Immunoglobulin diversification in B cell malignancies: Internal splicing of heavy chain variable region as a by-product of somatic hypermutation

Leukemia

Volumn 16, Issue 4, 2002, Pages 636-644

  Bende, R J ^a   Aarts, W M ^a   Pals, S T ^a   van Noesel, C J M ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Alternative splicing; B cell; Ig gene; Lypoma; Somatic hypermutation

Indexed keywords

DOUBLE STRANDED DNA; IMMUNOGLOBULIN HEAVY CHAIN; MESSENGER RNA;

AGED; B CELL LYMPHOMA; CASE REPORT; CHRONIC LYMPHATIC LEUKEMIA; DNA STRAND BREAKAGE; EXON; FEMALE; FOLLICULAR LYMPHOMA; GENE DELETION; GENE REARRANGEMENT; GENE SEQUENCE; GENETIC COMPLEMENTATION; GENETIC RECOMBINATION; GERMINAL CENTER; HUMAN; IMMUNOGLOBULIN GENE; INTRON; MALE; NUCLEOTIDE SEQUENCE; POINT MUTATION; PRIORITY JOURNAL; REVIEW; RNA SPLICING; SITE DIRECTED MUTAGENESIS; SOMATIC MUTATION;

EID: 0036237876     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2402405     Document Type: Review

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