Effects of a monoclonal antibody directed against P-selectin after myocardial ischemia and reperfusion

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 270, Issue 1 39-1, 1996, Pages

  Lefer, David J ^a   Flynn, David M ^a   Buda, Andrew J ^a  

^a TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

endothelium; myocardial blood flow; myocardial contractility; neutrophils

Indexed keywords

MONOCLONAL ANTIBODY; PADGEM PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY DETECTION; ARTICLE; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; DOG; ENDOTHELIUM CELL; ENZYME ACTIVITY; HEART FUNCTION; HEART MUSCLE BLOOD FLOW; HEART MUSCLE CONTRACTILITY; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; TISSUE INJURY;

EID: 0030042753     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1996.270.1.h88     Document Type: Article

References (36)

1. Bevilacqua, M. P., J. S. Pober, D. L. Mendrick, R. S. Cotran, and M. A. Gimbrone. Identification of an inducible endothelial-leukocyte adhesion molecule. Proc. Natl. Acad. Sci. USA 84: 9238-9242, 1987.
2. Bolli, R., W.-X. Zhu, J. I. Thornby, P. G. O'Neill, and R. Roberts. Time course and determinants of recovery of function after reversible ischemia in conscious dogs. Am. J. Physiol. 254 (Heart Circ. Physiol. 23): H102-H114, 1988.
3. Bradley, P. P., D. A. Priebat, R. D. Christensen, and G. R. Rothstein. Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker. J. Invest. Dermatol. 78: 206-209, 1982.
4. Buda, A. J., R. J. Zotz, and K. P. Gallagher. The effect of inotropic stimulation on normal and ischemic myocardium after coronary occlusion. Circulation 76: 163-172, 1987.
5. Dreyer, W. J., L. H. Michael, M. W. West, C. W. Smith, R. Rothlein, R. D. Rossen, D. C. Anderson, and M. L. Entman. Neutrophil accumulation in ischemic canine myocardium: insights into time course, distribution, and mechanism of localization during early reperfusion. Circulation 84: 400-411, 1991.
6. Engler, R. L., and J. W. Covell. Granulocytes cause reperfusion ventricular dysfunction after 15-minute ischemia in the dog. Circ. Res. 61. 20-28, 1987.
7. Harlan, J. M., R. K. Winn, N. B. Vedder, C. M. Doerschuk, and C. L. Rice. In vivo models of leukocyte adherence to endothelium. In: Adhesion: Its Role in Inflammatory Disease, edited by J. M. Harlan and D. Y. Liu. New York: Freeman, 1991, p. 117-150.
8. Hattori, R., K. K. Hamilton, R. D. Fugate, R. P. McEver, and P. J. Sims. Stimulated secretion of endothelial von Willebrand factor is accompanied by rapid redistribution to the cell surface of the intracellular granule membrane protein GMP-140. J. Biol. Chem. 264: 7768-7771, 1989.
9. Heyman, M. A., B. D. Payne, J. I. E. Hoffman, and A. M. Rudolph. Blood flow measurements with radionuclide-labeled particles. Prog. Cardiovasc. Dis. 20: 55-79, 1977.
10. Lasky, L. A. Selectins: interpreters of cell-specific carbohydrate information during inflammation. Science Wash. DC 258: 964-969, 1992.
11. Lefer, D. J., K. Nukanishi, W. E. Johnston, and J. Vinten-Johansen. Antineutrophil and myocardial protecting actions of a novel nitric oxide donor after acute myocardial ischemia and reperfusion in dogs. Circulation 88: 2337-2350, 1993.
12. Lefer, D. J., S. M. L. Shandelya, C. V. Serrano, L. C. Becker, P. Kuppusamy, and J. L. Zweier. Cardioprotective actions of a monoclonal antibody against CD-18 in myocardial ischemia-reperfusion injury. Circulation 88: 1779-1787, 1993.
13. Lorant, D. E., K. D. Patel, T. M. McIntyre, R. P. McEver, S. M. Prescott, and G. A. Zimmerman. Coexpression of GMP-140 and PAF by endothelium stimulated by histamine or thrombin: a juxtacrine system for adhesion and activation of neutrophils. J. Cell Biol. 115: 223-234, 1991.
14. Lorant, D. E., M. K. Topham, R. E. Whatley, R. P. McEver, T. M. McIntyre, S. M. Prescott, and G. A. Zimmerman. Inflammatory roles of P-selectin. J. Clin. Invest. 92: 559-570, 1993.
15. Lucchesi, B. R. Modulation of leukocyte-mediated myocardial reperfusion injury. Annu. Rev. Physiol. 84: 400-411, 1991.
16. Ma, X.-L., D. J. Lefer, A. M. Lefer, and R. Rothlein. Coronary endothelial and cardiac protective effects of a monoclonal antibody to intercellular adhesion molecule-1 in myocardial ischemia and reperfusion. Circulation 86: 937-946, 1992.
17. Ma, X.-L., P. S. Tsao, and A. M. Lefer. Antibody to CD-18 exerts endothelial and Cardioprotective effects in myocardial ischemia and reperfusion. J. Clin. Invent. 88: 1237-1243, 1991.
18. Mazzone, A. S., S. De Servi, G. Ricevuti, G. Mazzucchelli, G. Fossati, D. Passoti, E. Bramucci, L. Angoli, F. Marsico, G. Specchia, and A. Notario. Increased expression of neutrophil and monocyte adhesion molecules in unstable coronary artery disease. Circulation 88: 358-363, 1993.
19. McEver, R. P. Leukocyte interactions mediated by selectins. Thromb. Haemostasis 66: 80-87, 1991.
20. McEver, R. P. Selectins: novel receptors that mediate leukocyte adhesion during inflammation. Thromb. Haemostasis 65: 223-228, 1991.
21. McEver, R. P. GMP-140, a receptor that mediates interactions of leukocytes with activated platelets and endothelium. Trends Cardiol. Med. 1: 152-156, 1991.
22. McEver, R. P., J. H. Beckstead, K. L. Moore, L. Marshall-Carlson, and D. F. Bainton. GMP-140, a platelet α-granule membrane protein, is also synthesized by vascular endothelial cells and is localized in Weibel-Palade bodies. J. Clin. Invest. 84: 92-99, 1989.
23. Mullane, K. M., R. Kraemer, and B. Smith. Myeloperoxidase activity as a quantitative assessment of neutrophil infiltration into ischemic myocardium. J. Pharmacol. Methods 14: 157-167, 1985.
24. Mulligan, M. S., M. J. Polly, R. J. Bayer, M. F. Nunn, J. C. Paulson, and P. A. Ward. Neutrophil-dependent acute lung injury: requirement for P-selectin (GMP-140). J. Clin. Invest. 90: 1600-1607, 1992.
25. Nakanishi, K., J. Vinten-Johansen, D. J. Lefer, Z. Zhao, W. C. Fowler, D. S. McGee, and W. E. Johnston. Intracoronary L-arginine during reperfusion improves endothelial function and reduces infarct size. Am. J. Physiol. 263 (Heart Circ. Physiol. 32): H1650-H1658, 1992.
26. Patel, K. D., G. A. Zimmerman, S. M. Prescott, R. P. McEver, and T. M. McIntyre. Oxygen radicals induce human endothelial cells to express GMP-140 and bind neutrophils. J. Cell Biol. 112: 749-759, 1991.
27. Paulson, J. C. Selectin/carbohydrate-mediated adhesion of leukocytes. In: Adhesion: Its Role in Inflammatory Disease, edited by J. M. Harlan and D. Y. Liu. New York: Freeman, 1991, p 19-38
28. Romson, J. L., B. G. Hook, S. L. Kunkel, G. D. Abrams, M. A. Schork, and B. R. Lucchesi. Reduction of the extent of ischemic myocardial injury by neutrophil depletion in the dog. Circulation 67: 1016-1023, 1983.
29. Schaper, W., M. Hofmann, K.-D. Muller, K. Genth, and M. Carl. Experimental occlusion of two small coronary arteries in the same heart: a new validation method for infarct size manipulation. Basic Res. Cardiol. 74: 224-229, 1979.
30. Simpson, P. J., R. F. Todd, J. C. Fantone, J. K. Mickelson, J. D. Griffin, and B. R. Lucchesi. Reduction of experimental canine myocardial reperfusion injury by a monoclonal antibody (anti-Mol, and anti-CD11b) that inhibits leukocyte adhesion. J. Clin. Invest. 81: 624-629, 1988.
31. Smith, C. W., D. C. Anderson, A. A. Taylor, R. D. Rossen, and M. L. Entman. Leukocyte adhesion molecules and myocardial ischemia. Trends Card. Med. 1: 167-170, 1991.
32. Stenberg, P. E., R. P. McEver, M. A. Shuman, Y. V. Jaques and D. F. Bainton. A platelet alpha-granule membrane protein (GMP-140) is expressed on the plasma membrane after activation. J. Cell Biol. 101: 880-886, 1985.
33. Weyrich, A. S., X.-L. Ma, D. J. Lefer, K. H. Albertine, and A. M. Lefer. In vivo neutralization of P-selectin protects feline heart and endothelium in myocardial ischemia and reperfusion injury. J. Clin. Invest. 91: 2620-2629, 1993.
34. Winn, R. K., D. Liggitt, N. B. Vedder, J. C. Paulson, and J. M. Harlan. Anti-P-selectin monoclonal antibody attenuates reperfusion injury to the rabbit ear. J. Clin. Invest. 92: 2042-2047, 1993.
35. Winquist, R. J., P. P. Frei, L. G. Letts, G. Y. Van, L. K. Andrews, R. Rothlein, W. J. Dreyer, C. W. Smith, and T. H. Hintze. Monoclonal antibody to intercellular adhesion molecule-1 protects against myocardial ischemia/reperfusion damage in anesthetized monkeys (Abstract). Circulation 86, Suppl 1: 1-79, 1992.
36. Yamazaki, T., Y. Seko, T. Tamatani, M. Miyasaka, H. Yagita, K. Okumura, R. Nagai, and Y. Yazaki. Expression of intercellular adhesion molecule-1 in rat heart with ischemia/reperfusion and limitation of infarct size by treatment with antibodies against cell adhesion molecules. Am. J. Pathol. 143: 410-418, 1993.