Overexpression of promyelocytic leukemia protein precludes the dispersal of ND10 structures and has no effect on accumulation of infectious herpes simplex virus 1 or its proteins

Journal of Virology

Volumn 76, Issue 18, 2002, Pages 9355-9367

  Lopez, Pascal ^a   Jacob, Robert J ^a   Roizman, Bernard ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; DAXX PROTEIN; PROMYELOCYTIC LEUKEMIA PROTEIN; PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ARTICLE; CELL IMMORTALIZATION; CELL NUCLEUS; CELL STRUCTURE; CONTROLLED STUDY; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; NONHUMAN; PREPUCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SKIN FIBROBLAST; VIRUS CELL INTERACTION; VIRUS REPLICATION;

BACULOVIRIDAE; CELL NUCLEUS STRUCTURES; CELLS, CULTURED; FIBROBLASTS; HERPESVIRUS 1, HUMAN; HUMANS; IMMEDIATE-EARLY PROTEINS; MICROSCOPY, ELECTRON; NEOPLASM PROTEINS; NUCLEAR PROTEINS; SUMO-1 PROTEIN; TRANSCRIPTION FACTORS; TRANSDUCTION, GENETIC; TUMOR SUPPRESSOR PROTEINS; UBIQUITIN-PROTEIN LIGASES; VIRAL PROTEINS; VIRUS REPLICATION;

EID: 0036720433     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.76.18.9355-9367.2002     Document Type: Article

References (68)

1. Disruption of PML subnuclear domains by the acidic IE1 protein of human cytomegalovirus is mediated through interaction with PML and may modulate a RING finger-dependent cryptic transactivator function of PML
2. The herpes simplex virus I UL11 proteins are associated with cytoplasmic and nuclear membranes and with nuclear bodies of infected cells
3. RING fingers and B-boxes: Zinc-binding protein-protein interaction domains
4. The solution structure of the RING finger domain from the acute promyelocytic leukaemia proto-oncoprotein PML
5. Herpes simplex virus type 1 immediate-early protein 1CP0 and its isolated RING finger domain act as ubiquitin E3 ligases in vitro
6. Resin development for electron microscopy and analysis of embedding at low temperature
7. Herpes virus induced proteasome-dependent degradation of the nuclear bodies-associated PML and Sp100 proteins
8. Resistance to virus infection conferred by the interferon-induced promyelocytic leukemia protein
9. Adenovirus replication is coupled with the dynamic properties of the PML nuclear structure
10. Modulation of CREB binding protein function by the promyelocytic (PML) oncoprotein suggests a role for nuclear bodies in hormone signaling
11. SUMO-1 modification of the acute promyelocytic leukaemia protein PML: Implications for nuclear localisation
12. Characterization of herpes simplex virus strains differing in their effects on social behaviour of infected cells
13. ICP0 induces the accumulation of colocalizing conjugated ubiquitin
14. Specific destruction of kinetochore protein CENP-C and disruption of cell division by herpes simplex virus immediate-early protein Vmw110
15. The disruption of ND10 during herpes simplex virus infection correlates with the Vmw110- and proteasome-dependent loss of several PML isoforms
16. HSV-1 IE protein Vmw110 causes redistribution of PML
17. PML is induced by oncogenic ras and promotes premature senescence
18. A splice variant of Skp2 is retained in the cytoplasm and fails to direct cyclin D1 ubiquitination in the uterine cancer cell line SK-UT
19. Molecular cloning of a new interferon-induced PML nuclear body-associated protein
20. The interferon (IFN)-stimulated gene Sp100 promoter contains an IFN-gamma activation site and an imperfect IFN-stimulated response element which mediate type I IFN inducibility
21. Interferon-modulated expression of genes encoding the nuclear-dot-associated proteins Sp100 and promyelocytic leukemia protein (PML)
22. Effect of PML and PML-RAR on the transactivation properties and subcellular distribution of steroid hormone receptors
23. IFN enhance expression of Sp100, an autoantigen in primary biliary cirrhosis
24. Herpes simplex virus 1-infected cell protein 0 contains two E3 ubiquitin ligase sites specific for different E2 ubiquitin-conjugating enzymes
25. Structure, organization, and dynamics of promyelocytic leukemia protein nuclear bodies
26. PML is critical for ND10 formation and recruits the PML-interacting protein daxx to this nuclear structure when modified by SUMO-1
27. Interaction of herpes simplex virus 1 alpha regulatory protein ICP0 with elongation factor 18: ICP0 affects translational machinery
28. Herpes simplex virus 1 alpha regulatory protein ICP0 interacts with and stabilizes the cell cycle regulator cyclin D3
29. 3-induced PML or PML/retinoic acid receptor alpha degradation
30. Localization of nascent RNA and CREB binding protein with the PML-containing nuclear body
31. The acute promyelocytic leukaemia-associated PML gene is induced by interferon
32. Sequestration and inhibition of Daxx-mediated transcriptional repression by PML
33. PML suppresses oncogenic transformation of NIH/3T3 ceils by activated neu
34. Degradation of nucleosome-associated centromeric histone H3-like protein CENP-A induced by herpes simplex virus type 1 protein ICP0
35. Requirements for the nuclear-cytoplasmic translocation of infected-cell protein 0 of herpes simplex virus 1
36. Nuclear bodies: Multifaceted subdomains of the interchromatin space
37. Proteins associated with the promyelocytic leukemia gene product (PML)-containing nuclear body move to the nucleolus upon inhibition of proteasome-dependent protein degradation
38. Nuclear domain 10, the site of DNA virus transcription and replication
39. The nuclear location of PML, a cellular member of the C3HC4 zinc-binding domain protein family, is rearranged during herpes simplex virus infection by the C3HC4 viral protein ICP0
40. Modification of discrete nuclear domains induced by herpes simplex virus type I immediate early gene 1 product (ICP0)
41. Review: Properties and assembly mechanisms of ND10, PML bodies, or PODs
42. PML, a growth suppressor disrupted in acute promyelocytic leukemia
43. The biologic function of PML and its role in acute promyelocytic leukemia
44. Viral immediate-early proteins abrogate the modification by SUMO-1 of PML and Sp100 proteins, correlating with nuclear body disruption
45. Conjugation with the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus
46. Alphaherpesvirus proteins related to herpes simplex virus type 1 ICP0 affect cellular structures and proteins
47. Herpes simplex virus type 1 immediate-early protein vmw110 induces the proteasome-dependent degradation of the catalytic subunit of DNA-dependent protein kinase
48. PML regulates p53 acetylation and premature senescence induced by oncogenic Ras
49. PML induces a novel caspase-independent death process
50. Role and fate of PML nuclear bodies in response to interferon and viral infections
51. Herpes simplex viruses and their replication
52. Does this have a familiar RING?
53. Transcriptional induction of the PML growth suppressor gene by interferons is mediated through an ISRE and a GAS element
54. Human Daxx regulates Fas-induced apoptosis from nuclear PML oncogenic domains (PODs)
55. The promyelocytic leukemia protein interacts with Sp1 and inhibits its transactivation of the epidermal growth factor receptor promoter
56. Modulation of Fos-mediated AP-1 transcription by the promyelocytic leukemia protein
57. The infected cell protein 0 of herpes simplex virus 1 dynamically interacts with proteasomes, binds and activates the cdc34 E2 ubiquitin-conjugating enzyme, and possesses in vitro E3 ubiquitin ligase activity
58. A single amino acid substitution in the cyclin D binding domain of the infected cell protein no. 0 abrogates the neuroinvasiveness of herpes simplex virus without affecting its ability to replicate
59. Role of cyclin D3 in the biology of herpes simplex virus 1 ICPO
60. Role of PML in cell growth and the retinoic acid pathway
61. PML is essential for multiple apoptotic pathways
62. An activity specified by the osteosarcoma line U2OS can substitute functionally for ICP0, a major regulatory protein of herpes simplex virus type 1
63. CIP1/WAF1 and cyclin D proteins
64. A RA-dependent, tumour-growth suppressive transcription complex is the target of the PML-RARα and T18 oncoproteins
65. Role of SUMO-1-modified PML in nuclear body formation
66. The transcriptional role of PML and the nuclear body
67. Promyelocytic leukemia protein (PML) and Daxx participate in a novel nuclear pathway for apoptosis
68. Glycoprotein D or J delivered in trans blocks apoptosis in SK-N-SH cells induced by a herpes simplex virus I mutant lacking intact genes expressing both glycoproteins