Impaired primary T cell responses in L-selectin-deficient mice

Journal of Experimental Medicine

Volumn 183, Issue 2, 1996, Pages 589-598

  Xu, Jianchao ^a   Grewal, Iqbal S ^a   Geba, Gregory P ^a   Flavell, Richard A ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CYTOKINE; DNA; FREUND ADJUVANT; GAMMA INTERFERON; IMMUNOGLOBULIN; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; INTERLEUKIN 2; INTERLEUKIN 4; KEYHOLE LIMPET HEMOCYANIN; L SELECTIN; OXAZOLONE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELLULAR IMMUNITY; CONTACT SENSITIVITY; CONTROLLED STUDY; DELAYED HYPERSENSITIVITY; FEMALE; GENE TARGETING; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMMUNIZATION; LYMPHOCYTE PROLIFERATION; MALE; MEMORY CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

ANIMALS; ANTIBODY FORMATION; CYTOKINES; DERMATITIS, CONTACT; HEMOCYANIN; HYPERSENSITIVITY, DELAYED; IMMUNIZATION; IMMUNOLOGIC MEMORY; L-SELECTIN; LYMPH NODES; LYMPHOCYTE ACTIVATION; MICE; MICE, MUTANT STRAINS; NEUTROPHILS; T-LYMPHOCYTES;

EID: 0030052192     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.183.2.589     Document Type: Article

References (34)

1. Mackay, C.R. 1992, Migration pathways and immunologic memory among T lymphocytes. Semin. Immunol 4:51-58.
2. Picker, L.J., and E.C. Butcher. 1992. Physiological and molecular mechanisms of lymphocyte homing. Annu. Rev. Immunol. 10:561-591.
3. Butcher, E.G. 1986. The regulation of lymphocytic traffic. Curr. Top Microbiol. Immunol. 128:85-122.
4. Woodruff, J.J., L.M. Clarke, and Y.H. Chin. 1987. Specific cell adhesion mechanisms determining migration pathways of recirculating lymphocytes. Annu. Rev. Immunol. 5:201-222.
5. Yendnock, T., and S.D. Rosen. 1989 Lymphocyte homing. Adv. Immunol 44:313-378.
6. Geoffroy, J.S , and S.D. Rosen. 1989. Demonstration that a lectin-like receptor directly mediates adhesion of lymphocytes to high endothelial venules of lymph nodes J. Cell Blol. 109: 2463-2469.
7. Gallatin, W.M., I.L. Weissman, and E.G. Butcher. 1983. A surface molecule involved in organ-specific homing of lymphocytes. Nature (Lond.). 3044:30-34.
8. Hamann, A., D. Jablonski-Westrich, P. Jonas, and H. Thiele. 1991. Homing receptors reexamined: mouse LECAM-1 (MEL-14 antigen) is involved in lymphocyte migration into gut-associated lymphoid tissue. Eur. J. Immunol 21:2925-2929.
9. Watson, S R., C. Fennie, and L.A. Lasky. 1991. Neutrophil influx into an inflammatory site inhibited by a soluble homing receptor-IGg chimera. Nature (Lond.). 349:164-167.
10. Butcher, E.C. 1991. Leukocyte-endothelial cell recognition: three (or more) steps to specificity and diversity. Cell. 67: 1033-1036.
11. Springer, T.A. 1994. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell. 76:301-314.
12. Dawson, J , A.D. Sedgwick, J.C. Edwards, and P. Lees. 1992. The monoclonal antibody MEL-14 can block lymphocyte migration into a site of chronic inflammation. Eur. J. Immunol. 22.1647-1650.
13. Pizcueta, P., and F.W. Luscinskas. 1994. Monoclonal antibody blockade of L-selectin inhibits mononuclear leukocyte recruitment to inflammatory sites in vivo. Am. J. Pathol. 145: 461-469.
14. Lepault, F., M.C. Gagnerault, C, Faveeuw, and P. Boitard. 1994. Recirculation, phenotype and functions of lymphocytes in mice treated with monoclonal antibody MFT-14. Eur. J. Immunol. 24:3106-3112.
15. Dailey, M.O., C.G. Fathman, E.C. Butcher, E. Pillemer, and I. Weissman. 1982. Abnormal migration of T lymphocyte clones. J. Immunol. 128:2134-2136.
16. + T cells in lymph node and lung of mice with Sendai virus pneumonia by LECAM-1 and CD45RB phenotype. J. Immunol. 150:5494-5500.
17. Jung, T.M., W.M. Gallatin, I.L. Weissman, and M.O. Daiiey. 1988. Downregulation of homing receptors after T cell activation. J. Immunol. 141:4110-4117.
18. Kanof, M.E., and S.P. James. 1988. Leu-8 antigen expression is diminished during cell activation but does not correlate with effector function of activated T lymphocytes, J. Immunol. 140:3701-3706.
19. Gallatin, M., T.P. John, M. Siegelman, R. Reichert, E.C. Butcher, and I.L. Weissman. 1986. Lymphocyte homing receptors. Cell. 44:673-680.
20. Bradley, L.M., D.D. Duncan, K. Yoshimoto, and S.L. Swain. 1993. Memory effectors: a potent, IL-4-secreting helper T cell population that develops in vivo after restimulation with antigen. J. Immunol. 150:3119-3130.
21. + memory T cells from the spleen lack MEL-14, the lymph node homing receptor. J. Immunol. 148:324-331.
22. Bradley, L.M., S.R. Watson, and S.L. Swain. 1994. Entry of naive CD4 T cells into peripheral lymph nodes requires L-selectin. J. Exp. Med. 180:2401-2406.
23. Arbones, M.L., D.C. Ord, K. Ley, H. Ratch, C. Maynard-Curry, G. Otten, D.J. Capon, and T.F. Tedder. 1994. Lymphocyte homing and leukocyte rolling and migration are impaired in L-selectin-deficient mice. Immunity. 1:247-260.
24. Hogan, B., R. Beddington, F. Costantini, and E. Lacy. 1994. Manipulating the Mouse Embryo. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
25. Kamogawa, Y., L.A. Minasi, S.R. Carding, K. Bottomly, and R. Flavell. 1993. The relationship of IL-4 and IFN gamma-producing T cells studied by lineage ablation of IL-4-producing cells. Cell. 75:985-995.
26. Thomas, K.R., and M.R. Capecchi. 1987. Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells. Cell. 51:503-512.
27. Dowbenko, D.J., A. Diep. B.A. Taylor, A.J. Lusis, and L.A. Lasky. 1991. Characterization of the murine homing receptor gene reveals correspondence between protein domains and coding exons. Genomics. 9:270-277.
28. Tedder, T.F., D.A. Steeber, and P. Pizcueta. 1995. L-selectin-deficient mice have impaired leukocyte recruitment into inflammatory sites. J. Exp. Med. 181:2259-2264.
29. Kishimoto, T.K., M.A. Jutila, and E.G. Butcher. 1990. Identification of a human peripheral lymph node homing receptor: a rapidly down-regulated adhesion molecule. Proc. Natl. Acad. Sci. USA. 87:2244-2248.
30. Streeter, P.R., B.T. Rouse, and E.C. Butcher. 1988. Immunohistologic and functional characterization of a vascular addressin involved in lymphocyte homing into peripheral lymph nodes. J. Cell Biol. 107:1853-1862.
31. Berg, E.L., L.A. Goldstein, M.A. Jutila, M. Nakache, L.J. Picker, P.R. Streeter, N.W. Wu, D. Zhou, and E.C. Butcher. 1989. Homing receptors and vascular addressins: cell adhesion molecules that direct lymphocyte traffic. Immunol. Rev. 108:5-18.
32. Murakawa, Y., Y. Minami, W. Strober, and S.P. James. 1992. Association of human lymph node homing receptor (Leu 8) with the TCR/CD3 complex. J. Immunol. 148:1771-1776.
33. Mackay, C.R., W.L. Marston, and L. Dudler. 1990. Naive and memory T cells show distinct pathways of lymphocyte recirculation. J. Exp. Med. 171:801-817.
34. Morimoto, C., N.L. Letvin, J.A. Distaso, W.R. Aldrich, and S.F. Schlossman. 1985. The isolation and characterization of the human suppressor inducer T cell subset. J. Immunol. 134: 1508-1515.