Splicing and transcription-associated proteins PSF and p54nrb/NonO bind to the RNA polymerase II CTD

RNA

Volumn 8, Issue 9, 2002, Pages 1102-1111

  Emili, Andrew ^a   Shales, Michael ^a   McCracken, Susan ^a   Xie, Weijun ^a   Tucker, Philip W ^a   Kobayashi, Ryuji ^a   Blencowe, Benjamin J ^a   Ingles, C James ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

Affinity chromatography; Pre mRNA processing; Protein complexes; Transcription

Indexed keywords

RNA POLYMERASE II;

AFFINITY CHROMATOGRAPHY; ARTICLE; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; ENZYME BINDING; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; RNA PROCESSING; RNA SPLICING; RNA TRANSCRIPTION;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; HELA CELLS; HOLOENZYMES; HUMANS; MICE; MOLECULAR SEQUENCE DATA; NUCLEAR MATRIX-ASSOCIATED PROTEINS; NUCLEAR PROTEINS; OCTAMER TRANSCRIPTION FACTORS; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; RNA POLYMERASE II; RNA PRECURSORS; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA SPLICING; RNA-BINDING PROTEINS; TRANSCRIPTION, GENETIC;

BACTERIA (MICROORGANISMS); EUKARYOTA;

EID: 0036715543     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: 10.1017/S1355838202025037     Document Type: Article

References (66)

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4. The intracisternal A-particle proximal enhancer-binding protein activates transcription and is identical to the RNA- and DNA-binding protein p54nrb/NonO
5. A coactivator of pre-mRNA splicing
6. Control of elongation by RNA polymerase II
7. A unique structure at the carboxyl terminus of the largest subunit of eukaryotic RNA polymerase II
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11. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
12. Purification and cDNA cloning of HeLa cell p54nrb, a nuclear protein
13. An RNA recognition motif (RRM) is required for the localization of PTB-associated splicing factor (PSF) to subnuclear speckles
14. Promoter-dependent photocross-linking of the acidic transcriptional activator E2F-1 to the TATA-binding protein
15. Stimulatory effect of splicing factors on transcriptional elongation
16. Paraspeckles. A novel nuclear domain
17. RNA polymerase II C-terminal domain required for enhancer-driven transcription
18. A novel set of spliceosomeassociated proteins and the essential splicing factor PSF bind stably to pre-mRNA prior to catalytic step II of the splicing reaction
19. RNA polymerase II is an essential mRNA polyadenylation factor
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21. Phosphorylated RNA polymerase II stimulates pre-mRNA splicing
22. The guanylyltransferase domain of mammalian mRNA capping enzyme binds to the phosphorylated carboxyl-terminal domain of RNA polymerase II
23. Splicing factors associate with hyperphosphorylated RNA polymerase II in the absence of pre-mRNA
24. A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II
25. An RNA polymerase II holoenzyme responsive to activators
26. Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcription
27. The nonphosphorylated form of RNA polymerase II preferentially associates with the preinitiation complex
28. The snRNP-free U1A (SF-A) complex(es): Identification of the largest subunit as PSF, the polypyrimidine-tract binding protein-associated splicing factor
29. PSF is a novel corepressor that mediates its effect through Sin3A and the DNA binding domain of nuclear hormone receptors
30. 5′-capping enzymes are targeted to pre-mRNA by binding to the phosphorylated carboxy-terminal domain of RNA polymerase II
31. The C-terminal domain of RNA polymerase II couples mRNA processing to transcription
32. SRm160 splicing coactivator promotes transcript 3′-end cleavage
33. RNA polymerase II targets pre-mRNA splicing factors to transcription sites in vivo
34. The splicing factor, Prp40, binds the phosphorylated carboxyl-terminal domain of RNA polymerase II
35. A hyperphosphorylated form of the large subunit of RNA polymerase II is associated with splicing complexes and the nuclear matrix
36. The C-terminal domain of the largest subunit of RNA polymerase II and transcription initiation
37. Functional redundancy and structural polymorphism in the large subunit of RNA polymerase II
38. A mammalian RNA polymerase II holoenzyme containing all components required for promoter-specific transcription initiation
39. Identification of tyrosine-phosphorylated proteins associated with the nuclear envelope
40. Interaction of elongation factors TFIIS and elongin A with a human RNA polymerase II holoenzyme capable of promoter-specific initiation and responsive to transcriptional activators
41. Cloning and characterization of PSF, a novel pre-mRNA splicing factor
42. Growth-related changes in phosphorylation of yeast RNA polymerase II
43. A nuclear matrix protein interacts with the phosphorylated C-terminal domain of RNA polymerase II
44. The length, phosphorylation state, and primary structure of the RNA polymerase II carboxyl-terminal domain dictate interactions with mRNA capping enzymes
45. DNA binding provides a signal for phosphorylation of the RNA polymerase II heptapeptide repeats
46. A human RNA polymerase II-containing complex associated with factors necessary for spliceosome assembly
47. REF proteins mediate the export of spliced and unspliced mRNAs from the nucleus
48. RNA polymerase II C-terminal repeat influences response to transcriptional enhancer signals
49. Dynamic association of capping enzymes with transcribing RNA polymerase II
50. Isolation of three proteins that bind to mammalian RNA polymerase II
51. Pre-mRNA processing and the CTD of RNA polymerase II: The tail that wags the dog?
52. The RNA-splicing factor PSF/p54 controls DNA-topoisomerase I activity by a direct interaction
53. Purification of eukaryotic RNA polymerase 11 by immunoaffinity chromatography. Elution of active enzyme with protein stabilizing agents from a polyol-responsive monoclonal antibody
54. Polypyrimidine tract-binding protein-associated splicing factor is a negative regulator of transcriptional activity of the porcine p450scc insulin-like growth factor response element
55. The nuclear matrix protein p255 is a highly phosphorylated form of RNA polymerase II largest subunit which associates with spliceosomes
56. A human nuclear-localized chaperone that regulates dimerization, DNA binding, and transcriptional activity of bZIP proteins
57. Polypyrimidine tract binding protein antagonizes exon definition
58. Cellular adherence elicits ligand-independent activation of the Met cell-surface receptor
59. NonO, a non-POU-domain-containing, octamer-binding protein, is the mammalian homolog of Drosophila nonAdiss
60. NonO enhances the association of many DNA-binding proteins to their targets
61. Mammalian capping enzyme complements mutant Saccharomyces cerevisiae lacking mRNA guanylyltransferase and selectively binds the elongating form of RNA polymerase II
62. The C-terminal domain of the largest subunit of RNA polymerase II interacts with a novel set of serine/argininerich proteins
63. Participation of the C-terminal domain of RNA polymerase II in exon definition during pre-mRNA splicing
64. Purification and characterization of a DNA-binding heterodimer of 52 and 100 kDa from HeLa cells
65. The fate of dsRNA in the nucleus: A p54(nrb)-containing complex mediates the nuclear retention of promiscuously A-to-I edited RNAs
66. The protein Aly links pre-messenger-RNA splicing to nuclear export in metazoans