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Volumn 124, Issue 10, 1997, Pages 2007-2014

Switching the in vivo specificity of a minimal Hox-responsive element

Author keywords

Cooperative binding; Drosophila; Extradenticle; Homeotic genes; Mouse; pbx

Indexed keywords

HOMEODOMAIN PROTEIN;

EID: 0030986189     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (86)

References (54)
  • 2
    • 0025641658 scopus 로고
    • An autoregulatory enhancer element of the Drosophila homeotic gene Deformed
    • Bergson, C. and McGinnis, W. (1990). An autoregulatory enhancer element of the Drosophila homeotic gene Deformed. EMBO J. 9, 4287-97.
    • (1990) EMBO J. , vol.9 , pp. 4287-4297
    • Bergson, C.1    McGinnis, W.2
  • 3
    • 0027332558 scopus 로고
    • Control of morphogenesis and differentiation by HOM/Hox genes
    • Botas, J. (1993). Control of morphogenesis and differentiation by HOM/Hox genes. Curr. Op. Cell. Biol. 5, 1015-1022.
    • (1993) Curr. Op. Cell. Biol. , vol.5 , pp. 1015-1022
    • Botas, J.1
  • 4
    • 0000071294 scopus 로고
    • A comprehensive classification of homeobox genes
    • (ed. D. Duboule), Oxford, UK: Oxford University Press
    • Burglin, T. (1994). A comprehensive classification of homeobox genes. In Guidebook to the Homeobox Genes (ed. D. Duboule), pp. 26-71. Oxford, UK: Oxford University Press.
    • (1994) Guidebook to the Homeobox Genes , pp. 26-71
    • Burglin, T.1
  • 5
    • 0027966927 scopus 로고
    • The DNA binding specificity of Ultrabithorax is modulated by cooperative interactions with extradenticle, another homeoprotein
    • Chan, S.-K., Jaffe, L., Capovilla, M., Botas, J. and Mann, R. S. (1994). The DNA binding specificity of Ultrabithorax is modulated by cooperative interactions with extradenticle, another homeoprotein. Cell 78, 603-615.
    • (1994) Cell , vol.78 , pp. 603-615
    • Chan, S.-K.1    Jaffe, L.2    Capovilla, M.3    Botas, J.4    Mann, R.S.5
  • 6
    • 0027191867 scopus 로고
    • The segment identity functions of Ultrabithorax are contained within its homeo domain and carboxy-terminal sequences
    • Chan, S.-K. and Mann, R. S. (1993). The segment identity functions of Ultrabithorax are contained within its homeo domain and carboxy-terminal sequences. Genes Dev. 7, 796-811.
    • (1993) Genes Dev. , vol.7 , pp. 796-811
    • Chan, S.-K.1    Mann, R.S.2
  • 7
    • 0029890916 scopus 로고    scopus 로고
    • A structural model for an extradenticle-HOX-DNA complex accounts for the choice of HOX protein in the heterodimer
    • Chan, S.-K. and Mann, R. S. (1996). A structural model for an extradenticle-HOX-DNA complex accounts for the choice of HOX protein in the heterodimer. Proc. Natl. Acad. Sci. USA 93, 5223-5228.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 5223-5228
    • Chan, S.-K.1    Mann, R.S.2
  • 8
    • 0029925624 scopus 로고    scopus 로고
    • An extradenticle-induced conformational change in a HOX protein overcomes an inhibitory function of the conserved hexapeptide motif
    • Chan, S.-K., Pöpperl, H., Krumlauf, R. and Mann, R. S. (1996). An extradenticle-induced conformational change in a HOX protein overcomes an inhibitory function of the conserved hexapeptide motif. EMBO J. 15, 2477-2488.
    • (1996) EMBO J. , vol.15 , pp. 2477-2488
    • Chan, S.-K.1    Pöpperl, H.2    Krumlauf, R.3    Mann, R.S.4
  • 9
    • 0029939199 scopus 로고    scopus 로고
    • Pbx modulation of Hox homeodomain amino-terminal arms establishes different DNA-binding specificities across the HOX locus
    • Chang, C.-P., Brocchieri, L., Shen, W.-F., Largman, C. and Cleary, M. (1996). Pbx modulation of Hox homeodomain amino-terminal arms establishes different DNA-binding specificities across the HOX locus. Mol. Cell Biol. 16, 1734-1745.
    • (1996) Mol. Cell Biol. , vol.16 , pp. 1734-1745
    • Chang, C.-P.1    Brocchieri, L.2    Shen, W.-F.3    Largman, C.4    Cleary, M.5
  • 10
    • 0028947525 scopus 로고
    • Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox Proteins
    • Chang, C.-P., Shen, W.-F., Rozenfeld, S., Lawrence, H. J., Largman, C. and Cleary, M. (1995). Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox Proteins. Genes Dev. 9, 663-674.
    • (1995) Genes Dev. , vol.9 , pp. 663-674
    • Chang, C.-P.1    Shen, W.-F.2    Rozenfeld, S.3    Lawrence, H.J.4    Largman, C.5    Cleary, M.6
  • 11
    • 0026320440 scopus 로고
    • Control of expression of the homeotic labial (lab) locus of Drosophila melanogaster: Evidence for both positive and negative autogenous regulation
    • Chouinard, S. and Kaufman, T. C. (1991). Control of expression of the homeotic labial (lab) locus of Drosophila melanogaster: evidence for both positive and negative autogenous regulation. Development 113, 1267-1280.
    • (1991) Development , vol.113 , pp. 1267-1280
    • Chouinard, S.1    Kaufman, T.C.2
  • 12
    • 0023729682 scopus 로고
    • The sequence specificity of homeodomain-DNA interaction
    • Desplan, C., Theis, J. and O'Farrell, P. H. (1988). The sequence specificity of homeodomain-DNA interaction. Cell 54, 1081-90.
    • (1988) Cell , vol.54 , pp. 1081-1090
    • Desplan, C.1    Theis, J.2    O'Farrell, P.H.3
  • 13
    • 0026660342 scopus 로고
    • Differential DNA sequence recognition is a determinant of specificity in homeotic gene action
    • Ekker, S., von Kessler, D. and Beachy, P. (1992). Differential DNA sequence recognition is a determinant of specificity in homeotic gene action. EMBO J. 11, 4059-4072.
    • (1992) EMBO J. , vol.11 , pp. 4059-4072
    • Ekker, S.1    Von Kessler, D.2    Beachy, P.3
  • 14
    • 0027936793 scopus 로고
    • The degree of variation in DNA sequence recognition among four Drosophila homeotic proteins
    • Ekker, S. C., Jackson, D. G., von Kessler, D. P., Sun, B. I., Young, K. E. and Beachy, P. A. (1994). The degree of variation in DNA sequence recognition among four Drosophila homeotic proteins. EMBO J. 13, 3551-3560.
    • (1994) EMBO J. , vol.13 , pp. 3551-3560
    • Ekker, S.C.1    Jackson, D.G.2    Von Kessler, D.P.3    Sun, B.I.4    Young, K.E.5    Beachy, P.A.6
  • 15
    • 0025764309 scopus 로고
    • Optimal DNA sequence recognition by the Ultrabithorax homeodomain of Drosophila
    • Ekker, S. C., Young, K. E., von Kessler, D. P. and Beachy, P. A. (1991) Optimal DNA sequence recognition by the Ultrabithorax homeodomain of Drosophila. EMBO J. 10, 1179-86.
    • (1991) EMBO J. , vol.10 , pp. 1179-1186
    • Ekker, S.C.1    Young, K.E.2    Von Kessler, D.P.3    Beachy, P.A.4
  • 17
    • 0000608460 scopus 로고
    • Genetic control of wing disc development in Drosophila
    • (ed. S. Brenner), pp. ?? Associated Scientific Publishers, New York
    • Garcia-Bellido, A. (1975). Genetic control of wing disc development in Drosophila. In Cell Patterning, Ciba Found Symp. (ed. S. Brenner), pp. ?? Associated Scientific Publishers, New York.
    • (1975) Cell Patterning, Ciba Found Symp.
    • Garcia-Bellido, A.1
  • 19
    • 0029053799 scopus 로고
    • Control of Drosophila adult pattern by extradenticle
    • Gonzalez-Crespo, S. and Morata, G. (1995). Control of Drosophila adult pattern by extradenticle. Development 121, 2117-2125.
    • (1995) Development , vol.121 , pp. 2117-2125
    • Gonzalez-Crespo, S.1    Morata, G.2
  • 20
    • 0031003129 scopus 로고    scopus 로고
    • Positive cross-regulation and enhancer sharing: Two mechanisms for specifying overlapping Hox expression patterns
    • Gould, A., Morrison, A., Sproat, G., White, R. and Krumlauf, R. (1997). Positive cross-regulation and enhancer sharing: two mechanisms for specifying overlapping Hox expression patterns. Genes Dev. 11, 900-913.
    • (1997) Genes Dev. , vol.11 , pp. 900-913
    • Gould, A.1    Morrison, A.2    Sproat, G.3    White, R.4    Krumlauf, R.5
  • 21
    • 0027527069 scopus 로고
    • Yeast a1 and alpha 2 homeodomain proteins form a DNA-binding activity with properties distinct from those of either protein
    • Goutte, C. and Johnson, A. D. (1993). Yeast a1 and alpha 2 homeodomain proteins form a DNA-binding activity with properties distinct from those of either protein. J. Mol. Biol. 233, 359-71.
    • (1993) J. Mol. Biol. , vol.233 , pp. 359-371
    • Goutte, C.1    Johnson, A.D.2
  • 22
    • 0028325785 scopus 로고
    • Recognition of a DNA operator by a dimer composed of two different homeodomain proteins
    • Goutte, C. and Johnson, A. D. (1994). Recognition of a DNA operator by a dimer composed of two different homeodomain proteins. EMBO J. 13, 1434-42.
    • (1994) EMBO J. , vol.13 , pp. 1434-1442
    • Goutte, C.1    Johnson, A.D.2
  • 23
    • 0029986957 scopus 로고    scopus 로고
    • DEAF-1, a novel protein that binds an essential region in a Deformed response element
    • Gross, C. T. and McGinnis, W. (1996). DEAF-1, a novel protein that binds an essential region in a Deformed response element. EMBO J. 15, 1961-70.
    • (1996) EMBO J. , vol.15 , pp. 1961-1970
    • Gross, C.T.1    McGinnis, W.2
  • 24
    • 0028978186 scopus 로고
    • A screen for modifiers of Deformed function in Drosophila
    • Harding, K. W., Gellon, G., McGinnis, N. and McGinnis, W. (1995) A screen for modifiers of Deformed function in Drosophila. Genetics 140, 1339-52.
    • (1995) Genetics , vol.140 , pp. 1339-1352
    • Harding, K.W.1    Gellon, G.2    McGinnis, N.3    McGinnis, W.4
  • 25
    • 0024298689 scopus 로고
    • Divergent homeo box proteins recognize similar DNA sequences in Drosophila
    • Hoey, T. and Levine, M. (1988). Divergent homeo box proteins recognize similar DNA sequences in Drosophila. Nature 332, 858-861.
    • (1988) Nature , vol.332 , pp. 858-861
    • Hoey, T.1    Levine, M.2
  • 26
    • 0027453705 scopus 로고
    • A universal target sequence is bound in vitro by diverse homeodomains
    • Kalionis, B. and O'Farrell, P. H. (1993). A universal target sequence is bound in vitro by diverse homeodomains. Mech. Dev. 43, 57-70.
    • (1993) Mech. Dev. , vol.43 , pp. 57-70
    • Kalionis, B.1    O'Farrell, P.H.2
  • 27
    • 0024277945 scopus 로고
    • Autoregulation of a Drosophila homeotic selector gene
    • Kuziora, M. A. and McGinnis, W. (1988). Autoregulation of a Drosophila homeotic selector gene. Cell 55, 477-85.
    • (1988) Cell , vol.55 , pp. 477-485
    • Kuziora, M.A.1    McGinnis, W.2
  • 28
    • 0026321622 scopus 로고
    • DNA binding specificity of homeodomains
    • Laughon, A. (1991). DNA binding specificity of homeodomains. Biochemistry 30, 11357-67.
    • (1991) Biochemistry , vol.30 , pp. 11357-11367
    • Laughon, A.1
  • 29
    • 0029052595 scopus 로고
    • Deformed expression in the Drosophila central nervous system is controlled by an autoactivated intronic enhancer
    • Lou, L., Bergson, C. and McGinnis, W. (1995). Deformed expression in the Drosophila central nervous system is controlled by an autoactivated intronic enhancer. Nucl. Acids Res. 23, 3481-7.
    • (1995) Nucl. Acids Res. , vol.23 , pp. 3481-3487
    • Lou, L.1    Bergson, C.2    McGinnis, W.3
  • 30
    • 0029966661 scopus 로고    scopus 로고
    • Structural determinants of Pbx1 mediating cooperative DNA-binding with pentapeptide-containing HOX proteins
    • Lu, Q. and Kamps, M. (1996). Structural determinants of Pbx1 mediating cooperative DNA-binding with pentapeptide-containing HOX proteins. Mol. Cell Biol. 16, 1632-1640.
    • (1996) Mol. Cell Biol. , vol.16 , pp. 1632-1640
    • Lu, Q.1    Kamps, M.2
  • 31
    • 0029054140 scopus 로고
    • Both Pbx1 and E2A-Pbx1 bind the DNA m,otif ATCAATCAA cooperatively with the products of multiple murine Hox genes, some of which are themselves oncogenes
    • Lu, Q., Knoepfler, P., Scheele, J., Wright, D. and Kamps, M. (1995). Both Pbx1 and E2A-Pbx1 bind the DNA m,otif ATCAATCAA cooperatively with the products of multiple murine Hox genes, some of which are themselves oncogenes. Mol. Cell Biol. 15, 3786-3795.
    • (1995) Mol. Cell Biol. , vol.15 , pp. 3786-3795
    • Lu, Q.1    Knoepfler, P.2    Scheele, J.3    Wright, D.4    Kamps, M.5
  • 32
    • 0029955433 scopus 로고    scopus 로고
    • Nuclear import of the homeodomain protein Extradenticle in response to Decapentaplegic and Wingless signalling
    • Mann, R. and Abu-Shaar, M. (1996). Nuclear import of the homeodomain protein Extradenticle in response to Decapentaplegic and Wingless signalling. Nature 383, 630-633.
    • (1996) Nature , vol.383 , pp. 630-633
    • Mann, R.1    Abu-Shaar, M.2
  • 33
    • 0029379593 scopus 로고
    • The specificity of homeotic gene function
    • Mann, R. S. (1995). The specificity of homeotic gene function. BioEssays 17, 855-863.
    • (1995) BioEssays , vol.17 , pp. 855-863
    • Mann, R.S.1
  • 34
    • 0029898760 scopus 로고    scopus 로고
    • Extra specificity from extradenticle: The partnership between HOX and exd/pbx homeodomain proteins
    • Mann, R. S. and Chan, S.-K. (1996). Extra specificity from extradenticle: The partnership between HOX and exd/pbx homeodomain proteins. Trends Genet. 12, 258-262.
    • (1996) Trends Genet. , vol.12 , pp. 258-262
    • Mann, R.S.1    Chan, S.-K.2
  • 35
    • 0026504525 scopus 로고
    • Homeobox genes and axial patterning
    • McGinnis, W. and Krumlauf, R. (1992). Homeobox genes and axial patterning. Cell 68, 283-302.
    • (1992) Cell , vol.68 , pp. 283-302
    • McGinnis, W.1    Krumlauf, R.2
  • 37
    • 0025365228 scopus 로고
    • Mutations in the Drosophila gene extradenticle affect the way specific homeo domain proteins regulate segmental identity
    • Peifer, M. and Wieschaus, E. (1990). Mutations in the Drosophila gene extradenticle affect the way specific homeo domain proteins regulate segmental identity. Genes Dev. 4, 1209-1223.
    • (1990) Genes Dev. , vol.4 , pp. 1209-1223
    • Peifer, M.1    Wieschaus, E.2
  • 38
    • 0030035691 scopus 로고    scopus 로고
    • Engrailed and Hox homeodomain proteins contain a related Pbx interaction motif that recognizes a common structure present in Pbx
    • Peltenburg, L. T. C. and Murre, C. (1996). Engrailed and Hox homeodomain proteins contain a related Pbx interaction motif that recognizes a common structure present in Pbx. EMBO J. 15, 3385-3393.
    • (1996) EMBO J. , vol.15 , pp. 3385-3393
    • Peltenburg, L.T.C.1    Murre, C.2
  • 39
    • 0029008293 scopus 로고
    • Cooperative interactions between HOX and PBX proteins mediated by a conserved peptide motif
    • Phelan, M. L., Rambaldi, I. and Featherstone, M. (1995). Cooperative interactions between HOX and PBX proteins mediated by a conserved peptide motif. Mol. Cell Biol. 15, 3989-3997.
    • (1995) Mol. Cell Biol. , vol.15 , pp. 3989-3997
    • Phelan, M.L.1    Rambaldi, I.2    Featherstone, M.3
  • 40
    • 0029055810 scopus 로고
    • Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/Pbx
    • Pöpperl, H., Bienz, M., Studer, M., Chan, S.-K., Aparicio, S., Brenner, S., Mann, R. and Krumlauf, R. (1995). Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/Pbx. Cell 81, 1031-1042.
    • (1995) Cell , vol.81 , pp. 1031-1042
    • Pöpperl, H.1    Bienz, M.2    Studer, M.3    Chan, S.-K.4    Aparicio, S.5    Brenner, S.6    Mann, R.7    Krumlauf, R.8
  • 41
    • 0026768070 scopus 로고
    • An autoregulatory element of the murine Hox-4.2 gene
    • Pöpperl, H. and Featherstone, M. S. (1992). An autoregulatory element of the murine Hox-4.2 gene. EMBO J. 11, 3673-3680.
    • (1992) EMBO J. , vol.11 , pp. 3673-3680
    • Pöpperl, H.1    Featherstone, M.S.2
  • 42
    • 0027519720 scopus 로고
    • Extradenticle, a regulator of homeotic gene activity, is a homolog of the homeobox-containing human proto-oncogene pbx1
    • Rauskolb, C., Peifer, M. and Wieschaus, E. (1993). extradenticle, a regulator of homeotic gene activity, is a homolog of the homeobox-containing human proto-oncogene pbx1. Cell 74, 1-20.
    • (1993) Cell , vol.74 , pp. 1-20
    • Rauskolb, C.1    Peifer, M.2    Wieschaus, E.3
  • 43
    • 0028858251 scopus 로고
    • Extradenticle determines segmental identities throughout development
    • Rauskolb, C., Smith, K., Peifer, M. and Wieschaus, E. (1995). extradenticle determines segmental identities throughout development. Development 121, 3663-3671.
    • (1995) Development , vol.121 , pp. 3663-3671
    • Rauskolb, C.1    Smith, K.2    Peifer, M.3    Wieschaus, E.4
  • 44
    • 0027934301 scopus 로고
    • Coordinate regulation of downstream genes by extradenticle and the homeotic selector proteins
    • Rauskolb, C. and Wieschaus, E. (1994). Coordinate regulation of downstream genes by extradenticle and the homeotic selector proteins. EMBO J. 13, 3561-3569.
    • (1994) EMBO J. , vol.13 , pp. 3561-3569
    • Rauskolb, C.1    Wieschaus, E.2
  • 45
    • 0025975559 scopus 로고
    • High-affinity binding sites for the Deformed protein are required for the function of an autoregulatory enhancer of the Deformed gene
    • Regulski, M., Dessain, S., McGinnis, N. and McGinnis, W. (1991). High-affinity binding sites for the Deformed protein are required for the function of an autoregulatory enhancer of the Deformed gene. Genes Dev. 5, 278-286.
    • (1991) Genes Dev. , vol.5 , pp. 278-286
    • Regulski, M.1    Dessain, S.2    McGinnis, N.3    McGinnis, W.4
  • 47
    • 0026489666 scopus 로고
    • Induction of labial expression in the Drosophila endoderm: Response elements for dpp signalling and for autoregulation
    • Tremml, G. and Bienz, M. (1992). Induction of labial expression in the Drosophila endoderm: response elements for dpp signalling and for autoregulation. Development 116, 447-456.
    • (1992) Development , vol.116 , pp. 447-456
    • Tremml, G.1    Bienz, M.2
  • 48
    • 0028169993 scopus 로고
    • Extradenticle raises the DNA binding specificity of homeotic selector gene products
    • van Dijk, M. and Murre, C. (1994). extradenticle raises the DNA binding specificity of homeotic selector gene products. Cell 78, 617-624.
    • (1994) Cell , vol.78 , pp. 617-624
    • Van Dijk, M.1    Murre, C.2
  • 49
    • 0025325446 scopus 로고
    • A synthetic homeodomain binding site acts as a cell type specific, promoter specific enhancer in Drosophila embryos
    • Vincent, J. P., Kassis, J. A. and O'Farrell, P. H. (1990). A synthetic homeodomain binding site acts as a cell type specific, promoter specific enhancer in Drosophila embryos. EMBO J. 9, 2573-2578.
    • (1990) EMBO J. , vol.9 , pp. 2573-2578
    • Vincent, J.P.1    Kassis, J.A.2    O'Farrell, P.H.3
  • 50
    • 0024430616 scopus 로고
    • Segmental expression of Hox-2 homoeobox-containing genes in the developing mouse hindbrain
    • Wilkinson, D. G., Bhatt, S., Cook, M., Boncinelli, E. and Krumlauf, R. (1989). Segmental expression of Hox-2 homoeobox-containing genes in the developing mouse hindbrain. Nature 341, 405-9.
    • (1989) Nature , vol.341 , pp. 405-409
    • Wilkinson, D.G.1    Bhatt, S.2    Cook, M.3    Boncinelli, E.4    Krumlauf, R.5
  • 51
    • 0027100450 scopus 로고
    • Regulation of the mec-3 gene by the C. elegans homeoproteins UNC-86 and MEC-3
    • Xue, D., Finney, M., Ruvkun, G. and Chalfie, M. (1992). Regulation of the mec-3 gene by the C. elegans homeoproteins UNC-86 and MEC-3. EMBO J. 11, 4969-79.
    • (1992) EMBO J. , vol.11 , pp. 4969-4979
    • Xue, D.1    Finney, M.2    Ruvkun, G.3    Chalfie, M.4
  • 52
    • 0027892020 scopus 로고
    • Cooperative interactions between the Caenorhabditis elegans homeoproteins UNC-86 and MEC-3
    • Xue, D., Tu, Y. and Chalfie, M. (1993). Cooperative interactions between the Caenorhabditis elegans homeoproteins UNC-86 and MEC-3. Science 261, 1324-8.
    • (1993) Science , vol.261 , pp. 1324-1328
    • Xue, D.1    Tu, Y.2    Chalfie, M.3
  • 53
    • 0028278228 scopus 로고
    • Deformed protein binding sites and cofactor binding sites are required for the function of a small segment-specific regulatory element in Drosophila embryos
    • Zeng, C., Pinsonneault, J., Gellon, G., McGinnis, N. and McGinnis, W. (1994) Deformed protein binding sites and cofactor binding sites are required for the function of a small segment-specific regulatory element in Drosophila embryos. EMBO J. 13, 2362-77.
    • (1994) EMBO J. , vol.13 , pp. 2362-2377
    • Zeng, C.1    Pinsonneault, J.2    Gellon, G.3    McGinnis, N.4    McGinnis, W.5
  • 54
    • 0027288479 scopus 로고
    • Ectopic expression and function of the Antp and Scr homeotic genes: The N terminus of the homeodomian is critical to functional specificity
    • Zeng, W., Andrew, D. J., Mathies, L. D., Horner, M. A. and Scott, M. P. (1993). Ectopic expression and function of the Antp and Scr homeotic genes: the N terminus of the homeodomian is critical to functional specificity. Development 118, 339-352.
    • (1993) Development , vol.118 , pp. 339-352
    • Zeng, W.1    Andrew, D.J.2    Mathies, L.D.3    Horner, M.A.4    Scott, M.P.5


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