A single amino acid substitution in the cyclin D binding domain of the infected cell protein no. 0 abrogates the neuroinvasiveness of herpes simplex virus without affecting its ability to replicate

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 14, 1999, Pages 8184-8189

  Van Sant, C ^a   Kawaguchi, Y ^a   Roizman, B ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D; VIRUS PROTEIN;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BINDING SITE; GENE MUTATION; HERPES SIMPLEX VIRUS; HUMAN; HUMAN CELL; IMMUNOBLOTTING; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; SEQUENCE ANALYSIS; VIRUS PATHOGENESIS; VIRUS RECOMBINANT; VIRUS REPLICATION; VIRUS VIRULENCE;

AMINO ACID SUBSTITUTION; ANIMALS; ASPARTIC ACID; BINDING SITES; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM; CERCOPITHECUS AETHIOPS; CODON; CONTACT INHIBITION; CYCLINS; GENOME, VIRAL; HELA CELLS; HERPESVIRUS 1, HUMAN; HUMANS; IMMEDIATE-EARLY PROTEINS; MICE; MUTAGENESIS, SITE-DIRECTED; PHOSPHORYLATION; RABBITS; RECOMBINANT PROTEINS; RECOMBINATION, GENETIC; RETINOBLASTOMA PROTEIN; SKIN; TUMOR CELLS, CULTURED; UBIQUITIN-PROTEIN LIGASES; VERO CELLS; VIRULENCE; VIRUS REPLICATION;

EID: 0033529219     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.14.8184     Document Type: Article

References (28)