Pharmacology of selectin inhibitors in ischemia/reperfusion states

Annual Review of Pharmacology and Toxicology

Volumn 40, Issue , 2000, Pages 283-294

  Lefer, David J ^a  

^a LOUISIANA STATE UNIVERSITY   (United States)

Author keywords

Coronary circulation; Endothelium; Myocardial injury; P selectin; Sialyl Lewis(x)

Indexed keywords

ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; L SELECTIN; MONOCLONAL ANTIBODY; PADGEM PROTEIN;

DRUG RESEARCH; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HUMAN; INFLAMMATORY DISEASE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; REPERFUSION INJURY; REVIEW;

ANIMALS; ANTIBODIES, MONOCLONAL; ISCHEMIA; MEMBRANE GLYCOPROTEINS; MICE; MICE, KNOCKOUT; NITRIC OXIDE DONORS; OLIGOSACCHARIDES; REPERFUSION INJURY; SELECTINS;

EID: 0034074182     PISSN: 03621642     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.pharmtox.40.1.283     Document Type: Review

References (10)

1. Bevilacqua M, Nelson RM. 1993. Selectins. J. Clin. Invest. 91:379-87
2. McEver RP. 1991. GMP-140: a receptor for neutrophils and monocytes on activated platelets and endothelium. J. Cell. Biochem. 45:156-61
3. Lorant DE, Patel KD, McIntyre TM, McEver RP, Prescott SM, Zimmerman GA. 1991. Co-expression of GMP-140 and PAF by endothelium stimulated by histamine or thrombin: a juxtacrine system for adhesion and activation of neutrophils. J. Cell. Biol. 115:223-34
4. Bevilacqua MB, Stengelin S, Gimbrone MA Jr, Seed B. 1989. Endothelial leukocyte adhesion molecule molecule-1: an inducible receptor for neutrophils related to complement regulatory proteins and lectins. Science 243:1160-65
5. Butcher EC. 1991. Leukocyte-endothelial cell recognition: three (or more) steps to specificity and diversity. Cell 67: 1033-36
6. Lefer AM, Lefer DJ. 1996. The role of nitric oxide and cell adhesion molecules on the microcirculation in ischaemia-reperfusion. Cardiovasc. Res. 32:743-51
7. Weiss SJ. 1989. Tissue destruction by neutrophils. N. Engl. J. Med. 320:365-76
8. Tsao PS, Aoki N, Lefer DJ, Johnson G, Lefer AM. 1990. Time course of endothelial dysfunction and myocardial injury during myocardial ischemia and reperfusion in the cat. Circulation 82:1402-12
9. Weyrich AS, Buerke M, Albertine KH, Lefer AM. 1995. Time course of coronary vascular endothelial molecule expression during reperfusion of the ischemic feline myocardium. J. Leuk. Biol. 57:45-55
10. Ma XL, Weyrich AS, Lefer DJ, Lefer AM. 1993. Diminished basal nitric oxide release after myocardial ischemia and reperfusion promotes neutrophil adherence to the coronary endothelium. Circ. Res. 72:403-12