Neuropathology of synthetic β-amyloid peptide analogs in vivo

Brain Research

Volumn 715, Issue 1-2, 1996, Pages 44-50

  Chen, Shiouh Yi ^b   Harding, Joseph W ^a   Barnes, Charles D ^a  

^a WASHINGTON STATE UNIVERSITY   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

choline acetyltransferase; glutamate; locus coeruleus; medical septum; tyrosine hydroxylase; (25 35)

Indexed keywords

AMYLOID BETA PROTEIN; CHOLINE ACETYLTRANSFERASE; GLUTAMIC ACID; TYROSINE 3 MONOOXYGENASE;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; LOCUS CERULEUS; MALE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; SEPTUM NUCLEUS;

EID: 0029923901     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(96)84503-3     Document Type: Article

References (20)

1. Barrow, C.J. and Zagorski, M.G., Solution structures of β peptide and its constituent fragments: relation to amyloid deposition, Science, 253 (1991) 179-182.
2. Burdick, D., Soreghan, B., Kwon, M., Kosmoski, J., Knauer, M., Henschen, A., Yates, J., Cotman, C. and Glabe, C., Assembly and aggregation properties of synthetic Alzheimer's A4/β amyloid peptide analogs. J. Biol. Chem., 267 (1992) 546-554.
3. Chen, S.-Y., Reddy, V.K. and Barnes, C.D., Reduction of tyrosine hydroxylase and glutamate in the locus coeruleus as well as choline acetyltransferase in the medial septum following the administration of β-amyloid peptide (25-35) into the hippocampus, submitted.
4. Fung, S.J., Reddy, V.K., Liu, R.-H., Wang, Z. and Barnes, C.D., Existence of glutamate in noradrenergic locus coeruleus neurons of rodents, Brain Res. Bull., 35 (1994) 505-512.
5. Halverson, K., Fraser, P.E., Kirschner, D.A. and Lansbury, P.T., Jr., Molecular determinants of amyloid deposition in Alzheimer's disease: conformational studies of synthetic β-protein fragments, Biochemistry, 29 (1990) 2639-2644.
6. Henderson, V.W. and Finch, C.E., The neurobiology of Alzheimer's disease, J. Neurosurg., 70 (1989) 335-353.
7. 4 peptides of Alzheimer's disease, J. Mol. Biol., 218 (1991) 149-163.
8. Kaneko, T., Akiyama, H., Nagatsu, I. and Mizuno, N., Immunohistochemical demonstration of glutaminase in catecholaminergic and serotoninergic neurons of rat brain. Brain Res., 507 (1990) 151-154.
9. Kirschner, D.A., Inouye, H., Duffy, L.K., Sinclair, A., Lind, M. and Selkoe, D.L., Synthetic peptide homologous to β protein from Alzheimer disease forms amyloid-like fibrils in vitro, Proc. Natl. Acad. Sci. USA, 84 (1987) 6953-6957.
10. Koh, J., Yang, L.L. and Cotman, C.W., β-Amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage, Brain Res., 533 (1990) 315-320.
11. Kowall, N.W., Beal, M.F., Busciglio, J., Duffy, L.K. and Yankner, B.A., An in vivo model for the neurodegenerative effects of beta-amyloid and protection by substance P, Proc. Natl. Acad. Sci. USA, 88 (1991) 7247-7251.
12. Kowall, N.W., McKee, A.C., Yankner, B.A. and Beal, M.F., In vivo neurotoxicity of beta amyloid β(1-40) and β(25-35) fragment, Neurobiol. Aging, 13 (1992) 537-542.
13. Mattson, M.P., Cheng, B., Davis, D., Bryant, K., Lieberbung, I. and Rydel, R.E., β-Amyloid peptide destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity, J. Neurosci., 12 (1992) 376-389.
14. Pike, C.J., Brudick, D., Walencewicz, A.J., Glabe, C.G. and Cotman, C.W., Neurodegeneration induced by β-amyloid peptides in vitro: the role of peptide assembly state, J. Neurosci., 13 (1993) 1676-1687.
15. Rush, D.K., Aschmies, S. and Merriman, M.C., Intracerebral β-amyloid(25-35) produces tissue damage: is it neurotoxic? Neurobiol. Aging, 13 (1992) 591-594.
16. Soto, C., Brañes, M.C., Alvarez, J. and Inestrosa, N.C., Structural determinants of the Alzheimer's amyloid β-peptide, J. Neurochem., 63 (1994) 1191-1198.
17. Soto, C., Castaño, E.M., Frangiones, B. and Inestrosa, N.C., The α-helical to β-strand transition in the amino-terminal fragment of the amyloid β-peptide modulates amyloid formation, J. Biol. Chem., 270 (1995) 3063-3067.
18. Terzi, E., Holzemann, G. and Seelig, J., Alzheimer β-amyloid peptide 25-35: electrostatic interactions with phospholipid membranes, Biochemistry, 33 (1994) 7434-7441.
19. Wang, Z., Liu, R.-H., Reddy, V.K. and Barnes, C.D., Hippocampal β-amyloid reduces locus coeruleus glutamate and tyrosine hydroxylase, Brain Res. Bull., 35 (1994) 485-491.
20. Yankner, B.A., Duffy, L.K. and Kirschner, D.A., Neurotrophic and neurotoxic effects of amyloid β protein: reversal by tachykinin neuropeptides, Science, 250 (1990) 279-282.