Effects of supraspinal administration of PG-SPI and PG-KII, two amphibian tachykinin peptides, on nociception in the rat

Peptides

Volumn 21, Issue 11, 2000, Pages 1611-1616

  Improta, Giovanna ^a   Broccardo, Maria ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Analgesia; Naloxone; PG KII; PG SPI; Tachykinin antagonists

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; NALOXONE; NEUROKININ A; NEUROKININ B; PROSTAGLANDIN; SUBSTANCE P; TACHYKININ;

AMINO ACID SEQUENCE; AMPHIBIA; ANALGESIA; ANIMAL EXPERIMENT; ARTICLE; MAMMAL; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; REACTION TIME; RECEPTOR AFFINITY; SPINAL ANESTHESIA;

ANALGESIA; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; HEAT; INDOLES; MALE; NALOXONE; NARCOTIC ANTAGONISTS; NEUROKININ A; NEUROKININ B; OLIGOPEPTIDES; PAIN MEASUREMENT; PAIN THRESHOLD; PIPERIDINES; PYRROLIDONECARBOXYLIC ACID; QUINUCLIDINES; RATS; RATS, WISTAR; RECEPTORS, NEUROKININ-1; RECEPTORS, NEUROKININ-3; SUBSTANCE P; TACHYKININS; TIME FACTORS;

EID: 0033715785     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0196-9781(00)00292-8     Document Type: Article

References (25)

1. Tachykinin NK1 and NK3 selective agonists induce analgesia in the formalin test for tonic pain following intra-VTA or intra-accumbens microinfusions
2. Parallel bioassay of PGSPI, an amphibian acidic SP-like peptide, mammalian basic substance P, and neurokinins A and B on in vitro and in vivo test systems
3. Effect of PG-SPI and PGK-II, two novel and natural tachykinins, on salivary secretion in the rat
4. Receptor characterization of the spinal action of neurokinins on nociception: A three receptor hypothesis
5. SR 142801 behaves as a tachykinin NK3 receptor agonist on a spinal nociceptive reflex in the rat
6. Comparison of the effects of substance P, neurokinin A, physalaemin and eledoisin in facilitating a nociceptive reflex in the rat
7. Facilitation of the tail-flick reflex by noxious cutaneous stimulation in the rat: Antagonism by a substance P analogue
8. Method for determining loss of pain sensation
9. Altered nociception, analgesia and aggression in mice lacking the receptor for substance P
10. In vitro and in vivo biological activities of SR 140333, a novel potent non-peptide tachykinin NK1 receptor antagonist
11. Lack of potent antinociceptive activity by substance P antagonist CP96345 in the rat spinal cord
12. Rat sensory ganglia incorporate radiolabelled amino acid into substance K in vitro
13. In vitro and in vivo biological activities of PG-KII, a novel kassinin-like peptide from the skin of the australian frog, Pseudophrine guntheri
14. Neuropharmacological characterization of SR140333, a non-peptide antagonist of NK1 receptors
15. Characterization of the effects produced by neurokinins and three agonists selective for neurokinin receptor subtypes in a spinal nociceptive reflex of the rat
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21. Further evidence that the tachykinin PG-KII is apotent agonist at central NK3, but not NK1, receptors
22. Neurokinin receptor subtypes characterized by biological assays
23. Six novel tachykinin- and bombesin-related peptides from the skin of the Australian frog pseudophrine guntheri
24. Further evidence suggesting a role for NK2 receptors in nociception
25. Substance P release in the rat periaqueductal gray and preoptic anterior hypothalamus after noxious cold stimulation: Effect of selective mu and kappa opioid agonists