Differential expression of inhibitory and activating CD94/NKG2 receptors on NK cell clones

Journal of Immunological Methods

Volumn 264, Issue 1-2, 2002, Pages 109-119

  Brostjan, Christine ^a   Belloón, Teresa ^b   Sobanov, Yuri ^c   López Botet, Miguel ^d   Hofer, Erhard ^c  

^a UNIVERSITY OF VIENNA   (Austria)

^b HOSPITAL UNIVERSITARIO DE LA PRINCESA   (Spain)

^c UNIVERSITY OF VIENNA   (Austria)

^d UNIVERSITAT POMPEU FABRA   (Spain)

Author keywords

Clonal expression; Natural killer cell; NK receptor; NKG2; Real time PCR; Transcript

Indexed keywords

CD94 ANTIGEN; HLA E ANTIGEN; MESSENGER RNA; NKG2 RECEPTOR; RECEPTOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL CLONE; CONTROLLED STUDY; CYTOTOXICITY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; NATURAL KILLER CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANTIBODY-DEPENDENT CELL CYTOTOXICITY; ANTIGENS, CD; ANTIGENS, CD94; CELL LINE; CLONE CELLS; CYTOTOXICITY TESTS, IMMUNOLOGIC; HUMANS; JURKAT CELLS; KILLER CELLS, NATURAL; LECTINS, C-TYPE; MEMBRANE GLYCOPROTEINS; PROTEIN ISOFORMS; RECEPTORS, IMMUNOLOGIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED;

EID: 0036606062     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-1759(02)00084-4     Document Type: Article

References (46)

1. MHC class I mosaic mice reveal insights into control of Ly49C inhibitory receptor expression in NK cells
2. A novel functional cell surface dimer (Kp43) expressed by natural killer cells and T cell receptor-gamma/delta+ T lymphocytes: I. Inhibition of the IL-2-dependent proliferation by anti-Kp43 monoclonal antibody
3. Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA
4. + T cell clone upon the aggregation of an activatory CD94/kp39 heterodimer
5. Increased expression of non-functional killer inhibitory receptor CD94 in CD8+ cells of myeloma patients
6. Recognition of human histocompatibility leukocyte antigen (HLA)-E complexed with HLA class I signal sequence-derived peptides by CD94/NKG2 confers protection from natural killer cell-mediated lysis
7. Regulation of NK cell functions through interaction of the CD94/NKG2 receptors with the nonclassical class I molecule HLA-E
8. HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C
9. NKG2A complexed with CD94 defines a novel inhibitory natural killer cell receptor
10. The NKG2 natural killer cell receptor family: Comparative analysis of promoter sequences
11. The centromeric part of the human NK gene complex: Linkage of LOX-1 and LY49L with the CD94/NKG2 region
12. Natural killer cell acceptance of H-2 mismatch bone marrow grafts in transgenic mice expressing HLA-Cw3 specific killer cell inhibitory receptor
13. The activating form of CD94 receptor complex: CD94 covalently associates with the Kp39 protein that represents the product of the NKG2-C gene
14. The CD94 and NKG2-A C-type lectins covalently assemble to form a natural killer cell inhibitory receptor for HLA class I molecules
15. Specific engagement of the CD94/NKG2-A killer inhibitory receptor by the HLA-E class Ib molecule induces SHP-1 phosphatase recruitment to tyrosine-phosphorylated NKG2-A: Evidence for receptor function in heterologous transfectants
16. Molecular characterization of human CD94: A type II membrane glycoprotein related to the C-type lectin superfamily
17. Molecular characterization of a gene in the rat homologous to human CD94
18. The genomic organization of NKG2C, E, F, and D receptor genes in the human natural killer gene complex
19. Characterization of a human cell line (NK-92) with phenotypical and functional characteristics of activated natural killer cells
20. Ly49A transgenic mice provide evidence for a major histocompatibility complex-dependent education process in natural killer cell development
21. The centromeric part of the human NK receptor complex: Lectin-like receptor genes expressed in NK, dendritic and endothelial cells
22. DNA sequence analysis of NKG2, a family of related cDNA clones encoding type II integral membrane proteins on human natural killer cells
23. Natural killer cell cytolytic activity is inhibited by NKG2-A and activated by NKG2-C
24. How to recognize a foreign submarine
25. A simple nested RT-PCR method for quantitation of the relative amounts of multiple cytokine mRNAs in small tissue samples
26. Association of DAP12 with activating CD94/NKG2C NK cell receptors
27. Human natural killer cell receptors involved in MHC class I recognition are disulfide-linked heterodimers of CD94 and NKG2 subunits
28. HLA-E is a major ligand for the natural killer inhibitory receptor CD94/NKG2A
29. HLA-E-bound peptides influence recognition by inhibitory and triggering CD94/NKG2 receptors: Preferential response to an HLA-G-derived nonamer
30. Cloning of murine NKG2A, B and C: Second family of C-type lectin receptors on murine NK cells
31. Paired inhibitory and triggering NK cell receptors for HLA class I molecules
32. Human NK-cell receptors
33. NK cell mediated recognition of HLA class Ib molecules: Role of CD94/NKG2 receptors
34. Developments in quantitative PCR
35. Cloning of NKG2-F, a new member of the NKG2 family of human natural killer cell receptor genes
36. Glyceraldehyde-3-phosphate dehydrogenase gene expression in human breast cancer
37. Characterization of a cell line, NKL, derived from an aggressive human natural killer cell leukemia
38. Disordered expression of inhibitory receptors on the NK1-type natural killer (NK) leukemic cells from patients with hypersensitivity to mosquito bites
39. Inhibitory CD94 molecules identified by the Z199 monoclonal antibody recognize different HLA-class I molecules
40. Linkage of the NKG2 and CD94 receptor genes to D12S77 in the human natural killer gene complex
41. Stochastic acquisition of Qa1 receptors during the development of fetal NK cells in vitro accounts in part but not in whole for the ability of these cells to distinguish between class I-sufficient and class I-deficient targets
42. Kinetics and peptide dependency of the binding of the inhibitory NK receptor CD94/NKG2-A and the activating receptor CD94/NKG2-C to HLA-E
43. Functionally and structurally distinct NK cell receptor repertoires in the peripheral blood of two human donors
44. Expression of CD94/NKG2 subtypes on tumor-infiltrating lymphocytes in primary and metastatic melanoma
45. Clonal analysis of NK cell development from bone marrow progenitors in vitro: Orderly acquisition of receptor gene expression
46. A multigene family on human chromosome 12 encodes natural killer-cell lectins