recognize similar DNA sequences in Drosophila
    • Hoey, T., and M. Levine. 1988. Divergent homeo box proteins recognize similar DNA sequences in Drosophila. Nature (London) 332:858-861.
    • (1988) Nature (London) , vol.332 , pp. 858-861
    • Hoey, T.1    Levine, M.2
  • 27
    • 0028144968 scopus 로고
    • DNA-binding and transcriptional regulatory properties of hepatic leukemia factor (HLF) and the t(17;19) acute lymphoblastic leukemia chimera E2a-HLF
    • Hunger, S. P., R. Brown, and M. L. Cleary. 1994. DNA-binding and transcriptional regulatory properties of hepatic leukemia factor (HLF) and the t(17;19) acute lymphoblastic leukemia chimera E2a-HLF. Mol Cell. Biol. 14:5986-5996.
    • (1994) Mol Cell. Biol. , vol.14 , pp. 5986-5996
    • Hunger, S.P.1    Brown, R.2    Cleary, M.L.3
  • 28
    • 0025339078 scopus 로고
    • The POU-specific domain of Pit-1 is essential for sequence-specific, high affinity DNA binding and DNA-dependent Pit-1-Pit-1 interactions
    • Ingraham, H. A., S. E. Flynn, J. W. Voss, V. R. Albert, M. S. Kapiloff, L. Wilson, and M. G. Rosenfeld. 1990. The POU-specific domain of Pit-1 is essential for sequence-specific, high affinity DNA binding and DNA-dependent Pit-1-Pit-1 interactions. Cell 61:1021-1033.
    • (1990) Cell , vol.61 , pp. 1021-1033
    • Ingraham, H.A.1    Flynn, S.E.2    Voss, J.W.3    Albert, V.R.4    Kapiloff, M.S.5    Wilson, L.6    Rosenfeld, M.G.7
  • 29
    • 0025785350 scopus 로고
    • Murine genes related to the Drosophila AbdB homeotic gene are sequentially expressed during development of the posterior part of the body
    • Ispisúa-Belmonte, J.-C., H. Falkenstein, P. Dollé, A. Renucci, and D. Deboule. 1991. Murine genes related to the Drosophila AbdB homeotic gene are sequentially expressed during development of the posterior part of the body. EMBO J. 10:2279-2289.
    • (1991) EMBO J. , vol.10 , pp. 2279-2289
    • Ispisúa-Belmonte, J.-C.1    Falkenstein, H.2    Dollé, P.3    Renucci, A.4    Deboule, D.5
  • 30
    • 0027422972 scopus 로고
    • E2A expression, nuclear localization, and in vivo formation of DNA- and non-DNA-binding species during B-cell development
    • Jacobs, Y., C. Vierra, and C. Nelson. 1993. E2A expression, nuclear localization, and in vivo formation of DNA- and non-DNA-binding species during B-cell development. Mol. Cell. Biol. 13:7321-7333.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 7321-7333
    • Jacobs, Y.1    Vierra, C.2    Nelson, C.3
  • 31
    • 0001294043 scopus 로고
    • A combinatorial regulatory circuit in budding yeast
    • S. L. McKnight and K. R Yamamoto (ed.), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
    • Johnson, A. 1992 A combinatorial regulatory circuit in budding yeast, p. 975-1006. In S. L. McKnight and K. R Yamamoto (ed.), Transcriptional regulation. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
    • (1992) Transcriptional Regulation , pp. 975-1006
    • Johnson, A.1
  • 32
    • 0028809109 scopus 로고
    • Extradenticle protein is a selective cofactor for the Drosophila homeotics: Role of the homeodomain and YPWM motif in the interaction
    • Johnson, F. B., E. Parker, and M. A. Krasnow. 1995. extradenticle protein is a selective cofactor for the Drosophila homeotics: role of the homeodomain and YPWM motif in the interaction. Proc. Natl Acad. Sci. USA 92:739-743.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 739-743
    • Johnson, F.B.1    Parker, E.2    Krasnow, M.A.3
  • 33
    • 0025137176 scopus 로고
    • A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B ALL
    • Kamps, M. P., C. M. Murre, X.-H. Sun, and D. Baltimore. 1990. A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B ALL. Cell 60:547-555.
    • (1990) Cell , vol.60 , pp. 547-555
    • Kamps, M.P.1    Murre, C.M.2    Sun, X.-H.3    Baltimore, D.4
  • 34
    • 0025321338 scopus 로고
    • Analysis of the human liver/bone/ kidney alkaline phosphatase promoter in vivo and in vitro
    • Kiledjian, M., and T. Kadesch. 1990. Analysis of the human liver/bone/ kidney alkaline phosphatase promoter in vivo and in vitro. Nucleic Acids Res 18:957-961.
    • (1990) Nucleic Acids Res , vol.18 , pp. 957-961
    • Kiledjian, M.1    Kadesch, T.2
  • 35
    • 0025188837 scopus 로고
    • Crystal structure of an engrailed homeodomain-DNA complex at 2.8 Å resolution: A framework for understanding homeodomain-DNA interactions
    • Kissinger, C. R., B. Liu, E. Martin-Blanco, T. B. Kornberg, and C. O. Pabo. 1990. Crystal structure of an engrailed homeodomain-DNA complex at 2.8 Å resolution: a framework for understanding homeodomain-DNA interactions. Cell 63:579-590.
    • (1990) Cell , vol.63 , pp. 579-590
    • Kissinger, C.R.1    Liu, B.2    Martin-Blanco, E.3    Kornberg, T.B.4    Pabo, C.O.5
  • 36
    • 0029118224 scopus 로고
    • The pentapeptide motif of Hox proteins is required for cooperative DNA binding with Pbx1, physically contacts Pbx1, and enhances DNA binding by Pbx1
    • Knoefler, P. S., and M. P. Kamps. 1995. The pentapeptide motif of Hox proteins is required for cooperative DNA binding with Pbx1, physically contacts Pbx1, and enhances DNA binding by Pbx1. Mol. Cell Biol. 15:5811-5819.
    • (1995) Mol. Cell Biol. , vol.15 , pp. 5811-5819
    • Knoefler, P.S.1    Kamps, M.P.2
  • 37
    • 0027953771 scopus 로고
    • Hox genes in vertebrate development
    • Krumlauf, R. 1994. Hox genes in vertebrate development. Cell 78:191-201.
    • (1994) Cell , vol.78 , pp. 191-201
    • Krumlauf, R.1
  • 38
    • 0024342893 scopus 로고
    • A homeodomain substitution changes the regulatory specificity of the Deformed protein in Drosophila embryos
    • Kuziora, M. A., and W. McGinnis. 1989. A homeodomain substitution changes the regulatory specificity of the Deformed protein in Drosophila embryos. Cell 59:563-571.
    • (1989) Cell , vol.59 , pp. 563-571
    • Kuziora, M.A.1    McGinnis, W.2
  • 39
    • 0026321622 scopus 로고
    • DNA binding specificity of homeodomains
    • Laughon, A. 1991. DNA binding specificity of homeodomains. Biochemistry 30:11357-11367.
    • (1991) Biochemistry , vol.30 , pp. 11357-11367
    • Laughon, A.1
  • 40
    • 0026485281 scopus 로고
    • Homeobox genes in normal hematopoiesis and leukemia
    • Lawrence, H. J., and C. Largman. 1992 Homeobox genes in normal hematopoiesis and leukemia. Blood 80:2445-2453.
    • (1992) Blood , vol.80 , pp. 2445-2453
    • Lawrence, H.J.1    Largman, C.2
  • 41
    • 0028303736 scopus 로고
    • Fusion with E2A alters the transcriptional properties of the homeodomain protein PBX1 in t(1;19) leukemias
    • LeBrun, D. L., and M. L. Cleary. 1994. Fusion with E2A alters the transcriptional properties of the homeodomain protein PBX1 in t(1;19) leukemias. Oncogene 9:1641-1647.
    • (1994) Oncogene , vol.9 , pp. 1641-1647
    • LeBrun, D.L.1    Cleary, M.L.2
  • 42
    • 0021095856 scopus 로고
    • Protein folding by restrained energy minimization and molecular dynamics
    • Levitt, M. 1983. Protein folding by restrained energy minimization and molecular dynamics. J. Mol. Biol. 170:723-764.
    • (1983) J. Mol. Biol. , vol.170 , pp. 723-764
    • Levitt, M.1
  • 43
    • 0026754015 scopus 로고
    • Accurate modeling of protein conformation by automatic segment matching
    • Levitt, M. 1992. Accurate modeling of protein conformation by automatic segment matching. J. Mol. Biol. 226:507-533.
    • (1992) J. Mol. Biol. , vol.226 , pp. 507-533
    • Levitt, M.1
  • 44
    • 0026718999 scopus 로고
    • Mapping functional specificity in the Dfd and Ubx homeo domains
    • Lin, L., and W. McGinnis. 1992. Mapping functional specificity in the Dfd and Ubx homeo domains. Genes Dev 6:1071-1081.
    • (1992) Genes Dev , vol.6 , pp. 1071-1081
    • Lin, L.1    McGinnis, W.2
  • 45
    • 0029054140 scopus 로고
    • Both Pbx1 and E2A-Pbx1 bind the DNA motif ATCAATCAA cooperatively with the products of multiple murine Hox genes, some of which are themselves oncogenes
    • Lu, Q., P. S. Knoepfler, J. Scheele, D. D. Wright, and M. P. Kamps. 1995. Both Pbx1 and E2A-Pbx1 bind the DNA motif ATCAATCAA cooperatively with the products of multiple murine Hox genes, some of which are themselves oncogenes. Mol. Cell. Biol. 15:3786-3795.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 3786-3795
    • Lu, Q.1    Knoepfler, P.S.2    Scheele, J.3    Wright, D.D.4    Kamps, M.P.5
  • 46
    • 0028231938 scopus 로고
    • Fusion with E2A converts the Pbx1 homeodomain protein into a constitutive transcriptional activator in human leukemias carrying the t(1;19) translocation
    • Lu, Q., D. D. Wright, and M. P. Kamps. 1994. Fusion with E2A converts the Pbx1 homeodomain protein into a constitutive transcriptional activator in human leukemias carrying the t(1;19) translocation. Mol. Cell. Biol. 14: 3938-3948.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 3938-3948
    • Lu, Q.1    Wright, D.D.2    Kamps, M.P.3
  • 47
    • 0027443311 scopus 로고
    • Functional analysis of the mouse homeobox gene HoxB9 in Drosophila development
    • Malicki, J., L. D. Bogorad, M. M. Martin, F. H. Ruddle, and W. McGinnis. 1993. Functional analysis of the mouse homeobox gene HoxB9 in Drosophila development. Mech. Dev. 42:139-150.
    • (1993) Mech. Dev. , vol.42 , pp. 139-150
    • Malicki, J.1    Bogorad, L.D.2    Martin, M.M.3    Ruddle, F.H.4    McGinnis, W.5
  • 48
    • 0028090636 scopus 로고
    • Regulation of a decapentaplegic midgut enhancer by homeotic proteins
    • Manak, J., L. Mathies, and M. Scott. 1995. Regulation of a decapentaplegic midgut enhancer by homeotic proteins. Development 120:3605-3619.
    • (1995) Development , vol.120 , pp. 3605-3619
    • Manak, J.1    Mathies, L.2    Scott, M.3
  • 49
    • 0025017612 scopus 로고
    • Functional dissection of Ultrabithorax proteins in D. melanogaster
    • Mann, R. S., and D. S. Hogness. 1990. Functional dissection of Ultrabithorax proteins in D. melanogaster Cell 60:597-610.
    • (1990) Cell , vol.60 , pp. 597-610
    • Mann, R.S.1    Hogness, D.S.2
  • 50
    • 0026504525 scopus 로고
    • Homeobox genes and axial patterning
    • McGinnis, W., and R. Krumlauf. 1992. Homeobox genes and axial patterning. Cell 68:283-302.
    • (1992) Cell , vol.68 , pp. 283-302
    • McGinnis, W.1    Krumlauf, R.2
  • 51
    • 0026337299 scopus 로고
    • Characterization of a cofactor that regulates dimerization of a mammalian homeodomain protein
    • Mendel, D. B., P. A. Khavari, P. B. Conley, M. K. Graves, L. P. Hansen, A. Admon, and G. R. Crabtree. 1991. Characterization of a cofactor that regulates dimerization of a mammalian homeodomain protein. Science 254: 1762-1767.
    • (1991) Science , vol.254 , pp. 1762-1767
    • Mendel, D.B.1    Khavari, P.A.2    Conley, P.B.3    Graves, M.K.4    Hansen, L.P.5    Admon, A.6    Crabtree, G.R.7
  • 52
    • 0026066608 scopus 로고
    • PBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1
    • Monica, K., N. Galili, J. Nourse, D. Saltman, and M. L. Cleary. 1991. PBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1. Mol. Cell. Biol. 11:6149-6157.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 6149-6157
    • Monica, K.1    Galili, N.2    Nourse, J.3    Saltman, D.4    Cleary, M.L.5
  • 53
    • 0028089760 scopus 로고
    • Transformation properties of the E2a-Pbx1 chimeric oncoprotein: Fusion with E2a is essential but the Pbx1 homeodomain is dispensable
    • Monica, K., D. L. LeBrun, D. A. Dedera, R. Brown, and M. L. Cleary. 1994. Transformation properties of the E2a-Pbx1 chimeric oncoprotein: fusion with E2a is essential but the Pbx1 homeodomain is dispensable. Mol. Cell. Biol. 14:8304-8313.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 8304-8313
    • Monica, K.1    LeBrun, D.L.2    Dedera, D.A.3    Brown, R.4    Cleary, M.L.5
  • 54
    • 0342759569 scopus 로고
    • Isolation and sequence-specific DNA binding of the Antennapedia homeodomain
    • Müller, M., M. Affolter, W. Leupin, G. Otting, K. Wüthrich, and W. J. Gehring. 1988. Isolation and sequence-specific DNA binding of the Antennapedia homeodomain. EMBO J. 7:4299-4304.
    • (1988) EMBO J. , vol.7 , pp. 4299-4304
    • Müller, M.1    Affolter, M.2    Leupin, W.3    Otting, G.4    Wüthrich, K.5    Gehring, W.J.6
  • 55
    • 0029079663 scopus 로고
    • The hexapeptide LFPWMR in Hoxb-8 is required for cooperative DNA binding with Pbx1 and Pbx2 proteins
    • Neuteboom, S. T. C., L. T. C. Peltenhurg, M. A. van Dyk, and C. Murre. 1995. The hexapeptide LFPWMR in Hoxb-8 is required for cooperative DNA binding with Pbx1 and Pbx2 proteins. Proc. Natl. Acad. Sci USA 92:9166-9170.
    • (1995) Proc. Natl. Acad. Sci USA , vol.92 , pp. 9166-9170
    • Neuteboom, S.T.C.1    Peltenhurg, L.T.C.2    Van Dyk, M.A.3    Murre, C.4
  • 56
    • 0025064238 scopus 로고
    • Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor
    • Nourse, J., J. D. Mellentin, N. Galili, J. Wilkinson, E. Stanbridge, S. D. Smith, and M. L. Cleary. 1990. Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor. Cell 60:535-546.
    • (1990) Cell , vol.60 , pp. 535-546
    • Nourse, J.1    Mellentin, J.D.2    Galili, N.3    Wilkinson, J.4    Stanbridge, E.5    Smith, S.D.6    Cleary, M.L.7
  • 58
    • 0024997404 scopus 로고
    • Protein-DNA contacts in the structure of a homeodomain-DNA complex determined by nuclear magnetic resonance spectroscopy in solution
    • Otting, G., Y. Q. Qian, M. Billeter, M. Müller, M. Affolter, W. J. Gehring, and K. Wüthrich. 1990. Protein-DNA contacts in the structure of a homeodomain-DNA complex determined by nuclear magnetic resonance spectroscopy in solution EMBO J. 9:3085-3092.
    • (1990) EMBO J. , vol.9 , pp. 3085-3092
    • Otting, G.1    Qian, Y.Q.2    Billeter, M.3    Müller, M.4    Affolter, M.5    Gehring, W.J.6    Wüthrich, K.7
  • 59
    • 0025365228 scopus 로고
    • Mutations in the Drosophila gene extradenticle affect the way specific homeo domain proteins regulate segmental identity
    • Peifer, M., and E. Wieschaus. 1990. Mutations in the Drosophila gene extradenticle affect the way specific homeo domain proteins regulate segmental identity. Genes Dev. 4:1209-1223.
    • (1990) Genes Dev. , vol.4 , pp. 1209-1223
    • Peifer, M.1    Wieschaus, E.2
  • 60
    • 0028360777 scopus 로고
    • Hox proteins have different affinities for a consensus DNA site that correlate with the positions of their genes on the hox cluster
    • Pellerin, I., C. Schnabel, K. M. Catron, and C. Abate. 1994. Hox proteins have different affinities for a consensus DNA site that correlate with the positions of their genes on the hox cluster. Mol. Cell. Biol. 14:4532-1545.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 4532-11545
    • Pellerin, I.1    Schnabel, C.2    Catron, K.M.3    Abate, C.4
  • 62
    • 0029008293 scopus 로고
    • Cooperative interactions between HOX and PBX proteins mediated by a conserved peptide motif
    • Phelan, M. L., I. Rambaldi, and M. S. Featherstone. 1995. Cooperative interactions between HOX and PBX proteins mediated by a conserved peptide motif. Mol. Cell. Biol. 15:3989-3997.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 3989-3997
    • Phelan, M.L.1    Rambaldi, I.2    Featherstone, M.S.3
  • 63
    • 0028146174 scopus 로고
    • Functional differences between HOX proteins conferred by two residues in the homeodomain N-terminal arm
    • Phelan, M. L., R. Sadoul, and M. S. Featherstone. 1994. Functional differences between HOX proteins conferred by two residues in the homeodomain N-terminal arm. Mol. Cell. Biol. 14:5066-5075.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 5066-5075
    • Phelan, M.L.1    Sadoul, R.2    Featherstone, M.S.3
  • 64
    • 0028142407 scopus 로고
    • Heterodimerization of the yeast homeodomain transcriptional regulators α2 and a1 induces an interfacial helix in α2
    • Phillips, C. L., M. R. Stark, A. D. Johnson, and F. W. Dahlquist. 1994. Heterodimerization of the yeast homeodomain transcriptional regulators α2 and a1 induces an interfacial helix in α2. Biochemistry 33:9294-9302.
    • (1994) Biochemistry , vol.33 , pp. 9294-9302
    • Phillips, C.L.1    Stark, M.R.2    Johnson, A.D.3    Dahlquist, F.W.4
  • 65
    • 0029055810 scopus 로고
    • Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx
    • Popperl, H., M. Bienz, M. Studer, S.-K. Chan, S. Aparicio, S. Brenner, R. S. Mann, and R. Krumlauf. 1995 Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx. Cell 81:1031-1042.
    • (1995) Cell , vol.81 , pp. 1031-1042
    • Popperl, H.1    Bienz, M.2    Studer, M.3    Chan, S.-K.4    Aparicio, S.5    Brenner, S.6    Mann, R.S.7    Krumlauf, R.8
  • 66
    • 0027519720 scopus 로고
    • Extradenticle, a regulator of homeotic gene activity, is a homolog of the homeobox-containing human proto-oncogene PBX1
    • Rauskolb, C., M. Peifer, and E. Wieschaus. 1993. extradenticle, a regulator of homeotic gene activity, is a homolog of the homeobox-containing human proto-oncogene PBX1. Cell 74:1101-1112.
    • (1993) Cell , vol.74 , pp. 1101-1112
    • Rauskolb, C.1    Peifer, M.2    Wieschaus, E.3
  • 67
    • 0028858251 scopus 로고
    • Extradenticle determines segmental identities throughout Drosophila development
    • Rauskolb, C., K. M. Smith, M. Peifer, and E. Wieschaus. 1995. extradenticle determines segmental identities throughout Drosophila development. Development 121:3663-3673.
    • (1995) Development , vol.121 , pp. 3663-3673
    • Rauskolb, C.1    Smith, K.M.2    Peifer, M.3    Wieschaus, E.4
  • 68
    • 0027934301 scopus 로고
    • Coordinate regulation of downstream genes by extradenticle and the homeotic selector proteins
    • Rauskolb, C., and E. Wieschaus. 1994. Coordinate regulation of downstream genes by extradenticle and the homeotic selector proteins. EMBO J. 13:3561-3569.
    • (1994) EMBO J. , vol.13 , pp. 3561-3569
    • Rauskolb, C.1    Wieschaus, E.2
  • 69
    • 0025975559 scopus 로고
    • High-affinity binding sites for the Deformed protein are required for the function of an autoregulatory enhancer of the Deformed gene
    • Regulski, M., S. Dessain, N. McGinnis, and W. McGinnis. 1991. High-affinity binding sites for the Deformed protein are required for the function of an autoregulatory enhancer of the Deformed gene. Genes Dev. 5:278-286.
    • (1991) Genes Dev. , vol.5 , pp. 278-286
    • Regulski, M.1    Dessain, S.2    McGinnis, N.3    McGinnis, W.4
  • 70
    • 0025775278 scopus 로고
    • vHNF1 is a homeoprotein that activates transcription and forms heterodimers with HNF1
    • Rey-Campos, J., T. Chouard, M. Yaniv, and S. Cereghini. 1991. vHNF1 is a homeoprotein that activates transcription and forms heterodimers with HNF1. EMBO J. 10:1445-1457.
    • (1991) EMBO J. , vol.10 , pp. 1445-1457
    • Rey-Campos, J.1    Chouard, T.2    Yaniv, M.3    Cereghini, S.4
  • 71
    • 0028300741 scopus 로고
    • Combining evolutionary information and neural networks to predict protein secondary structure
    • Rost, B., and C. Sander. 1994. Combining evolutionary information and neural networks to predict protein secondary structure. Proteins 19:55-72.
    • (1994) Proteins , vol.19 , pp. 55-72
    • Rost, B.1    Sander, C.2
  • 72
    • 0025342556 scopus 로고
    • Specific DNA binding of the two chicken Deformed family homeodomain proteins, Chox-1.4 and Chox-a
    • Sasaki, H., E. Yokoyama, and A. Kuroiwa. 1990. Specific DNA binding of the two chicken Deformed family homeodomain proteins, Chox-1.4 and Chox-a. Nucleic Acids Res. 18:1739-1747.
    • (1990) Nucleic Acids Res. , vol.18 , pp. 1739-1747
    • Sasaki, H.1    Yokoyama, E.2    Kuroiwa, A.3
  • 73
    • 0029091845 scopus 로고
    • Overexpression of HOXB4 in hematopoietic cells causes the selective expansion of more primitive populations in vitro and in vivo
    • Sauvageau, G., U. Thorsteinsdottir, C. J. Eaves, H. J. Lawrence, C. Largman, P. M. Lansdorp, and R. K. Humphries. 1995. Overexpression of HOXB4 in hematopoietic cells causes the selective expansion of more primitive populations in vitro and in vivo. Genes Dev. 9:1753-1765.
    • (1995) Genes Dev. , vol.9 , pp. 1753-1765
    • Sauvageau, G.1    Thorsteinsdottir, U.2    Eaves, C.J.3    Lawrence, H.J.4    Largman, C.5    Lansdorp, P.M.6    Humphries, R.K.7
  • 75
    • 0024465662 scopus 로고
    • The Oct-1 homeodomain directs formation of a multiprotein-DNA complex with the HSV transactivator VP16
    • Stern, S., M. Tanaka, and W. Herr. 1989. The Oct-1 homeodomain directs formation of a multiprotein-DNA complex with the HSV transactivator VP16. Nature (London) 341:624-630.
    • (1989) Nature (London) , vol.341 , pp. 624-630
    • Stern, S.1    Tanaka, M.2    Herr, W.3
  • 76
    • 0028821180 scopus 로고
    • Ultrabithorax protein is necessary but not sufficient for full activation of decapentaplegic expression in the viceral mesoderm
    • Sun, B., D. A. Hursh, D. Jackson, and P. A. Beachy. 1995. Ultrabithorax protein is necessary but not sufficient for full activation of decapentaplegic expression in the viceral mesoderm. EMBO J. 14:520-535.
    • (1995) EMBO J. , vol.14 , pp. 520-535
    • Sun, B.1    Hursh, D.A.2    Jackson, D.3    Beachy, P.A.4
  • 77
    • 0024397687 scopus 로고
    • A single amino acid can determine the DNA binding specificity of homeodomain proteins
    • Treisman, J., P. Gonczy, M. Vashishtha, E. Harris, and C. Desplan. 1989 A single amino acid can determine the DNA binding specificity of homeodomain proteins. Cell 59:553-562.
    • (1989) Cell , vol.59 , pp. 553-562
    • Treisman, J.1    Gonczy, P.2    Vashishtha, M.3    Harris, E.4    Desplan, C.5
  • 78
    • 0028169993 scopus 로고
    • Extradenticle raises the DNA binding specificity of homeotic selector gene products
    • van Dyk, M. A., and C. Murre. 1994. extradenticle raises the DNA binding specificity of homeotic selector gene products. Cell 78:617-624.
    • (1994) Cell , vol.78 , pp. 617-624
    • Van Dyk, M.A.1    Murre, C.2
  • 79
    • 0027176915 scopus 로고
    • Pbx1 is converted into a transcriptional activator upon acquiring the N-terminal region of E2A in pre-B-cell acute lymphoblastoid leukemia
    • van Dyk, M. A., P. M. Voorhoeve, and C. Murre. 1993. Pbx1 is converted into a transcriptional activator upon acquiring the N-terminal region of E2A in pre-B-cell acute lymphoblastoid leukemia. Proc. Natl. Acad. Sci. USA 90: 6061-6065.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 6061-6065
    • Van Dyk, M.A.1    Voorhoeve, P.M.2    Murre, C.3
  • 80
    • 0026515866 scopus 로고
    • The Oct-1 POU domain mediates interactions between Oct-1 and other POU proteins
    • Verrijzer, C. P., J. A. W. M. van Oosterhout, and P. C. van der Vliet 1992. The Oct-1 POU domain mediates interactions between Oct-1 and other POU proteins. Mol. Cell. Biol. 12:542-551.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 542-551
    • Verrijzer, C.P.1    Van Oosterhout, J.A.W.M.2    Van Der Vliet, P.C.3
  • 81
    • 0025878739 scopus 로고
    • POU-domain proteins Pit-1 and Oct-1 interact to form a heterodimeric complex and can cooperate to induce expression of the prolactin promoter
    • Voss, J. W., L. Wilson, and M. G. Rosenfeld. 1991. POU-domain proteins Pit-1 and Oct-1 interact to form a heterodimeric complex and can cooperate to induce expression of the prolactin promoter. Genes Dev. 5:1309-1320.
    • (1991) Genes Dev. , vol.5 , pp. 1309-1320
    • Voss, J.W.1    Wilson, L.2    Rosenfeld, M.G.3
  • 83
    • 84988053694 scopus 로고
    • An all atom force field for simulation of proteins and nucleic acids
    • Weiner, S. J., P. A. Kullman, D. T. Nguyen, and D. A. Case. 1986. An all atom force field for simulation of proteins and nucleic acids. J. Comput. Chem. 7:230-252
    • (1986) J. Comput. Chem. , vol.7 , pp. 230-252
    • Weiner, S.J.1    Kullman, P.A.2    Nguyen, D.T.3    Case, D.A.4
  • 84
    • 0026002757 scopus 로고
    • Crystal structure of the MATα2 homeodomain-operator complex suggests a general model for homeodomain-DNA interactions
    • Wolberger, C., A. K. Vershon, B. Liu, A. D. Johnson, and C. O. Pabo. 1991. Crystal structure of the MATα2 homeodomain-operator complex suggests a general model for homeodomain-DNA interactions. Cell 67:517-528.
    • (1991) Cell , vol.67 , pp. 517-528
    • Wolberger, C.1    Vershon, A.K.2    Liu, B.3    Johnson, A.D.4    Pabo, C.O.5
  • 85
    • 0027892020 scopus 로고
    • Cooperative interactions between the Caenorhabditis elegans homeoproteins UNC-86 and MEC-3
    • Xue, D., Y. Tu, and M. Chalfie. 1993. Cooperative interactions between the Caenorhabditis elegans homeoproteins UNC-86 and MEC-3. Science 261: 1324-1328.
    • (1993) Science , vol.261 , pp. 1324-1328
    • Xue, D.1    Tu, Y.2    Chalfie, M.3
  • 86
    • 0028350269 scopus 로고
    • Specificity of HOX protein function depends on DNA-protein and protein-protein interactions, both mediated by the homeo domain
    • Zappavigna, V., D. Sartori, and F. Mavilio. 1994. Specificity of HOX protein function depends on DNA-protein and protein-protein interactions, both mediated by the homeo domain. Genes Dev. 8:732-744.
    • (1994) Genes Dev. , vol.8 , pp. 732-744
    • Zappavigna, V.1    Sartori, D.2    Mavilio, F.3
  • 87
    • 0027288479 scopus 로고
    • Ectopic expression and function of the Antp and Sci homeotic genes the N terminus of the homeodomain is critical to functional specificity
    • Zeng, W., D. J. Andrew, L. D. Mathies, M. A. Horner, and M. P. Scott. 1993. Ectopic expression and function of the Antp and Sci homeotic genes the N terminus of the homeodomain is critical to functional specificity Development 118:339-352.
    • (1993) Development , vol.118 , pp. 339-352
    • Zeng, W.1    Andrew, D.J.2    Mathies, L.D.3    Horner, M.A.4    Scott, M.P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.