New reproductive anomalies in fruitless-mutant Drosophila males: Extreme lengthening of mating durations and infertility correlated with defective serotonergic innervation of reproductive organs

Journal of Neurobiology

Volumn 47, Issue 2, 2001, Pages 121-149

  Lee, Gyunghee ^a,c   Villella, Adriana ^a   Taylor, Barbara J ^b   Hall, Jeffrey C ^a  

^a BRANDEIS UNIVERSITY   (United States)

^b OREGON STATE UNIVERSITY   (United States)

^c UNIVERSITY OF TENNESSEE   (United States)

Author keywords

5HT; Copulation; Drosophila melanogaster; fru mutant combinations; Infertility; Male internal sex organs; Serotonergic processes of abdominal neurons

Indexed keywords

SEROTONIN;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; COPULATION; COURTSHIP; DROSOPHILA MELANOGASTER; FEMALE; GENE CONTROL; GENE MUTATION; MALE; MALE GENITAL SYSTEM; MALE INFERTILITY; MATING; NONHUMAN; PRIORITY JOURNAL; SEROTONINERGIC NERVE CELL; SEXUAL BEHAVIOR; SPERMATOZOON MIGRATION;

ANIMALS; COPULATION; COURTSHIP; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; FEMALE; FERTILITY; HETEROZYGOTE; HUMANS; INFERTILITY, MALE; MALE; NERVE TISSUE PROTEINS; SEROTONIN; SPERM COUNT; STOCHASTIC PROCESSES; TESTIS; TRANSCRIPTION FACTORS;

EID: 0035071147     PISSN: 00223034     EISSN: None     Source Type: Journal    
DOI: 10.1002/neu.1021     Document Type: Article

References (92)

1. Control of copulation duration in Drosophila
2. The sex determination gene fruitless, in addition to controlling male sexual behaviors in Drosophila, has sex-nonspecific vital functions
3. The Drosophila Bruton's tyrosine kinase (Btk) homolog is required for adult survival and male genital formation
4. Structure and ultrastructure of the male reproductive system in Drosophila melanogaster Meig. 2. The genital duct and accessory glands
5. 5-hydroxytryptamine2C receptors on spinal neurons controlling penile erection in the rat
6. A polycystic kidney-disease gene homologue required for male mating behaviour in C. elegans
7. Localization of the Drosophila accessory gland protein Acp36DE in the mated female suggests a role in sperm storage
8. Toward a molecular genetic analysis of spermatogenesis in Drosophila melanogaster: Characterization of malesterile mutants generated by single P element mutagenesis
9. Determination of male-specific gene expression in Drosophila accessory glands
10. The accessory gland proteins in male Drosophila: Structural, reproductive and evolutionary aspects
11. Innervation is essential for the development and differentiation of a sex-specific adult muscle in Drosophila melanogaster
12. Genomic organisation and characterization of the neural sex-determination gene fruitless (fru) in the Hawaiian species Drosophila heteroneura
13. Structure, cell-specific expression, and mating-induced regulation of a Drosophila melanogaster accessory gland gene
14. External morphology of the adult
15. The pheromonal role of cuticular hydrocarbons in communication in Drosophila melanogaster
16. Courtship behavior of brain mosaics in Drosophila
17. Dissatisfaction, a gene involved in sex-specific behavior and neural development
18. Some aspects of the reproductive biology of Drosophila: Sperm transfer, sperm storage, and sperm utilization
19. Behavior and cytogenetics of fruitless in Drosophila melanogaster: Different courtship defects caused by separate, closely linked lesions
20. The Muscle of Lawrence in Drosophila: A case of repeated evolutionary loss
21. Elements of the fruitless locus regulate development of the muscle of Lawrence, a male-specific structure in the abdomen of Drosophila melanogaster adults
22. Interactions between su(Hw)-binding regions in neighboring y2 and scD1 alleles hinder trans-activation of the y2 promoter by yellow enhancers located on a homologous chromosome
23. Ejaculate esterase 6 and initial sperm use by female Drosophila melanogaster
24. Male sexual circuitry (Working Group for the Study of Central Mechanisms in Erectile Dysfunction)
25. Molecular neurogenetics of sexual differentiation and behaviour
26. Aberrant splicing and altered spatial expression patterns in fruitless mutants of Drosophila melanogaster
27. Künstliche befruchtung bei Drosophila
28. Understanding the genetic construction of behavior
29. Flies, genes, learning and memory
30. Courtship in Drosophila
31. Sperm transfer and use in the multiple mating system of Drosophila
32. Courtship among males due to a male-sterile mutation in Drosophila melanogaster
33. Control of male reproductive behavior by the central nervous system of Drosophila: Dissection of a courtship pathway by genetic mosaics
34. The mating of a fly
35. Neurogenetics of courtship in Drosophila
36. The Drosophila seminal fluid protein Acp26Aa stimulates release of oocytes by the ovary
37. Regulation of sex-specific selection of fruitless 5′ splice sites by transformer and transformer-2
38. Mating and hormonal triggers regulate accessory gland gene expression in male Drosophila
39. A Drosophila seminal fluid protein, Acp26Aa, stimulates egg laying in females for 1 day after mating
40. Effects of the male accessory gland secretion on oviposition and remating in females of Drosophila melanogaster
41. Proteins of the Drosophila melanogaster male reproductive system: Two-dimensional gel patterns of proteins synthesized in the XO, XY, and XYY testis and paragonial gland and evidence that the Y chromosome does not code for structural sperm proteins
42. Sexual orientation in Drosophila is altered by the satori mutation in the sex-determination gene fruitless that encodes a zinc finger protein with a BTB domain
43. Probing the function of Drosophila melanogaster accessory glands by directed cell ablation
44. Origin and neurochemical characteristics of nerve fibers supplying the mammalian vas deferens
45. The number of sperm present in reproductive tracts of D. melanogaster females
46. The Drosophila sex-peptide: A peptide pheromone involved in reproduction
47. The genetic specification of pattern in a Drosophila muscle
48. The muscle pattern of a segment of Drosophila may be determined by neurons and not by contributing myoblasts
49. Spatial, temporal, and sexually dimorphic expression patterns of the fruitless gene in the Drosophila CNS
50. A newly uncovered phenotype associated with the fruitless gene of Drosophila melanogaster: Aggression-like head interactions between mutant males
51. Abnormalities of male-specific FRU protein and serotonin expression in the central nervous system of fruitless mutants in Drosophila
52. Sperm transfer, storage, displacement and utilization in Drosophila melanogaster
53. Expression of synaptotagmin in Drosophila reveals transport and localization of synaptic vesicles to the synapse
54. Sensory regulation of male mating behavior in Caenorhabditis elegans
55. Serotonin-deficient mutants and male mating behavior in the nematode Caenorhabditis elegans
56. The control of sexual receptivity in female Drosophila
57. Stimulation of spinal serotonergic receptors facilitates seminal emission and suppresses penile erectile reflexes
58. Central control of penile erection
59. The physiology of male sexual behavior
60. The internal anatomy and histology of the imago of Drosophila melanogaster
61. Synthesis of two Drosophila male accessory gland proteins and their fate after transfer to the female during mating
62. Structure and expression of a Drosophila male accessory gland gene whose product resembles a peptide pheromone precursor
63. An analysis of transvection at the yellow locus of Drosophila melanogaster
64. Core promoter elements regulate transcription on a separate chromosome in trans
65. 1 receptors
66. Regulation of male sexual function
67. Mated Drosophila melanogaster females require a seminal fluid protein, Acp36DE, to store sperm efficiently
68. Wise, winsome, or weird? Mechanisms of sperm storage in female animals
69. Fruitless is in the regulatory pathway by which ectopic mini-white and transformer induce bisexual courtship in Drosophila
70. Binding sites of Drosophila melanogaster sex peptide pheromones
71. Ejaculatory duct obstruction in infertile men
72. Male and female cooperate in the prohormone-like processing of a Drosophila melanogaster seminal fluid protein
73. The insemination reaction and its bearing on the problem of speciation in the mulleri subgroup
74. Neurobiology of sexual behavior
75. Control of male sexual behavior and sexual orientation in Drosophila by the fruitless gene
76. The induction of ribosome biosynthesis in a nonmitotic secretory tissue
77. Sexual mimicry regulates the attractiveness of mated Drosophila melanogaster females
78. Mechanism of ejection during ejaculation: Identification of a urethrocavernosus reflex
79. Mating behavior within the genus Drosophila (Diptera)
80. Oxytocinergic and serotonergic innervation of identified lumbosacral nuclei controlling penile erection in the male rat
81. Sex-specific differentiation of a male-specific abdominal muscle, the Muscle of Lawrence, is abnormal in hydroxyurea-treated and in fruitless male flies
82. The different effects on courtship of volatile compounds from mated and virgin Drosophila females
83. Seminal fluid regulation of female sexual attractiveness in Drosophila melanogaster
84. Male seminal fluid proteins are essential for sperm storage in Drosophila melanogaster
85. Formation of the male-specific muscle in female Drosophila by ectopic fruitless expression
86. Extended reproductive roles of the fruitless gene in Drosophila melanogaster revealed by behavioral analysis of new fru mutants
87. Tokens of love: Functions and regulation of Drosophila male accessory gland products
88. Drosophila female sexual behavior induced by sterile males showing copulation complementation
89. Genetic dissection of sexual behavior in Drosophila melanogaster
90. Sexual behavior mutants revisited: Molecular and cellular basis of Drosophila mating