-
1
-
-
0032926368
-
Deletions of the heavy neurofilament subunit tail in amyotrophic lateral sclerosis
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 157-164
-
-
Al-Chalabi, A.1
Andersen, P.M.2
Nilsson, P.3
Chioza, B.4
Andersson, J.L.5
Russ, C.6
Shaw, C.E.7
Powell, J.F.8
Leigh, P.N.9
-
8
-
-
0033934734
-
Mitochondria and the pathogenesis of ALS
-
(2000)
Brain
, vol.123
, pp. 1291-1292
-
-
Beal, M.F.1
-
10
-
-
0027965073
-
Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 8292-8296
-
-
Borchelt, D.R.1
Lee, M.K.2
Slunt, H.S.3
Guarnieri, M.4
Xu, Z.S.5
Wong, P.C.6
Brown R.H., Jr.7
Price, D.L.8
-
12
-
-
0030806228
-
Elevated free nitrotyrosine levels, but not protein-bound nitrotyrosine or hydroxyl radicals, throughout amyotrophic lateral sclerosis (ALS)-like disease implicate tyrosine nitration as an aberrant in vivo property of one familial ALS-linked superoxide dismutase 1 mutant
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 7606-7611
-
-
Bruijn, L.I.1
Beal, M.F.2
Becher, M.W.3
Schulz, J.B.4
Wong, P.C.5
Price, D.L.6
Cleveland, D.W.7
-
13
-
-
0031051485
-
ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions
-
(1997)
Neuron
, vol.18
, pp. 327-338
-
-
Bruijn, L.I.1
Becher, M.W.2
Lee, M.K.3
Anderson, K.L.4
Jenkins, N.A.5
Copeland, N.G.6
Sisodia, S.S.7
Rothstein, J.D.8
-
15
-
-
0032544674
-
Aggregation and motor neuron toxicity of an ALS-linked SOD1 mutant independent from wild-type SOD1
-
(1998)
Science
, vol.281
, pp. 1851-1854
-
-
Bruijn, L.I.1
Houseweart, M.K.2
Kato, S.3
Anderson, K.L.4
Anderson, S.D.5
Ohama, E.6
Reaume, A.G.7
Scott, R.W.8
Cleveland, D.W.9
-
16
-
-
0034595855
-
Generalized potential of adult neural stem cells
-
(2000)
Science
, vol.288
, pp. 1660-1663
-
-
Clarke, D.L.1
Johansson, C.B.2
Wilbertz, J.3
Veress, B.4
Nilsson, E.5
Karlstrom, H.6
Lendahl, U.7
Frisen, J.8
-
20
-
-
0027465098
-
Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: A mouse model of amyotrophic lateral sclerosis
-
(1993)
Cell
, vol.73
, pp. 35-46
-
-
Cote, F.1
Collard, J.F.2
Julien, J.P.3
-
25
-
-
0034932586
-
Stem cell plasticity in muscle and bone marrow
-
(2001)
Ann. NY Acad. Sci.
, vol.938
, pp. 208-220
-
-
Goodell, M.A.1
Jackson, K.A.2
Majka, S.M.3
Mi, T.4
Wang, H.5
Pocius, J.6
Hartley, C.J.7
Majesky, M.W.8
-
27
-
-
0030050727
-
Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis
-
(1996)
Ann. Neurol.
, vol.39
, pp. 147-157
-
-
Gurney, M.E.1
Cutting, F.B.2
Zhai, P.3
Doble, A.4
Taylor, C.P.5
Andrus, P.K.6
Hall, E.D.7
-
29
-
-
0034785483
-
A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2
-
(2001)
Nat. Genet.
, vol.29
, pp. 166-173
-
-
Hadano, S.1
Hand, C.K.2
Osuga, H.3
Yanagisawa, Y.4
Otomo, A.5
Devon, R.S.6
Miyamoto, N.7
Showguchi-Miyata, J.8
-
35
-
-
0037022339
-
Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS)
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 1604-1609
-
-
Howland, D.S.1
Liu, J.2
She, Y.3
Goad, B.4
Maragakis, N.J.5
Kim, B.6
Erickson, J.7
Kulik, J.8
-
36
-
-
0032417251
-
Transgenic mice expressing Alzheimer amyloid precursor proteins
-
(1998)
Exp. Gerontol.
, vol.33
, pp. 883-889
-
-
Hsiao, K.1
-
39
-
-
0035936804
-
Amyotrophic lateral sclerosis. Unfolding the toxicity of the misfolded
-
(2001)
Cell
, vol.104
, pp. 581-591
-
-
Julien, J.P.1
-
40
-
-
0033051815
-
Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis
-
(1999)
Nat. Med.
, vol.5
, pp. 347-350
-
-
Klivenyi, P.1
Ferrante, R.J.2
Matthews, R.T.3
Bogdanov, M.B.4
Klein, A.M.5
Andreassen, O.A.6
Mueller, G.7
Wermer, M.8
-
41
-
-
0032079517
-
Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1
-
(1998)
J. Neurosci.
, vol.18
, pp. 3241-3250
-
-
Kong, J.1
Xu, Z.2
-
42
-
-
0034647003
-
Functional role of caspase-1 and caspase-3 in an ALS transgenic mouse model
-
(2000)
Science
, vol.288
, pp. 335-339
-
-
Li, M.1
Ona, V.O.2
Guegan, C.3
Chen, M.4
Jackson-Lewis, V.5
Andrews, L.J.6
Olszewski, A.J.7
Stieg, P.E.8
-
46
-
-
0030006282
-
A clinical trial of verapamil in amyotrophic lateral sclerosis
-
(1996)
Muscle Nerve
, vol.19
, pp. 511-515
-
-
Miller, R.G.1
Smith, S.A.2
Murphy, J.R.3
Brinkmann, J.R.4
Graves, J.5
Mendoza, M.6
Sands, M.L.7
Ringel, S.P.8
-
49
-
-
0034978562
-
Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration
-
(2001)
Nat. Genet.
, vol.28
, pp. 131-138
-
-
Oosthuyse, B.1
Moons, L.2
Storkebaum, E.3
Beck, H.4
Nuyens, D.5
Brusselmans, K.6
Van Dorpe, J.7
Hellings, P.8
-
51
-
-
15844393658
-
Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury
-
(1996)
Nat. Genet.
, vol.13
, pp. 43-47
-
-
Reaume, A.G.1
Elliott, J.L.2
Hoffman, E.K.3
Kowall, N.W.4
Ferrante, R.J.5
Siwek, D.F.6
Wilcox, H.M.7
Flood, D.G.8
-
54
-
-
0027401203
-
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
-
(1993)
Nature
, vol.362
, pp. 59-62
-
-
Rosen, D.R.1
Siddique, T.2
Patterson, D.3
Figlewicz, D.A.4
Sapp, P.5
Hentati, A.6
Donaldson, D.7
Goto, J.8
-
56
-
-
0025299819
-
Abnormal excitatory amino acid metabolism in amyotrophic lateral sclerosis
-
(1990)
Ann. Neurol.
, vol.28
, pp. 18-25
-
-
Rothstein, J.D.1
Tsai, G.2
Kuncl, R.W.3
Clawson, L.4
Cornblath, D.R.5
Drachman, D.B.6
Pestronk, A.7
Stanch, B.L.8
Coyle, J.T.9
-
59
-
-
0035909330
-
Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila
-
(2001)
Nature
, vol.413
, pp. 739-743
-
-
Steffan, J.S.1
Bodai, L.2
Pallos, J.3
Poelman, M.4
McCampbell, A.5
Apostol, B.L.6
Kazantsev, A.7
Schmidt, E.8
-
60
-
-
0008971296
-
Mutant SOD1 causes motor neuron disease independent of copper chaperone-mediated copper loading
-
(2002)
Nat. Neurosci.
, vol.11
, pp. 11
-
-
Subramaniam, J.R.1
Lyons, W.E.2
Liu, J.3
Bartnikas, T.B.4
Rothstein, J.5
Price, D.L.6
Cleveland, D.W.7
Gitlin, J.D.8
Wong, P.C.9
-
62
-
-
0035291107
-
Adenoviral gene transfer of glial cell line-derived neurotrophic factor to injured adult motoneurons
-
(2001)
Hum. Cell
, vol.14
, pp. 7-15
-
-
Watabe, K.1
Sakamoto, T.2
Ohashi, T.3
Kawazoe, Y.4
Oyanagi, K.5
Takeshima, T.6
Inoue, K.7
Eto, Y.8
Kim, S.U.9
-
63
-
-
0029053881
-
An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria
-
(1995)
Neuron
, vol.14
, pp. 1105-1116
-
-
Wong, P.C.1
Pardo, C.A.2
Borchelt, D.R.3
Lee, M.K.4
Copeland, N.G.5
Jenkins, N.A.6
Sisodia, S.S.7
Cleveland, D.W.8
Price, D.L.9
-
64
-
-
0035718801
-
In vivo gene electroporation of glial cell line-derived neurotrophic factor (GDNF) into skeletal muscle of SOD1 mutant mice
-
(2001)
Neurochem. Res.
, vol.26
, pp. 1201-1207
-
-
Yamamoto, M.1
Kobayashi, Y.2
Li, M.3
Niwa, H.4
Mitsuma, N.5
Ito, Y.6
Muramatsu, T.7
Sobue, G.8
-
65
-
-
0034785509
-
The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis
-
(2001)
Nat. Genet.
, vol.29
, pp. 160-165
-
-
Yang, Y.1
Hentati, A.2
Deng, H.X.3
Dabbagh, O.4
Sasaki, T.5
Hirano, M.6
Hung, W.Y.7
Ouahchi, K.8
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