Courtship lite: A personal history of reproductive behavioral neurogenetics in Drosophila

Journal of Neurogenetics

Volumn 16, Issue 3, 2002, Pages 135-163

  Hall, Jeffrey C ^a  

^a BRANDEIS UNIVERSITY   (United States)

Author keywords

Courtship song; Insect brain; Male behavior; Mating; Mutants; Transgenics; Ventral nerve cord

Indexed keywords

COURTSHIP; CYTOGENETICS; DROSOPHILA; MATING; MOLECULAR GENETICS; MUTANT; NONHUMAN; PRIORITY JOURNAL; REPRODUCTION; REVIEW; SEX DIFFERENCE; SEXUAL BEHAVIOR; TRANSGENE; VENTRAL ROOT;

ANIMALS; COURTSHIP; DROSOPHILA; FEMALE; GENES, INSECT; MALE; MOVEMENT; MUTATION; NERVOUS SYSTEM PHYSIOLOGY; PHENOTYPE; SEXUAL BEHAVIOR, ANIMAL; SOUND; VARIATION (GENETICS); WING;

INSECTA;

EID: 0036665017     PISSN: 01677063     EISSN: None     Source Type: Journal    
DOI: 10.1080/01677060215307     Document Type: Review

References (164)

1. Allada, R., Emery, P., Takahashi, J.S., & Rosbash, M. (2001). Stopping time: The genetics of fly and mouse circadian clocks. Ann. Rev. Neurosci. 24, 1091-1119.
2. Alt, S., Ringo, J., Talyn, B., Bray, W., & Dowse, H. (1998). The period gene controls courtship song cycles in Drosophila melanogaster. Anim. Behav. 56, 87-97.
3. An, X., Armstrong, J.D., Kaiser, K., & O'Dell, K.M. (2000). The effects of ectopic white and transformer expression on Drosophila courtship behavior. J. Neurogenet. 14, 227-243.
4. Arthur, B.I. Jr., Jallon, J.-M., Caflisch, B., Choffat, Y., & Nöthiger, R. (1998). Sexual behaviour in Drosophila is irreversibly programmed during a critical period. Curr. Biol. 8, 1187-1190.
5. Baker, B.S., Taylor, B.J., & Hall, J.C. (2001). Are complex behaviors specified by dedicated regulatory genes? Reasoning from Drosophila. Cell 105, 13-24.
6. Balakireva, M., Stocker, R.F., Gendre, N., & Ferveur, J.-F. (1998). Voilà, a new Drosophila courtship variant that affects the nervous system: Behavioral, neural, and genetic characterization. J. Neurosci. 18, 4335-4343.
7. Barondes, S.H. (1993). Molecules and Mental Illness. New York: Scientific American Library.
8. Bastock, M. (1956). A gene mutation which changes behavior pattern. Evolution 10, 421-439.
9. Beaver, L.M., Gvakharia, B.O., Vollintine, T.S., Hege, D.M., Stanewsky, R., & Giebultowicz, J.M. (2002). Loss of circadian clock function decreases reproductive fitness in males of Drosophila melanogaster. Proc. Nat. Acad. Sci. USA 99, 2134-2139.
10. Begg, M., & Packman, E.M. (1951). Antennae and mating behavior in Drosophila melanogaster. Nature 168, 953.
11. Begun, D.J., Whitley, P., Todd, B.L., Waldrip-Dail, H.M., & Clark, A.G. (2000). Molecular population genetics of male accessory gland proteins in Drosophila. Genetics 156, 1879-1888.
12. Bellen, H.J., Gregory, B.K., Olsson, C.L., & Kiger, J.A. Jr. (1987). Two Drosophila learning mutants, dunce and rutabaga, provide evidence of a maternal role for cAMP on embryogenesis. Devel. Biol. 121, 432-444.
13. Bellen, H.J., & Kiger, J.A. Jr. (1987). Sexual hyperactivity and reduced longevity of dunce females of Drosophila melanogaster. Genetics 115, 153-160.
14. Bennet-Clark, H.C., & Ewing, A.W. (1969). Pulse interval as a critical parameter in the courtship song of Drosophila melanogaster. Anim. Behav. 17, 755-759.
15. Billeter, J.-C., Goodwin, S.F., & O'Dell, K.M.C. (2002). Genes mediating sex-specific behaviors in Drosophila. Adv. Genet. 47, 87-116.
16. Burnet, B., & Wilson, R. (1980). Pattern mosaicism for behavior controlled by the yellow locus in Drosophila melanogaster. Genet. Res. 36, 235-247.
17. Campbell, J.L., & Nash, H.A. (2001). Volatile general anesthetics reveal a neurobiological role for the white and brown genes of Drosophila melanogaster. J. Neurobiol. 49, 339-349.
18. Campesan, S., Dubrova, Y., Hall, J.C., & Kyriacou, C.P. (2001). The nonA gene in Drosophila conveys species-specific behavioral characteristics. Genetics 158, 1535-1543.
19. Castrillon, D.H., Gönczy, P., Alexander, S., Rawson, R., Eberhart, C.G., Viswanathan, S., DiNardo, S., & Wasserman, S.A. (1993). Toward a molecular genetic analysis of spermatogenesis in Drosophila melanogaster: Characterization of male-sterile mutants generated by single P element mutagenesis. Genetics 135, 489-505.
20. Chan, B., Villella, A., Funes, P., & Hall, J.C. (2002). Courtship and other behaviors affected by a heat-sensitive, molecularly novel mutation in the cacophony calcium-channel gene of Drosophila. Genetics 162, 135-153.
21. Chapman, T. (2001). Seminal fluid-mediated fitness traits in Drosophila. Heredity 87, 511-521.
22. Chapman, T., Choffat, Y., Lucas, W.E., Kubli, E., & Partridge, L. (1996). Lack of response to sex-peptide results in increased cost of mating in dunce Drosophila melanogaster females. J. Insect Physiol. 42, 1007-1015.
23. Chapman, T., Liddle, L.F., Kalb, J.M., Wolfner, M.F., & Partridge, L. (1995). Cost of mating in Drosophila melanogaster females is mediated by male accessory gland products. Nature 373, 241-244.
24. Christiansen, A.E., Keisman, E.L., Ahmad, S.M., & Baker, B.S. (2002). Sex comes in from the cold: the integration of sex and pattern. Trends Genet. In press.
25. Chung, Y.D., Zhu, J., Han, Y., & Kernan, M.J. (2001). nomp A encodes a PNS-specific, ZP domain protein required to connect mechanosensory dendrites to sensory structures. Neuron 29, 415-428.
26. Cobb, M., & Ferveur, J.-F. (1996). Evolution and genetic control of mate recognition and stimulation in Drosophila. Behav. Proc. 35, 35-54.
27. Cook, R., & Cook, A. (1975). The attractiveness to males of female Drosophila melanogaster: effects of mating, age and diet. Anim Behav. 23, 521-526.
28. Coschigano, K.T., & Wensink, P.C. (1993). Sex-Specific transcriptional regulation by the male and female doublesex proteins of Drosophila. Genes Devel. 7, 42-54.
29. Crossley, S.A. (1988). Failure to confirm rhythms in Drosophila courtship song. Anim. Behav. 36, 1098-1109.
30. Dellinger, B., Felling, R., & Ordway, R.W. (2000). Genetic modifiers of the Drosophila NSF mutant, comatose, include a temperature-sensitive paralytic allele of the calcium channel α1-subunit gene, cacophony. Genetics 155, 203-211.
31. Demetriades, M.C., Thackeray, J.R., & Kyriacou, C.P. (1999). Courtship song rhythms in Drosophila yakuba. Anim. Behav. 57, 379-386.
32. Dockendorff, T.C., Su, H.S., McBride, S.M., Yang, Z., Choi, C.H., Siwicki, K.K., Sehgal, A., & Jongens, T.A. (2002). Drosophila lacking dfmr1 activity show defects in circadian output and fail to maintain courtship interest. Neuron 34, 973-984.
33. Dubnau, J., & Tully, T. (1998). Gene discovery in Drosophila: New insights for learning and memory. Ann. Rev. Neurosci. 21, 407-444.
34. Dudai, Y., Jan, Y.-N., Byers, D., Quinn, W., & Benzer, S. (1976). dunce, a mutant of Drosophila deficient in learning. Proc. Nat. Acad. Sci. USA 73, 1684-1688.
35. Dunlap, J.C. (1999). Molecular bases for circadian clocks. Cell 96, 271-290.
36. Eberl, D.F., Duyk, G.M., & Perrimon, N. (1997). A genetic screen for mutations that disrupt an auditory response in Drosophila melanogaster. Proc. Nat. Acad. Sci. USA 94, 14837-14842.
37. Eberl, D.F., Hardy, R.W., & Kernan, M.J. (2000). Genetically similar transduction mechanisms for touch and hearing in Drosophila. J. Neurosci. 20, 5981-5988.
38. Ejima, A., Nakayama, S., & Aigaki, T. (2001). Phenotypic association of spontaneous ovulation and sexual receptivity in virgin females of Drosophila melanogaster mutants. Behav. Genet. 31, 437-444.
39. Ewing, A.W. (1978). The antenna of Drosophila as a 'love song' receptor. Physiol. Entomol. 3, 33-36.
40. Ewing, A.W. (1988). Cycles in the courtship song of male Drosophila melanogaster have not been demonstrated. Anim. Behav. 36, 1091-1097.
41. Ferveur, J.-F., & Greenspan, R.J. (1998). Courtship behavior of brain mosaics in Drosophila. J. Neurogenet. 12, 205-226.
42. Ferveur, J.-F., Savarit, F., O'Kane, C.J., Sureau, G., Greenspan, R.J., & Jallon, J.-M. (1997). Genetic feminization of pheromones and its behavioral consequences in Drosophila males. Science 276, 1555-1558.
43. Ferveur, J.-F., Störtkuhl, K.F., Stocker, R.F., & Greenspan, R.J. (1995). Genetic feminization of brain structures and changed sexual orientation in male Drosophila melanogaster. Science 267, 902-905.
44. Finley, K.D., Edeen, P.T., Foss, M., Gross, E., Ghbeish, N., Palmer, R.H., Taylor, B.J., & McKeown, M. (1998). dissatisfaction encodes a tailless-like nuclear receptor expressed in a subset of CNS neurons controlling Drosophila sexual behavior. Neuron 21, 1363-1374.
45. Finley, K.D., Taylor, B.J., Milstein, M., & McKeown, M. (1997). dissatisfaction, a gene involved in sex-specific behavior and neural development of Drosophila melanogaster. Proc. Nat. Acad. Sci. USA 94, 913-918.
46. Gailey, D.A., & Hall, J.C. (1989). Behavior and cytogenetics of fruitless in Drosophila melanogaster: Different courtship defects caused by separate, closely linked lesions. Genetics 121, 773-785.
47. Gailey, D.A., Hall, J.C., & Siegel, R.W. (1985). Reduced reproductive success for a conditioning mutant in experimental populations of Drosophila melanogaster. Genetics 111, 795-804.
48. Gailey, D.A., Jackson, F.R., & Siegel, R.W. (1982). Male courtship in Drosophila: The conditioned response to immature males and its genetic control. Genetics 102, 771-782.
49. Gailey, D.A., Jackson, F.R., & Siegel, R.W. (1984). Conditioning mutations in Drosophila melanogaster affect an experience-dependent behavioral modification in courting males. Genetics 106, 613-623.
50. Gailey, D.A., Taylor, B.J., & Hall, J.C. (1991). Elements of the fruitless locus regulate development of the muscle of Lawrence, a male-specific structure in the abdomen of Drosophila melanogaster adults. Development 113, 879-890.
51. Gaines, P., Tompkins, L., Woodard, C.T., & Carlson, J.R. (2000). quick-to-court, a Drosophila mutant with elevated levels of sexual behavior, is defective in a predicted coiled-coil protein. Genetics 154, 1627-1637.
52. Geer, B.W., & Green, M.M. (1962). Genotype, phenotype and mating behavior of Drosophila melanogaster. Amer. Nat. 96, 175-181.
53. Gessa, G.L., & Tagliomonte, A. (1974). Possible role of brain serotonin and dopamine in controlling male sexual behavior. In E. Costa, G.L. Gessa, & M. Sandler (Eds.), Advances in Biochemical Psycholpharacology (Vol. 11, pp. 217-228). New York: Raven Press.
54. Gill, K.S. (1963a). A mutation causing abnormal courtship and mating behavior in males of Drosophila melanogaster. Amer. Zool. 3, 507.
55. Gill, K.S. (1963b). A mutation causing abnormal mating behavior. Dros. Info. Serv. 38, 33.
56. Goodwin, S.F. (1999). Molecular neurogenetics of sexual differentiation and behaviour. Curr. Opin. Neurobiol. 9, 759-765.
57. Goodwin, S.F., Taylor, B.J., Villella, A., Foss, M., Ryner L.C., Baker, B.S., & Hall, J.C. (2000). Mutations in the fruitless gene of Drosophila melanogaster causing aberrant splicing or altered spatial distributions of fru's sex-specific expression patterns. Genetics 154, 725-745.
58. Greenspan, R.J. (1995). Flies, genes, learning, and memory. Neuron 15, 747-750.
59. Greenspan, R.J., & Ferveur, J.-F. (2000). Courtship in Drosophila. Ann. Rev. Genet. 34, 205-232.
60. Greenspan, R.J. Finn, J.A. Jr., & Hall, J.C. (1980). Acetylcholinesterase mutants in Drosophila and their effects on the structure and function of the central nervous system. J. Comp. Neurol. 189, 741-774.
61. Grosjean, Y., Balakireva, M., Dartevelle, L., & Ferveur, J.F. (2001). PGal4 excision reveals the pleiotropic effects of Voilá, a Drosophila locus that affects development and courtship behaviour. Genet. Res. 77, 239-250.
62. Grossfield, J. (1975). Behavioral mutants of Drosophila. In R.C. King (Ed.), Handbook of Genetics (Vol. 3, pp. 679-702). New York: Plenum Press.
63. Hall, J.C. (1977). Portions of the central nervous system controlling reproductive behavior in Drosophila melanogaster. Behav. Genet. 7, 291-312.
64. Hall, J.C. (1978). Courtship among males due to a male-sterile mutation in Drosophila melanogaster. Behav. Genet. 8, 125-141.
65. Hall, J.C. (1979). Control of male reproductive behavior by the central nervous system of Drosophila: Dissection of a courtship pathway by genetic mosaics. Genetics 92, 437-457.
66. Hall, J.C. (1994). The mating of a fly. Science 264, 1702-1714.
67. Hall, J.C. (1996). Drosophila mating, genetic basis of. In R. Meyers (Ed.), Encylopedia of Molecular Biology: Fundamentals and Applications. (pp. 130-146). Weinheim, Germany: VCH Publishers.
68. Hall, J.C., & Kankel, D.R. (1976). Genetics of acetylcholinesterase in Drosophila melanogaster. Genetics 83, 517-533.
69. Hall, J.C., Kulkarni, S.J., Kyriacou, C.P., Yu, Q., & Rosbash, M. (1990). Genetic and molecular analysis of neural development and behavior in Drosophila. In M.E. Hahn, J.K. Hewitt, N.D. Henderson, & R. Benno (Eds.), Developmental Behavior Genetics. (pp. 100-112). New York: Oxford University Press.
70. Hall, J.C., & Kyriacou, C.P. (1990). Genetics of biological rhythms in Drosophila. Adv. Insect Physiol. 22, 221-298.
71. Heifetz, Y., Lung, O., Frongillo, E.A. Jr., & Wolfner, M.F. (2000). The Drosophila seminal fluid protein Acp26Aa stimulates release of oocytes by the ovary. Curr. Biol. 10, 99-102.
72. Heimbeck, G., Bugnon, V., Gendre, N., Keller, A., & Stocker, R.F. (2001). A central neural circuit for experience-independent olfactory and courtship behavior in Drosophila melanogaster. Proc. Nat. Acad. Sci. USA 98, 15336-15341.
73. Hing, A., & Carlson, J.R. (1996). Male-male courtship behavior induced by ectopic expression of the Drosophila white gene: Role of sensory function and age. J. Neurobiol. 30, 454-464.
74. Homyk, T. Jr., & Pye, Q. (1989). Some mutations affecting neural or muscular tissues alter the physiological components of the electroretinogram in Drosophila. J. Neurogenet. 5, 37-48.
75. Ito, H., Fujitani, K., Usui, K., Shimizu-Nishikawa, K., Tanaka, S., & Yamamoto, D. (1996). Sexual orientation in Drosophila is altered by the satori mutation in the sexdetermination gene fruitless that encodes a zinc finger protein with a BTB domain. Proc. Nat. Acad. Sci. USA 93, 9687-9692.
76. Joiner, M.-I.A., & Griffith, L.C. (1997). CaM kinase II and visual input modulate memory formation in the neuronal circuit controlling courtship conditioning. J. Neurosci. 17, 9384-9391.
77. Joiner, M.-I.A., & Griffith, L.C. (1999). Mapping of the anatomical circuit of CaM kinasedependent courtship conditioning in Drosophila. Learn. Mem. 6, 177-192.
78. Joiner, M.-I.A., & Griffith, L.C. (2000). Visual input regulates circuit configuration in courtship conditioning of Drosophila melanogaster. Learn. Mem. 7, 32-42.
79. Kalb, J.M., DiBenedetto, A.J., & Wolfner, M.F. (1993). Probing the function of Drosophila melanogaster accessory glands by directed cell ablation. Proc. Nat. Acad. Sci. USA 90, 8093-8097.
80. Kane, N.S., Robichon, A., Dickinson, J.A., & Greenspan, R.J. (1997). Learning without performance in PKC-deficient Drosophila. Neuron 18, 307-314.
81. Kerr, C., Ringo, J., Dowse, H., & Johnson, E. (1997). icebox, a recessive X-linked mutation in Drosophila causing low sexual receptivity. J. Neurogenet. 11, 213-229.
82. Klarsfeld, A., & Rouyer, F. (1998). Effects of circadian mutations and LD periodicity on the life span of Drosophila melanogaster. J. Biol. Rhythms 13, 471-478.
83. Kido, A., & Ito, K. (2002). Mushroom bodies are not required for courtship behavior by normal and sexually mosaic Drosophila. J. Neurobiol. 52, 302-311.
84. Kitamoto, T. (2002). Conditional disruption of synaptic transmission induces male-male courtship behavior in Drosophila. Proc. Nat. Acad. Sci. USA 99, 13232-13237.
85. Konopka, R.J., & Benzer, S. (1971). Clock mutants of Drosophila melanogaster. Proc. Nat. Acad. Sci. USA 68, 2112-2116.
86. Konopka, R.J., Kyriacou, C.P., & Hall, J.C. (1996). Mosaic analysis in the Drosophila CNS of circadian and courtship-song rhythms affected by a period clock mutation. J. Neurogenet. 11, 117-140.
87. Kulkurni, S.J., & Hall, J.C. (1987). Behavioral and cytogenetic analysis of the cacophony courtship song mutant and interacting genetic variants in Drosophila melanogaster. Genetics 115, 461-475.
88. Kulkarni, S.J., Steinlauf, A.F., & Hall, J.C. (1988). The dissonance mutant of courtship song in Drosophila melanogaster: Isolation, behavior and cytogenetics. Genetics 118, 267-285.
89. Kuniyoshi, H., Motoyama, J., Baba, K., Ueda, R., Kondo, S., Awano, W., & Yamamoto, D. (2002). lingerer, a Drosophila gene involved in initiation and termination of copulation, encodes a novel set of proteins expressed in the central nervous system. Submitted.
90. Kyriacou, C.P., Greenacre, M.L., Thackeray, J.R., & Hall, J.C. (1993). Genetic and molecular analysis of song rhythms in Drosophila. In M.W. Young (Ed.), Molecular Genetics of Biological Rhythms (pp. 171-193). New York: Marcel Dekker.
91. Kyriacou, C.P., & Hall, J.C. (1980). Circulation rhythm mutations in Drosophila melanogaster affect short-term fluctuations in the male's courtship song. Proc. Nat. Acad. Sci. USA 77, 6929-6933.
92. Kyriacou, C.P., & Hall, J.C. (1982). The function of courtship song rhythms in Drosophila. Anim. Behav. 30, 794-801.
93. Kyriacou, C.P., & Hall, J.C. (1984). Learning and memory mutations impair acoustic priming of mating behaviour in Drosophila. Nature 308, 62-65.
94. Kyriacou, C.P., & Hall, J.C. (1986). Interspecific genetic control of courtship song production and reception in Drosophila. Science 232, 494-497.
95. Kyriacou, C.P., Oldroyd, M., Wood, J., Sharp, M., & Hill, M. (1990). Clock mutations alter developmental timing in Drosophila. Heredity 64, 395-401.
96. Labeur, C., Dallerac, R., & Wicker-Thomas, C. (2002). Involvement of desat1 gene in the control of Drosophila melanogaster pheromone biosynthesis. Genetica 114, 269-274.
97. Lawrence, P.A., & Johnston, P. (1986). The muscle pattern of a segment of Drosophila may be determined by neurons and not by contributing myoblasts. Cell 45, 505-513.
98. Lee, G., Foss, M., Goodwin, Carlo, T., Taylor, B.J., & Hall, J.C. (2000). Spatial, temporal, and sexually dimorphic expression patterns of the fruitless gene in the Drosophila CNS. J. Neurobiol. 43, 404-426.
99. Lee, G., & Hall, J.C. (2001). Abnormalities of male-specific FRU protein and serotonin expression in the central nervous system of fruitless mutants in Drosophila. J. Neurosci. 21, 513-526.
100. Lee, G., Villella, A., Taylor, B.J., & Hall, J.C. (2001). New reproductive anomalies in fruitless-mutant Drosophila males: Extreme lengthening of mating durations and infertility correlated with defective serotonergic innervation of reproductive organs. J. Neurobiol. 47, 121-149.
101. Lloyd, V.K., Sinclair, D.A., Alperyn, M., & Grigliatti, T.A. (2002). Enhancer of garnet/deltaAP-3 is a cryptic allele of the white gene and identifies the intracellular transport system for the white protein. Genome 45, 296-312.
102. Lung, O., Tram, U., Finnerty, C.M., Eipper-Mains, M.A., Kalb, J.M., & Wolfner, M.F. (2002). The Drosophila melanogaster seminal fluid protein Acp62F is a protease inhibitor that is toxic upon ectopic expression. Genetics 160, 211-224.
103. Manning, A. (1965). Drosophila and the evolution of behavior. Viewpoints Biol. 4, 125-169.
104. McBride, S.M., Giuliani, G., Choi, C., Krause, P., Correale, D., Watson, K, Baker, G., & Siwicki, K.K. (1999). Mushroom body ablation impairs short-term memory and long-term memory of courtship conditioning in Drosophila melanogaster. Neuron 24, 967-977.
105. McMahon, C., Sureau, G., & Ferveur, J.-F. (2002). Mapping of genetic loci that change pheromone discrimination in Drosophila males. Genet. Res. 79, 149-159.
106. Moore, M.S., DeZazzo, J., Luk, A.Y., Tully, T., Singh, C.M., & Heberlein, U. (1998). Ethanol intoxication in Drosophila: Genetic and pharmacological evidence for regulation by the cAMP signaling pathway. Cell 93, 997-1007.
107. Nakano, Y., Fujitani, K., Kurihara, J., Ragan, J., Usui-Aoki, K., Shimoda, L., Lukacsovich, T., Suzuki, K., Sezaki, M., Sano, Y., Ueda, R., Awano, W., Kaneda, M., Umeda, M., & Yamamoto, D. (2001). Mutations in the novel membrane protein spinster interfere with programmed cell death and cause neural degeneration in Drosophila melanogaster. Molec. Cell. Biol. 21, 3775-3788.
108. Neubaum, D.M., & Wolfner, M.F. (1999). Wise, winsome, or weird? Mechanisms of sperm storage in female animals. Curr. Top. Devel. Biol. 41, 67-97.
109. O'Dell, K.M.C., Armstrong, J.D., Yang, M.Y., & Kaiser, K. (1995). Functional dissection of the Drosophila mushroom bodies by selective feminization of genetically defined subcompartments. Neuron 15, 55-61.
110. Orgad, S., Rosenfeld, G., Greenspan, R.J., & Segal, D. (2000). courtless, the Drosophila UBC7 homolog, is involved in male courtship behavior and spermatogenesis. Genetics 155, 1267-1280.
111. Radovic, A., Wittkopp, P.J., Long, A.D., & Drapeau, M.D. (2002). Immunohistochemical colocalization of Yellow and male-specific Fruitless in Drosophila melanogaster neuroblasts. Biochem Biophys. Res. Commun. 293, 1262-1264.
112. Reif, M., Linsenmaier, K.E., & Heisenberg, M. (2002). Evolutionary significance of courtship conditioning in Drosophila melanogaster. Anim. Behav. 63, 143-155.
113. Reiner C., & Brooks, M. (1973). 2000 and Thirteen. Burbank, CA: Warner Bros. Records, Inc.
114. Rendahl, K.G., Gaukhshteyn, N., Wheeler, D.A., Fry, T.A., & Hall, J.C. (1996). Defects in courtship and vision caused by amino-acid substitutions in a putative RNA-binding protein encoded by the nonA gene of Drosophila. J. Neurosci. 16, 1511-1522.
115. Rendahl, K.G., Jones, K.R., Kulkarni, S.J., Bagully, S.H., & Hall, J.C. (1992). The dissonance mutation at the no-on-transient-A locus of D. melanogaster: Genetic control of courtship song and visual behaviors by a protein with putative RNA-binding motifs. J. Neurosci. 12, 390-407.
116. Ritchie, M.G., Halsey, E.J., & Gleason, J.M. (1999). Drosophila song as a species-specific mating signal and the behavioural importance of Kyriacou & Hall cycles in D. melanogaster song. Anim. Behav. 58, 649-657.
117. Roman, G., & Davis, R.L. (2001). Molecular biology and anatomy of Drosophila olfactory associative learning. BioEssays 23, 571-581.
118. Rybak, F., Sureau, G., & Aubin, T. (2002). Functional coupling of acoustic and chemical signals in the courtship behavior of the male Drosophila melanogaster. Proc. Roy. Soc. Lond. B 269, 695-701.
119. Ryner, L.C., Goodwin, S.F., D.H. Castrillon, D.H., Anand, A., Villella, A., Baker, B.S., Hall, J.C., Taylor, B.J., & Wasserman, S.A. (1996). Control of male sexual behavior and sexual orientation in Drosophila by the fruitless gene. Cell 87, 1079-1089.
120. Sakai, T., & Ishida, N. (2001a). Circadian rhythms of female mating activity governed by clock genes in Drosophila. Proc. Nat. Acad. Sci. USA 98, 9221-9225.
121. Sakai, T, & Ishida, N. (2001b). Time, love and species. Neuroendocrinol. Lett. 22, 222-228.
122. Saudan, P., Hauck, K., Soller, M., Choffat, Y., Ottiger, M., Sporri, M., Ding, Z., Hess, D., Gehrig, P.M., Klauser, S., Hunziker, P., & Kubli, E. (2002). Ductus ejaculatorius peptide 99B (DUP99B), a novel Drosophila melanogaster sex-peptide pheromone. Eur. J. Biochem. 269, 989-997.
123. Schilcher, F.V. (1976a). The role of auditory stimuli in the courtship of Drosophila melanogaster. Anim. Behav. 24, 18-26.
124. Schilcher, F.V. (1976b). The function of pulse song and sine song in the courtship of Drosophila melanogaster. Anim. Behav. 24, 622-625.
125. Schilcher, F.V. (1977). A mutation which changes courtship song in Drosophila melanogaster. Behav. Genet. 7, 251-259.
126. Schilcher, F.V., & Hall, J.C. (1979). Neural topography of courtship song in sex mosaics of Drosophila melanogaster. J. Comp. Physiol. A 129, 85-95.
127. Shaw, P.J., Tononi, G., Greenspan, R.J., & Robinson, D.F. (2002). Stress response genes protect against lethal effects of sleep deprivation in Drosophila. Nature 417, 287-291.
128. Siegel, R.W., & Hall, J.C. (1979). Conditioned responses in courtship behavior of normal and mutant Drosophila. Proc. Nat. Acad. Sci. USA 76, 3430-3434.
129. Smith, L.A., Peixoto, A.A., Kramer, E.W., Villella, A., & Hall, J.C. (1998). Courtship and visual defects of cacophony mutants reveal functional complexity of a calcium-channel α1 subunit in Drosophila. Genetics 149, 1407-1426.
130. Smith, L.A., Wang, X., Peixoto, A.A., Neumann, E.K., Hall, L.M., & Hall, J.C. (1996). A Drosophila calcium-channel α1 subunit gene maps to a genetic locus associated with behavioral and neural defects. J. Neurosci. 16, 7868-7879.
131. Stanewsky, R., Fry, T.A., Reim, I., Saumweber, H., & Hall, J.C. (1996). Bioassaying putative RNA-binding motifs in a protein encoded by a gene that influences courtship and visually mediated behavior in Drosophila: In vitro mutagenesis of nonA. Genetics 143, 259-275.
132. Sturtevant, A.H. (1915). Experiments on sex recognition and the problem of sex selection in Drosophila. J. Anim. Behav. 5, 351-366.
133. Sturtevant, A.H. (1965). A History of Genetics. New York: Harper & Row.
134. Swinderin, B.V., & Hall, J.C. (1995). Analysis of conditioned courtship in dusky-Andante rhythm mutants of Drosophila. Learn. Mem. 2, 49-61.
135. Tauber, E., & Eberl, D.F. (2001). Song production in auditory mutants of Drosophila: The role of sensory feedback. J. Comp. Physiol. A 187, 341-348.
136. Taylor, B.J. (1992). Differentiation of a male-specific muscle in Drosophila melanogaster does not require the sex-determining genes doublesex or intersex. Genetics 132, 179-191.
137. Tompkins, L. (1984). Genetic analysis of sex appeal in Drosophila melanogaster. Behav. Genet. 14, 453-482.
138. Tompkins, L., Hall, J.C., & Hall, L.M. (1980). Courtship-stimulating volatile compounds from normal and mutant Drosophila. J. Insect Physiol. 26, 689-697.
139. Tram, U., & Wolfner, M.F. (1998). Seminal fluid regulation of female sexual attractiveness in Drosophila melanogaster. Proc. Nat. Acad. Sci. USA 95, 4051-4054.
140. Tsien, J.Z., Chen, D.F., Gerber, D., Tom, C., Mercer, E.H., Anderson, D.J., Mayford, M., Kandel, E.R. & Tonegawa, S. (1996a). Subregion- and cell type-restricted gene knockout in mouse brain. Cell 87, 1317-1326.
141. Tsien, J.Z, Huerta, P.T., & Tonegawa, S. (1996b). The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory. Cell 87, 1327-1338.
142. Usui-Aoki, K., Ito, H., Ui-Yei, K., Takahashi, J., Lucacsovitch, T., Awano, W., Nakata, H., Piao, X.F., Nillson, E.E., Tomida, J.-J., & Yamamoto, D. (2000). Formation of the male-specific muscle in female Drosophila by ectopic fruitless expression. Nat. Cell Biol. 2, 500-506.
143. Vaias, L.J., Napolitano, L.M., & Tompkins, L. (1993). Identification of stimuli that mediate experience-dependent modification of homosexual courtship in Drosophila melanogaster. Behav. Genet. 23, 91-97.
144. Villella, A., Gailey, D.A., Berwald, B., Ohshima, S., Barnes, P.T., & Hall, J.C. (1997). Extended reproductive roles of the fruitless gene in Drosophila melanogaster revealed by behavioral analysis of new fru mutants. Genetics 147, 1107-1130.
145. Villella, A., & Hall, J.C. (1996). Courtship anomalies caused by doublesex mutations in Drosophila melanogaster. Genetics 143, 331-344.
146. Waddell, S., & Quinn, W.G. (2001). Flies, genes, and learning. Ann. Rev Neurosci. 24, 1283-1309.
147. Ward, S. (1977), Invertebrate neurogenetics. Ann. Rev. Genetics 11, 415-450.
148. Waterbury, J.A., Jackson, L.L., & Schedl, P. (1999). Analysis of the Doublesex female protein in Drosophila melanogaster: Role in sexual differentiation and behavior dependent on Intersex. Genetics 152, 1653-1667.
149. Weiner, J. (1999). Time, Love, Memory. New York: Alfred A. Knopf.
150. Wheeler, D.A., Kyriacou, C.P., Greenacre, M.L., Yu, Q., Rutila, J.E., Rosbash, M., & Hall, J.C. (1991). Molecular transfer of a species-specific behavior from Drosophila simulans to Drosophila melanogaster. Science 251, 1082-1085.
151. Wicker-Thomas, C., & Jallon, J.-M. (2001). Control of female pheromones in Drosophila melanogaster by homeotic genes. Genet Res. 78, 235-242.
152. Williams, J.A., & Sehgal, A. (2001). Molecular components of the circadian system in Drosophila. Ann. Rev. Physiol. 63, 729-755.
153. Wills, C. (1993). The Runaway Brain. New York: Basic Books.
154. Winchester, G. (1996). The Morgan pedigree. Curr. Biol. 6, 100-101.
155. Wolfner, M.F. (1997). Tokens of love: Functions and regulation of Drosophila male accessory gland products. Insect Biochem. Molec. Biol. 27, 179-192.
156. Xu, A., Park, S.K., D'Mello, S., Kim, E., Wang, Q., & Pikielny, C.W. (2002). Novel genes expressed in subsets of chemosensory sensilla on the front legs of male Drosophila melanogaster. Cell Tiss. Res. 307, 381-392.
157. Xue, L., & Noll, M. (2000). Drosophila female sexual behavior induced by sterile males showing copulation complementation. Proc. Nat. Acad. Sci. USA 97, 3272-3275.
158. Yamamoto, D. (2001). The Drosophila fruitless gene: Neural sex and male sexual orientation. Seikagaku 73, 1141-1144.
159. Yamamoto, D., Fujitani, K., Usui, K., Ito, H., & Nakano, Y. (1998). From behavior to development: Genes for sexual behavior define the neuronal sexual switch in Drosophila. Mech. Devel. 73, 135-146.
160. Yamamoto, D., Jallon, J.-M., & Komatsu, A. (1997). Genetic dissection of sexual behavior in Drosophila melanogaster. Ann. Rev. Entomol. 42, 551-585.
161. Yamamoto, D., & Nakano, Y. (1999). Sexual behavior mutants revisited: Molecular and cellular basis of Drosophila mating. Cell. Molec. Life Sci. 56, 634-646.
162. Young, M.W., & Kay, S.A. (2001). Time zones: A comparative genetics of circadian clocks. Nat. Rev. Genet. 2, 702-715.
163. Zawistowski, S., & Richmond, R.C. (1985). Experience-mediated courtship reduction and competition for mates by male Drosophila melanogaster. Behav Genet. 15, 561-569.
164. Zhang, S.-D., & Odenwald, W.F. (1995). Misexpression of the white gene triggers male-male courtship in Drosophila. Proc. Nat. Acad. Sci. USA 92, 5525-5529.