Treatment of vascular smooth muscle cells with antisense phosphorothioate oligodeoxynucleotides directed against p42 and p44 mitogen-activated protein kinases abolishes DNA synthesis in response to platelet-derived growth factor

Biochemical Journal

Volumn 320, Issue 1, 1996, Pages 123-127

  Robinson, Caspar J M ^a   Scott, Pamela H ^a   Allan, Andrew B ^a   Jess, Thomas ^b   Gould, Gwyn W ^b   Plevin, Obin ^a  

^a UNIVERSITY OF STRATHCLYDE   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; MITOGEN ACTIVATED PROTEIN KINASE; OLIGODEOXYNUCLEOTIDE PHOSPHOROTHIOATE; PLATELET DERIVED GROWTH FACTOR;

ANIMAL CELL; ARTICLE; CELL LYSATE; CONTROLLED STUDY; DNA SYNTHESIS; DNA SYNTHESIS INHIBITION; MITOGENESIS; NONHUMAN; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE; VASCULAR SMOOTH MUSCLE;

ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELLS, CULTURED; DNA REPLICATION; ENZYME ACTIVATION; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; MUSCLE, SMOOTH, VASCULAR; OLIGONUCLEOTIDES, ANTISENSE; PLATELET-DERIVED GROWTH FACTOR; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; RATS; THIONUCLEOTIDES;

ANIMALIA;

EID: 0029795987     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/bj3200123     Document Type: Article

References (28)

1. Malarkey, K., Belham, C. M., Paul, A., Graham, A., McLees, A., Scott, P. H. and Plevin, R. (1995) Biochem. J. 309, 361-375
2. Lin, L.-L., Wartman, M., Yin, A. Y., Knopf, J. L., Seth, A. and Davis, R. J. (1993) Cell 72, 269-278
3. Gille, H., Kortenjann, M., Thomae, O., Moomaw, C., Slaughter, C., Cobb, M. H. and Shaw, P. E. (1995) EMBO J. 14, 951-962
4. Merrall, N. W., Plevin, R. J., Stokoe, D., Cohen, P., Nebreda, A. R. and Gould, G. W. (1993) Biochem. J. 295, 351-355
5. Gould, G. W., Cuenda, A., Thomson, F. J. and Cohen, P. (1995) Biochem. J. 311, 735-738
6. Pages, G., Lenormand, P., L'Allemain, G., Chambard, J. C., Meloche, S. and Pouyssegur, J. (1993) Proc. Natl. Acad. Sci. U.S.A. 90, 8319-8323
7. Cowley, S., Paterson, H., Kemp, P. and Marshall, C. J. (1994) Cell 77, 841-852
8. Duff, J. L., Berk, B. C. and Corson, M. A. (1992) Biochem. Biophys. Res. Commun. 188, 257-264
9. Granot, Y., Erikson, E., Fridman, H., van Putten V., Williams, B., Schrier, R. W. and Maller, J. L. (1993) J. Biol. Chem. 268, 9564-9569
10. Molloy, C. J., Taylor, D. S. and Weber, H. (1993) J. Biol. Chem. 268, 7338-7345
11. Malarkey, K., McLees, A., Paul, A, Gould, G. W. and Plevin, R. (1996) Cell. Signalling 8, 123-129
12. Sale, E. M., Atkinson, G. P. and Sale, G. J. (1995) EMBO J. 14, 674-684
13. Gardner, A. M., Lange-Carter, C. A., Vaillancourt, R. R. and Johnson, G. L. (1994) Methods Enzymol. 238, 258-270
14. Janknecht, R., de Martynoff, G., Lou, J., Hipskind, R. A., Nordheim, A. and Stunnenberg, H. G., (1991) Proc. Natl. Acad. Sci. U.S.A. 88, 8972-8976
15. McLees, A., Graham, A., Malarkey, K., Gould, G. W. and Plevin, R. (1995) Biochem. J. 307, 743-748
16. Malarkey, K., Chilvers, E. R., Lawson, M. F. and Plevin, R. (1995) Br. J. Pharmacol. 116, 2267-2273
17. Rouse, J., Cohen, P., Trigon, S., Morange, M., Alonso-Llamazares, A., Zamanillo, D., Hunt, T. and Nebreda, A. R. (1994) Cell 78, 1027-1037
18. Kyriakis, J. M., Banerjee, P., Nikolakaki, E., Dai, T., Rubie, E. A., Ahmad, M. F., Avruch, J. and Woodgett, J. R. (1994) Nature (London) 369, 156-160
19. Graves, L. M., Bornfelt, K. E., Argast, G. M., Krebs, E. G., Kong, X., Tai An, L. and Lawrence, Jr., J. C. (1995) Proc. Natl. Acad. Sci. U.S.A. 92, 7222-7226
20. Stein, C. A. and Krieg, A. M. (1994) Antisense Res. Dev. 4, 67-69
21. Delafontaine, P., Meng, X.-P., Ku, L. and Du, J. (1995) J. Biol. Chem. 270, 14383-14388
22. Plevin, R., Scott, P. H., Robinson, C. J. M. and Gould, G. W. (1996) Biochem. J. 318, 657-663
23. Schieffer, B., Paxton, W. G., Chai, Q., Marrero, M. B. and Bernstein, K. E. (1996) J. Biol. Chem. 271, 10329-10333
24. Kahan, C., Seuwen, K., Meloche, S. and Pouyssegur, J. (1992) J. Biol. Chem. 267, 13369-13375
25. Chung, J., Chen, R.-H. and Blenis, J. (1991) Mol. Cell. Biol. 11, 1868-1874
26. Scimeca, J.-C., Nguyen, T. T., Filloux, C. and van Obberghen, E. (1992) J. Biol. Chem. 267, 17369-17374
27. Dudley, D. T., Pang, L., Decker, S. J., Bridges, A. J. and Saltiel, A. R. (1995) Proc. Natl. Acad. Sci. U.S.A. 92, 7686-7689
28. Allessi, D. R., Cuenda, A., Cohen, P., Dudley, D. T. and Saltiel, A. R. (1995) J. Biol. Chem. 270, 27489-27494