Evidence that free polyunsaturated fatty acids modify Na+ channels by directly binding to the channel proteins

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 8, 1996, Pages 3542-3546

  Kang, Jing X ^a   Leaf, Alexander ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b Brockton W Roxbury Vet Aff M   (United States)

Author keywords

3 and 6 fatty acids; antiarrhythmics; cardiac myocytes; ion channel; receptor

Indexed keywords

ANTIARRHYTHMIC AGENT; BATRACHOTOXININ A 20ALPHA BENZOATE; DOCOSAHEXAENOIC ACID; ICOSAPENTAENOIC ACID; LINOLEIC ACID; LINOLENIC ACID; OLEIC ACID; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; POLYUNSATURATED FATTY ACID; RADIOLIGAND; SODIUM CHANNEL; STEARIC ACID;

ANIMAL CELL; ANTIARRHYTHMIC ACTIVITY; ARTICLE; CONTROLLED STUDY; HEART MUSCLE CELL; LIGAND BINDING; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; RAT; RECEPTOR BINDING;

ANIMALS; BATRACHOTOXINS; BINDING SITES; CATTLE; CELLS, CULTURED; FATTY ACIDS, NONESTERIFIED; MODELS, BIOLOGICAL; MYOCARDIUM; NEUROTOXINS; RADIOLIGAND ASSAY; RATS; SODIUM CHANNELS;

EID: 0029928093     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.8.3542     Document Type: Article

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