메뉴 건너뛰기




Volumn 56, Issue 3, 2002, Pages 511-525

Role of insulin in Alzheimer's disease: Approaches emerging from basic animal research and neurocognitive studies in humans

Author keywords

Amyloid; Event related brain potentials; Frontal negative slow wave; Insulin degrading enzyme; Intranasal drug delivery; Memory; Selective attention; Tau protein

Indexed keywords

AMYLOID BETA PROTEIN; INSULIN; INSULINASE; TAU PROTEIN;

EID: 0036660007     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/ddr.10101     Document Type: Review
Times cited : (9)

References (157)
  • 1
    • 0026740795 scopus 로고
    • Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease
    • Arriagada PV, Growdon JH, Hedley-Whyte ET, Hyman BT. 1992. Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease. Neurology 42:631-639.
    • (1992) Neurology , vol.42 , pp. 631-639
    • Arriagada, P.V.1    Growdon, J.H.2    Hedley-Whyte, E.T.3    Hyman, B.T.4
  • 2
    • 0023930592 scopus 로고
    • Comparison of nasal, rectal, buccal, sublingual and intramuscular insulin efficacy and the effects of a bile salt absorption promoter
    • Aungst BJ, Rogers NJ, Shefter E. 1988. Comparison of nasal, rectal, buccal, sublingual and intramuscular insulin efficacy and the effects of a bile salt absorption promoter. J Pharmacol Exp Ther 244:23-27.
    • (1988) J Pharmacol Exp Ther , vol.244 , pp. 23-27
    • Aungst, B.J.1    Rogers, N.J.2    Shefter, E.3
  • 3
    • 0022477568 scopus 로고
    • Transneuronal transport of peroxidase-conjugated wheat germ agglutinin (WGA-HRP) from the olfactory epithelium to the brain of the adult rat
    • Baker H, Spencer RF. 1986. Transneuronal transport of peroxidase-conjugated wheat germ agglutinin (WGA-HRP) from the olfactory epithelium to the brain of the adult rat. Exp Brain Res 63:461-473.
    • (1986) Exp Brain Res , vol.63 , pp. 461-473
    • Baker, H.1    Spencer, R.F.2
  • 4
    • 0022552302 scopus 로고
    • Avenues for entry of peripherally administered protein to the central nervous system in mouse, rat, and squirrel monkey
    • Balin BJ, Broadwell RD, Salcman M, El-Kalliny M. 1986. Avenues for entry of peripherally administered protein to the central nervous system in mouse, rat, and squirrel monkey. J Comp Neurol 251:260-280.
    • (1986) J Comp Neurol , vol.251 , pp. 260-280
    • Balin, B.J.1    Broadwell, R.D.2    Salcman, M.3    El-Kalliny, M.4
  • 5
    • 0031456345 scopus 로고    scopus 로고
    • Selective, physiological transport of insulin across the blood-brain barrier: Novel demonstration by species-specific radioimmunoassays
    • Banks WA, Jaspan JB, Kastin AJ. 1997. Selective, physiological transport of insulin across the blood-brain barrier: novel demonstration by species-specific radioimmunoassays. Peptides 18:1257-1262.
    • (1997) Peptides , vol.18 , pp. 1257-1262
    • Banks, W.A.1    Jaspan, J.B.2    Kastin, A.J.3
  • 6
    • 0027202354 scopus 로고
    • The olfactory nerve and not the trigeminal nerve is the major site of CNS entry for mouse hepatitis virus, strain JHM
    • Barnett EM, Perlman S. 1993. The olfactory nerve and not the trigeminal nerve is the major site of CNS entry for mouse hepatitis virus, strain JHM. Virology 194:185-191.
    • (1993) Virology , vol.194 , pp. 185-191
    • Barnett, E.M.1    Perlman, S.2
  • 7
    • 0023729911 scopus 로고
    • Olfactory neural pathway in mouse hepatitis virus nasoencephalitis
    • Barthold SW. 1988. Olfactory neural pathway in mouse hepatitis virus nasoencephalitis. Acta neuropath 76:502-506.
    • (1988) Acta Neuropath , vol.76 , pp. 502-506
    • Barthold, S.W.1
  • 10
    • 0027373646 scopus 로고
    • Immunocytochemical detection of insulin receptor substrate-1 (IRS-1) in rat brain: Colocalization with phosphotyrosine
    • Baskin DG, Sipols AJ, Schwartz MW, White MF. 1993. Immunocytochemical detection of insulin receptor substrate-1 (IRS-1) in rat brain: colocalization with phosphotyrosine. Regul Pept 48:257-266.
    • (1993) Regul Pept , vol.48 , pp. 257-266
    • Baskin, D.G.1    Sipols, A.J.2    Schwartz, M.W.3    White, M.F.4
  • 13
    • 0030069591 scopus 로고    scopus 로고
    • Insulin transport from plasma into the central nervous system is inhibited by dexamethasone in dogs
    • Baura GD, Foster DM, Kaiyala K, Porte D Jr, Kahn SE, Schwartz MW. 1996. Insulin transport from plasma into the central nervous system is inhibited by dexamethasone in dogs. Diabetes 45:86-90.
    • (1996) Diabetes , vol.45 , pp. 86-90
    • Baura, G.D.1    Foster, D.M.2    Kaiyala, K.3    Porte D., Jr.4    Kahn, S.E.5    Schwartz, M.W.6
  • 14
    • 0026357855 scopus 로고
    • Effect of intracerebroventricularly administered insulin on brain monoamines and acetylcholine in euglycaemic and alloxan-induced hyperglycaemic rats
    • Bhattacharya SK, Saraswati M. 1991. Effect of intracerebroventricularly administered insulin on brain monoamines and acetylcholine in euglycaemic and alloxan-induced hyperglycaemic rats. Indian J Exp Biol 29:1095-1100.
    • (1991) Indian J Exp Biol , vol.29 , pp. 1095-1100
    • Bhattacharya, S.K.1    Saraswati, M.2
  • 16
    • 0032572613 scopus 로고    scopus 로고
    • Water maze learning and hippocampal synaptic plasticity in streptozotocin-diabetic rats: Effects of insulin treatment
    • Biessels GJ, Kamal A, Urban IJ, Spruijt BM, Erkelens DW, Gispen WH. 1998. Water maze learning and hippocampal synaptic plasticity in streptozotocin-diabetic rats: effects of insulin treatment. Brain Res 800:125-135.
    • (1998) Brain Res , vol.800 , pp. 125-135
    • Biessels, G.J.1    Kamal, A.2    Urban, I.J.3    Spruijt, B.M.4    Erkelens, D.W.5    Gispen, W.H.6
  • 18
    • 0023119289 scopus 로고
    • Influences of ACTH 4-10 on event-related potentials reflecting attention in man
    • Born J, Fehm-Wolfsdorf G, Voigt KH, Fehm HL. 1987. Influences of ACTH 4-10 on event-related potentials reflecting attention in man. Physiol Behav 39:83-87.
    • (1987) Physiol Behav , vol.39 , pp. 83-87
    • Born, J.1    Fehm-Wolfsdorf, G.2    Voigt, K.H.3    Fehm, H.L.4
  • 20
    • 0022371436 scopus 로고
    • Insulin receptors and insulin modulation of norepinephrine uptake in neuronal cultures from rat brian
    • Boyd FT, Clarke DW, Muther TF, Raizada MK. 1985. Insulin receptors and insulin modulation of norepinephrine uptake in neuronal cultures from rat brian. J Biol Chem 260:15880-15884.
    • (1985) J Biol Chem , vol.260 , pp. 15880-15884
    • Boyd, F.T.1    Clarke, D.W.2    Muther, T.F.3    Raizada, M.K.4
  • 22
    • 0027308924 scopus 로고
    • Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding
    • Bramblett GT, Goedert M, Jakes R, Merrick SE, Trojanowski JQ, Lee VM. 1993. Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding. Neuron 10:1089-1099.
    • (1993) Neuron , vol.10 , pp. 1089-1099
    • Bramblett, G.T.1    Goedert, M.2    Jakes, R.3    Merrick, S.E.4    Trojanowski, J.Q.5    Lee, V.M.6
  • 25
    • 0023205478 scopus 로고
    • Pathogenesis of Borna disease in rats: Evidence that intraaxonal spread is the major route for virus dissemination and the determinant for disease incubation
    • Carbone KM, Duchala CS, Griffin JW, Kincaid AL, Narayan O. 1987. Pathogenesis of Borna disease in rats: evidence that intraaxonal spread is the major route for virus dissemination and the determinant for disease incubation. J Virol 61:3431-3440.
    • (1987) J Virol , vol.61 , pp. 3431-3440
    • Carbone, K.M.1    Duchala, C.S.2    Griffin, J.W.3    Kincaid, A.L.4    Narayan, O.5
  • 26
    • 0027157422 scopus 로고
    • The demonstration of long latency potentials in the CA1 region of the rat hippocampal slice
    • Caudle RM. 1993. The demonstration of long latency potentials in the CA1 region of the rat hippocampal slice. Brain Res 613:247-250.
    • (1993) Brain Res , vol.613 , pp. 247-250
    • Caudle, R.M.1
  • 27
    • 0030815546 scopus 로고    scopus 로고
    • Impaired modulation of AMPA receptors by calcium-dependent processes in streptozotocin-induced diabetic rats
    • Chabot C, Massicotte G, Milot M, Trudeau F, Gagne J. 1997. Impaired modulation of AMPA receptors by calcium-dependent processes in streptozotocin-induced diabetic rats. Brain Res 768:249-256.
    • (1997) Brain Res , vol.768 , pp. 249-256
    • Chabot, C.1    Massicotte, G.2    Milot, M.3    Trudeau, F.4    Gagne, J.5
  • 29
    • 0033058656 scopus 로고    scopus 로고
    • Insulin causes a transient tyrosine phosphorylation of NR2A and NR2B NMDA receptor subunits in rat hippocampus
    • Christie JM, Wenthold RJ, Monaghan DT. 1999. Insulin causes a transient tyrosine phosphorylation of NR2A and NR2B NMDA receptor subunits in rat hippocampus. J Neurochem 72:1523-1528.
    • (1999) J Neurochem , vol.72 , pp. 1523-1528
    • Christie, J.M.1    Wenthold, R.J.2    Monaghan, D.T.3
  • 31
    • 0026597107 scopus 로고
    • Glucose and memory in mild senile dementia of the Alzheimer type
    • Craft S, Zallen G, Baker L. 1992. Glucose and memory in mild senile dementia of the Alzheimer type. J Clin Exp Neuropsychol 14:253.
    • (1992) J Clin Exp Neuropsychol , vol.14 , pp. 253
    • Craft, S.1    Zallen, G.2    Baker, L.3
  • 37
    • 0013816089 scopus 로고
    • Facilitated transfer of glucose from blood into brain tissue
    • Crone C. 1965. Facilitated transfer of glucose from blood into brain tissue. J Physiol (Lond) 181:103-113.
    • (1965) J Physiol (Lond) , vol.181 , pp. 103-113
    • Crone, C.1
  • 38
    • 0019614430 scopus 로고
    • Surprise...surprise?
    • Donchin E. 1981. Surprise...surprise? Psychophysiology 18:493.
    • (1981) Psychophysiology , vol.18 , pp. 493
    • Donchin, E.1
  • 39
    • 0029018829 scopus 로고
    • Fourday hyperinsulinemia in euglycemic conditions alters local cerebral glucose utilisation in specific brain nuclei of freely moving rats
    • Doyle P, Cusin I, Rohner-Jeanrenaud F, Jeanrenaud B. 1995. Fourday hyperinsulinemia in euglycemic conditions alters local cerebral glucose utilisation in specific brain nuclei of freely moving rats. Brain Res 684:47-55.
    • (1995) Brain Res , vol.684 , pp. 47-55
    • Doyle, P.1    Cusin, I.2    Rohner-Jeanrenaud, F.3    Jeanrenaud, B.4
  • 40
    • 0028598190 scopus 로고
    • Intracerebro-ventricular injection of streptozotocin induces discrete local changes in cerebral glucose utilization in rats
    • Duelli R, Schrock H, Kuschinsky W, Hoyer S. 1994. Intracerebro-ventricular injection of streptozotocin induces discrete local changes in cerebral glucose utilization in rats. Int J Dev Neurosci 12:737-743.
    • (1994) Int J Dev Neurosci , vol.12 , pp. 737-743
    • Duelli, R.1    Schrock, H.2    Kuschinsky, W.3    Hoyer, S.4
  • 41
    • 0023636719 scopus 로고
    • Blood-brain barrier transcytosis of insulin in developing rabbits
    • Duffy KR, Pardridge WM. 1987. Blood-brain barrier transcytosis of insulin in developing rabbits. Brain Res 420:32-38.
    • (1987) Brain Res , vol.420 , pp. 32-38
    • Duffy, K.R.1    Pardridge, W.M.2
  • 42
    • 0026785763 scopus 로고
    • Raised glucose levels enhance scopolamine-induced acetylcholine overflow from the hippocampus: An in vivo microdialysis study in the rat
    • Durkin TP, Messier C, De Boer P, Westerink BHC. 1992. Raised glucose levels enhance scopolamine-induced acetylcholine overflow from the hippocampus: an in vivo microdialysis study in the rat. Behav Brain Res 49:181.
    • (1992) Behav Brain Res , vol.49 , pp. 181
    • Durkin, T.P.1    Messier, C.2    De Boer, P.3    Westerink, B.H.C.4
  • 43
    • 77957180502 scopus 로고
    • Accumulation of Cd(II) in the CNS depending on the route of administration: Intraperitoneal, intratracheal, or intranasal
    • Evans J, Hastings L. 1992. Accumulation of Cd(II) in the CNS depending on the route of administration: intraperitoneal, intratracheal, or intranasal. Fundam Appl Toxicol 19:275-278.
    • (1992) Fundam Appl Toxicol , vol.19 , pp. 275-278
    • Evans, J.1    Hastings, L.2
  • 44
    • 0035044397 scopus 로고    scopus 로고
    • The melanocortin melanocyte-stimulating hormone/adrenocorticotropin(4-10) decreases body fat in humans
    • Fehm HL, Smolnik R, Kern W, McGregor GP, Bickel U, Born J. 2001. The melanocortin melanocyte-stimulating hormone/adrenocorticotropin(4-10) decreases body fat in humans. J Clin Endocrinol Metab 86:1144-1148.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 1144-1148
    • Fehm, H.L.1    Smolnik, R.2    Kern, W.3    McGregor, G.P.4    Bickel, U.5    Born, J.6
  • 45
    • 0025736120 scopus 로고
    • Insulin stimulates membrane phospholipid metabolism by enhancing endogenous alpha1-adrenergic activity in the rat hippocampus
    • Figlewicz DP, Szot P. 1991. Insulin stimulates membrane phospholipid metabolism by enhancing endogenous alpha1-adrenergic activity in the rat hippocampus. Brain Res 550:101-107.
    • (1991) Brain Res , vol.550 , pp. 101-107
    • Figlewicz, D.P.1    Szot, P.2
  • 46
    • 0025230913 scopus 로고
    • Insulin stimulates inositol incorporation in hippocampus of lean but not obese Zucker rats
    • Figlewicz DP, Szot P, Greenwood MRC. 1990. Insulin stimulates inositol incorporation in hippocampus of lean but not obese Zucker rats. Physiol Behav 47:325-330.
    • (1990) Physiol Behav , vol.47 , pp. 325-330
    • Figlewicz, D.P.1    Szot, P.2    Greenwood, M.R.C.3
  • 47
    • 0030583628 scopus 로고    scopus 로고
    • Diabetes causes differential changes in CNS noradrenergic and dopaminergic neurons in the rat: A molecular study
    • Figlewicz DP, Brot MD, McCall AL, Szot P. 1996. Diabetes causes differential changes in CNS noradrenergic and dopaminergic neurons in the rat: a molecular study. Brain Res 736:54-60.
    • (1996) Brain Res , vol.736 , pp. 54-60
    • Figlewicz, D.P.1    Brot, M.D.2    McCall, A.L.3    Szot, P.4
  • 48
    • 0025134934 scopus 로고
    • Characteristics of learning and memory in streptozocin-induced diabetic mice
    • Flood JF, Mooradian AD, Morley JE. 1990. Characteristics of learning and memory in streptozocin-induced diabetic mice. Diabetes 39:1391-1398.
    • (1990) Diabetes , vol.39 , pp. 1391-1398
    • Flood, J.F.1    Mooradian, A.D.2    Morley, J.E.3
  • 50
    • 0033378682 scopus 로고    scopus 로고
    • A disturbance in the neuronal insulin receptor signal transduction in sporadic Alzheimer's disease
    • Frolich L, Blum-Degen D, Riederer P, Hoyer S. 1999. A disturbance in the neuronal insulin receptor signal transduction in sporadic Alzheimer's disease. Ann NY Acad Sci 893:290-293.
    • (1999) Ann NY Acad Sci , vol.893 , pp. 290-293
    • Frolich, L.1    Blum-Degen, D.2    Riederer, P.3    Hoyer, S.4
  • 51
    • 0035871641 scopus 로고    scopus 로고
    • Stimulation of beta-amyloid precursor protein trafficking by insulin reduces intraneuronal beta-amyloid and requires mitogen-activated protein kinase signaling
    • Gasparini L, Gouras GK, Wang R, Gross RS, Beal MF, Greengard P, Xu H. 2001. Stimulation of beta-amyloid precursor protein trafficking by insulin reduces intraneuronal beta-amyloid and requires mitogen-activated protein kinase signaling. J Neurosci 21:2561-2570.
    • (2001) J Neurosci , vol.21 , pp. 2561-2570
    • Gasparini, L.1    Gouras, G.K.2    Wang, R.3    Gross, R.S.4    Beal, M.F.5    Greengard, P.6    Xu, H.7
  • 53
  • 54
    • 0026595846 scopus 로고
    • Tau proteins of Alzheimer paired helical filaments: Abnormal phosphorylation of all six brain isoforms
    • Goedert M, Spillantini MG, Cairns NJ, Crowther RA. 1992. Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms. Neuron 8:159-168.
    • (1992) Neuron , vol.8 , pp. 159-168
    • Goedert, M.1    Spillantini, M.G.2    Cairns, N.J.3    Crowther, R.A.4
  • 56
    • 0032559610 scopus 로고    scopus 로고
    • Effects of feeding and insulin on extracellular acetylcholine in the amygdala of freely moving rats
    • Hajnal A, Pothos EN, Lenard L, Hoebel BG. 1998. Effects of feeding and insulin on extracellular acetylcholine in the amygdala of freely moving rats. Brain Res 785:41-48.
    • (1998) Brain Res , vol.785 , pp. 41-48
    • Hajnal, A.1    Pothos, E.N.2    Lenard, L.3    Hoebel, B.G.4
  • 57
    • 0019163458 scopus 로고
    • Endogenous potentials generated in the hippocampal formation and amygdala by infrequent events
    • Halgren E, Squires NK, Wilson CL, Rohrbaugh JW, Babb TL, Crandall PH. 1980. Endogenous potentials generated in the hippocampal formation and amygdala by infrequent events. Science 210:803-805.
    • (1980) Science , vol.210 , pp. 803-805
    • Halgren, E.1    Squires, N.K.2    Wilson, C.L.3    Rohrbaugh, J.W.4    Babb, T.L.5    Crandall, P.H.6
  • 58
    • 0026338638 scopus 로고
    • Olfactory primary neurons as a route of entry for toxic agents into the CNS
    • Hastings L, Evans JE. 1991. Olfactory primary neurons as a route of entry for toxic agents into the CNS. Neurotoxicology 12:707-714.
    • (1991) Neurotoxicology , vol.12 , pp. 707-714
    • Hastings, L.1    Evans, J.E.2
  • 59
    • 0028263437 scopus 로고
    • Short-term or long-term intracerebroventricular (i.e.v.) infusion of insulin exhibits a discrete anabolic effect on cerebral energy metabolism in the rat
    • Henneberg N, Hoyer S. 1994. Short-term or long-term intracerebroventricular (i.e.v.) infusion of insulin exhibits a discrete anabolic effect on cerebral energy metabolism in the rat. Neurosci Lett 175:153-156.
    • (1994) Neurosci Lett , vol.175 , pp. 153-156
    • Henneberg, N.1    Hoyer, S.2
  • 60
    • 0030748390 scopus 로고    scopus 로고
    • Insulin and insulin-like growth factor-1 regulate tau phosphorylation in cultured human neurons
    • Hong M, Lee VMY. 1997. Insulin and insulin-like growth factor-1 regulate tau phosphorylation in cultured human neurons. J Biol Chem 272:19547.
    • (1997) J Biol Chem , vol.272 , pp. 19547
    • Hong, M.1    Lee, V.M.Y.2
  • 61
    • 0031928535 scopus 로고    scopus 로고
    • Is sporadic Alzheimer disease the brain type of non-insulin dependent diabetes mellitus? A challenging hypothesis
    • Hoyer S. 1998. Is sporadic Alzheimer disease the brain type of non-insulin dependent diabetes mellitus? A challenging hypothesis. J Neural Transm 105:415-422.
    • (1998) J Neural Transm , vol.105 , pp. 415-422
    • Hoyer, S.1
  • 62
    • 0025856239 scopus 로고
    • Predominant abnormality in cerebral glucose utilization in late-onset dementia of the Alzheimer type: A cross-sectional comparison against advanced late-onset and incipient early-onset cases
    • Hoyer S, Nitsch R, Oesterreich K. 1991. Predominant abnormality in cerebral glucose utilization in late-onset dementia of the Alzheimer type: a cross-sectional comparison against advanced late-onset and incipient early-onset cases. J Neural Transm Park Dis Dement Sect 3:1-14.
    • (1991) J Neural Transm Park Dis Dement Sect , vol.3 , pp. 1-14
    • Hoyer, S.1    Nitsch, R.2    Oesterreich, K.3
  • 63
    • 0034095651 scopus 로고    scopus 로고
    • Transport of drugs from the nasal cavity to the central nervous system
    • Illum L. 2000. Transport of drugs from the nasal cavity to the central nervous system. Eur J Pharm Sci 11:1-18.
    • (2000) Eur J Pharm Sci , vol.11 , pp. 1-18
    • Illum, L.1
  • 64
    • 0026664249 scopus 로고
    • Intranasal insulin. Clinical pharmacokinetics
    • Illum L, Davis SS. 1992. Intranasal insulin. Clinical pharmacokinetics. Clin Pharmacokinet 23:30-41.
    • (1992) Clin Pharmacokinet , vol.23 , pp. 30-41
    • Illum, L.1    Davis, S.S.2
  • 65
    • 0026767381 scopus 로고
    • Insulin protects brain tissue against focal ischemia in rats
    • Izumi Y, Pinard E, Roussel S, Seylaz J. 1992. Insulin protects brain tissue against focal ischemia in rats. Neurosci Lett 144:121-123.
    • (1992) Neurosci Lett , vol.144 , pp. 121-123
    • Izumi, Y.1    Pinard, E.2    Roussel, S.3    Seylaz, J.4
  • 66
    • 0026066215 scopus 로고
    • Distribution of hippocampal CA1 and subicular efferents in the prefrontal cortex of the rat studied by means of anterograde transport of Phaseolus vulgaris-leucoagglutinin
    • Jay TM, Witter MP. 1991. Distribution of hippocampal CA1 and subicular efferents in the prefrontal cortex of the rat studied by means of anterograde transport of Phaseolus vulgaris-leucoagglutinin. J Comp Neurol 313:574-586.
    • (1991) J Comp Neurol , vol.313 , pp. 574-586
    • Jay, T.M.1    Witter, M.P.2
  • 67
    • 0010865793 scopus 로고
    • Human auditory evoked potentials: Possible brainstem components detected on the scalp
    • Jewett DL, Romano MN, Williston JS. 1970. Human auditory evoked potentials: possible brainstem components detected on the scalp. Science 94:681-696.
    • (1970) Science , vol.94 , pp. 681-696
    • Jewett, D.L.1    Romano, M.N.2    Williston, J.S.3
  • 68
    • 0025441770 scopus 로고
    • Acetazolamide and insulin alter choroid plexus epithelial cell (Na), pH and volume
    • Johanson CE, Murphy VA. 1990. Acetazolamide and insulin alter choroid plexus epithelial cell (Na), pH and volume. Am J Physiol 258:F1538-F1546.
    • (1990) Am J Physiol , vol.258
    • Johanson, C.E.1    Murphy, V.A.2
  • 69
    • 0032893770 scopus 로고    scopus 로고
    • Hippocampal synaptic plasticity in streptozotocin-diabetic rats: Impairment of long-term potentiation and facilitation of long-term depression
    • Kamal A, Biessels GJ, Urban IJ, Gispen WH. 1999. Hippocampal synaptic plasticity in streptozotocin-diabetic rats: impairment of long-term potentiation and facilitation of long-term depression Neuroscience 90:737-745.
    • (1999) Neuroscience , vol.90 , pp. 737-745
    • Kamal, A.1    Biessels, G.J.2    Urban, I.J.3    Gispen, W.H.4
  • 70
    • 2342536173 scopus 로고    scopus 로고
    • Learning and hippocampal synaptic plasticity in streptozotocin-diabetic rats: Interaction of diabetes and ageing
    • Kamal A, Biessels GJ, Duis SE, Gispen WH. 2000. Learning and hippocampal synaptic plasticity in streptozotocin-diabetic rats: interaction of diabetes and ageing. Diabetologia 43:500-506.
    • (2000) Diabetologia , vol.43 , pp. 500-506
    • Kamal, A.1    Biessels, G.J.2    Duis, S.E.3    Gispen, W.H.4
  • 71
    • 0000878179 scopus 로고
    • "P300" and memory: Individual differences in the von Restorff effect
    • Karis D, Fabiani M, Donchin E. 1984. "P300" and memory: individual differences in the von Restorff effect. Cogn Psychol 16:177-216.
    • (1984) Cogn Psychol , vol.16 , pp. 177-216
    • Karis, D.1    Fabiani, M.2    Donchin, E.3
  • 72
    • 0025103638 scopus 로고
    • Differential effects of human and pork insulin-induced hypoglycemia on neuronal functions in humans
    • Kern W, Lieb K, Kerner W, Born J, Fehm HL. 1990. Differential effects of human and pork insulin-induced hypoglycemia on neuronal functions in humans. Diabetes 39:1091-1098.
    • (1990) Diabetes , vol.39 , pp. 1091-1098
    • Kern, W.1    Lieb, K.2    Kerner, W.3    Born, J.4    Fehm, H.L.5
  • 73
    • 0028023126 scopus 로고
    • Effects of insulin and hypoglycemia on the auditory brainstem response in humans
    • Kern W, Kerner W, Pietrowsky R, Fehm HL, Born J. 1994a. Effects of insulin and hypoglycemia on the auditory brainstem response in humans. J Neurophysiol 72:678-683.
    • (1994) J Neurophysiol , vol.72 , pp. 678-683
    • Kern, W.1    Kerner, W.2    Pietrowsky, R.3    Fehm, H.L.4    Born, J.5
  • 75
    • 0030893810 scopus 로고    scopus 로고
    • Evidence for central nervous effects of corticotropin-releasing-hormone on gastric acid secretion in humans
    • Kern W, Schiefer B, Schwarzenburg J, Stange EF, Born J, Fehm HL. 1997. Evidence for central nervous effects of corticotropin-releasing-hormone on gastric acid secretion in humans. Neuroendocrinology 65:291-298.
    • (1997) Neuroendocrinology , vol.65 , pp. 291-298
    • Kern, W.1    Schiefer, B.2    Schwarzenburg, J.3    Stange, E.F.4    Born, J.5    Fehm, H.L.6
  • 76
    • 0033014163 scopus 로고    scopus 로고
    • Central nervous system effects of intranasally administered insulin during euglycemia in humans
    • Kern W, Born J, Schreiber H, Fehm HL. 1999. Central nervous system effects of intranasally administered insulin during euglycemia in humans. Diabetes 48:557-563.
    • (1999) Diabetes , vol.48 , pp. 557-563
    • Kern, W.1    Born, J.2    Schreiber, H.3    Fehm, H.L.4
  • 78
    • 0025737829 scopus 로고
    • Spread of the CVS strain of rabies virus and of the avirulent mutant AvO1 along the olfactory pathways of the mouse after intranasal inoculation
    • Lafay F, Coulon P, Astic L, Saucier D, Riche D, Holley A, Flamand A. 1991. Spread of the CVS strain of rabies virus and of the avirulent mutant AvO1 along the olfactory pathways of the mouse after intranasal inoculation. Virology 183:320-330.
    • (1991) Virology , vol.183 , pp. 320-330
    • Lafay, F.1    Coulon, P.2    Astic, L.3    Saucier, D.4    Riche, D.5    Holley, A.6    Flamand, A.7
  • 79
    • 0023813330 scopus 로고
    • DC-potential shifts and regional blood flow reveal frontal cortex involvement in human visuomotor learning
    • Lang W, Lang M, Podreka I, Steiner M, Uhl F, Suess E, Müller Ch, Deecke L. 1988. DC-potential shifts and regional blood flow reveal frontal cortex involvement in human visuomotor learning. Exp Brain Res 71:353-364.
    • (1988) Exp Brain Res , vol.71 , pp. 353-364
    • Lang, W.1    Lang, M.2    Podreka, I.3    Steiner, M.4    Uhl, F.5    Suess, E.6    Müller, Ch.7    Deecke, L.8
  • 80
    • 0031797937 scopus 로고    scopus 로고
    • Intracerebroventricular administration of streptozotocin causes long-term diminutions in learning and memory abilities and in cerebral energy metabolism in adult rats
    • Lannert H, Hoyer S. 1998. Intracerebroventricular administration of streptozotocin causes long-term diminutions in learning and memory abilities and in cerebral energy metabolism in adult rats. Behav Neurosci 112:1199-1208.
    • (1998) Behav Neurosci , vol.112 , pp. 1199-1208
    • Lannert, H.1    Hoyer, S.2
  • 81
    • 0034638270 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 and insulin mediate transient site-selective increases in tau phosphorylation in primary cortical neurons
    • Lesort M, Johnson GV. 2000. Insulin-like growth factor-1 and insulin mediate transient site-selective increases in tau phosphorylation in primary cortical neurons. Neuroscience 99:305-316.
    • (2000) Neuroscience , vol.99 , pp. 305-316
    • Lesort, M.1    Johnson, G.V.2
  • 82
    • 0032955426 scopus 로고    scopus 로고
    • Insulin transiently increases tau phosphorylation: Involvement of glycogen synthase kinase-3beta and Fyn tyrosine kinase
    • Lesort M, Jope RS, Johnson GV. 1999. Insulin transiently increases tau phosphorylation: involvement of glycogen synthase kinase-3beta and Fyn tyrosine kinase. J Neurochem 72:576-584.
    • (1999) J Neurochem , vol.72 , pp. 576-584
    • Lesort, M.1    Jope, R.S.2    Johnson, G.V.3
  • 84
    • 0029000105 scopus 로고
    • Insulin potentiates N-methyl-D-aspartate receptor activity in Xenopus oocytes and rat hippocampus
    • Liu L, Brown JC, Webster W, Morisett RA, Monaghan DT. 1995. Insulin potentiates N-methyl-D-aspartate receptor activity in Xenopus oocytes and rat hippocampus. Neurosci Lett 192:5-8.
    • (1995) Neurosci Lett , vol.192 , pp. 5-8
    • Liu, L.1    Brown, J.C.2    Webster, W.3    Morisett, R.A.4    Monaghan, D.T.5
  • 85
    • 0034457507 scopus 로고    scopus 로고
    • Impairment and recovery of elementary cognitive function induced by hypoglycemia in type-1 diabetic patients and healthy controls
    • Lobmann R, Smid HG, Pottag G, Wagner K, Heinze HJ, Lehnert H. 2000. Impairment and recovery of elementary cognitive function induced by hypoglycemia in type-1 diabetic patients and healthy controls. J Clin Endocrinol Metab 85:2758-2766.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 2758-2766
    • Lobmann, R.1    Smid, H.G.2    Pottag, G.3    Wagner, K.4    Heinze, H.J.5    Lehnert, H.6
  • 86
    • 0026529163 scopus 로고
    • Complex maze performance in young and aged rats: Response to glucose treatment and relationship to blood insulin and glucose
    • Long JM, Davis BJ, Garofalo P, Spangler EL, Ingram DK. 1992. Complex maze performance in young and aged rats: response to glucose treatment and relationship to blood insulin and glucose. Physiol Behav 51:411-418.
    • (1992) Physiol Behav , vol.51 , pp. 411-418
    • Long, J.M.1    Davis, B.J.2    Garofalo, P.3    Spangler, E.L.4    Ingram, D.K.5
  • 88
    • 0032781059 scopus 로고    scopus 로고
    • Increased cortisol levels and impaired cognition in human aging: Implication for depression and dementia in later life
    • Lupien SJ, Nair NP, Briere S, Maheu F, Tu MT, Lemay M, McEwen BS, Meaney MJ, 1999. Increased cortisol levels and impaired cognition in human aging: implication for depression and dementia in later life. Rev Neurosci 10:117-139.
    • (1999) Rev Neurosci , vol.10 , pp. 117-139
    • Lupien, S.J.1    Nair, N.P.2    Briere, S.3    Maheu, F.4    Tu, M.T.5    Lemay, M.6    McEwen, B.S.7    Meaney, M.J.8
  • 89
    • 0034122617 scopus 로고    scopus 로고
    • LTP mechanisms: From silence to four-lane traffic
    • Malinow R, Mainen ZF, Hayashi Y. 2000. LTP mechanisms: from silence to four-lane traffic. Curr Opin Neurobiol 10:352-357.
    • (2000) Curr Opin Neurobiol , vol.10 , pp. 352-357
    • Malinow, R.1    Mainen, Z.F.2    Hayashi, Y.3
  • 90
    • 0027364185 scopus 로고
    • Glucose enhancement of memory in patients with probable senile dementia of the Alzheimer type
    • Manning C, Ragozzino M, Gold PE. 1993. Glucose enhancement of memory in patients with probable senile dementia of the Alzheimer type. Neurobiol Aging 14:523.
    • (1993) Neurobiol Aging , vol.14 , pp. 523
    • Manning, C.1    Ragozzino, M.2    Gold, P.E.3
  • 91
    • 0025301069 scopus 로고
    • Effect of hyperinsulinemia on local cerebral insulin binding and glucose utilization in normoglycemic awake rats
    • Marfaing P, Penicaud L, Broer Y, Mraovitch S, Calando Y, Picon L. 1990. Effect of hyperinsulinemia on local cerebral insulin binding and glucose utilization in normoglycemic awake rats. Neurosci Lett 115:279.
    • (1990) Neurosci Lett , vol.115 , pp. 279
    • Marfaing, P.1    Penicaud, L.2    Broer, Y.3    Mraovitch, S.4    Calando, Y.5    Picon, L.6
  • 93
    • 0024990390 scopus 로고
    • Effects of changes in peripheral and cerebral glucose metabolism on locomotor activity, learning and memory in adult male rats
    • Mayer G, Nitsch R, Hoyer S. 1990. Effects of changes in peripheral and cerebral glucose metabolism on locomotor activity, learning and memory in adult male rats. Brain Res 532:95-100.
    • (1990) Brain Res , vol.532 , pp. 95-100
    • Mayer, G.1    Nitsch, R.2    Hoyer, S.3
  • 94
    • 0024217486 scopus 로고
    • Glucocorticoid receptors in the brain
    • McEwen B, 1988. Glucocorticoid receptors in the brain. Hosp Prac 23:107-121.
    • (1988) Hosp Prac , vol.23 , pp. 107-121
    • McEwen, B.1
  • 95
    • 0026648399 scopus 로고
    • Event related potentials and EEG components in a semantic memory search task
    • Mecklinger A, Kramer AF, Strayer DL. 1992. Event related potentials and EEG components in a semantic memory search task. Psychophysiology 29:104-119.
    • (1992) Psychophysiology , vol.29 , pp. 104-119
    • Mecklinger, A.1    Kramer, A.F.2    Strayer, D.L.3
  • 96
    • 0027314683 scopus 로고
    • Alterations in glucose metabolism in patients with Alzheimer's disease
    • Meneilly GS, Hill A. 1993. Alterations in glucose metabolism in patients with Alzheimer's disease. J Am Geriatr Soc 41:710-714.
    • (1993) J Am Geriatr Soc , vol.41 , pp. 710-714
    • Meneilly, G.S.1    Hill, A.2
  • 97
    • 0028256162 scopus 로고
    • Insulin attenuates scopolamine-induced memory deficits
    • Messier C, Destrade C. 1994. Insulin attenuates scopolamine-induced memory deficits. Psychobiology 22:16-21.
    • (1994) Psychobiology , vol.22 , pp. 16-21
    • Messier, C.1    Destrade, C.2
  • 98
    • 0023276931 scopus 로고
    • Memory improvement by glucose, fructose, and two glucose analogs: A possible effect on peripheral glucose transport
    • Messier C, White NM. 1987. Memory improvement by glucose, fructose, and two glucose analogs: a possible effect on peripheral glucose transport. Behav Neural Biol 48:104-127.
    • (1987) Behav Neural Biol , vol.48 , pp. 104-127
    • Messier, C.1    White, N.M.2
  • 99
    • 0033621540 scopus 로고    scopus 로고
    • Abeta42-positive non-pyramidal neurons around amyloid plaques in Alzheimer's disease
    • Mochizuki A, Tamaoka A, Shimohata A, Komatsuzaki Y, Shoji S. 2000. Abeta42-positive non-pyramidal neurons around amyloid plaques in Alzheimer's disease. Lancet 355:42-43.
    • (2000) Lancet , vol.355 , pp. 42-43
    • Mochizuki, A.1    Tamaoka, A.2    Shimohata, A.3    Komatsuzaki, Y.4    Shoji, S.5
  • 100
    • 0023872780 scopus 로고
    • Axonal transport of Borna disease virus along olfactory pathways in spontaneously and experimentally infected rats
    • Morales JA, Herzog S, Kompter C, Frese K, Rott R. 1988. Axonal transport of Borna disease virus along olfactory pathways in spontaneously and experimentally infected rats. Med Microbiol Immunol Berl 177:51-68.
    • (1988) Med Microbiol Immunol Berl , vol.177 , pp. 51-68
    • Morales, J.A.1    Herzog, S.2    Kompter, C.3    Frese, K.4    Rott, R.5
  • 101
    • 0020215487 scopus 로고
    • Processing negativity: An evoked-potential reflection of selective attention
    • Näätänen R. 1982. Processing negativity: an evoked-potential reflection of selective attention. Psychol Bull 92:605-640.
    • (1982) Psychol Bull , vol.92 , pp. 605-640
    • Näätänen, R.1
  • 102
    • 0023273689 scopus 로고
    • The N1 wave of the human electric and magnetic response to sound: A review and an analysis of the component structure
    • Näätänen R, Picton TW. 1987. The N1 wave of the human electric and magnetic response to sound: a review and an analysis of the component structure. Psychophysiology 24:375-425.
    • (1987) Psychophysiology , vol.24 , pp. 375-425
    • Näätänen, R.1    Picton, T.W.2
  • 104
    • 0022331624 scopus 로고
    • Memory search and visual spatial attention: An event related brain potential analysis
    • Okita T, Wijers AA, Mulder G, Mulder LJM. 1985. Memory search and visual spatial attention: an event related brain potential analysis. Acta Psychol 60:263-292.
    • (1985) Acta Psychol , vol.60 , pp. 263-292
    • Okita, T.1    Wijers, A.A.2    Mulder, G.3    Mulder, L.J.M.4
  • 105
    • 0024550536 scopus 로고
    • Effects of acute insulin deficiency on catecholamine and indolamine content and catecholamine turnover in microdissected hypothalamic nuclei in streptozotocin-diabetic rats
    • Oliver EH, Sartin JL, Dieberg G, Rahe CH, Marple DN, Kemppainen BJ. 1989. Effects of acute insulin deficiency on catecholamine and indolamine content and catecholamine turnover in microdissected hypothalamic nuclei in streptozotocin-diabetic rats. Acta Endocrinol (Copenh) 120:343-350.
    • (1989) Acta Endocrinol (Copenh) , vol.120 , pp. 343-350
    • Oliver, E.H.1    Sartin, J.L.2    Dieberg, G.3    Rahe, C.H.4    Marple, D.N.5    Kemppainen, B.J.6
  • 107
    • 0034938160 scopus 로고    scopus 로고
    • Cognitive effects of insulin in the central nervous system
    • Park CR. 2001. Cognitive effects of insulin in the central nervous system. Neurosci Biobehav Rev 25:311-323.
    • (2001) Neurosci Biobehav Rev , vol.25 , pp. 311-323
    • Park, C.R.1
  • 108
    • 0034012731 scopus 로고    scopus 로고
    • Intracerebroventricular insulin enhances memory in a passive-avoidance task
    • Park CR, Seeley RJ, Craft S, Woods SC. 2000. Intracerebroventricular insulin enhances memory in a passive-avoidance task. Physiol Behav 68:509-514.
    • (2000) Physiol Behav , vol.68 , pp. 509-514
    • Park, C.R.1    Seeley, R.J.2    Craft, S.3    Woods, S.C.4
  • 109
    • 0023180593 scopus 로고
    • Norepinephrine release from PVN and lateral hypothalamus during perfusion with 2-DG or insulin in the sated and fasted rat
    • Peinado JM, Meyers BD. 1991, Norepinephrine release from PVN and lateral hypothalamus during perfusion with 2-DG or insulin in the sated and fasted rat. Pharmacol Biochem Behav 27:715-721.
    • (1991) Pharmacol Biochem Behav , vol.27 , pp. 715-721
    • Peinado, J.M.1    Meyers, B.D.2
  • 110
    • 0031838478 scopus 로고    scopus 로고
    • Which event-related potentials reflect memory processing in a digit-probe identification task?
    • Pelosi L, Hayward M, Blumhardt LD. 1998. Which event-related potentials reflect memory processing in a digit-probe identification task? Cogn Brain Res 6:205-218.
    • (1998) Cogn Brain Res , vol.6 , pp. 205-218
    • Pelosi, L.1    Hayward, M.2    Blumhardt, L.D.3
  • 111
    • 0034038036 scopus 로고    scopus 로고
    • Degradation of soluble amyloid beta-peptides 1-40, 1-42, and the Dutch variant 1-40Q by insulin degrading enzyme from Alzheimer disease and control brains
    • Perez A, Morelli L, Cresto JC, Castano EM. 2000. Degradation of soluble amyloid beta-peptides 1-40, 1-42, and the Dutch variant 1-40Q by insulin degrading enzyme from Alzheimer disease and control brains. Neurochem Res 25:247-255.
    • (2000) Neurochem Res , vol.25 , pp. 247-255
    • Perez, A.1    Morelli, L.2    Cresto, J.C.3    Castano, E.M.4
  • 112
    • 0023091678 scopus 로고
    • Uptake of aluminium into central nervous system along nasal-olfactory pathways
    • Perl DP, Good PF. 1987. Uptake of aluminium into central nervous system along nasal-olfactory pathways. Lancet i:1028.
    • (1987) Lancet , vol.1 , pp. 1028
    • Perl, D.P.1    Good, P.F.2
  • 113
    • 0025000862 scopus 로고
    • Effect of olfactory bulb ablation on spread of a neurotropic coronavirus into the mouse brain
    • Perlman S, Evans C, Afifi A. 1990. Effect of olfactory bulb ablation on spread of a neurotropic coronavirus into the mouse brain. J Exp Med 172:1127-1132.
    • (1990) J Exp Med , vol.172 , pp. 1127-1132
    • Perlman, S.1    Evans, C.2    Afifi, A.3
  • 115
    • 0002844183 scopus 로고    scopus 로고
    • Functional evidence for a transmission of peptides along the olfactory systems into the brain in healthy humans
    • Krisch B, Mentlein R, editors. Basel: Birkhäuser
    • Pietrowsky R, Born J, Kern W, Fehm HL. 1996a. Functional evidence for a transmission of peptides along the olfactory systems into the brain in healthy humans. In: Krisch B, Mentlein R, editors. The peptidergic neuron. Basel: Birkhäuser. p 291-296.
    • (1996) The peptidergic neuron , pp. 291-296
    • Pietrowsky, R.1    Born, J.2    Kern, W.3    Fehm, H.L.4
  • 116
    • 0030209441 scopus 로고    scopus 로고
    • A nose-brain pathway for psychotropic peptides: Evidence from a brain evoked potential study with cholecystokinin
    • Pietrowsky R, Thiemann A, Kern W, Fehm HL, Born J. 1996b. A nose-brain pathway for psychotropic peptides: evidence from a brain evoked potential study with cholecystokinin. Psychoneuroendocrinology 21:559-572.
    • (1996) Psychoneuroendocrinology , vol.21 , pp. 559-572
    • Pietrowsky, R.1    Thiemann, A.2    Kern, W.3    Fehm, H.L.4    Born, J.5
  • 117
    • 0027304893 scopus 로고
    • Action of the diabetogenic drug streptozotocin on glycolytic metabolism in adult brain and hippocampus
    • Plaschke K, Hoyer S. 1993. Action of the diabetogenic drug streptozotocin on glycolytic metabolism in adult brain and hippocampus. Int J Dev Neurosci 11:477-483.
    • (1993) Int J Dev Neurosci , vol.11 , pp. 477-483
    • Plaschke, K.1    Hoyer, S.2
  • 119
    • 0014041263 scopus 로고
    • Modification of sensory cortical evoked potentials by hippocampal stimulation
    • Redding EK. 1967. Modification of sensory cortical evoked potentials by hippocampal stimulation. Electroenceph Clin Neurophysiol 22:74-83.
    • (1967) Electroenceph Clin Neurophysiol , vol.22 , pp. 74-83
    • Redding, E.K.1
  • 123
    • 0025281828 scopus 로고
    • Homeostatic disruption and memory: Effect of insulin administration in rats
    • Santucci AC, Schroeder H, Riccio DC. 1990. Homeostatic disruption and memory: effect of insulin administration in rats. Behav Neural Biol 53:321-333.
    • (1990) Behav Neural Biol , vol.53 , pp. 321-333
    • Santucci, A.C.1    Schroeder, H.2    Riccio, D.C.3
  • 127
    • 0033046817 scopus 로고    scopus 로고
    • Transgenic animals relevant to Alzheimer's disease
    • Seabrook GR, Rosahl TW. 1999. Transgenic animals relevant to Alzheimer's disease. Neuropharmacology 38:1-17.
    • (1999) Neuropharmacology , vol.38 , pp. 1-17
    • Seabrook, G.R.1    Rosahl, T.W.2
  • 128
    • 0027935380 scopus 로고
    • Nasal absorption of zidovudine and its transport to cerebrospinal fluid
    • Seki T, Sato N, Hasegawa T, Kawaguchi T, Juni K. 1994. Nasal absorption of zidovudine and its transport to cerebrospinal fluid. Biol Pharm Bull 17:1135-1137.
    • (1994) Biol Pharm Bull , vol.17 , pp. 1135-1137
    • Seki, T.1    Sato, N.2    Hasegawa, T.3    Kawaguchi, T.4    Juni, K.5
  • 129
    • 0026569554 scopus 로고
    • Kinetics of virus spread and changes in levels of several cytokine mRNAs in the brain after intranasal infection of rats with Borna disease virus
    • Shankar V, Kao M, Hamir AN, Sheng H, Koprowski H, Dietzschold B. 1992. Kinetics of virus spread and changes in levels of several cytokine mRNAs in the brain after intranasal infection of rats with Borna disease virus. J Virol 66:992-998.
    • (1992) J Virol , vol.66 , pp. 992-998
    • Shankar, V.1    Kao, M.2    Hamir, A.N.3    Sheng, H.4    Koprowski, H.5    Dietzschold, B.6
  • 130
    • 0026086053 scopus 로고
    • Short-term action of insulin on Aplysia neurons: Generation of a possible novel modulator of ion channels
    • Shapiro E, Brown SD, Saltiel AR, Schwartz JH. 1991. Short-term action of insulin on Aplysia neurons: generation of a possible novel modulator of ion channels. J Neurobiol 22:55-62.
    • (1991) J Neurobiol , vol.22 , pp. 55-62
    • Shapiro, E.1    Brown, S.D.2    Saltiel, A.R.3    Schwartz, J.H.4
  • 131
    • 0022614842 scopus 로고
    • Inhibitory action of insulin on suprachiasmatic nucleus neurons in rat hypothalamic slice preparation
    • Shibata S, Liou SY, Ueki S, Oomura Y. 1985. Inhibitory action of insulin on suprachiasmatic nucleus neurons in rat hypothalamic slice preparation. Physiol Behav 36:79-81.
    • (1985) Physiol Behav , vol.36 , pp. 79-81
    • Shibata, S.1    Liou, S.Y.2    Ueki, S.3    Oomura, Y.4
  • 132
    • 0030292912 scopus 로고    scopus 로고
    • Event-related potentials in the dorsal hippocampus of rats during an auditory discrimination task
    • Shinba T, Andow Y, Shinozaki T, Ozawa N, Yamamoto K. 1996. Event-related potentials in the dorsal hippocampus of rats during an auditory discrimination task. Electroenceph Clin Neurophysiol 100:563-568.
    • (1996) Electroenceph Clin Neurophysiol , vol.100 , pp. 563-568
    • Shinba, T.1    Andow, Y.2    Shinozaki, T.3    Ozawa, N.4    Yamamoto, K.5
  • 133
    • 0026554104 scopus 로고    scopus 로고
    • Attempts to make models for Alzheimer's disease
    • Shiosaka S. 1999. Attempts to make models for Alzheimer's disease. Neurosci Res 13:237.
    • (1999) Neurosci Res , vol.13 , pp. 237
    • Shiosaka, S.1
  • 136
    • 0026847039 scopus 로고
    • Memory and the hippocampus: A synthesis of findings with rats, monkeys and humans
    • Squire LR. 1992. Memory and the hippocampus: a synthesis of findings with rats, monkeys and humans. Psychol Rev 99:195.
    • (1992) Psychol Rev , vol.99 , pp. 195
    • Squire, L.R.1
  • 137
    • 0023747694 scopus 로고
    • Penetration of peripheral glucose and insulin into cerebrospinal fluid in rats
    • Steffens AB, Scheurink AJ, Porte D Jr, Woods SC. 1988. Penetration of peripheral glucose and insulin into cerebrospinal fluid in rats. Am J Physiol 255:R200-R204.
    • (1988) Am J Physiol , vol.255
    • Steffens, A.B.1    Scheurink, A.J.2    Porte D., Jr.3    Woods, S.C.4
  • 138
    • 0027404714 scopus 로고
    • Disinhibition of hippocampal pyramidal cells during the transition into theta rhythm
    • Stewart M. 1993. Disinhibition of hippocampal pyramidal cells during the transition into theta rhythm. Exp Brain Res 93:1-5.
    • (1993) Exp Brain Res , vol.93 , pp. 1-5
    • Stewart, M.1
  • 139
    • 0023696801 scopus 로고
    • Blood glucose and brain function: Interactions with CNS cholinergic systems
    • Stone WS, Cotrill KL, Walker DL, Gold PE. 1988. Blood glucose and brain function: interactions with CNS cholinergic systems. Behav Neural Biol 50:325.
    • (1988) Behav Neural Biol , vol.50 , pp. 325
    • Stone, W.S.1    Cotrill, K.L.2    Walker, D.L.3    Gold, P.E.4
  • 140
    • 0024382477 scopus 로고
    • Mercury poisoning from dental amalgam through a direct nose-brain transport
    • Stortebecker P. 1989. Mercury poisoning from dental amalgam through a direct nose-brain transport [Letter]. Lancet 1:1207-1207.
    • (1989) Lancet , vol.1 , pp. 1207
    • Stortebecker, P.1
  • 141
    • 0025342391 scopus 로고
    • Neurophysiological changes during insulin-induced hypoglycaemia and in the recovery period following glucose infusion in type I (insulin-dependent) diabetes mellitus and in normal man
    • Tallroth G, Lindgren M, Stenberg G, Rosen I, Agardh CD. 1990. Neurophysiological changes during insulin-induced hypoglycaemia and in the recovery period following glucose infusion in type I (insulin-dependent) diabetes mellitus and in normal man. Diabetologia 33:319-323.
    • (1990) Diabetologia , vol.33 , pp. 319-323
    • Tallroth, G.1    Lindgren, M.2    Stenberg, G.3    Rosen, I.4    Agardh, C.D.5
  • 144
    • 0030727302 scopus 로고    scopus 로고
    • Isolation of specific interference processing in the Stroop task: PET activation studies
    • Taylor SF, Kornblum S, Lauber EJ, Minoshima S, Koeppe RA. 1997. Isolation of specific interference processing in the Stroop task: PET activation studies. Neuroimage 6:81-92.
    • (1997) Neuroimage , vol.6 , pp. 81-92
    • Taylor, S.F.1    Kornblum, S.2    Lauber, E.J.3    Minoshima, S.4    Koeppe, R.A.5
  • 145
    • 0025847968 scopus 로고
    • Insulin receptors in the central nervous system: Localization, signalling mechanisms and functional aspects
    • Unger JW, Livingston JN, Moss AM. 1991. Insulin receptors in the central nervous system: localization, signalling mechanisms and functional aspects. Prog Neurobiol 36:343-362.
    • (1991) Prog Neurobiol , vol.36 , pp. 343-362
    • Unger, J.W.1    Livingston, J.N.2    Moss, A.M.3
  • 146
    • 0016830420 scopus 로고
    • Some connections of the entorinal (area 28) and perirhinal (area 35) cortices of the Rhesus monkey. II. Frontal lobe afferents
    • Van Hoesen GW, Macdougall JM, Mitchell JC. 1975. Some connections of the entorinal (area 28) and perirhinal (area 35) cortices of the Rhesus monkey. II. Frontal lobe afferents. Brain Res 95:25-38.
    • (1975) Brain Res , vol.95 , pp. 25-38
    • Van Hoesen, G.W.1    Macdougall, J.M.2    Mitchell, J.C.3
  • 147
    • 0020998384 scopus 로고
    • Circumventricular organs: Receptors and mediators of direct peptide hormone action on brain
    • Van Houten M, Posner BI. 1983. Circumventricular organs: receptors and mediators of direct peptide hormone action on brain. Adv Metab Disord 10:269-289.
    • (1983) Adv Metab Disord , vol.10 , pp. 269-289
    • Van Houten, M.1    Posner, B.I.2
  • 148
    • 0034161516 scopus 로고    scopus 로고
    • Neurons regulate extracellular levels of amyloid beta-protein via proteolysis by insulin-degrading enzyme
    • Vekrellis K, Ye Z, Qiu WQ, Walsh D, Hartley D, Chesneau V, Rosner MR, Selkoe DJ. 2000. Neurons regulate extracellular levels of amyloid beta-protein via proteolysis by insulin-degrading enzyme. J Neurosci 20:1657-1665.
    • (2000) J Neurosci , vol.20 , pp. 1657-1665
    • Vekrellis, K.1    Ye, Z.2    Qiu, W.Q.3    Walsh, D.4    Hartley, D.5    Chesneau, V.6    Rosner, M.R.7    Selkoe, D.J.8
  • 149
    • 0001848382 scopus 로고    scopus 로고
    • The hippocampus and the orienting reflex
    • Sokolov EN, Vinogradova OS, editors, Hilsdale: Erlbaum
    • Vinogradova OS. 1999. The hippocampus and the orienting reflex. In: Sokolov EN, Vinogradova OS, editors, Neuronal mechanisms of the orienting reflex. Hilsdale: Erlbaum. p 128-154.
    • (1999) Neuronal mechanisms of the orienting reflex , pp. 128-154
    • Vinogradova, O.S.1
  • 153
    • 0026948014 scopus 로고
    • Enhancing effect of cyclodextrins on nasal absorption of insulin and its duration in rabbits
    • Watanabe Y, Matsumoto Y, Kawamoto K, Yazawa S, Matsumoto M. 1992. Enhancing effect of cyclodextrins on nasal absorption of insulin and its duration in rabbits. Chem Pharm Bull 40:3100-3104.
    • (1992) Chem Pharm Bull , vol.40 , pp. 3100-3104
    • Watanabe, Y.1    Matsumoto, Y.2    Kawamoto, K.3    Yazawa, S.4    Matsumoto, M.5
  • 154
    • 0032562694 scopus 로고    scopus 로고
    • Tracking insulin to the mind
    • Wickelgren I. 1998. Tracking insulin to the mind. Science 280:517-1519.
    • (1998) Science , vol.280 , pp. 517-1519
    • Wickelgren, I.1
  • 155
    • 0025642473 scopus 로고
    • A re-assessment of the regulation of adiposity and appetite by the brain insulin system
    • Woods SC, Figlewicz Lattemann DP, Schwartz MW, Porte D Jr. 1990. A re-assessment of the regulation of adiposity and appetite by the brain insulin system. Int J Obes 14(Suppl 3):69-73.
    • (1990) Int J Obes , vol.14 , Issue.SUPPL. 3 , pp. 69-73
    • Woods, S.C.1    Figlewicz Lattemann, D.P.2    Schwartz, M.W.3    Porte D., Jr.4
  • 156
    • 0035947044 scopus 로고    scopus 로고
    • Role of insulin and insulin receptor in learning and memory
    • Zhao WQ, Alkon DL. 2001. Role of insulin and insulin receptor in learning and memory. Mol Cell Endocrinol 177:125-134.
    • (2001) Mol Cell Endocrinol , vol.177 , pp. 125-134
    • Zhao, W.Q.1    Alkon, D.L.2
  • 157
    • 0033521130 scopus 로고    scopus 로고
    • Brain insulin receptors and spatial memory. Correlated changes in gene expression, tyrosine phosphorylation, and signaling molecules in the hippocampus of water maze trained rats
    • Zhao W, Chen H, Xu H, Moore E, Meiri N, Quon MJ, Alkon DL. 1999. Brain insulin receptors and spatial memory. Correlated changes in gene expression, tyrosine phosphorylation, and signaling molecules in the hippocampus of water maze trained rats. J Biol Chem 274:34893-34902.
    • (1999) J Biol Chem , vol.274 , pp. 34893-34902
    • Zhao, W.1    Chen, H.2    Xu, H.3    Moore, E.4    Meiri, N.5    Quon, M.J.6    Alkon, D.L.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.