Neurotrauma/neurodegeneration and mitochondrial dysfunction

Progress in Brain Research

Volumn 137, Issue , 2002, Pages 171-176

  Frantseva, Marina ^a,b   Perez Velazquez, Jose Luis ^b   Tonkikh, Alexandre ^a   Adamchik, Yana ^a   Carlen, Peter L ^a  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BENZODIAZEPINE RECEPTOR; CALCIUM ION; CYCLOPHILIN; CYCLOSPORIN A; FREE RADICAL; MITOCHONDRIAL PROTEIN; TERT BUTYL HYDROPEROXIDE;

BRAIN HYPOXIA; BRAIN INJURY; BRAIN ISCHEMIA; BRAIN METABOLISM; BRAIN MITOCHONDRION; BRAIN SLICE; CALCIUM CELL LEVEL; CELL DAMAGE; CONFERENCE PAPER; DEPOLARIZATION; ENERGY METABOLISM; HUMAN; HYPOGLYCEMIA; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; NERVE CELL NECROSIS; NERVE DEGENERATION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL;

EID: 0036454380     PISSN: 00796123     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0079-6123(02)37015-8     Document Type: Conference Paper

References (47)

1. Adamchik, Y., Frantseva, M.V., Weisspapir, M., Carlen, P. and Perez Velazquez, J.L. (2000) Methods to induce primary and secondary traumatic damage in organotypic hippocampal slice cultures. Brain Res. Protoc., 5: 153-158.
2. Andreeva, L., Tanveer, A. and Crompton, M. (1995) Evidence for the involvement of a membrane-associated cyclosporin-A-binding protein in the calcium activated inner membrane pore of heart mitochondria. Eur. J. Biochem., 230(3): 1125-1132.
3. Braughler, J.M. and Hall, E.D. (1992) Central nervous system trauma and stroke. Free Radic. Biol. Med., 6: 289-301.
4. Chinopoulos, C., Tretter, L. and Adam-Vizi, V. (1999) Depolarization of in situ mitochondria due to hydrogen peroxide-induced oxidative stress in nerve terminals: Inhibition of αketoglutarate dehydrogenase. J. Neurochem., 73: 220-228.
5. Choi, D. (1990) Cerebral hypoxia: Some new approaches and unanswered questions. J. Neurosci., 10(8): 2493-2501.
6. Crompton, M. and Andreeva, L. (1993) On the involvement of a mitochondrial pore in reperfusion injury. Basic Res. Cardiol., 88(5): 513-523.
7. Crompton, M. and Costi, A. (1988) Kinetic evidence for a heart mitochondrial pore activated by calcium, inorganic phosphate and oxidative stress. Eur. J. Biochem., 178: 489-501.
8. Crompton, M., Costi, A. and Hayat, L. (1987) Evidence for the presence of a reversible calcium dependent pore activated by oxidative stress in heart mitochondria. Biochem. J., 245: 915- 918.
9. D'Ambrosio, R., Maris, D.O., Grady, M.S., Winn, H.R. and Janigro, D. (1999) Impaired K+ homeostasis and altered electrophysiological properties of post-traumatic hippocampal glia. J. Neurosci., 19: 8152-8162.
10. Dixon, C.E., Lyeth, B.G., Povlishock, J.T., Findling, R.L., Hamm, R.J., Marmarou, A., Young, H.F. and Hayes, R.L. (1987) A fluid percussion model of experimental brain injury in the rat. J. Neurosurg., 67: 110-119.
11. 2+ and prooxidants is associated with oxidation of protein thiols forming cross-linked protein aggregates. J. Biol. Chem., 265: 19955-19960.
12. Frantseva, M.V., Carlen, P.L. and Perez Velazquez, J.L. (1999a) Molecular mechanisms of free radical production and protective efficacies of antioxidants in in vitro ischaemia-reperfusion. Ann. N.Y. Acad. Sci., 893: 286-290.
13. Frantseva, M.V., Carlen, P.L. and El-Beheiry, H. (1999b) A submersion method to induce hypoxic damage in organotypic hippocampal cultures. J. Neurosci. Methods, 89: 25-31.
14. Frantseva, M.V., Kokarovtseva, L., Carlen, P.L., Naus, C.C.G. and Perez Velazquez, J.L. (2001) Role of specific gap junctions in spreading brain traumatic injury. J. Neurosci., submitted.
15. Joshi, I. and Andrew, R.D. (2001) Imaging anoxic depolarization during ischemia-like conditions in the mouse hemi-brain slice. J. Neurophysiol., 85: 414-424.
16. Kiedrowski, L. and Costa, E. (1995) Glutamate induced destabilization of intracellular calcium concentration homeostasis in cultured cerebellar granule cells: Role of mitochondria in calcium buffering. Mol. Pharmacol., 47: 140-147.
17. Kirk, K. and Strange, K. (1998) Functional properties and physiological roles of organic solute channels. Annu. Rev. Physiol., 60: 719-739.
18. Kristal, B.S. and Dubinsky, J.M. (1997) Mitochondrial permeability transition in the central nervous system: Induction by calcium cycling-dependent and independent pathways. J. Neurochem., 69(2): 524-538.
19. Matlib, M.A., Zhou, Z., Knight, S., Ahmen, S., Choi, K.M., Krause-Bauer, J., Phillips, R., Altschuld, R.A., Katsube, Y. and Sperekalis, N. (1998) Oxygen-bridged dinuclear ruthenium amine complex specifically inhibits calcium uptake into mitochondria in vitro and in single cardiac myocytes. J. Biol. Chem., 273: 1022-10231.
20. McEnery, M.W., Snowman, A.M., Trifiletti, R.R. and Snyder, S.H. (1992) Isolation of the mitochondrial benzodiazepine receptor: Association with the voltage dependent anion channel and the adenine nucleotide carrier. Proc. Natl. Acad. Sci. USA, 89: 3170-3174.
21. McEnery, M.W., Dawson, T.M., Verma, A., Gurley, D., Colombini, M. and Snyder, S.H. (1993) Mitochondrial voltage-dependent anion channel. J. Biol. Chem., 268(31): 23289-23296.
22. Miller, J.D. (1985) Head injury and brain ischemia: Implications for therapy. Br. J. Anaesth., 57: 120-129.
23. Nicolli, A, Basso, E., Petronilly, V., Wengers, R. and Bernardi, P. (1996) Interactions of cyclophilin with the mitochondrial inner membrane and regulation of the permeability transition pore, a cyclosporin A-sensitive channel. J. Biochem., 271(4): 2185-2192.
24. Nieminen, A.L., Saylor, A.K., Tesfai, S.A., Herman, B. and Lemasters, J.J. (1995) Contribution of the mitochondrial permeability transition to lethal injury after exposure of hepatocytes to t-butylhydroperoxide. Biochem. J., 307: 99-106.
25. Okonkwo, D.O. and Povlishock, J.T. (1999) An intrathecal bolus of Cyclosporin A before injury preserves mitochondrial integrity and attenuates axonal dysruption in traumatic brain injury. J. Cereb. Blood Flow Metab., 19: 443-451.
26. Pastorino, J.G., Simbula, G., Gilfor, E., Hoek, J.B. and Farber, J.L. (1994) Protoporphyrin IX, an endogenous ligand of the peripheral benzodiazepine receptor, potentiates induction of the mitochondrial permeability transition and the killing of cultured hepatocytes by rotenone. J. Biol. Chem., 269(49): 31041-31046.
27. Perez Velazquez, J.L., Frantseva, M.V. and Carlen, P.L. (1997) In vitro ischemia promotes glutamate-mediated free radical generation and intracellular calcium accumulation in hippocampal pyramidal neurones. J. Neurosci., 17(23): 9085-9094.
28. Perez Velazquez, J.L., Frantseva, M.V., Huzar, D., Guezurian, C. and Carlen, P.L. (1999) Mitochondrial porin, a novel target to prevent ischaemia-induced neurodegeneration? Ann. N.Y. Acad. Sci., 893: 369-372.
29. Perez Velazquez, J.L., Frantseva, M.V., Huzar, D. and Carlen, P.L. (2000) Porin required for ischemia-induced mitochondrial dysfunction and neuronal damage. Neuroscience, 97(2): 363-369.
30. Richter, C., Winterhalter, K.H., Baumhuter, S., Lötscher, H.R. and Moser, B. (1983) ADP-ribosylation in the membrane of rat liver mitochondria. Proc. Natl. Acad. Sci. USA, 80: 3188-3192.
31. Schinder, A.F., Olson, E., Spitzer, N.C. and Montal, M. (1996) Mitochondrial dysfunction is a primary event in glutamate neurotoxicity. J. Neurosci., 16(19): 6125-6133.
32. Shiga, Y., Onodera, H., Matsuo, Y. and Kogure, K. (1992) Cyclosporin A protects against ischemia-reperfusion injury in the brain. Brain Res., 595: 145-148.
33. Shimizu, S., Narita, M. and Tsujimoto, Y. (1999) Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC. Nature, 399: 483-487.
34. Stoppini, L., Buchs, L.-A. and Muller, D. (1991) A simple method for organotypic cultures of nervous tissue. J. Neurosci. Methods, 37: 173-182.
35. Stout, A.K., Raphael, H.M., Kanterewicz, B.I., Klann, E. and Reynolds, I.J. (1998) Glutamate-induced neuron death requires mitochondrial calcium uptake. Nat. Neurosci., 1: 366-373.
36. Sullivan, P.G., Thompson, M.B. and Scheff, S.W. (1999) Cyclosporin A attenuates acute mitochondrial dysfunction following traumatic brain injury. Exp. Neurol., 160: 226-234.
37. Szabo, I., Bathori, G., Tombola, F., Coppola, A., Schmehl, I., Brini, M., Ghazi, A., DePinto, V. and Zoratti, M. (1998) Double-stranded DNA can be translocated across a planar membrane containing purified mitochondrial porin. FASEB J., 12(6): 495-502.
38. Tanveer, A., Virji, S., Andreeva, L., Totty, N.F., Hsuan, J.J., Ward, J.M. and Crompton, M. (1996) Involvement of cyclophilin D in the activation of a mitochondrial pore by calcium and oxidant stress. Eur. J. Biochem., 238(1): 166-172.
39. Vagnozzi, R., Marmarou, A., Tavazzi, B., Signoretti, S., Di Pierro, D., Del Bolgia, F., Amorini, A.M., Fazzina, G., Sherkat, S. and Lazzarino, G. (1999) Changes of cerebral energy metabolism and lipid peroxidation in rats leading to mitochondrial dysfunction after diffuse brain injury. J. Neurotrauma, 16(10): 903-913.
40. Verweij, B.H., Muizelaar, J.P., Vinas, F.C., Peterson, P.L., Xiong, Y. and Lee, C.P. (1997) Mitochondrial dysfunction after experimental and human brain injury and its possible reversal with a selective N-type calcium channel antagonist (SNX-111). Neurol. Res., 19: 334-339.
41. Vink, R., Head, V.A., Rogers, P.J., McIntosh, T.K. and Faden, A.I. (1990) Mitochondrial metabolism following traumatic brain injury in rats. J. Neurotrauma, 7: 21-27.
42. Weis, M., Kass, G.E., Orrenius, S. and Moldeus, P. (1992) N-acetyl-p-benzoquinone imine induces calcium release from mitochondria by stimulating pyridine nucleotide hydrolysis. J. Biol. Chem., 267(2): 804-809.
43. White, R.J. and Reynolds, I.J. (1996) Mitochondrial depolarization in glutamate-stimulated neurons: An early signal specific to excitotoxin exposure. J. Neurosci., 16(18): 5688-5697.
44. Xiong, Y., Gu, Q., Peterson, P.L., Muizelaar, J.P. and Lee, C.P. (1997) Mitochondrial dysfunction and calcium perturbation induced by traumatic brain injury. J. Neurotrauma, 14: 23-34.
45. Xiong, Y., Peterson, P.L., Verweij, B.H., Vinas, F.C., Muizelaar, J.P. and Lee, C.P. (1998) Mitochondrial dysfunction after experimental traumatic brain injury: Combined efficacy of SNX-111 and U-101033E. J. Neurotrauma, 15: 531-544.
46. Xiong, Y., Gu, Q., Peterson, P.L. and Lee, C.P. (1999) Effect of N-acetylcysteine on mitochondrial function following traumatic brain injury in rats. J. Neurotrauma, 16: 1067-1082.
47. Zoratti, M. and Szabo, I. (1995) The mitochondrial permeability transition. Biochem. Biophys Acta, 1241: 139-176.