Heparin's anti-inflammatory effects require glucosamine 6-O-sulfation and are mediated by blockade of L- and P-selectins

Journal of Clinical Investigation

Volumn 110, Issue 1, 2002, Pages 127-136

  Wang, Lianchun ^a   Brown, Jillian R ^a   Varki, Ajit ^a,b   Esko, Jeffrey D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICOAGULANT AGENT; ANTIINFLAMMATORY AGENT; ANTITHROMBOCYTIC AGENT; GLUCOSAMINE DERIVATIVE; HEPARIN; HEPARINOID; L SELECTIN; OXAZOLE DERIVATIVE; PADGEM PROTEIN; SELECTIN; THIOGLYCOLIC ACID; THROMBIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL ADHESION; CONTROLLED STUDY; DELAYED HYPERSENSITIVITY; DRUG POTENCY; ENDOTHELIUM CELL; IMMOBILIZED CELL; INFLAMMATION; MALE; NONHUMAN; PERITONITIS; PRIORITY JOURNAL; PROTEIN BINDING; SULFATION;

EID: 0036308072     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI0214996     Document Type: Article

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