Interactions of n-3 fatty acids with ion channels in excitable tissues

Prostaglandins Leukotrienes and Essential Fatty Acids

Volumn 67, Issue 2-3, 2002, Pages 113-120

  Leaf, A ^a   Xiao, Y F ^b   Kang, J X ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINE; BINDING PROTEIN; ION CHANNEL; ION CHANNEL PROTEIN; LYSINE; OMEGA 3 FATTY ACID; SODIUM CHANNEL; UNCLASSIFIED DRUG; CALCIUM; DETERGENT;

ALPHA CHAIN; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CONFERENCE PAPER; CONFORMATIONAL TRANSITION; HUMAN; HYPOTHESIS; INHIBITION KINETICS; ION CONDUCTANCE; LIGAND BINDING; NONHUMAN; PHOSPHOLIPID BILAYER; PHOSPHOLIPID MEMBRANE; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; SODIUM CURRENT; ANIMAL; ARTICLE; CELL CULTURE; CELL MEMBRANE POTENTIAL; CHANNEL GATING; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; ELECTROPHYSIOLOGY; HEART MUSCLE CELL; LIPID BILAYER; METABOLISM; PROTEIN BINDING; RAT; TIME;

ANIMALS; CALCIUM; CELLS, CULTURED; DETERGENTS; ELECTROPHYSIOLOGY; FATTY ACIDS, OMEGA-3; ION CHANNEL GATING; ION CHANNELS; LIPID BILAYERS; MEMBRANE POTENTIALS; MYOCYTES, CARDIAC; PROTEIN BINDING; RATS; TIME FACTORS;

EID: 0036694375     PISSN: 09523278     EISSN: None     Source Type: Journal    
DOI: 10.1054/plef.2002.0407     Document Type: Conference Paper

References (29)

1. Effects of fatty acids on the ventricular arrhythmia threshold in the isolated heart of the rabbit
2. Dietary fish oil prevents ventricular fibrillation following coronary artery occlusion and reperfusion
3. Dietary lipid modulation of ventricular fibrillation threshold in the marmoset monkey
4. Relative effects of dietary saturated, monounsaturated, and polyunsaturated fatty acids on cardiac arrhythmias in rats
5. Prevention of ischemia-induced arrhythmias by n-3 fatty acids
6. Prevention of ischemia-induced cardiac sudden death by n-3 polyunsaturated fatty acids
7. Prevention of ischemia-induced cardiac sudden death by pure n-3 polyunsaturated fatty acids
8. Effects of long-chain polyunsaturated fatty acids on the contraction of neonatal rat cardiac myocytes
9. Free long-chain polyunsaturated fatty acids reduce membrane electrical excitability in neonatal rat cardiac myocytes
10. Prevention and termination of arrhythmias induced by lysophosphatidyl choline and acylcarnitine in neonatal rat cardiac myocytes by free omega-3 polyunsaturated fatty acids
11. + channels of neonatal rat ventricular myocytes
12. + channel
13. + channels
14. 2+ currents by polyunsaturated fatty acids in adult and neonatal rat cardiac myocytes
15. + channels by local anesthetics
16. + channel D4-S6 reduce inactivated channel block by local anesthetics
17. + channels
18. Lipid domains in membranes
19. Partition of polyunsaturated fatty acids, which prevent arrhythmias, into phospholipids cell membranes
20. Ion channels as tools to monitor lipid bilayer-membrane protein interactions: Gramicidin channels as molecular force transducers
21. Gramicidin channels in phospholipid bilayers with unsaturated acyl chains
22. Engineering the gramicidin channel
23. Membrane stiffness and channel function
24. Spring constants for channel-induced lipid bilayer deformations estimates using gramicidin channels
25. Lipid bilayer energy, curvature stress and assembly of gramicidin channels
26. Energetics of inclusion-induced bilayer deformations
27. Restoration of cAMP-stimulated CFTR chloride channel activity in F508 cells by deoxyspergualin
28. + channel in ferret cardiac myocytes
29. + channels by directly binding to the channel protein