Potentiation of mitogenic activity of platelet-derived growth factor by physiological concentrations of insulin via the MAP kinase cascade in Rat A10 vascular smooth muscle cells

International Journal of Experimental Diabetes Research

Volumn 3, Issue 2, 2002, Pages 131-144

  Yamada, Hitomi ^a   Tsushima, Toshio ^a   Murakami, Hitomi ^a   Uchigata, Yasuko ^a   Iwamoto, Yasuhiko ^a  

^a TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

Author keywords

Atherosclerosis; Insulin; MAPK; PDGF; VSMC

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; DNA; INSULIN; MANUMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PLATELET DERIVED GROWTH FACTOR; PROTEIN KINASE B; RAPAMYCIN; RAS PROTEIN; S6 KINASE; WORTMANNIN;

ANIMAL CELL; ATHEROSCLEROSIS; CELL LINE; CELL MIGRATION; CELL PROLIFERATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIABETIC ANGIOPATHY; DNA SYNTHESIS; EMBRYO; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENETIC TRANSFECTION; HYPERINSULINEMIA; MITOGENICITY; NONHUMAN; PRIORITY JOURNAL; RAT; REVIEW; RISK FACTOR; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

ANIMALS; AORTA, THORACIC; CELL DIVISION; CELLS, CULTURED; DNA; HUMANS; INSULIN; KINETICS; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASES; MUSCLE, SMOOTH, VASCULAR; PLATELET-DERIVED GROWTH FACTOR; RATS; RECOMBINANT PROTEINS; SWINE; TIME FACTORS;

EID: 0036248493     PISSN: 15604284     EISSN: None     Source Type: Journal    
DOI: 10.1080/15604280214489     Document Type: Review

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