The genomic organization of NKG2C, E, F, and D receptor genes in the human natural killer gene complex

Immunogenetics

Volumn 48, Issue 3, 1998, Pages 163-173

  Glienke, Jens ^a   Sobanov, Yuri ^b   Brostjan, Christine ^b   Steffens, Christina ^a   Nguyen, Catherine ^c   Lehrach, Hans ^a   Hofer, Erhard ^b   Francis, Fiona ^a,d  

^a MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

^b UNIVERSITY OF VIENNA   (Austria)

^c INSERM   (France)

^d CHU Cochin Port Royal ^*  (France)

Author keywords

Chromosome 12; Genomic organization; Natural killer cells; NK complex; NKG2

Indexed keywords

MESSENGER RNA;

ARTICLE; DNA SEQUENCE; EXON; GENE STRUCTURE; GENETIC LINKAGE; GENOME; HUMAN; HUMAN CELL; MULTIGENE FAMILY; NATURAL KILLER CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RECEPTOR GENE; RESTRICTION MAPPING; SEQUENCE HOMOLOGY;

BASE SEQUENCE; CHROMOSOME MAPPING; DNA PRIMERS; DNA, COMPLEMENTARY; EVOLUTION, MOLECULAR; EXONS; GENOME, HUMAN; HUMANS; INTRONS; KILLER CELLS, NATURAL; LINKAGE (GENETICS); MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; POLYMERASE CHAIN REACTION; RECEPTORS, IMMUNOLOGIC; SEQUENCE HOMOLOGY, AMINO ACID; SEQUENCE HOMOLOGY, NUCLEIC ACID;

EID: 0031857513     PISSN: 00937711     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002510050420     Document Type: Article

References (43)

1. Adamkiewicz, T.V., McSherry, C., Bach, F.H., and Houchins, J.P. Natural killer lectin-like receptors have divergent carboxy-termini, distinct from C-type lectins. Immunogenetics 39: 218, 1994
2. Altschul, S.F., Gish, W., Miller, W., Myers, E.W., Lipman, D.J. Basic local alignment search tool. J Mol Biol 215:403-410, 1990
3. Biassoni, R., Cantoni, C., Falco, M., Verdani, S., Bottino, C., Vitale, M., Conte, R., Poggi, A., Moretta, A., and Moretta, L. The human leukocyte antigen (HLA)-C-specific "activatory" or "inhibitory" natural killer cell receptors display highly homologous extracellular domains but differ in their transmembrane and intracytoplasmic portions. J Exp Med 183: 645-650, 1996
4. Braud, V.M., Allan, D.S.J., O'Callaghan, C.A., Soderstrom, K., D'Andrea, A., Ogg, G.S., Lazetic, S., Young, N.T., Bell, J.I., Phillips, J.H., Lanier, L.L., and McMichael, A.J. HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C. Nature 391: 795-799, 1998
5. Brennan, J., Lemieux, S., Freeman, J.D., Mager, D.L., Takei, F. Heterogeneity among Ly-49 C natural killer (NK) cells: characterization of highly related receptors with differing functions and expression patterns. J Exp Med 184:2085-2090, 1996
6. Brooks, A.G., Posch, P.E., Scorzelli, C.J., Borrego, F., and Coligan, J.E. NKG2A complexed with CD94 defines a novel inhibitory natural killer cell receptor. J Exp Med 185: 795-800, 1997
7. Brown, M.G., Fulmek, S., Matsumoto, K., Cho, R., Lyons, P., Levy, E., Scalzo, A., and Yokoyama, W. A 2 Mb YAC contig and physical map of the natural killer cell gene complex on mouse chromosome Genomics 6: 16-25, 1997
8. Carretero, M., Cantoni, C., Bellon, T., Bottino, C., Biassoni, R., Rodriguez, A., Perez-Villar, J.J., Moretta, L., Moretta, A., Lopez-Botet, M. The CD94 and NKG2-A C-type lectins covalently assemble to form a natural killer cell inhibitory receptor for HLA class I molecules. Eur J Immunol 27:563-567, 1997
9. Chang, C., Rodriguez, A., Carretero, M, Lopez-Botet, M., Phillips, J.H. and Lanier, L. Molecular characterization of human CD94: a type II membrane glycoprotein related to the C type lectin superfamily. Eur J Immunol 25: 2433-2437, 1995
10. Church, G.M. and Gilbert, W., Genomic sequencing. Proc Natl Acad Sci USA 81: 1991-1995, 1984
11. Colonna, M. and Samaridis, J. Cloning of immunoglobulin-superfamily members associated with HLA-C and HLA-B recognition by human natural killer cells Science 268: 405-408, 1995
12. D'Andrea, A., Chang, C., Franz-Bacon, K., McClanahan, T., Phillips, J.H., Lanier, L.L. Molecular cloning of NKB1. A natural killer cell receptor for HLA-B allotypes. J Immunol 155: 2306-2310, 1995
13. Dear, S. and Staden, R. A sequence assembly and editing program for efficient management of large projects. Nucleic Acids Res 19: 3907-3911, 1991
14. Dissen, E., Ryan, J.C., Seaman, W.E., and Fossum, S. An autosomal dominant locus, Nka, mapping to the Ly-49 region of a rat natural killer (NK) gene complex, controls NK cell lysis of allogeneic lymphocytes. J Exp Med 183: 2197-2207, 1996
15. Dissen, E., Berg, S.F., Westgaard, I.H., Fossum, S. Molecular characterization of a gene in the rat homologous to human CD94. Eur J Immunol 27: 2080-2086, 1997
16. Duchler, M., Offterdinger, M., Holzmuller, H., Lipp, J., Chu, C.-T., Ashauer, B., Bach, F.H., and Hofer, E. NKG2-C is a receptor on human natural killer cells that recognizes structures on K562 target cells. Eur Immunol 25: 2923-2931, 1995
17. Feinberg, A.P., and Vogelstein, B.A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal Biochem 132: 6-13, 1983
18. Francis, F., Zehetner, G., Hoglund, M., and Lehrach, H. Construction and preliminary analysis of the ICRF human P1 library. GATA 11: 148-157, 1994
19. Frech, B. and Peterhans, E. RT-PCR - background priming during reverse transcription. Nucleic Acids Res 22: 4342-4343, 1994
20. Hofer, E., Duchler, M., Fuad, S.A., Houchins, J.P., Yabe, T., Bach, F.H. Candidate natural killer cell receptors. Immunol Today 13: 429-430, 1992
21. Hoglund, P., Sundback, J., Olsson-Alheim, M.Y., Johansson M., Salcedo, M, Ohlen, C., Ljunggren, H.G., Sentman, C.L., Karre, K. Host MHC class I gene control of NK-cell specificity in the mouse. Immunol Rev. 155: 11-28, 1997
22. Houchins, J. P., Yabe, T., McSherry, C., and Bach, F. H. DNA sequence analysis of NKG2A family of related cDNA clones encoding type II integral membrane proteins on human natural killer cells. J Exp Med 173: 1017-1020, 1991
23. Houchins, J.P., Lanier, L.L., Niemi, E.C., Phillips, J.H., and Ryan, J.C. Natural killer cell cytolytic activity is inhibited by NKG2-A and activated by NKG2-C. J Immunol 158: 3603-3609, 1997
24. Ioannou, P.A., Anemiya, C.T., Garnes, J., Kroisel, P.M., Shizuya, H., Chen, C., Batzer, M.A., and DeJong, P.J. A new bacteriophage P1-derived vector for the propagation of large human DNA fragments. Nat Genet 6: 84-89, 1994
25. Kawasaki, E.S. Amplification of RNA. In PCR Protocols: A Guide to Methods and Applications, pp. 21-27, Academic Press, New York, 1990
26. Lanier, L.L. Chang, C., and Phillips, J.H. Human NKR-P1 A: a disulphide linked homodimer of the C-type lectin superfamily expressed by a subset of NK and T lymphocytes. J Immunol 153: 2417-2428, 1994
27. Lanier. L.L., Corliss, B.C., Wu, J., Leong, C., and Phillips, J.H. Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells. Nature 391: 703-707, 1998
28. Lazetic, S., Chang, C., Houchins, J.P., Lanier, L., and Phillips, J.H. Human natural killer cell receptors involved in MHC class I recognition are disulphide-linked heterodimers of CD94 and NKG2 subunits. J Immunol 157: 4741-4745, 1996
29. Lehrach, H., Drmanac, R., Hoheisel, J., Larinm Z., Lennon, G., Monaco, A.P., Nizetic, D., Zehetner, G., and Poustka, A. In K. E. Davies and S. M. Tilghman (eds.): Genome Analysis, Vol I. Genetic and Physical Mapping, pp 39-81. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N. Y. 1990
30. Makalowski, W., Mitchell, G.A., and Labuda, D. Alu sequences in the coding regions of mRNA: a source of protein variability. TIGS 10: 188-193, 1994
31. Moretta, A., Biassoni, R., Bottino, C., Pende, D., Vitale, M., Poggi, A., Mingari, M.C., and Moretta L. Major histocompatibility complex class I-specific receptors on human natural killer and T lymphocytes. Immunol Rev 155: 105-117, 1997
32. Pende, D., Biassoni, R., Cantoni, C., Verdiani, S., Falco, M., di Donato, C., Accame, L., Bottino, C., Moretta, A., and Moretta L. The natural killer cell receptor specific for HLA-A allotypes: a novel member of the p58/p70 family of inhibitory receptors that is characterized by three immunoglobulin-like domains and is expressed as a 140-kD disulphide-linked dimer. J Exp Med 184: 505-518, 1996
33. Plougastel, B., Jones, T., and Trowsdale, J. Genomic structure, chromosome location, and alternative splicing of the human NKG2A gene. Immunogenetics 44: 286-291, 1996
34. Plougastel, B., and Trowsdale, J. Cloning of NKG2-F, a new member of the NKG2 family of human natural killer cell receptor genes Eur J Immunol 27: 2835-2839, 1997
35. Raulet, D.H. and Held, W. Natural killer cell receptors: the offs and ons of NK cell recognition. Cell 82: 697-700, 1995
36. Renedo, M., Arce, F. Rodriguez, A., Carretero, M., Lanier, L.L., Lopez-Botet, M., and Fernandez-Ruiz, E. The human natural killer gene complex is located on chromosome 12p12-p13. Immunogenetics 46: 307-311, 1997
37. Robertson, M.J., Cochran, K.J., Cameron, C., Le, J.M., Tantravahi, R., and Ritz, J. Characterization of a cell line, NKL, derived from an aggressive human natural killer cell leukemia. Exp Hematol 24: 406-415, 1996
38. Sambrook, J., Fritsch, E.F., and Maniatis, T., Molecular Cloning: A Laboratory Manual, Cold Spring Harbor Laboratory, Cold Spring Harbor, 1989
39. Sharp, P.A. Speculations on RNA splicing Cell 23: 643-646, 1981
40. Trinchieri, G. Biology of natural killer cells Adv Immunol 47: 187-376, 1989
41. Vance, R.E., Tanamachi, D.M., Hanke, T., and Raulet, D.H. Cloning of a mouse homolog of CD94 extends the family of C-type lectins on murine natural killer cells. Eur J Immunol 27: 3236-3240, 1997
42. Waglmann, N., Biassoni, R., Cantoni, C., Verdiani, S., Malnati, M.S., Vitale, M., Bottino, C., Moretta, L., Moretta, A., and Long, E.O. Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains. Immunity 2: 439-449, 1995
43. Yokoyama, W.M., and Seaman, W.E. The Ly-49 and NKR-P1 gene families encoding lectin-like receptors on natural killer cells: the NK gene complex. Annut Rev Immunol 11: 613-635, 1993