Chromatin (dis)organization and cancer: BUR-binding proteins as biomarkers for cancer

Current Cancer Drug Targets

Volumn 2, Issue 2, 2002, Pages 157-190

  Galande, Sanjeev ^a  

^a NATIONAL CENTRE FOR CELL SCIENCE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; BIOLOGICAL MARKER; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NUCLEOLIN; PROTEIN P53;

BASE MISPAIRING; CANCER RESEARCH; CHROMATIN CONDENSATION; COMPLEX FORMATION; DNA REPLICATION; ENHANCER REGION; GENE EXPRESSION REGULATION; HUMAN; MALIGNANT TRANSFORMATION; PROTEIN DNA INTERACTION; PROTEIN DOMAIN; REVIEW; TARGET CELL; TRANSCRIPTION REGULATION;

ANIMALS; ANTIGENS, NUCLEAR; B-LYMPHOCYTES; BASE SEQUENCE; BIOLOGICAL MARKERS; CELL NUCLEUS; CHROMATIN; DNA HELICASES; DNA, NEOPLASM; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, P53; HUMANS; NEOPLASMS; NUCLEAR MATRIX; NUCLEAR PROTEINS; PHOSPHOPROTEINS; RIBONUCLEOPROTEINS; RNA-BINDING PROTEINS;

EID: 0036282608     PISSN: 15680096     EISSN: None     Source Type: Journal    
DOI: 10.2174/1568009023333917     Document Type: Review

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265. Identification of AgNOR Proteins, markers of proliferation related to ribosomal gene activity
266. Importance of interphase nucleolar organizer regions in tumor pathology
267. Binding of MAR-DNA elements by mutant p53: Possible implications for its oncogenic functions
268. Database of p53 gene somatic mutations in human tumors and cell lines: Updated compilation and future prospects
269. p53 function and dysfunction
270. Gain of function mutations in p53
271. The spectrum of mutations at the p53 locus. Evidence for tissue-specific mutagenesis, selection of mutant alleles, and a "gain of function"
272. Heterogeneity of transcriptional activity of mutant p53 proteins and p53 DNA target sequences
273. p53 transactivation through various p53-responsive elements
274. Specific and complex interactions of murine p53 with DNA
275. High affinity MAR-DNA binding is a common property of murine and human mutant p53
276. Specific binding of MAR/SAR DNA-elements by mutant p53
277. Hierarchical binding of DNA fragments derived from scaffold-attached regions: Correlation of properties in vitro and function in vivo
278. Preferential, cooperative binding of DNA topoisomerase II to scaffold-associated regions
279. Two critical hydrophobic amino acids in the N-terminal domain of the p53 protein are required for the gain of function phenotypes of human p53 mutants
280. p53 binds the nuclear matrix in normal cells: Binding involves the proline-rich domain of p53 and increases following genotoxic stress
281. Different structural systems of the nucleus are targets for SV40 large T antigen
282. Cooperation of SV40 large T antigen and the cellular protein p53 in maintenance of cell transformation
283. Mutants with changes within or near a hydrophobic region of simian virus 40 large tumor antigen are defective for binding cellular protein p53
284. Association of p300 and CBP with simian virus 40 large T antigen
285. Binding and modulation of p53 by p300/CBP coactivators
286. The Immunoglobulin heavy-chain matrix-associating regions are bound by bright: A B cell-specific trans-activator that describes a new DNA-binding protein family
287. Identification of a matrix-associated region 5′ of an immunoglobulin heavy chain variable region gene
288. Transcriptional activation by a matrix associating region-binding protein: Contextual requirements for the function of bright
289. Cux/CDP homeoprotein is a component of NF-μNR and represses the immunoglobulin heavy chain intronic enhancer by antagonizing the bright transcription activator
290. Regulation of matrix attachment region-dependent, lymphocyte-restricted transcription through differential localization within promyelocytic leukemia nuclear bodies
291. Structure and function of the HMGI(Y) family of architectural transcription factors
292. HMG I/Y regulates long-range enhancer-dependent transcription on DNA and chromatin by changes in DNA topology
293. Enhanceosomes
294. PU.1-mediated transcription is enhanced by HMG-I(Y)dependent structural mechanisms
295. Ordered recruitment of chromatin modifying and general transcription factors to the IFNβ promoter
296. Hsα expression is associated with the metastatic phenotype in breast cancer
297. Integrin activation controls metastasis in human breast cancer
298. Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion
299. High mobility group HMGI(Y) protein expression in human colorectal hyperplastic and neoplastic diseases
300. Determination of high mobility group I(Y) expression level in colorectal neoplasias: A potential diagnostic marker
301. Pancreatic duct cell carcinomas express high levels of high mobility group I(Y) proteins
302. Sequence-specific DNA recognition by polyamides
303. Inhibition of RNA polymerase II transcription in human cells by synthetic DNA-binding ligands
304. Anti-repression of RNA polymerase II transcription by pyrrole-imidazole polyamides
305. Inhibition of Ets-1 DNA binding and ternary complex formation between Ets-1, NF-κB DNA by a designed DNA-binding ligand
306. Chromatin opening of DNA satellites by targeted sequence-specific drugs
307. Specific gain- and loss-of-function phenotypes induced by satellite-specific DNA-binding drugs fed to Drosophila melanogaster
308. Tallimustine lesions in cellular DNA are AT sequence-specific but not region-specific
309. A Phase I and pharmacokinetic study of tallimustine [PNU 152241 (FCE 24517)] in patients with advanced cancer
310. Carzelesin phase II study in advanced breast, ovarian, colorectal, gastric, head and neck cancer, nonHodgkin's lymphoma and malignant melanoma: A Study of the EORTC Early Clinical Studies Group (ECSG)
311. AT-rich islands in genomic DNA as a novel target for AT-specific DNA-reactive antitumor drugs
312. Identification of base-unpairing region-binding proteins and characterization of their in vivo binding sequences