A human nuclear-localized chaperone that regulates dimerization, DNA binding, and transcriptional activity of bZIP proteins

Molecular Cell

Volumn 4, Issue 2, 1999, Pages 219-228

  Virbasius, Ching Man A ^a   Wagner, Susanne ^a   Green, Michael R ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; BZIP ENHANCING FACTOR; CHAPERONE; CHAPERONIN; DIMER; DNA; DNA BINDING PROTEIN; GLUCOCORTICOID RECEPTOR; LEUCINE ZIPPER PROTEIN; MONOMER; PEPTIDE; POLYPEPTIDE; RECOMBINANT PROTEIN; STEROID; TAX PROTEIN; THIOSULFATE SULFURTRANSFERASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL NUCLEUS; CLONE; CONTROLLED STUDY; DIMERIZATION; DNA BINDING; ESCHERICHIA COLI; HUMAN; HUMAN CELL; IN VIVO STUDY; NONHUMAN; NUCLEIC ACID PROBE; PROTEIN FOLDING; TRANSCRIPTION REGULATION; YEAST;

EID: 0033179986     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(00)80369-X     Document Type: Article

References (68)

1. Abravaya, K., Myers, M.P., Murphy, S.P., and Morimoto, R.I. (1992). The human heat shock protein hsp70 interacts with HSF, the transcription factor that regulates heat shock gene expression. Genes Dev. 6, 1153-1164.
2. Anderson, M.G., and Dynan, W.S. (1994). Quantitative studies of the effect of HTLV-I tax protein on CREB protein-DNA binding. Nucleic Acid Res. 22, 3194-3201.
3. Angel, P., and Karin, M. (1991). The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation. Biochim. Biophys. Acta 10, 129-157.
4. Baranger, A.M. (1998). Accessory factor-bZIP-DNA interactions. Curr. Opin. Chem. Biol. 2, 18-23.
5. Baranger, A.M., Palmer, C.R., Hamm, M.K., Giebler, H.A., Brauweiler, A., Nyborg, J.K., and Schepartz, A. (1995). Mechanisms of DNA-binding enhancement by the human T-cell leukemia virus transactivator tax. Nature 376, 606-608.
6. Barnabas, S., Hai, T., and Andrisani, O.M. (1997). The hepatitis B virus X protein enhances the DNA binding potential and transcription efficacy of bZIP transcription factors. J. Biol. Chem. 272, 20684-20690.
7. Bruhn, L, Munnerlyn, A., and Grosschedl, R. (1997). ALY, a context-dependent coactivator of LEF-1 and AML-1, is required for TCRα enhancer function. Genes Dev. 11, 640-653.
8. Bukau, B., and Horwich, A.L. (1998). The Hsp70 and Hsp60 chaper-one machines. Cell 92, 351-366.
9. Choy, B., and Green, M.R. (1993). Eukaryotic activators function during multiple steps of preinitiation complex assembly. Nature 366, 531-536.
10. Dignam, J.D., Lebovitz, R.M., and Roeder, R.G. (1983). Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalain nuclei. Nucleic Acids Res. 11, 1475-1489.
11. Du, W., Thanos, D., and Maniatis, T. (1993). Mechanism of transcriptional synergism between distinct virus-inducible enhancer elements. Cell 74, 887-898.
12. Ellis, R.J. (1997). Molecular chaperones: avoiding the crowd. Curr. Biol. 7, R531-R533.
13. Ellis, R.J. (1999). Molecular chaperones: pathways and networks. Curr. Biol. 9, R137-R139.
14. Ellis, R.J., and Hartl, F.U. (1999). Principles of protein folding in the cellular environment. Curr. Opin. Struct. Biol. 9, 102-110.
15. 32. Cell 69, 833-842.
16. Giniger, E., and Ptashne, M. (1987). Transcription in yeast activated by a putative amphipathic alpha helix linked to a DNA binding unit. Nature 330, 670-672.
17. Gottesman, S., Wickner, S., and Maurizi, M.R. (1997) Protein quality control: Triage by chaperones and proteases. Genes Dev. 11, 815-823.
18. Gupta, K., Anand, G., Yin, X., Grove, L., and Prochownik, E.V. (1998). Mmip1 : A novel leucine zipper protein that reverses the suppressive effects of Mad family members on c-myc. Oncogene 16, 1149-1159.
19. Hoffmann, A., and Roeder, R.G. (1991). Purification of his-tagged proteins in non-denaturing conditions suggests a convenient method for protein interaction studies. Nucleic Acids Res. 19, 6337-6338.
20. Hu, J.C., O'Shea, E.K., Kim, P.S., and Sauer, R.T. (1990). Sequence requirements for coiled-coils: Analysis with lambda repressor-GCN4 leucine zipper fusions. Science 250, 1400-1403.
21. Hurst, H.C. (1995). Transcription factors 1: bZip proteins. Protein Profile 2, 101-168.
22. Jakob, U., and Buchner, J. (1994). Assisting spontaneity: The role of Hsp90 and small Hsps as molecular chaperones. Trends Biochem. Sci. 19, 205-211.
23. Jakob, U., Gaestel, M., Engel, K., and Buchner, J. (1993). Small heat shock proteins are molecular chaperones. J. Biol. Chem. 268, 1517-1520.
24. Johnson, J.L., and Craig, E.A. (1997). Protein folding in vivo: Unraveling complex pathways. Cell 90, 201-204.
25. Kong, Y., Flick, M.J., Kudla, A.J., and Konieczny, S.F. (1997). Muscle LIM protein promotes myogenesis by enhancng the activity of MyoD. Mol. Cell. Biol. 17, 4750-4760.
26. Kouzarides, T., and Ziff, E. (1988). The role of the leucine zipper in the fos-jun interaction. Nature 336, 646-651.
27. Laminet, A.A., Ziegelhoffer, T., Georgopoulos, C., and Pluckthun, A. (1990). The Escherichia coli heat shock proteins GroEL and GroES modulate the folding of the β-lactamase precursor. EMBO J. 9, 2317-2319.
28. Lee, G.J., Pokala, N., and Vierling, E. (1995). Structure and in vitro molecular chaperone activity of cytosolic small heat shock proteins from pea. J. Biol. Chem. 270, 10432-10438.
29. Lefstin, J.A., and Yamamoto, K.R. (1998). Allosteric effects of DNA on transcriptional regulators. Nature 392, 885-888.
30. Lemaigre, F.P., Ace, C.I., and Green, M.R. (1993). The cAMP response element binding protein, CREB, is a potent inhibitor of diverse transcriptional activators. Nucleic Acid Res. 21, 2907-2911.
31. Lindquist, S., and Craig, E. (1988). The heat shock proteins. Annu. Rev. Genet. 22, 631-677.
32. Liu, F., and Green, M.R. (1990). A specific member of the ATF transcription factor family can mediate transcription activation by the adenovirus E1a protein. Cell 61, 1217-1224.
33. Liu, F., and Green, M.R. (1994). Promoter targeting by adenovirus E1a through interaction with different cellular DNA-binding domains. Nature 368, 520-525.
34. Liu, Z., Batt, B., and Carmichael, G.G. (1994). Targeted nuclear antisense RNA mimics natural antisense-induced degradation of polyoma virus early RNA. Proc. Natl. Acad. Sci. USA 91, 4258-4262.
35. McKnight, S.L. (1996). Transcription revisited: A commentary on the 1995 Cold Spring Harbour Laboratory meeting, "mechanisms of eukaryotic transcription." Genes Dev. 10, 367-381.
36. McKnight, S., and Yamamoto, K.R., eds. (1992). Transcriptional Regulation (Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press).
37. Martin, J., and Hartl, F.U. (1997). Chaperone-assisted protein folding. Curr. Opin. Struct. Biol. 7, 41-52.
38. Martin, J., Langer, T., Boteva, R., Schramel, A., Horwich, A.L., and Hartl, F.U. (1991). Chaperonin-mediated protein folding at the surface of groEL through a "molten globule"-like intermediate. Nature 352, 36-42.
39. Nathan, D.F., and Lindquist, S. (1995). Mutational analysis of Hsp90 function: Interactions with a steroid receptor and a protein kinase. Mol. Cell. Biol. 15, 3917-3925.
40. O'Neil, K.T., Shuman, J.D., Ampe, C., and DeGrado, W.F. (1991). DNA-induced increase in the alpha-helical content of C/EBP and GCN4. Biochemistry 30, 9030-9034.
41. O'Shea, E.K., Rutkowski, R., and Kim, P.S. (1989a). Evidence that the leucine zipper is a coiled coil. Science 243, 538-542.
42. O'Shea, E.K., Rutkowski, R., Stafford, W.F., 3rd, and Kim, P.S. (1989b). Preferential heterodimer formation by isolated leucine zippers from fos and jun. Science 245, 646-648.
43. O'Shea, E.K., Klemm, J.D., Kim, P.S., and Alber, T. (1991). X-ray structure of the GCN4 leucine zipper, a two-stranded, parallel coiled coil. Science 254, 539-544.
44. Ogawa, J., and Long, S.R. (1995). The Rhizobium meliloti groELc locus is required for regulation of early nod genes by the transcription activator NodD. Genes Dev. 9, 714-729.
45. Palmer, C.R., Gegnas, L.D., and Schepartz, A. (1997). Mechanism of DNA binding enhancement by hepatitis B virus protein pX. Biochemistry 36, 15349-15355.
46. Patel, L.R., Curran, T., and Kerppola, T.K. (1994). Energy transfer analysis of Fos-Jun dimerization and DNA binding. Proc. Natl. Acad. Sci. USA 91, 7360-7364.
47. Perini, G., Wagner, S., and Green, M.R. (1995). Recognition of bZIP proteins by the human T-cell leukaemia virus transactivator tax. Nature 376, 602-605.
48. Perini, G., Oetjen, E., and Green, M.R. (1999). The hepatitis B pX protein promotes dimerization and DNA binding of cellular basic region/leucine zipper proteins by targeting the conserved basic region. J. Biol. Chem. 274, 13970-13977.
49. Ransone, L.J., Visvader, J., Sassone-Corsi, P., and Verma, I.M. (1989). Fos-Jun interaction: Mutational analysis of the leucine zipper domain of both proteins. Genes Dev. 3, 770-781.
50. Rozema, D., and Gellman, S.H. (1996). Artificial chaperone-assisted refolding of carbonic anhydrase B. J. Biol. Chem. 271, 3478-3487.
51. Ruddon, R.W., and Bedows, E. (1997). Assisted protein folding. J. Biol. Chem. 272, 3125-3128.
52. Schirmer, E.C., Glover, J.R., Singer, M.A., and Lindquist, S. (1996). Hsp100/Clp proteins: A common mechanism explains diverse functions. Trends Biochem. Sci. 21, 289-296.
53. Shue, G., and Kohtz, D.S. (1994). Structural and functional aspects of basic helix-loop-helix protein folding by heat-shock protein 90. J. Biol. Chem. 269, 2707-2711.
54. Shuman, J.D., Cheong, J., and Coligan, J.E. (1997). ATF-2 and c/EBPalpha can form a heterodimeric DNA binding complex in vitro. Functional implications for transcriptional regulation. J. Biol. Chem. 272, 12793-12800.
55. Smith, D.B., and Johnson, K.S. (1988). Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase. Genes 67, 31-40.
56. Smith, S.E., Papavassiliou, A.G., and Bohmann, D. (1993). Different TRE-related elements are distinguished by sets of DNA-binding proteins with overlapping sequence specificity. Nucleic Acid Res. 21, 1581-1585.
57. Tan, S., and Richmond, T.J. (1998). Eukaryotic transcription factors. Curr. Opin. Struct. Biol. 8, 41-48.
58. Thayer, M.J., and Weintraub, H. (1993). A cellular factor stimulates the DNA-binding activity of MyoD and E47. Proc. Natl. Acad. Sci. USA 90, 6483-6487.
59. Thompson, K.S., Vinson, C.R., and Freire, E. (1993). Thermodynamic characterization of the structural stability of the coiled-coil region of the bZIP transcription factor GCN4. Biochemistry 32, 5491-5496.
60. Turner, R., and Tjian, R. (1989). Leucine repeats and an adjacent DNA binding domain mediate the formation of functional cFos-cJun heterodimers. Science 243, 1689-1694.
61. Wagner, S., and Green, M.R. (1993). HTLV-1 tax protein stimulation of DNA binding of bZIP proteins by enhancing dimerization. Science 262, 395-399.
62. Wagner, S., and Green, M.R. (1994). DNA-binding domains: Targets for viral and cellular regulators. Curr. Opin. Cell Biol. 6, 410-414.
63. Weiss, M.A., Ellenberger, T., Wobbe, C.R., Lee, J.P., Harrison, S.C., and Struhl, K. (1990). Folding transition in the DNA-binding domain of GCN4 on specific binding to DNA. Nature 347, 575-578.
64. Wiech, H., Buchner, J., Zimmermann, R., and Jakob, U. (1992). Hsp90 chaperones protein folding in vitro. Nature 358, 169-170.
65. Welsh, M.J., and Gaestel, M. (1998). Small heat-shock protein family: function in health and disease. Ann. NY Acad. Sci. 851, 28-35.
66. Yin, M.J., Paulssen, E., Seeler, J., and Gaynor, R.B. (1995). Chimeric proteins composed of jun and creb define domains required for interaction with the human T-cell leukemia virus type 1 tax protein. J. Virol. 69, 6209-6218.
67. Zhang, G., Taneja, K., Singer, R.H., and Green, M.R. (1994). Localization of pre-mRNA splicing in mammalian nuclei. Nature 372, 809-812.
68. Zhao, L.J., and Giam, C.Z. (1991). Interaction of the human T-cell lymphotrophic virus type I (HTLV-I) transcriptional activator tax with cellular factors that bind specifically to the 21-base pair repeats in the HTLV-I enhancer. Proc. Natl. Acad. Sci. USA 88, 11445-11449.