Interleukin-9 enhances interleukin-5 receptor expression, differentiation, and survival of human eosinophils

Blood

Volumn 96, Issue 6, 2000, Pages 2163-2171

  Gounni, A S ^a   Gregory, B ^a   Nutku, E ^a   Aris, F ^a   Latifa, K ^a   Minshall, E ^a   North, J ^a   Tavernier, J ^a   Levit, R ^a   Nicolaides, N ^a   Robinson, D ^a   Hamid, Q ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 5 RECEPTOR; INTERLEUKIN 9; INTERLEUKIN 9 RECEPTOR; MESSENGER RNA;

APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL FUNCTION; CELL MATURATION; CELL SURVIVAL; EOSINOPHILIA; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION;

EID: 0034665658     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v96.6.2163.h8002163_2163_2171     Document Type: Article

References (54)

1. Immunological aspects of allergic asthma
2. Leukocyte infiltration in allergic airway inflammation
3. Mechanisms of eosinophil recruitment
4. The immunobiology of eosinophils
5. Asthma and inflammation
6. Interleukin-5, eosinophils, and disease
7. Human interleukin-5 (IL-5) regulates production of eosinophils in human bone marrow cultures: Comparison and interaction with IL-1, IL-3, IL-6 and GM-CSF
8. The biology of the eosinophilic leukocyte
9. Functional and structural characterization of P40, a mouse glycoprotein with T-cell growth factor activity
10. Mast cell growth-enhancing activity (MEA) is structurally related and functionally identical to the novel mouse T celt growth factor P40/TCGFIII (interleukin 9)
11. + T cells, genomic organization, and comparison with the mouse gene
12. Differential regulation of IL-9 expression after infection with Leishmania major in susceptible and resistant mice
13. Interleukin-9 potentiates the interleukin-4 induced IgE and IgG1 release from murine B lymphocytes
14. High serum IgE concentrations: Association with HLA-DR and markers on chromosome 5q31 and chromosome 11q13
15. Genetic susceptibility to asthma-bronchial hyperresponsiveness coinherited with a major gene for atopy
16. Allelic association of gene markers on chromosomes 5q and 11q with atopy and bronchial hyperresponsiveness
17. Interleukin-9: A candidate gene for asthma
18. A genome-wide search for asthma susceptibility loci in ethnically diverse populations
19. Molecular organization of the cytokine gene cluster, involving the human IL-3, IL-4, IL-5, and GM-CSF genes, on human chromosome 5
20. Linkage analysis of IL-4 and other chromosome 5q31.1 markers and total serum immunoglobulin E concentrations
21. Interleukin-9 pathway in asthma: New therapeutic targets for allergic inflammatory disorders
22. Expression of interleukin-9 in the lungs of transgenic mice causes airway inflammation, mast cell hyperplasia, and bronchial hyperresponsiveness
23. Interleukin-9 promotes allergen induced eosinophilic inflammation and airway hyperresponsiveness in transgenic mice
24. Interleukin-9 induces chemokines expression in lung epithelial cells and baseline airway eosinophilia in transgenic mice
25. Functional and biochemical characterization of mouse P40/IL-9 receptors
26. Expression cloning of the murine and human interleukin-9 receptor cDNAs
27. Asthma and bronchial hyperresponsiveness linked to the XY long arm pseudoautosomal region
28. Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma [official statement of the American Thoracic Society, adopted by the Board Directors, November 1986]
29. An improved immunomagnetic procedure for the isolation of high purified human blood eosinophils
30. Molecular analysis of human interleukin-9 receptor transcripts in peripheral blood mononuclear cells: Identification of splice variant encoding for a non-functional cell surface receptor
31. Activation of CD4+ T cells, increased TH2-type cytokine mRNA expression, and eosinophil recruitment in bronchoalveolar lavage after allergen inhalation challenge in patients with atopic asthma
32. Morphological and biochemical characterisation and analysis of apoptosis
33. Platelet activating factor abrogates apoptosis induced by cross liking of the surface IgM receptor in human B lymphoblastoid cell line
34. Organization and chromosomal localization of the human interleukin 5 receptor α-chain gene
35. Graded increase probability of eosinophilic differentiation of HL-60 promyelocytic leukemia cells induced in culture under alkaline conditions
36. Interleukin-9 is a major anti-apopototic factor for thymic lymphomas
37. Differential activity of dexamethasone on IL-2-, IL-4, or IL-9-induced proliferation of murine factor-dependent T cell lines
38. Analysis of the survival of mature human eosinophils: Interleukin-5 prevents apoptosis in mature human eosinophils
39. Allergen induced increases in IL-5 receptor α subunit expression on bone marrow derived CD34+ cells from asthmatic subjects. A novel marker of progenitor cell commitment towards eosinophilic differentiation
40. Apoptosis in human eosinophils: Programmed cell death in the eosinophil leads to phagocytosis by macrophages and is modulated by IL-5
41. IL-5-dependent conversion of normodense human eosinophils to the hypodense phenotype uses 3T3 fibroblasts for enhanced viability, accelerated hypodensity, and sustained antibody-dependent cytotoxicity
42. Jak1 kinase forms complexes with interleukin-4 receptor and 4 PS/insulin receptor substrate1-like protein and is activated by interleukin-4 and interleukin-9 in T lymphocytes
43. Heterodimerization of the γc chain with the interleukin-9 receptor subunit leads to STAT activation and prevention of apoptosis
44. Interleukin-9 induces tyrosine phosphorylation of insulin receptor substrate-1 via JAK tyrosine kinases
45. Activation of Jak-3 but not Jak-1 is critical for IL-2 induced proliferation and Stat5 recruitment by a COOH-terminal region of the IL-2 receptor β-chain
46. Tyrosine phosphorylation and activation of JAK family tyrosine kinases by interleukin-9 in MO7E cells
47. Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: Involvement of STAT3 in anti-apoptosis
48. Characterization of a receptor for interleukin-5 on human eosinophils. Variable expression and induction by granulocyte macrophage colony stimulating factor
49. Interleukin-5 receptor alpha chain mRNA is down-regulated by transforming growth factor beta 1
50. Selective inhibition of IL-5 receptor alpha-chain gene transcription by IL-5, IL-3, and granulocyte-macrophage colony stimulating factor in human blood eosinophils
51. Interleukin-9 stimulates the proliferation of human myeloid leukemic cells
52. Membrane bound and soluble IL-5 receptor mRNA in the bronchial mucosa of atopic and non atopic asthmatics
53. +/IL-5Rα mRNA cells in the bronchial mucosa in asthma: Evidence for airway eosinophil progenitors