Regulation of NK cell functions through interaction of the CD94/NKG2 receptors with the nonclassical class I molecule HLA-E

Current Topics in Microbiology and Immunology

Volumn 244, Issue , 1999, Pages 85-95

  Braud, V M ^a   McMichael, A J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD94 ANTIGEN; HLA ANTIGEN; LYMPHOCYTE RECEPTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1;

ANTIGEN BINDING; HLA SYSTEM; HUMAN; LIGAND BINDING; MAJOR HISTOCOMPATIBILITY COMPLEX; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RECEPTOR BINDING; REVIEW;

EID: 0033011023     PISSN: 0070217X     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-642-58537-1_7     Document Type: Review

References (5)

1. Aldrich CJ, DeCloux A, Woods AS, Cotter RJ, Soloski MJ, Forman J (1994) Identification of a TAP-dependent leader peptide recognized by alloreactive T cells specific for a class Ib antigen. Cell 79: 649-658
2. Borrego F, Ulbrecht M, Weiss EH, Coligan JE, Brooks AG (1998) Recognition of human histocom-patibility leukocyte antigen (HLA)-E complexed with HLA class I signal sequence-derived peptides by CD94/NKG2 confers protection from NK-cell-mediated lysis. J Exp Med 187:813-818
3. Brand V, Jones EY, McMichael A (1997) The human major histocompatibilily complex class Ib molecule HLA-E binds signal sequence-derived peptides with primary anchor residues at positions 2 and 9. Eur J Immunol 27:1164-1169
4. Braud VM, Allan DSJ, O'Callaghan CA, Soderstrom K, D'Andrea A, Ogg GS, Lazetic S, Young NT, Bell JI, Phillips JH, Lanier LL, McMichael AJ (1998a) HLA-E binds to natural killer cell receptors CD94/NKG2 A, B, and C. Nature 391:795-799
5. Braud VM, Allan DSJ, Wilson D, McMichael AJ (1998b) TAP- and tapasin-dependent HLA-E surface expression correlates with the binding of an MHC class I leader peptide. Curr Biol 8:1-10