메뉴 건너뛰기




Volumn 80, Issue 11, 2002, Pages 696-702

Adiponectin: A link between excess adiposity and associated comorbidities?

Author keywords

Adiponectin; Atherosclerosis; Fat; Glucose; Insulin

Indexed keywords

ADIPONECTIN; ANTIDIABETIC AGENT; ANTIOBESITY AGENT; INSULIN; LEPTIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PIOGLITAZONE; POLYPEPTIDE; THIAZOLIDINE DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; PROTEIN; SIGNAL PEPTIDE;

EID: 0036432925     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00109-002-0378-7     Document Type: Review
Times cited : (336)

References (69)
  • 1
    • 0027369940 scopus 로고
    • Syndrome X
    • Ferrannini E (1990) Syndrome X. Horm Res 39 [Suppl 3]: 107-111
    • (1990) Horm Res , vol.39 , Issue.SUPPL. 3 , pp. 107-111
    • Ferrannini, E.1
  • 2
    • 0024160877 scopus 로고
    • Role of insulin resistance in human disease
    • Reaven GM (1988) Role of insulin resistance in human disease. Diabetes 37:1595-1607
    • (1988) Diabetes , vol.37 , pp. 1595-1607
    • Reaven, G.M.1
  • 3
    • 0024391834 scopus 로고
    • The deadly quartet. Upper-body obesity, glucose intolerance, hypertriglyceridaemia, and hypertension
    • Kaplan NM (1989) The deadly quartet. Upper-body obesity, glucose intolerance, hypertriglyceridaemia, and hypertension. Arch Intern Med 149:1514-1520
    • (1989) Arch Intern Med , vol.149 , pp. 1514-1520
    • Kaplan, N.M.1
  • 4
    • 0027092522 scopus 로고
    • Abdominal obesity and the metabolic syndrome
    • Björntorp P (1992) Abdominal obesity and the metabolic syndrome. Ann Med 24:465-468
    • (1992) Ann Med , vol.24 , pp. 465-468
    • Björntorp, P.1
  • 5
    • 0035051032 scopus 로고    scopus 로고
    • Clustering of metabolic abnormalities in obese individuals: The role of genetic factors
    • Ukkola O, Bouchard C (2001) Clustering of metabolic abnormalities in obese individuals: The role of genetic factors. Ann Med 33:79-90
    • (2001) Ann Med , vol.33 , pp. 79-90
    • Ukkola, O.1    Bouchard, C.2
  • 7
    • 50549202600 scopus 로고
    • The glucose-fatty acid cycle. Its role in insulin sensitivity and the metabolic disturbances in diabetes mellitus
    • Randle PJ, Garland PB, Hales CN, Newsholme EA (1963) The glucose-fatty acid cycle. Its role in insulin sensitivity and the metabolic disturbances in diabetes mellitus. Lancet 1:785-789
    • (1963) Lancet , vol.1 , pp. 785-789
    • Randle, P.J.1    Garland, P.B.2    Hales, C.N.3    Newsholme, E.A.4
  • 8
    • 0032191009 scopus 로고    scopus 로고
    • Insulin resistance in obesity: Metabolic mechanisms and measurement methods
    • Belfiore F, Iannello S (1998) Insulin resistance in obesity: Metabolic mechanisms and measurement methods. Mol Genet Metab 65:121-128
    • (1998) Mol Genet Metab , vol.65 , pp. 121-128
    • Belfiore, F.1    Iannello, S.2
  • 9
    • 0025294346 scopus 로고
    • Associations between regional body fat distribution, fasting plasma free fatty acid levels and glucose tolerance in premenopausal women
    • Pouliot MC, Despres JP, Nadeau A, Tremblay A, Moorjani S, Lupien PJ, Theriault G, Bouchard C (1990) Associations between regional body fat distribution, fasting plasma free fatty acid levels and glucose tolerance in premenopausal women. Int J Obes 14:293-302
    • (1990) Int J Obes , vol.14 , pp. 293-302
    • Pouliot, M.C.1    Despres, J.P.2    Nadeau, A.3    Tremblay, A.4    Moorjani, S.5    Lupien, P.J.6    Theriault, G.7    Bouchard, C.8
  • 10
    • 0034033372 scopus 로고    scopus 로고
    • Visceral fat and insulin resistance - Causative or correlative?
    • Frayn KN (2000) Visceral fat and insulin resistance - Causative or correlative? Br J Nutr 83: S71-S77
    • (2000) Br J Nutr , vol.83
    • Frayn, K.N.1
  • 11
    • 0030765908 scopus 로고    scopus 로고
    • Subcutaneous abdominal fat and thigh muscle composition predict insulin sensitivity independently of visceral fat
    • Goodpaster BH, Thaete FL, Simoneau JA, Kelley DE (1997) Subcutaneous abdominal fat and thigh muscle composition predict insulin sensitivity independently of visceral fat. Diabetes 46:1579-1585
    • (1997) Diabetes , vol.46 , pp. 1579-1585
    • Goodpaster, B.H.1    Thaete, F.L.2    Simoneau, J.A.3    Kelley, D.E.4
  • 12
  • 13
    • 0033006868 scopus 로고    scopus 로고
    • Relationship of visceral adipose tissue to metabolic risk factors for coronary heart disease: Is there a contribution of subcutaneous fat cell hypertrophy?
    • Imbeault P, Lemieux S, Prud'homme D, Tremblay A, Nadeau A, Despres JP, Mauriege P (1999) Relationship of visceral adipose tissue to metabolic risk factors for coronary heart disease: Is there a contribution of subcutaneous fat cell hypertrophy? Metabolism 48:355-362
    • (1999) Metabolism , vol.48 , pp. 355-362
    • Imbeault, P.1    Lemieux, S.2    Prud'homme, D.3    Tremblay, A.4    Nadeau, A.5    Despres, J.P.6    Mauriege, P.7
  • 16
    • 0029836585 scopus 로고    scopus 로고
    • Isolation and characterization of GBP28, a novel gelatin-binding protein purified from human plasma
    • Nakano Y, Tobe T, Choi-Miura N-H, Mazda T, Tomita M (1996) Isolation and characterization of GBP28, a novel gelatin-binding protein purified from human plasma. J Biochem 120:803-812
    • (1996) J Biochem , vol.120 , pp. 803-812
    • Nakano, Y.1    Tobe, T.2    Choi-Miura, N.-H.3    Mazda, T.4    Tomita, M.5
  • 18
    • 0029980285 scopus 로고    scopus 로고
    • cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (AdiposeMost Abundant Gene Transcript 1)
    • Maeda K, Okubo K, Shimomura I, Funahashi T, Matsuzawa Y, Matsubara K (1996) cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (AdiposeMost Abundant Gene Transcript 1). Biochem Biophys Res Commun 221:286-289
    • (1996) Biochem Biophys Res Commun , vol.221 , pp. 286-289
    • Maeda, K.1    Okubo, K.2    Shimomura, I.3    Funahashi, T.4    Matsuzawa, Y.5    Matsubara, K.6
  • 20
    • 17544382289 scopus 로고    scopus 로고
    • AdipoQ is a novel adipose-specific gene dysregulated in obesity
    • Hu E, Liang P, Spiegelman BM (1996) AdipoQ is a novel adipose-specific gene dysregulated in obesity. J Biol Chem 271:10697-10703
    • (1996) J Biol Chem , vol.271 , pp. 10697-10703
    • Hu, E.1    Liang, P.2    Spiegelman, B.M.3
  • 21
    • 0029836585 scopus 로고    scopus 로고
    • Isolation and characterization of GBP28, a novel gelatin-binding protein purified from human plasma
    • Nakano Y, Tobe T, Choi-Miura NH, Mazda T, Tomita M (1996) Isolation and characterization of GBP28, a novel gelatin-binding protein purified from human plasma. J Biochem (Tokyo) 120:803-812
    • (1996) J Biochem (Tokyo) , vol.120 , pp. 803-812
    • Nakano, Y.1    Tobe, T.2    Choi-Miura, N.H.3    Mazda, T.4    Tomita, M.5
  • 22
    • 0037205414 scopus 로고    scopus 로고
    • Hydroxylation and glycosylation of the four conserved lysine residues in the collagenous domain of adiponectin. Potential role in the modulation of its insulin-sensitizing activity
    • Wang Y, Xu A, Knight C, Xu LY, Cooper GJ (2002) Hydroxylation and glycosylation of the four conserved lysine residues in the collagenous domain of adiponectin. Potential role in the modulation of its insulin-sensitizing activity. J Biol Chem 277:19521-19529
    • (2002) J Biol Chem , vol.277 , pp. 19521-19529
    • Wang, Y.1    Xu, A.2    Knight, C.3    Xu, L.Y.4    Cooper, G.J.5
  • 23
    • 0028787490 scopus 로고
    • A novel serum protein similar to C1q, produced exclusively in adipocytes
    • Scherer PE, Williams S, Fogliano M, Baldini G, Lodish HF (1995) A novel serum protein similar to C1q, produced exclusively in adipocytes. J Biol Chem 270:26746-26749
    • (1995) J Biol Chem , vol.270 , pp. 26746-26749
    • Scherer, P.E.1    Williams, S.2    Fogliano, M.3    Baldini, G.4    Lodish, H.F.5
  • 24
    • 0035039227 scopus 로고    scopus 로고
    • Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys
    • Hotta K, Funahashi T, Bodkin NL, Ortmeyer HK, Arita Y, Hansen BC, Matsuzawa Y (2001) Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys. Diabetes 50:1126-1133
    • (2001) Diabetes , vol.50 , pp. 1126-1133
    • Hotta, K.1    Funahashi, T.2    Bodkin, N.L.3    Ortmeyer, H.K.4    Arita, Y.5    Hansen, B.C.6    Matsuzawa, Y.7
  • 25
    • 0032510463 scopus 로고    scopus 로고
    • The crystal structure of a complement-1q family protein suggests an evolutionary link to tumor necrosis factor
    • Shapiro L, Scherer PE (1998) The crystal structure of a complement-1q family protein suggests an evolutionary link to tumor necrosis factor. Curr Biol 8:335-338
    • (1998) Curr Biol , vol.8 , pp. 335-338
    • Shapiro, L.1    Scherer, P.E.2
  • 26
    • 0032925340 scopus 로고    scopus 로고
    • Mechanisms of TNF-α-induced insulin resistance
    • Hotamisligil GS (1999) Mechanisms of TNF-α-induced insulin resistance. Exp Clin Endocrinol Diabetes 107:119-125
    • (1999) Exp Clin Endocrinol Diabetes , vol.107 , pp. 119-125
    • Hotamisligil, G.S.1
  • 27
    • 0036134187 scopus 로고    scopus 로고
    • Resistin and obesity-associated insulin resistance
    • Steppan CM, Lazar MA (2002) Resistin and obesity-associated insulin resistance. Trends Endocrinol Metab 13:18-23
    • (2002) Trends Endocrinol Metab , vol.13 , pp. 18-23
    • Steppan, C.M.1    Lazar, M.A.2
  • 33
    • 0035955453 scopus 로고    scopus 로고
    • Adiponectin gene expression is inhibited by beta-adrenergic stimulation via protein kinase A in 3T3-L1 adipocytes
    • Fasshauer M, Klein J, Neumann S, Eszlinger M, Paschke R (2001) Adiponectin gene expression is inhibited by beta-adrenergic stimulation via protein kinase A in 3T3-L1 adipocytes. FEBS Lett 507:142-146
    • (2001) FEBS Lett , vol.507 , pp. 142-146
    • Fasshauer, M.1    Klein, J.2    Neumann, S.3    Eszlinger, M.4    Paschke, R.5
  • 37
    • 0030914608 scopus 로고    scopus 로고
    • Endocrine abnormalities in obesity
    • Björntorp P (1997) Endocrine abnormalities in obesity. Diabetes Rev 5:52-68
    • (1997) Diabetes Rev , vol.5 , pp. 52-68
    • Björntorp, P.1
  • 38
    • 0033305213 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors: Nuclear control of metabolism
    • Desvergne B, Wahli W (1999) Peroxisome proliferator-activated receptors: Nuclear control of metabolism. Endrocr Rev 20:649-688
    • (1999) Endrocr Rev , vol.20 , pp. 649-688
    • Desvergne, B.1    Wahli, W.2
  • 43
    • 0025347389 scopus 로고
    • Muscle fibre type and aetiology of obesity
    • Wade AJ, Marbut MM, Round JM. Muscle fibre type and aetiology of obesity (1990) Lancet 335:805-808
    • (1990) Lancet , vol.335 , pp. 805-808
    • Wade, A.J.1    Marbut, M.M.2    Round, J.M.3
  • 44
    • 0035852760 scopus 로고    scopus 로고
    • Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice
    • Fruebis J, Tsao T-S, Javorschi S, Ebbets-Reed D, Erickson MR, Yen FT, Bihain BE, Lodish HF (2001) Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice. Proc Natl Acad Sci USA 98:2005-2010
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 2005-2010
    • Fruebis, J.1    Tsao, T.-S.2    Javorschi, S.3    Ebbets-Reed, D.4    Erickson, M.R.5    Yen, F.T.6    Bihain, B.E.7    Lodish, H.F.8
  • 45
    • 0035663963 scopus 로고    scopus 로고
    • Endogenous glucose production is inhibited by the adipose-derived protein Acrp30
    • Combs TP, Berg AH, Obici S, Scherer PE, Rossetti L (2001) Endogenous glucose production is inhibited by the adipose-derived protein Acrp30. J Clin Invest 108:1875-1881
    • (2001) J Clin Invest , vol.108 , pp. 1875-1881
    • Combs, T.P.1    Berg, A.H.2    Obici, S.3    Scherer, P.E.4    Rossetti, L.5
  • 46
    • 0034881391 scopus 로고    scopus 로고
    • The adipocyte-secreted protein Acrp30 enhances hepatic insulin action
    • Berg AH, Combs TP, Du X, Brownlee M, Scherer PE (2001) The adipocyte-secreted protein Acrp30 enhances hepatic insulin action. Nat Med 7:947-953
    • (2001) Nat Med , vol.7 , pp. 947-953
    • Berg, A.H.1    Combs, T.P.2    Du, X.3    Brownlee, M.4    Scherer, P.E.5
  • 51
    • 0037022910 scopus 로고    scopus 로고
    • Inflammation and atherosclerosis
    • Libby P, Ridker PM, Maseri A (2002) Inflammation and atherosclerosis. Circulation 105:1135-1143
    • (2002) Circulation , vol.105 , pp. 1135-1143
    • Libby, P.1    Ridker, P.M.2    Maseri, A.3
  • 52
    • 0034284038 scopus 로고    scopus 로고
    • Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages
    • Yokota T, Oritani K, Takahashi I, Ishikawa J, Matsuyama A, Ouchi N, Kihara S, Funahashi T, Tenner AJ, Tomiyama Y, Matsuzawa Y (2000) Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages. Blood 96:1723-1732
    • (2000) Blood , vol.96 , pp. 1723-1732
    • Yokota, T.1    Oritani, K.2    Takahashi, I.3    Ishikawa, J.4    Matsuyama, A.5    Ouchi, N.6    Kihara, S.7    Funahashi, T.8    Tenner, A.J.9    Tomiyama, Y.10    Matsuzawa, Y.11
  • 53
    • 0032779351 scopus 로고    scopus 로고
    • Molecular mechanism of metabolic syndrome X: Contribution of adipo-cytokines adipocyte-derived bioactive substances
    • Matsuzawa Y, Funahashi T, Nakamura T (1999) Molecular mechanism of metabolic syndrome X: Contribution of adipo-cytokines adipocyte-derived bioactive substances. Ann N Y Acad Sci 892:146-154
    • (1999) Ann N Y Acad Sci , vol.892 , pp. 146-154
    • Matsuzawa, Y.1    Funahashi, T.2    Nakamura, T.3
  • 56
    • 0033652271 scopus 로고    scopus 로고
    • Genomewide search for type 2 diabetes-susceptibility genes in French whites: Evidence for a novel susceptibility locus for early-onset diabetes on chromosome 3q27-qter and independent replication of a type 2-diabetes locus on chromosome 1q21-q24
    • Vionnet N, Hani El-H, Dupont S, Gallina S, Francke S, Dotte S, De Matos F, Durand E, Lepretre F, Lecoeur C, Gallina P, Zekiri L, Dina C, Froguel P 2000 Genomewide search for type 2 diabetes-susceptibility genes in French whites: evidence for a novel susceptibility locus for early-onset diabetes on chromosome 3q27-qter and independent replication of a type 2-diabetes locus on chromosome 1q21-q24. Am J Hum Genet 67:1470-1480
    • (2000) Am J Hum Genet , vol.67 , pp. 1470-1480
    • Vionnet, N.1    Hani, El.-H.2    Dupont, S.3    Gallina, S.4    Francke, S.5    Dotte, S.6    De Matos, F.7    Durand, E.8    Lepretre, F.9    Lecoeur, C.10    Gallina, P.11    Zekiri, L.12    Dina, C.13    Froguel, P.14
  • 61
    • 0036307162 scopus 로고    scopus 로고
    • A haplotype at the adiponectin locus is associated with obesity and other features of the insulin resistance syndrome
    • Menzaghi C, Ercolino T, Di Paola R, Berg AH, Warram JH, Scherer PE, Trischitta V, Doria A (2002) A haplotype at the adiponectin locus is associated with obesity and other features of the insulin resistance syndrome. Diabetes 51:2306-2312
    • (2002) Diabetes , vol.51 , pp. 2306-2312
    • Menzaghi, C.1    Ercolino, T.2    Di Paola, R.3    Berg, A.H.4    Warram, J.H.5    Scherer, P.E.6    Trischitta, V.7    Doria, A.8
  • 62
    • 0036091918 scopus 로고    scopus 로고
    • Association of the T-G polymorphism in adiponectin (exon 2) with obesity and insulin sensitivity: Interaction with family history of type 2 diabetes
    • Stumvoll M, Tschritter O, Fritsche A, Staiger H, Renn W, Weisser M, Machicao F, Haring H (2002) Association of the T-G polymorphism in adiponectin (exon 2) with obesity and insulin sensitivity: Interaction with family history of type 2 diabetes. Diabetes 51:37-41
    • (2002) Diabetes , vol.51 , pp. 37-41
    • Stumvoll, M.1    Tschritter, O.2    Fritsche, A.3    Staiger, H.4    Renn, W.5    Weisser, M.6    Machicao, F.7    Haring, H.8
  • 66
    • 0027983920 scopus 로고
    • Improvement in glucose tolerance and insulin resistance in obese subjects treated with troglitazone
    • Nolan JJ, Ludvik B, Beerdsen P, Joyce M, Olefsky J (1994) Improvement in glucose tolerance and insulin resistance in obese subjects treated with troglitazone. N Engl J Med 331: 1188-1193
    • (1994) N Engl J Med , vol.331 , pp. 1188-1193
    • Nolan, J.J.1    Ludvik, B.2    Beerdsen, P.3    Joyce, M.4    Olefsky, J.5
  • 68
    • 0036481709 scopus 로고    scopus 로고
    • Synthetic peroxisome proliferator-activated receptor-gamma agonist, rosiglitazone, increases plasma levels of adiponectin in type 2 diabetic patients
    • Yang WS, Jeng CY, Wu TJ, Tanaka S, Funahashi T, Matsuzawa Y, Wang JP, Chen CL, Tai TY, Chuang LM (2002) Synthetic peroxisome proliferator-activated receptor-gamma agonist, rosiglitazone, increases plasma levels of adiponectin in type 2 diabetic patients. Diabetes Care 25:376-380
    • (2002) Diabetes Care , vol.25 , pp. 376-380
    • Yang, W.S.1    Jeng, C.Y.2    Wu, T.J.3    Tanaka, S.4    Funahashi, T.5    Matsuzawa, Y.6    Wang, J.P.7    Chen, C.L.8    Tai, T.Y.9    Chuang, L.M.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.