New strategy for the construction of single-stranded plasmids with single mutagenic lesions

Chemical Research in Toxicology

Volumn 10, Issue 6, 1997, Pages 667-671

  Napolitano, Rita L ^a   Fuchs, Robert P P ^a  

^a ESBS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

DNA POLYMERASE; N (2 FLUORENYL)ACETAMIDE; OLIGONUCLEOTIDE; URACIL DNA GLYCOSYLTRANSFERASE;

ARTICLE; DNA ADDUCT; DNA REPLICATION; DNA REPLICATION ORIGIN; DNA SEQUENCE; ENZYME DEGRADATION; FRAMESHIFT MUTATION; MUTAGENESIS; PLASMID; SITE DIRECTED MUTAGENESIS;

DNA ADDUCTS; DNA, SINGLE-STRANDED; FRAMESHIFT MUTATION; GENETIC VECTORS; HUMANS; IN SITU HYBRIDIZATION; MUTAGENESIS, SITE-DIRECTED; OLIGONUCLEOTIDE PROBES; PLASMIDS;

EID: 0031004090     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx970018w     Document Type: Article

References (20)

1. Koffel-Schwartz, N., Maenhaut-Michel, G., and Fuchs, R. P. P. (1987) Specific Strand Loss in N-2-acetylaminofluorene-modified DNA. J. Mol. Biol. 193, 651-659.
2. Koffel-Schwartz, N., Coin, F., Veaute, X., and Fuchs, R. P. P. (1996) Cellular strategies for accommodating replication-hindering adducts in DNA: Control by the SOS response in E. coli. Proc. Natl. Acad. Sci. U.S.A. 93, 7805-7810.
3. Banerjee, S. K., Christensen, R. B., Lawrence, C. W., and LeClerc, J. E. (1988) Frequency and spectrum of mutations produced by a single cis-syn thymine-thymine cyclobutane dimer in a single-stranded vector. Proc. Natl. Acad. Sci. U.S.A. 85, 8141-8145.
4. LeClerc, J. E., Borden, A., and Lawrence, C. W. (1991) The thymine-thymine pyrimidine-pyrimidone(6-4) ultraviolet light photoproduct is highly mutagenic and specifically induces 3′ thymine-to-cytosine transitions in Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 88, 9685-9689.
5. Koehl, P., Burnouf, D., and Fuchs, R. P. P. (1989) Construction of plasmids containing a unique acetylaminofluorene adduct located within a mutation hot spot. J. Mol. Biol. 207, 355-364.
6. Lambert, I. B., Napolitano, R. L., and Fuchs, R. P. P. (1992) Carcinogen-induced frameshift mutagenesis in repetitive sequences. Proc. Natl. Acad. Sci. U.S.A. 89, 1310-1314.
7. Sagher, D., and Strauss, B. (1983) Insertion of nucleotides opposite Apurinic/Apyrimidinic sites in DNA during in vitro synthesis: uniqueness of adenine nucleotides. Biochemistry 22, 4518-4526.
8. Kunkel, T. A. (1985) Rapid and efficient site-specific mutagenesis without phenotypic selection. Proc. Natl. Acad. Sci. U.S.A. 82, 488-492.
9. Koffel-Schwartz, N., Verdier, J. M., Bichara, M., Freund, A. M., Daune, M. P., and Fuchs, R. P. P. (1984) Carcinogen induced mutation spectrum in wild type, uvrA and umuC strains in E. coli: strain specificity and mutation prone sequences. J. Mol. Biol. 177, 33-51.
10. Veaute, X., and Fuchs, R. P. P. (1993) Greater susceptibility to mutations in lagging strand of DNA replication in Escherichia coli than in leading strand. Science 261, 598-600.
11. Burnouf, D., Koehl, P., and Fuchs, R. P. P. (1989) Single adduct mutagenesis: strong effect of the position of a single acetylaminofluorene adduct within a mutation hot spot. Proc. Natl. Acad. Sci. U.S.A. 86, 4147-4151.
12. Napolitano, R. L., Lambert, I. B., and Fuchs, R. P. P. (1994) DNA sequence determinants of carcinogen-induced frameshift mutagenesis. Biochemistry 33, 1311-1315.
13. Fuchs, R. P. P., Schwartz, N., and Daune, M. P. (1981) Hot Spots of frameshift mutations induced by the ultimate carcinogen N-Acetoxy-N-2-acetylaminofluorene. Nature 294, 657-659.
14. Belguise-Valladier, P., Maki, H., Sekiguchi, M., and Fuchs, R. P. P. (1994) Effect of single DNA lesions on in vitro replication with DNA polymeraseIII holoenzyme: comparison with other polymerases. J. Mol. Biol. 236, 151-164.
15. Belguise-Valladier, P., and Fuchs, R. P. P. (1995) N-2-Aminofluorene and N-2-acetylaminofluorene adducts: the local sequence context of an adduct and its chemical structure determine its replication properties. J. Mol. Biol. 249, 903-913.
16. Lindsley, J. E., and Fuchs, R. P. P. (1994) Use of single-turnover kinetics to study adduct bypass by T7 DNA polymerase. Biochemistry 33, 764-772.
17. Napolitano, R. L., Lambert, I. B., and Fuchs, R. P. P. (1997) SOS factors involved in error free versus error prone translesion synthesis at frameshift mutation hot spots. Proc. Natl. Acad. Sci. U.S.A., in press.
18. Zypursky, S. L., and Marians, K. J. (1980) Identification of two E. coli factor Y effector sites near the origins of replication of the plasmids ColE1 and pBR322. Proc. Natl. Acad. Sci. U.S.A. 77, 6521-6525.
19. Zypursky, S. L., and Marians, K. J. (1981) E. coli factor Y sites of plasmid pBR322 can function as origins of DNA replication. Proc. Natl. Acad. Sci. U.S.A. 78, 6111-6115.
20. Kornberg, A., and Baker, T. (1991) DNA Replication, 2nd ed., W. H. Freeman, New York.