Helicobacter priori inhibits the G1 to S transition in AGS gastric epithelial cells

Cancer Research

Volumn 59, Issue 10, 1999, Pages 2277-2281

  Shirin, Haim ^a,b   Sordillo, Emilia Mia ^a   Oh, Sung H ^a   Yamamoto, Hirofumi ^b   Delohery, Thomas ^c   Weinstein, I Bernard ^b   Moss, Steven F ^a  

^a ST LUKE S ROOSEVELT HOSPITAL CENTER   (United States)

^b Columbia University ^*  (United States)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN A; CYCLIN D; CYCLIN E; BACTERIAL ANTIGEN; BACTERIAL PROTEIN; CAGA PROTEIN, HELICOBACTER PYLORI; CELL CYCLE PROTEIN; FLUOROURACIL; HYBRID PROTEIN;

APOPTOSIS; ARTICLE; CARCINOGENESIS; CELL CYCLE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL GROWTH; CELL PROLIFERATION; CELL STRUCTURE; GENE EXPRESSION; HELICOBACTER PYLORI; HUMAN; HUMAN CELL; PRIORITY JOURNAL; STOMACH CANCER; TRANSCRIPTION REGULATION; BIOSYNTHESIS; CELL CULTURE; CULTURE MEDIUM; DRUG EFFECT; EPITHELIUM CELL; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MICROBIOLOGY; ONCOGENE; PATHOLOGY; PHYSIOLOGY; STOMACH MUCOSA; STOMACH TUMOR;

ANTIGENS, BACTERIAL; APOPTOSIS; BACTERIAL PROTEINS; CELL CYCLE PROTEINS; CULTURE MEDIA, SERUM-FREE; EPITHELIAL CELLS; FLUOROURACIL; G1 PHASE; GASTRIC MUCOSA; GENE EXPRESSION REGULATION, BACTERIAL; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, FOS; HELICOBACTER PYLORI; HUMANS; RECOMBINANT FUSION PROTEINS; S PHASE; STOMACH NEOPLASMS; TUMOR CELLS, CULTURED;

EID: 0033561808     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Kuipers, E. J. Relationship between Helicobacter pylori, atrophic gastritis and gastric cancer. Aliment. Pharmacol. Ther., 12 (Suppl. 1): 25-36, 1998.
2. IARC, Schistosomes, Liver Flukes and Helicobacter pylori. Monographs on the Evaluation of Carcinogenic Risks to Humans. IARC Sci. Publ., 61: 1-241, 1994.
3. Honda, S., Fujioka, T., Tokieda, M., Satoh, R., Nishizono, A., and Nasu, M. Development of Helicobacter pylori-induced gastric carcinoma in mongolian gerbils. Cancer Res., 58: 4255-4259, 1998.
4. Watanabe, T., Tada, M., Nagai, H., Sasaki, S., and Nakao, M. Helicobacter pylori infection induces gastric cancer in mongolian gerbils. Gastroenterology, 115: 642-648, 1998.
5. Mannick, E. E., Bravo, L. E., Zarama, G., Realpe, J. L., Zhang X-J., Ruiz, B., Fontham, E. T. H., Mera, R., Miller, M. J. S., and Correa, P. Inducible nitric oxide synthase, nitrotyrosine, and apoptosis in Helicobacter pylori gastritis: effect of antibiotics and antioxidants. Cancer Res., 56: 3238-3243, 1996.
6. El-Omar, E. M., Oien, K., El-Nujumi, A., Gillen, D., Wirz, A., Dahill, S., Williams, C., Ardill, J. E., and McColl, K. E. Helicobacter pylori infection and chronic gastric acid hyposecretion. Gastroenterology, 113: 15-24, 1997.
7. Correa, P., Malcom, G., Schmidt, B., Fontham, E., Ruiz, B., Bravo, J. C., Bravo, L. E., Zarama, G., and Realpe, J. L. Antioxidant micronutrients and gastric cancer. Aliment. Pharmacol. Ther., 12 (Suppl. 1): 73-82, 1998.
8. Anti, M., Armuzzi, A., Gasbarrini, A., and Gasbarrini, G. Importance of changes in epithelial cell turnover during Helicobacter pylori infection in gastric carcinogenesis. Gut, 43 (Suppl. 1): S27-S32, 1998.
9. Moss, S. F., Calam, J., Agarwal, B., Wang, S., and Holt, P. R. Induction of gastric epithelial apoptosis by Helicobacter pylori. Gut, 38: 498-501, 1996.
10. Jones, N. L., Shannon, P. T., Cutz, E., Yeger, H., and Sherman, P. Increase in proliferation and apoptosis of gastric epithelial cells early in the natural history of Helicobacter pylori infection. Am. J. Pathol., 151: 1695-1703, 1997.
11. Blaser, M. J., Perez-Perez, G. I., Kleanthous, H., Cover, T. L., Peek, R. M., Chyou, P. H., Stemmermann, G. N., and Nomura, A Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach. Cancer Res., 55: 2111-2115, 1995.
12. Peek, R. M., Moss, S. F., Tham, K. T., Perez-Perez, G. I., Miller, G. G., Atherton, J. C., Holt, P. R., and Blaser, M. J. Helicobacter pylori cagA+ strains and dissociation of gastric epithelial proliferation from apoptosis. J. Natl. Cancer Inst., 89: 863-868, 1997.
13. Chen, G., Sordillo, E. M., Ramey, W. G., Reidy, J., Holt, P. R., Krajewski, S., Reed, J. C., Blaser, M. J., and Moss, S. F. Apoptosis in gastric epithelial cells is induced by Helicobacter pylori and accompanied by increased expression of Bak. Biochem. Biophys. Res. Commun., 39: 626-632, 1997.
14. Wagner, S., Beil, W., Westermann, J., Logan, R. P. H., Bock, C. T., Trautwein, C., Bleck, J. S., and Manns, M. P. Regulation of gastric epithelial cell growth by Helicobacter pylori: evidence for a major role of apoptosis. Gastroenterology, 113: 1836-1847, 1997.
15. Fan, X., Crowe, S. E., Behar, S., Gunasena, H., Ye, G., Haeberle, H., Van Houten, N., Gourley, W. K., Ernst, P. B., and Reyes, V. E. The effect of class II major histocompatibility complex expression on adherence of Helicobacter pylori and induction of apoptosis in gastric epithelial cells: a mechanism for T helper cell type l-mediated damage. J. Exp. Med., 187: 1659-1669, 1998.
16. Rudi, J., Kuck, D., Strand, S., von Herbay, A., Mariani, S. M., Krammer, P. H., Galle, P. R., and Stremmel, W. Involvement of the CD95 (APO-1/Fas) receptor and ligand system in Helicobacter pylori-induced gastric epithelial apoptosis. J. Clin. Invest., 102: 1506-1514, 1998.
17. Tummuru, T. K. R., Cover, T. L., and Blaser, M. J. Mutation of the cytotoxin-associated cagA gene does not affect the vacuolating cytotoxin activity of H. pylori. Infect. Immun., 61: 2609-2613, 1994.
18. Riggs, K. J., Saleque, S., Wong, K. K., Merrell, K. T., Lee, J. S., Shi, Y., and Calame, K. Yin-Yang 1 activated the c-myc promoter. Mol. Cell. Biol., 13: 7487-7495, 1993.
19. 1 to multiple cell cycles by lovastatin. Cancer Res., 51: 3602-3609, 1991.
20. Johansen, F. E., and Prywes, R. Serum response factor: transcriptional regulation of genes induced by growth factors and differentiation. Biochim. Biophys. Acta, 1242: 1-10, 1995.
21. Mori, M., Mimori, K., Shiraishi, T., Tanaka, S., Ueo, H., Sugimachi, K., and Akiyoshi, T. p27 expression and gastric carcinoma. Nat. Med., 3: 593, 1997.
22. kipl and degree of malignancy in human breast and colorectal cancers. Proc. Natl. Acad. Sci. USA, 94: 6382-6385, 1997.
23. 2/M phase. Mol. Microbiol., 24: 1095-1107, 1997.
24. 2-phase cell cycle block. Infect. Immun., 66: 1934-1940, 1998.
25. Poon, B., Jowett, J. B., Stewart, S. A., Armstrong, R. W., Rishton, G. M., and Chen, I. S. Human immunodeficiency virus type 1 vpr gene induces phenotypic effects similar to those of the DNA alkylating agent, nitrogen mustard. J. Virol., 71: 3961-3971, 1997.
26. Matozaki, T., Sakamoto, C., Matsuda, K., Suzuki, T., Konda, Y., Nakano, O., Wada, K., Uchida, T., Nishisaki, H., Nagao, M., and Kasuga. M. Missense mutations and a deletion of the p53 gene in human gastric cancer. Biochem. Biophys. Res. Commun., 182: 215-223, 1992.
27. Shirin, H., and Moss, S. F. Helicobacter pylori-induced apoptosis. Gut, 43: 592-594, 1998.
28. Keates, S., Hitti, Y. S., Upton, M., and Kelly, C. P. Helicobacter pylori infection activates NF-κ B in gastric epithelial cells. Gastroenterology, 113: 1099-1109, 1997.