Erythrocyte survival is promoted by plasma and suppressed by a Bak-derived BH3 peptide that interacts with membrane-associated Bcl-XL

Blood

Volumn 99, Issue 9, 2002, Pages 3439-3448

  Walsh, Melanie ^a,b   Lutz, Robert J ^a,b   Cotter, Thomas G ^a,b   O'Connor, Rosemary ^a,b  

^a UNIVERSITY COLLEGE CORK   (Ireland)

^b IMMUNOGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; BH3 PROTEIN; CASPASE INHIBITOR; PHOSPHATIDYLSERINE; PROTEIN BAK; PROTEIN BCL X; UNCLASSIFIED DRUG;

ARTICLE; CALCIUM CELL LEVEL; CELL CULTURE; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; ERYTHROCYTE LIFESPAN; HUMAN; HUMAN CELL; PLASMA; PRIORITY JOURNAL;

EID: 0036565880     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.V99.9.3439     Document Type: Article

References (47)

1. Survival factors and apoptosis
2. A matter of life and cell death
3. Molecular mechanisms of programmed cell death
4. Serine/threonine protein kinases and apoptosis
5. The proto-oncogene Bcl-2 and its role in regulating apoptosis
6. Double identity for proteins of the Bcl-2 family
7. The biochemistry of apoptosis
8. A conserved domain in Bak, distinct from BH1 and BH2, mediates cell death and protein binding functions
9. Bcl-xL regulates apoptosis by heterodimerization-dependent and-independent mechanisms
10. In vivo recognition and clearance of red blood cells containing phosphatidylserine in their plasma membranes
11. Exposure of phosphatidylserine in the outer leaflet of human red blood cells: Relationship to cell density, cell age, and clearance by mononuclear cells
12. Corpse clearance defines the meaning of cell death
13. GATA-1 and erythropoietin cooperate to promote erythroid cell survival by regulating bcl-xL expression
14. Insulin-like growth factor I receptors on blood cells: Their relationship to circulating total and "free" IGF-I, IGF-BP-1, IGf-BP3, and insulin levels in healthy subjects
15. Erythropoietin can promote erythroid progenitor survival by repressing apoptosis through Bcl-XL and Bcl-2
16. Erythropoietin can induce the expression of bcl-x(L) through Stat5 in erythropoietin-dependent progenitor cell lines
17. Defective Ca(2+)-induced microvesiculation and deficient expression of procoagulant activity in erythrocytes from a patient with a bleeding disorder: A study of the red blood cells of Scott syndrome
18. Detection of altered membrane phospholipid asymmetry in subpopulations of human red blood cells using fluorescently labeled annexin V
19. Effect of cell ageing on Ca2+ influx into human red cells
20. Programmed cell death and the control of cell survival
21. Fas ligand, Bcl-2, granulocyte colony-stimulating factor, and p38 mitogen-activated protein kinase: Regulators of distinct cell death and survival pathways in granulocytes
22. Interleukin-9 enhances interleukin-5 receptor expression, differentiation, and survival of human eosinophils
23. The mechanism of apoptosis in human platelets during storage
24. Constitutive death of platelets leading to scavenger receptor-mediated phagocytosis: A caspase-independent cell clearance program
25. Bak BH3 peptides antagonize Bcl-xL function and induce apoptosis through cytochrome c-independent activation of caspases
26. Short survival of phosphatidylserine-exposing red blood cells in murine sickle cell anemia
27. Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: Inhibition by overexpression of Bcl-2 and Abl
28. Mammalian cytochrome-c oxidase: Characterization of enzyme and immunological detection of subunits in tissue extracts and whole cells
29. Evidence from CDNA clones that the rat leukocyte-common antigen (T200) spans the lipid bilayer and contains a cytoplasmic domain of 80,000 Mr
30. Evidence of a role for SHP-1 in platelet activation by the collagen receptor glycoprotein VI
31. Structure of platelet glycoprotein IIIa: A common subunit for two different membrane receptors
32. Hematopoietic cell phosphatase associates with erythropoietin (Epo) receptor after Epo-induced receptor tyrosine phosphorylation: Identification of potential binding sites
33. The insulin-like growth factor-I receptor is regulated by CD28 and protects activated T cells from apoptosis
34. Apoptosis induced by erythroid differentiation of human leukemia cell lines is inhibited by Bcl-XL
35. The roles of Bcl-X(L) and apopain in the control of erythropoiesis by erythropoietin
36. Conditional deletion of the Bcl-x gene from erythroid cells results in hemolytic anemia and profound splenomegaly
37. X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death
38. BH3-only proteins that bind prosurvival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak
39. Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death
40. bcl-XL is the major bcl-x mRNA form expressed during murine development and its product localizes to mitochondria
41. Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria
42. The role of bcl-XL in CD40-mediated rescue from anti-mu-induced apoptosis in WEHI-231 B lymphoma cells
43. p28 Bap31, a Bcl-2/Bcl-XL- and procaspase-8-associated protein in the endoplasmic reticulum
44. Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC
45. Regulation of phosphatidylserine transbilayer redistribution by store-operated ca2+ entry: Role of actin cytoskeleton
46. Isolation of an erythrocyte membrane protein that mediates Ca2+-dependent transbilayer movement of phospholipid
47. Loss of membrane phospholipid asymmetry in platelets and red cells may be associated with calcium-induced shedding of plasma membrane and inhibition of aminophospholipid translocase