Expression of tumour necrosis factor-alpha (TNF-α) mRNA and protein in pathological thyroid tissue and carcinoma cell lines

Clinical and Experimental Immunology

Volumn 105, Issue 1, 1996, Pages 148-154

  Aust, G ^a   Heuer, M ^a   Laue, S ^a   Lehmann, I ^a   Hofmann, A ^a   Heldin, N E ^b   Scherbaum, W A ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b UPPSALA UNIVERSITY   (Sweden)

Author keywords

quantitative reverse transcriptase polymerase chain reaction; thyroid; tumour necrosis factor alpha

Indexed keywords

TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; DNA SYNTHESIS; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; GRAVES DISEASE; HASHIMOTO DISEASE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; MALE; PRIORITY JOURNAL; QUANTITATIVE DIAGNOSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; THYROID CARCINOMA; THYROID FUNCTION; TISSUE SPECIFICITY;

EID: 0030055347     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.1996.d01-726.x     Document Type: Article

References (40)

1. Deuss U, Buscema M, Schumacher H, Winkelmann W. In vitro effects of tumor nerosis factor-alpha on human thyroid follicular cells. Acta Endocrinol 1992; 127:220-5.
2. Pang XP, Yoshimura M, Hershman JM. Suppression of rat thyrotroph and thyroid cell function by tumor necrosis factor-alpha. Thyroid 1993; 3:325-30.
3. Weetman AP, Bright Thomas R, Freeman M. Regulation of interleukin-6 release by human thyrocytes. J Endocrinol 1990: 127:357-61.
4. Rasmussen AK, Kayser L, Feldt Rasmussen U, Bendtzen K. Influence of tumour necrosis factor-alpha, tumour necrosis factor-beta and interferon-gamma, separately and added together with interleukin-1 beta, on the function of cultured human thyroid cells. J Endocrinol 1994; 143:359-65.
5. 125I organification and thyroid hormone release by interleukin-1, tumor necrosis factor-alpha, and interferon-gamma in human thyrocytes in suspension culture. J Clin Endocrinol Metab 1990; 70:1735-43.
6. Weetman AP, Rees AJ. Synergistic effects of recombinant tumour necrosis factor and interferon-gamma on rat thyroid cell growth and ia antigen expression. Immunology 1988; 63:285-9.
7. Buscema M, Todd I, Deuss U et al. Influence of tumor necrosis factor-alpha on the modulation by interferon-gamma of HLA class II molecules in human thyroid cells and its effect on interferon-gamma binding. J Clin Endocrinol Metab 1989; 69:433-9.
8. Paschke R, Kist A, Janicke R, Eck T, Velu T, Usadel KH. Lack of intrathyroidal tumor necrosis factor alpha in Graves' disease. J Clin Endocrinol Metab 1993; 76:97-102.
9. Grubeck-Loebenstein B, Buchan G, Chantry D et al. Analysis of intrathyroidal cytokine production in thyroid autoimmune disease: thyroid follicular cells produce interleukin-1 alpha and interleukin-6. Clin Exp Immunol 1989; 77:324-30.
10. Zheng RQ, Abney ER, Chu CQ et al. Detection of in vivo production of tumour necrosis factor-alpha by human thyroid epithelial cells. Immunology 1992; 75:456-62.
11. Watson PF, Pickerill AP, Davies R, Weetman AP. Analysis of cytokine gene expression in Graves' disease and multinodular goiter. J Clin Endocrinol Metab 1994; 79:355-60.
12. Del Prete GF, Tiri A, de Carli M et al. High potential to tumor necrosis factor alpha (TNF-alpha) production of thyroid infiltrating T lymphocytes in Hashimoto's thyroiditis: a peculiar feature of destructive thyroid autoimmunity. Autoimmunity 1989; 4:267-76.
13. Davies TF. Co-cultures of human thyroid monolayer cultures of human thyroid monolayer cells and autologous T cells - impact of HLA class II antigen expression. J Clin Endocrinol Metab 1995; 61:418-23.
14. Mark J, Ekedahl C, Dahlenfors R, Westermark B. Cytogenetical observations in five human anaplastic thyroid carcinomas. Hereditas 1987; 107:163-74.
15. Heldin NE, Cvejic D, Smeds S, Westermark B. Coexpression of functionally active receptors for thyrotropin and platelet-derived growth factor in human thyroid carcinoma cells. Endocrinology 1991; 129:2187-93.
16. Platzer C, Ode-Hakim S, Reinke P, Docke WD, Ewert R, Volk HD. Quantitative PCR analysis of cytokine transcription patterns in peripheral mononuclear cells after anti-CD3 rejection therapy using two novel multispecific competitor fragments. Transplantation 1994; 58:264-8.
17. Heuer M, Aust G, Ode-Hakim S, Scherbaum WA. Different cytokine m RNA profiles in Graves' disease, Hashimoto's thyroiditis and non-autoimmune thyroid disorders determined by quantitative reverse transcriptase chain reaction (RT-PCR). Thyroid 1996; 6:97-106.
18. Aust G, Lehmann I, Laue S, Scherbaum WA. Activated and IFN-gamma producing thyroid-derived T cells are detected in Graves' disease, thyroid autonomy as well as in non-toxic multinodular goiter. Eur J Endocrinol 1996; (in press).
19. Saalbach A, Anderegg U, Schnabel E, Herrmann K, Haustein UF. Novel fibroblast-specific monoclonal antibodies: properties and specificities. J Invest Dermatol 1996; (in press).
20. Ewins DL, Barnett PS, Tomlinson RW, McGregor AM, Banga JP. Mapping epitope specificities of monoclonal antibodies to thyroid peroxidase using recombinant antigen preparations. Autoimmunity 1992; 11:141-9.
21. Ongphiphadhanakul B, Fang SL, Tang KT, Patwardhan NA, Braverman L. Tumor necrosis factor-alpha decreases thyrotropin-induced 5′-deiodinase activity in FRTL-5 thyroid cells. Eur J Endocrinol 1994; 130:502-7.
22. Grubeck-Loebenstein B, Buchan G, Chantry D, Turner M, Londei M, Feldmann M. Intrathyroidal cytokine production in thyroid disease. J Autoimmun 1989; 2 (Suppl.):171-6.
23. van der Gaag RD, Drexhage HA, Wiersinga WM et al. Further studies in thyroid growth-stimulating immunoglobulins in euthyroid nonendemic goiter. J Clin Endocrinol Metab 1985; 60:972-9.
24. Kraiem Z, Glaser B, Yigla M, Pauker J, Sadeh O, Sheinfeld M. Toxic multinodular goiter: a variant of autoimmune hyperthyroidism. J Clin Endocrinol Metab 1987; 65:659-64.
25. Grubeck-Loebenstein B, Derfler K, Kassal H et al. Immunological features of nonimmunogenic hyperthyroidism. J Clin Endocrinol Metab 1985; 60:150-5.
26. Sellschopp C, Derwahl M, Schaube H, Hamelmann H. Evidence of autoimmune pathogenesis in autonomous thyroid adenoma. Acta Endocrinol Suppl (Copenh) 1987; 281:355-7.
27. Corrales JJ, Orfao A, Miralles JM et al. Immunological features of sporadic multinodular goiter. Clin Invest 1993; 71:552-8.
28. Resetkova E, Morita T, Akasu F, Carayon P, Volpe R. In vitro effects of cytokines and human thyroglobulin on the induction of antibody-secreting cells in patients with autoimmune thyroid disease. Clin Invest Med 1993; 16:256-64.
29. Sung SS, Bjorndahl JM, Wang CY, Kao HT, Fu SM. Production of tumor necrosis factor/cachectin by human T cell lines and peripheral blood T lymphocytes stimulated by phorbol myristate acetate and anti-CD3 antibody. J Exp Med 1988; 167:937-53.
30. Steffen M, Ottmann OG, Moore MA. Simultaneous production of tumor necrosis factor-alpha and lymphotoxin by normal T cells after induction with IL-2 and anti-t3. J Immunol 1988; 140:2621-4.
31. Beutler B, Cerami A. The biology of cachectin/TNF-α primary-mediator of the host response. Annu Rev Immunol 1989; 7:625-55.
32. Sung SS, Jung LK, Walters JA, Chen W, Wang CY, Fu SM. Production of tumor necrosis factor/cachectin by human B cell lines and tonsillar B cells. J Exp Med 1988; 168:1539-51.
33. Chelly J, Concordet JP, Kaplan JC, Kahn A. Illegitimate transcription: transcription of any gene in any cell type. Proc Natl Acad Sci USA 1989; 86:2617-21.
34. Havell EA, Rogerson BJ. Endotoxin-induced tumor necrosis factor alpha synthesis in murine embryo fibroblasts. Infect Immun 1993; 61:1630-5.
35. Spriggs DR, Deutsch S, Kufe DW. Genomic structure, induction, and production of TNF-alpha. Immunol Ser 1992; 56:3-34.
36. Huleihel M, Douvdevani A, Segal S, Apte RN. Different regulatory levels are involved in the generation of hemopoietic cytokines (CSFs and IL-6) in fibroblasts stimulated by inflammatory products. Cytokine 1993; 5:47-56.
37. Havell EA, Sehgal PB. Tumor necrosis factor-independent IL-6 production during murine listeriosis. J Immunol 1991; 146:756-61.
38. Duncombe AS, Heslop HE, Turner M et al. Tumor necrosis factor mediates autocrine growth inhibition in a chronic leukemia. J Immunol 1989; 143:3828-34.
39. Mannel DN, Ruschoff J, Orosz P. The role of TNF in tumour growth and metastasis. Res Immunol 1993; 144:364-9.
40. Orosz P, Kruger A, Hubbe M, Ruschoff J, Von Hoegen P, Mannel DN. Promotion of experimental liver metastasis by tumor necrosis factor. Int J Cancer 1995; 60:867-71.