Drosophila Hox complex downstream targets and the function of homeotic genes

BioEssays

Volumn 19, Issue 5, 1997, Pages 379-388

  Graba, Yacine ^a   Aragnol, Denise ^a   Pradel, Jacques ^a  

^a CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0031149988     PISSN: 02659247     EISSN: None     Source Type: Journal    
DOI: 10.1002/bies.950190505     Document Type: Review

References (72)

1. Lewis, E. B. (1978). A gene complex controlling segmentation in Drosophila. Nature 276, 565-570.
2. Kaufman, T. C., Lewis, R., and Wakimoto, B. (1980). Cytogenetic analysis of chromosome 3 in Drosophila melanogaster. the homeotic gene complex in polytene chromosome interval 84A-B. Genetics 94, 115-133.
3. McGinnis, W. and Krumlauf, R. (1992). Homeobox genes and axial patterning. Cell 68, 283-302.
4. Morata, G. (1993). Homeotic genes in Drosophila. Curr. Opin. Genet. Dev. 3, 606-614.
5. Krumlauf, R. (1994). Hox genes in vertebrate development. Cell 78, 191-200.
6. Garcia-Bellido, A. (1975). Genetic control of the wing disc development in Drosophila. In Cell Patterning, Ciba Foundation Symposium 29, 161-178.
7. Desplan, C., Theis, J. and O'Farrell, P. H. (1988). The sequence specificity of homeodomain-DNA interaction. Cell 54, 1081-1090.
8. Ekker, S. C. et al. (1994). The degree of variation in DNA sequence recognition among four Drosophila homeotic proteins. EMBO J. 13, 3551-3560.
9. Krasnow, M., Saffman, E. E., Kornfeld, K. and Hogness, D. S. (1989). Transcriptional activation and repression by Ultrabithorax proteins in cultured Drosophila cells. Cell 57, 1031-1043.
10. Panzer, S., Weigel, D. and Beckendorf, S. K. (1992). Organogenesis in Drosophila: embryonic salivary gland determination is controlled by homeotic and dorso-ventral patterning genes. Development 114, 49-57.
11. Vachon, G., Cohen, B., Pfeifle, C., McGuffin, M. E., Botas, J. and Cohen, S. M. (1992). Homeotic genes of the Bithorax complex repress limb development in the abdomen of the Drosophila embryo through the target gene Distal-less. Cell 71, 437-450.
12. O'Hara, E., Cohen, B., Cohen, S. M. and McGinnis, W. (1993). Distal-less is a downstream gene of Deformed required for ventral maxillary identity. Development 117, 847-856.
13. Jones, B. and McGinnis, W. (1993). The regulation of empty spiracles by Abdominal-B mediates an abdominal segment identity function. Genes Dev. 7, 229-240.
14. Immergluck, K., Lawrence, P. A. and Bienz, M. (1990). Induction across germ layers in Drosophila mediated by a genetic cascade. Cell 62, 261-268.
15. Reuter, R. and Scott, M. P. (1990). Expression and function of the homeotic genes Antennapedia and Sex combs reduced in the embryonic midgut of Drosophila. Development 109, 289-303.
16. Graba, Y. et al. (1992). Homeotic control in Drosophila: the scabrous gene is an in vivo target of Ultrabithorax proteins. EMBO J. 9, 3375-3384.
17. McCormick, A., Coré, N., Kerridge, S. and Scott, M. P. (1995). Homeotic response elements are tightly linked to tissue specific elements in a transcriptional enhancer of the teashirt gene. Development 121, 2799-2812.
18. Hinz, U., Wolk, A. and Renkawitz-Pohl, R. (1992). Ultrabithorax is a regulator of ß3-tubulin expression in the Drosophila visceral mesoderm. Development 116, 543-554.
19. Cimbora, D., M. and Sakonju, S. (1995). Drosophila midgut morphogenesis requires the function of the segmentation gene odd-paired. Dev. Biol. 169, 580-95.
20. Graba, Y., Laurenti, P., Perrin, L., Aragnol, D. and Pradel, J. (1994). The suppressor of PEV modulo gene acts downstream selector genes and is required for morphogenesis. Dev. Biol. 166, 704-715.
21. Capovilla, M., Brandt, M. and Botas, J. (1994). Direct regulation of decapentaplegic by Ultrabithorax and its role in Drosophila midgut morphogenesis. Cell 76, 461-475.
22. Sun, B., Hursh, D., Jakson, D. and Beachy, P. A. (1995). Ultrabithorax protein is necessary but not sufficient for full activation of decapentaplegic expression in the visceral mesoderm. EMBO. J. 14, 520-535.
23. Wagner-Bernholz, J. T., Wilson, C., Gibson, G., Schuh, R. and Gehring, W. (1991). Identification of target genes of the homeotic gene Antennapedia by enhancer detection. Genes Dev. 5, 2467-2480.
24. Chiang C., Young, K. E. and Beachy, P. A. (1995). Control of Drosophila tracheal branching by the novel homeodomain gene unplugged, a regulatory target for genes of the bithorax complex. Development 121, 3901-3912.
25. Feinstein, P. G., Kornfeld, K., Hogness, D. S. and Mann, R. S. (1995). Identification of homeotic target genes in Drosophila melanogaster including nervy, a proto-oncogene homologue. Genetics 140, 573-586.
26. Mastick, G. S., McKay, R., Oligino, T., Donovan, K. and Lopez A. J. (1995). Identification of target genes regulated by homeotic proteins in Drosophila melanogaster through genetic selection of Ultrabithorax protein binding sites in yeast. Genetics 139, 349-363.
27. Gould, A. P., Brookman, J. J., Strutt, D. I. and White, R. A. H. (1990). Targets of homeotic gene control in Drosophila. Nature 348, 308-312.
28. Tomotsume, D., Shogi, H., Wakamutsu, Y., Kondoh, H. and Takahashi, N. (1993). A mouse homologue of the Drosophila tumor suppressor gene I(2)gl controlled by HOX-C8 in vivo. Nature 365, 69-72.
29. Gould, A. P. and White, R. A. H. (1992). Connectin a target of homeotic gene control in Drosophila. Development 116, 1163-1174.
30. Strutt, D. I. and White, R. A. H. (1994) Characterisation of T48, a target of homeotic gene regulation in Drosophila embryogenesis. Mech. Dev. 46, 27-39.
31. Brookman, J. J., Toosy, A. T., Shashidhara, L. S. and White, R. A. H. (1992). The 412 retrotransposon and the development of gonadal mesoderm in Drosophila. Development 116, 1185-1192.
32. Heuer J. G., Li, K. and Kaufman, T. C. (1995). The Drosophila homeotic target gene centrosomin encodes a novel protein with leucine zippers and maps to a genomic region required for midgut morphogenesis. Development 121, 3861-3876.
33. Li, K. and Kaufman, T. C. (1996). The homeotic target gene centrosomin encodes an essential centrosomal component. Cell 85, 585-596.
34. Graba, Y. et al. (1995). DWnt-4, a new Drosophila Wnt gene acts downstream homeotic complex genes in the visceral mesoderm. Development 121, 209-218.
35. Kimble, M., Dettman, R.,W. and Raff, E. C. (1990). The ß3 tubulin gene of Drosophila melanogaster is essential for viability and fertility. Genetics 126, 991-1005.
36. Meadows, L. A., Gell, D., Broadie, K., Gould, A. P. and White, R. A. H. (1994). The cell adhesion molecule Connectin and the development of the Drosophila neuromuscular systhem. J. Cell Sci. 107, 321-328.
37. Nose, A., Mahajan, V. B. and Goodman, C. S. (1992). Connectin : A homophilic cell adhesion molecule expressed in a subset of muscles and the motoneurons that innervate them in Drosophila. Cell 70, 553-567.
38. Nose, A., Takeichi, M. and Goodman, C. S. (1994). Ectopic expression of connectin reveals a repulsive function during growth cone guidance and synapse formation. Neuron 13, 525-539.
39. Andrew, D. and Scott, M. P. (1992). Downstream of the homeotic genes. The New Biologist 4, 5-15.
40. Baker, N. E., Mlodzik, M. and Rubin, G. M. (1990). Spacing differentiation in the developing Drosophila eye: A fibrinogen-related lateral inhibitor encoded by scabrous. Science 250, 1370-1377.
41. Miyamoto, H. et al. (1995). canoe encodes a novel protein containing a GLGF/DHR motif and functions with Notch and scabrous in common developmental pathways in Drosophila. Genes Dev. 9, 612-25.
42. Mathies, L. D., Kerridge, S. and Scott, M. P. (1994). Role of the teashirt gene in Drosophila midgut morphogenesis: secreted proteins mediate the action of homeotic genes. Development 120, 2799-2809.
43. Tremml, G. and Bienz, M. (1989). Homeotic gene expression in the visceral mesoderm of Drosophila embryos. EMBO J. 8, 2677-85.
44. Thüringer, F., Cohen, S. M. and Bienz, M. (1993). Dissection of an indirect autoregulatory response of a homeotic Drosophila gene. EMBO J. 12, 2419-2430.
45. Hursh, D. A., Padgett, R. W. and Gelbart, W. (1993). Cross regulation of decapentaplegic and Ultrabithorax transcription in the embryonic visceral mesoderm of Drosophila. Development 117, 1211-1222.
46. Xiang, Y., Hoppler, S., Eresh, S. and Bienz, M. (1996). decapentaplegic, a target gene of the Wingless signalling pathway in the Drosophila midgut. Development 122, 849-858.
47. Hoppler, S. and Bienz, M. (1994). Specification of a single cell type by a Drosophila homeotic gene. Cell 76, 689-702.
48. Hoppler, S. and Bienz, M. (1995). Two different threshold of Wingless signalling with distinct developmental consequences in the Drosophila midgut. EMBO J. 14, 5016-5026.
49. Mann R. S. and Abu-Shaar, M. (1996). Nuclear import of the homeodomain protein Extradenticle in response to Wg and Dpp signalling. Nature 383, 630-633.
50. Mann, R. S. and Chan, S. K. (1996). Extra specificity from extradenticle: the partnership between Hox and PBX/EXD homeodomain proteins. Trends Genet. 12, 258-262.
51. Orlando , V. and Paro, R. (1995). Chromatin multiprotein complexes involved in the maintenance of transcription patterns. Curr. Opin. Genet. Dev. 5, 174-179.
52. Garzino, V. et al. (1992). Cell lineage specific expression of modulo, a dose-dependent modifier of variegation in Drosophila. EMBO J. 11, 4471-4479.
53. Walter, J., Dever, C. A. and Biggin, M. D. (1994). Two homeodomain proteins bind with similar specificity to a wide range of DNA sites in Drosophila embryo. Genes Dev. 8, 1678-1692.
54. Appel, B. and Sakonju, S. (1993). Cell-type-specific mechanisms of transcriptional repression by the homeotic gene products Ubx and Abd-A in Drosophila embryos. EMBO J. 12, 1099-1109.
55. Michelson, M. (1994). Muscle pattern diversification in Drosophila is determined by the autonomous function of homeotic genes in the embryonic mesoderm Development 120, 755-768.
56. Casares, F., Calleja, M. and Sanchez-Herrero, E. (1996) Functional similarity in appendage specification by the Ultrabithorax and abdominal-A Hox genes. EMBO J. 15, 3934-3942.
57. Duboule, D. and Morata, G. (1994). Colinearity and functional hierarchy among genes of the homeotic complexes. Trends Genet. 10, 358-364.
58. Struhl, G. (1983). Role of the esc gene product in ensuring the selective expression of segment specific homeotic genes in Drosophila. J. Embryol. exp. Morph. 76, 297-331.
59. Lamka, M. L., Boulet, A. M. and Sakonju, S. (1992). Ectopic expression of Ubx and Abd-B proteins during Drosophila embryogenesis: competition, not a functional hierarchy, explains phenotypic suppression. Development 116, 841-854.
60. Pellerin, I., Schnabel, C., Catron, K. M. and Abate, C. (1994). Hox proteins have different affinities for a consensus DNA site that correlate with the position of their genes on the Hox cluster. Mol. Cell. Biol. 14, 4532-4545.
61. Rauskolb, C. and Wieschaus, E. (1994). Coordinate regulation of downstream genes by extradenticle and a homeotic selector proteins. EMBO J. 13, 3561-3569.
62. Chan, S. K., Jaffe, L., Capovilla, M., Botas, J. and Mann, R. S. (1994). The DNA-binding specificity of Ultrabithorax is modulated by cooperative interactions with Extradenticle, another homeoprotein. Cell 78, 603-615.
63. Pöpperl, H. et al. (1995). Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon Exd/Pbx. Cell 81, 1031-1042.
64. Chan, S. K., Pöpperl, H., Krumlauf, R. and Mann, R. S. (1996). An Extradenticle induced conformational change in a Hox protein overcomes an inhibitory function of the conserved hexapeptide motif. EMBO J. 15, 2476-2487.
65. Van Dijk, M. A. and Murre, C. (1994). Extradenicle raises the DNA-binding specificity of homeotic selector gene products. Cell 78, 617-624.
66. Chan, S. K. and Mann, R. S. (1996). A structural model for a homeotic protein-extradenticle-DNA complex accounts for the choice of Hox protein in the heterodimer. Proc. Natl Acad. Sci. USA 93, 5223-5228.
67. Manak, J. R., Mathies, L. D. and Scott, M. P. (1994). Regulation of a decapentaplegic midgut enhancer by homeotic proteins. Development 120, 3605-3619.
68. Simeone, A. M., Gulisano, M., Acampora, A., Stornaiuolo, A., Rambaldi, M. and Boncinelli, E. (1992). Two vertebrate homeobox genes related to the Drosophila empty spiracles gene are expressed in the embryonic cerebral cortex. EMBO. J. 11, 2541-2550.
69. Carroll, S. B. (1994). Developmental regulatory mechanisms in the evolution of insect diversity. Development Supplement, 217-223.
70. Burke, A. C., Nelson, C. E., Morgan, B. A. and Tabin, C. (1995). Hox genes and the evolution of vertebrate morphology. Development 121, 333-346.
71. Kuhn, D. T. and Cunningham, G. M. (1977). Aldehyde oxydase distribution in haltere discs in homeotic bithorax mutants in Drosophila melanogaster. Mol. Gen. Genet. 150, 37-42.
72. Kuhn, D. T. and Cunningham, G. M. (1986). Isocitrate dehydrogenase in Drosophila melanogaster imaginai discs: pattern development and alteration by homeotic mutant genes. Dev. Genet. 7, 21-34.