Expression of mouse osteocalcin transcripts, OG1 and OG2, is differently regulated in bone tissues and osteoblast cultures

Journal of Bone and Mineral Metabolism

Volumn 19, Issue 6, 2001, Pages 345-351

  Yanai, Takeshi ^a   Katagiri, Takenobu ^a   Akiyama, Shuichi ^a   Imada, Mana ^a   Yamashita, Takeyoshi ^c   Chiba, Hiroshige ^b   Takahashi, Naoyuki ^a   Suda, Tatsuo ^a  

^a SHOWA UNIVERSITY   (Japan)

^b TOKYO MEDICAL UNIVERSITY   (Japan)

^c Pharmaceutical Research Laboratory   (Japan)

Author keywords

Gene expression; Mice; Osteoblasts; Osteocalcin

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; COLLAGEN; ENZYME; ENZYME APALI; MESSENGER RNA; OSTEOCALCIN; PROTEIN OG1; PROTEIN OG2; PROTEIN ORG; RNA; UNCLASSIFIED DRUG;

AGE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE MATRIX; BONE MINERALIZATION; BONE TISSUE; CELL CULTURE; FEMALE; GENDER; GENE CLUSTER; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; MALE; MOUSE; MOUSE STRAIN; MYOBLAST; NONHUMAN; OSTEOBLAST; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA DEGRADATION;

ANIMALS; BASE SEQUENCE; BONE AND BONES; CELLS, CULTURED; DNA, COMPLEMENTARY; GENE EXPRESSION REGULATION; KIDNEY; MICE; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; OSTEOBLASTS; OSTEOCALCIN; RNA, MESSENGER; SEQUENCE ALIGNMENT; TIBIA;

EID: 0034754107     PISSN: 09148779     EISSN: None     Source Type: Journal    
DOI: 10.1007/s007740170003     Document Type: Article

References (18)

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5. Effects of warfarin on bone
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7. The mouse osteocalcin gene cluster contains three genes with two separate spatial and temporal patterns of expression
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12. Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage
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14. A PEBP2/AML-1 related factor increases osteocalcin promoter activity through its binding to an osteoblast-specific cis-acting element
15. An AML-1 consensus sequence binds an osteoblast-specific complex and transcriptionally activates the osteocalcin gene
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17. Two distinct osteoblast-specific cis-acting elements control expression of a mouse osteocalcin gene
18. Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts