Cellular expression of the immediate early transcription factors Nurr1 and NGFI-B suggests a gene regulatory role in several brain regions including the nigrostriatal dopamine system

Molecular Brain Research

Volumn 41, Issue 1-2, 1996, Pages 111-120

  Zetterström, Rolf H ^a   Williams, Reg ^a   Perlmann, Thomas ^a   Olson, Lars ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Immediate early gene; In situ hybridization; NGFI B; Nurr1; Orphan receptor; Transcription factor

Indexed keywords

MESSENGER RNA; TRANSCRIPTION FACTOR;

ANIMAL TISSUE; ARTICLE; BASAL GANGLION; BRAIN DEVELOPMENT; BRAIN REGION; CENTRAL NERVOUS SYSTEM; DOPAMINERGIC SYSTEM; EMBRYO; GENE CONTROL; IMMEDIATE EARLY GENE; MOUSE; NEWBORN; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; OLFACTORY BULB; PARKINSON DISEASE; PRIORITY JOURNAL; SUBSTANTIA NIGRA;

ANIMALIA;

EID: 0000190727     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0169-328X(96)00074-5     Document Type: Article

References (26)

1. Altman, J. and Bayer, S.A., Atlas of Prenatal Rat Brain Development, CRC Press, Boca Raton, FL, 1995.
2. Dagerlind Å., Friberg K., Bean A.J., Hökfelt T. Sensitive mRNA detection using unfixed tissue: combined radioactive and non-radioactive in situ hybridization histochemistry. Histochemistry. 98:1992;39-49.
3. Forman B.M., Umesono K., Chen J., Evans R.M. Unique response pathways are established by allosteric interactions among nuclear hormone receptors. Cell. 81:1995;541-550.
4. Glass C. Differential recognition of target genes by nuclear receptor monomers, dimers, and heterodimers. Endocrinol. Rev. 15:1994;391-407.
5. Grima B., Lamouroux A., Blanot F., Biguet N.F., Mallet J. Complete coding sequence of rat tyrosine hydroxylase mRNA, Proc. Natl. Acad. Sci. USA. 82:1985;617-621.
6. Hazel T.G., Nathans D., Lau L.F. A gene inducible by serum growth factors encodes a member of the steroid and thyroid hormone receptor family. Proc. Natl. Acad. Sci. USA. 85:1988;8444-8448.
7. Hazel T.G., Misra R., Davis I.J., Greenberg M.E., Lau L.F. Nur77 is differentially modified in PC12 cells upon membrane depolarization and growth factor treatment. Mol. Cell. Biol. 11:1991;3239-3246.
8. Honkaniemi J., Sagar S.M., Pyykonen I., Hicks K.J., Sharp F.R. Focal brain injury induces multiple immediate early genes encoding zinc finger transcription factors. Mol. Brain Res. 28:1995;157-163.
9. Kaufman, M.H. The Atlas of Mouse Development, Academic Press, San Diego, CA, 1992.
10. Kostrouch Z., Kostrouchova M., Rall J.E. Steroid/thyroid hormone receptor genes in. Caenorhabditis elegans, Proc. Natl. Acad. Sci. USA. 92:1995;156-159.
11. Law S.W., Conneely O.M., DeMayo F.J., O'Malley B.W. Identification of a new brain-specific transcription factor, NURR1, Mol. Endocrinol. 6:1992;2129-2135.
12. Lee S.L., Wesselschmidt R.L., Linette G.P., Kanagawa O., Russell J.H., Milbrandt J. Unimpaired thymic and peripheral T cell death in mice lacking the nuclear receptor NGFI-B (nurr77). Science. 269:1995;532-535.
13. Leid M., Kastner P., Chambon P. Multiplicity generates diversity in the retinoic acid signaling pathways. Trends Biochem. Sci. 17:1992;427-433.
14. Liu Z.-G., Smith S.W., McLaughlin K.A., Schwartz L.M., Osborne B.A. Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate-early gene nur77, Nature. 367:1994;281-284.
15. Milbrandt J. Nerve growth factor induces a gene homologous to the glucocorticoid receptor gene. Neuron. 1:1988;183-188.
16. Ohkura N., Hijikuro M., Yamamoto A., Miki K. Molecular cloning of a novel thyroid/steroid receptor superfamily gene from cultured rat neuronal cells. Biochem. Biophys. Res. Comm. 205:1994;1959-1965.
17. Olson L., Seiger A., Fuxe K. Heterogeneity of striatal and limbic dopamine innervation: highly fluorescent islands in developing and adult rats. Brain Res. 44:1972;283-288.
18. Paxinos, S. and Watson, C., The Rat Brain in Stereotaxic Coordinates, Academic Press, North Ryde, 1986.
19. Paxinos, G., Ashwell, K.W.S. and Törk, I., Atlas of the Developing Rat Nervous System. 2nd edn., Academic Press, San Diego, CA, 1994.
20. Perlmann T., Jansson L. A novel pathway for vitamin A signaling mediated by RXR heterodimerization with NGFI-B and Nurr1. Genes Dev. 9:1995;769-782.
21. Power R.F., Mani S.K., Codina J., Conneely O.M., O'Malley B.W. Dopaminergic and ligand-independent activation of steroid hormone receptors. Science. 254:1991;1636-1639.
22. Scearce L.M., Laz T.M., Hazel T.G., Lau L.F., Taub R. RNR-1, a nuclear receptor in the NGFI-B/Nur77 family that is rapidly induced in regenerating liver. J. Biol. Chem. 268:1993;8855-8861.
23. Sutherland J.D., Kozlova T., Tzertzinis G., Kafatos F.C. Drosophila hormone receptor 38: a second partner for drosophila usp suggests an unexpected role for nuclear receptors of the nerve growth factor-induced protein B type. Proc. Natl. Acad. Sci. USA. 92:1995;7966-7970.
24. Ungerstedt U., Arbuthnott G.W. Quantitative recording of rotational behaviour in rats after 6-hydroxydopamine lesions of the nigrostriatal dopamine system. Brain Res. 24:1970;485-493.
25. Wilson T.E., Mouw A.R., Weaver C.A., Milbrandt J., Parker K.L. The orphan nuclear receptor NGFI-B regulates expression of the gene encoding steroid 21-hydroxylase. Mol. Cell. Biol. 13:1993;861-868.
26. Woronicz J.D., Calnan B., Ngo V., Winoto A. Requirement for the orphan steroid receptor Nur77 in apoptosis of T-cell hybridomas. Nature. 367:1994;277-280.