메뉴 건너뛰기




Volumn 38, Issue 5, 2002, Pages 639-644

Update on pharmacogenetics in cancer chemotherapy

Author keywords

Cancer; Chemotherapy; Pharmacogenetics; Response; Toxicity

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); 7 ETHYL 10 HYDROXYCAMPTOTHECIN; AMONAFIDE; CYCLOPHOSPHAMIDE; DOXORUBICIN; EPIRUBICIN; FLAVOPIRIDOL; FLUOROURACIL; GLUTATHIONE TRANSFERASE; IRINOTECAN; MERCAPTOPURINE; METHOTREXATE; RALTITREXED; THYMIDYLATE SYNTHASE; THYMIDYLATE SYNTHASE INHIBITOR;

EID: 0036202663     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-8049(01)00434-8     Document Type: Article
Times cited : (81)

References (59)
  • 5
    • 0035871560 scopus 로고    scopus 로고
    • Preponderance of thiopurine S-methyltransferase deficiency and heterozygosity among patients intolerant to mercaptopurine or azathioprine
    • (2001) J Clin Oncol , vol.19 , pp. 2293-2301
    • Evans, W.E.1    Hon, Y.Y.2    Bomgaars, L.3
  • 14
    • 0027426408 scopus 로고
    • Dihydropyrimidine dehydrogenase activity in human peripheral blood mononuclear cells and liver: Population characteristics, newly identified deficient patients, and clinical implication in 5-fluorouracil chemotherapy
    • (1993) Cancer Res , vol.53 , pp. 5433-5438
    • Lu, Z.1    Zhang, R.2    Diasio, R.B.3
  • 17
    • 0034901306 scopus 로고    scopus 로고
    • Lethal outcome of a patient with a complete dihydropyrimidine dehydrogenase (DPD) deficiency after administration of 5-fluorouracil: Frequency of the common IVS14+1G>A mutation causing DPD deficiency
    • (2001) Clin Cancer Res , vol.7 , pp. 1149-1153
    • Van Kuilenburg, A.B.1    Muller, E.W.2    Haasjes, J.3
  • 18
    • 0034808681 scopus 로고    scopus 로고
    • Prevalence of a common point mutation in the dihydropyrimidine dehydrogenase (DPD) gene within the 5′-splice donor site of intron 14 in patients with severe 5-fluorouracil (5-FU) - Related toxicity compared with controls
    • (2001) Clin Cancer Res , vol.7 , pp. 2832-2839
    • Raida, M.1    Schwabe, W.2    Hausler, P.3
  • 20
    • 0034808681 scopus 로고    scopus 로고
    • Prevalence of a common point mutation in the dihydropyrimidine dehydrogenase (DPD) gene within the 5′-splice donor site of intron 14 in patients with severe 5-fluorouracil (5-FU)-related toxicity compared with controls
    • published in Clin Cancer Res 2001, 7, 2832-2839. (in press)
    • Clin Cancer Res
    • Innocenti, F.1    Ratain, M.J.2    Raida, M.3
  • 26
    • 0031719562 scopus 로고    scopus 로고
    • Neonatal hyperbilirubinemia and mutation of the bilirubin uridine diphosphate-glucuronosyltransferase gene: A common missense mutation among Japanese, Koreans and Chinese
    • (1998) Biochem Mol Biol Int , vol.46 , pp. 21-26
    • Akaba, K.1    Kimura, T.2    Sasaki, A.3
  • 27
    • 6544244602 scopus 로고    scopus 로고
    • Neonatal hyperbilirubinemia and a common mutation of the bilirubin uridine diphosphate-glucuronosyltransferase gene in Japanese
    • (1999) J Hum Genet , vol.44 , pp. 22-25
    • Akaba, K.1    Kimura, T.2    Sasaki, A.3
  • 28
    • 0034671387 scopus 로고    scopus 로고
    • Polymorphisms of UDP-glucuronosyltransferase gene and irinotecan toxicity: A pharmacogenetic analysis
    • (2000) Cancer Res , vol.60 , pp. 6921-6926
    • Ando, Y.1    Saka, H.2    Ando, M.3
  • 29
    • 0033998678 scopus 로고    scopus 로고
    • MTHFR gene polymorphism and severe toxicity during adjuvant treatment of early breast cancer with cyclophosphamide, methotrexate, and fluorouracil (CMF)
    • (2000) Ann Oncol , vol.11 , pp. 373-374
    • Toffoli, G.1    Veronesi, A.2    Boiocchi, M.3
  • 32
  • 33
    • 0032573077 scopus 로고    scopus 로고
    • A common mutation in the methylenetetrahydrofolate reductase gene is associated with an accumulation of formylated tetrahydrofolates in red blood cells
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 13217-13220
    • Bagley, P.J.1    Selhub, J.2
  • 36
    • 0026795489 scopus 로고
    • Immunological quantitation of thymidylate synthase using the monoclonal antibody TS 106 in 5-fluorouracil-sensitive and-resistant human cancer cell lines
    • (1992) Cancer Res , vol.52 , pp. 4306-4312
    • Johnston, P.G.1    Drake, J.C.2    Trepel, J.3
  • 37
    • 0034486207 scopus 로고    scopus 로고
    • Thymidylate synthase protein expression in primary colorectal cancer compared with the corresponding distant metastases and relationship with the clinical response to 5-fluorouracil
    • (2000) Clin Cancer Res , vol.6 , pp. 4797-4802
    • Aschele, C.1    Debernardis, D.2    Tunesi, G.3
  • 38
  • 39
    • 0030883708 scopus 로고    scopus 로고
    • Quantitation of intratumoral thymidylate synthase expression predicts for disseminated colorectal cancer response and resistance to protracted-infusion fluorouracil and weekly leucovorin
    • (1997) J Clin Oncol , vol.15 , pp. 3223-3229
    • Leichman, C.G.1    Lenz, H.J.2    Leichman, L.3
  • 41
    • 0029122937 scopus 로고
    • Functional analysis and DNA polymorphism of the tandemly repeated sequences in the 5′-terminal regulatory region of the human gene for thymidylate synthase
    • (1995) Cell Struct Funct , vol.20 , pp. 191-197
    • Horie, N.1    Aiba, H.2    Oguro, K.3
  • 44
    • 0035868667 scopus 로고    scopus 로고
    • Polymorphisms of the repeated sequences in the enhancer region of the thymidylate synthase gene promoter may predict downstaging after preoperative chemoradiation in rectal cancer
    • (2001) J Clin Oncol , vol.19 , pp. 1779-1786
    • Villafranca, E.1    Okruzhnov, Y.2    Dominguez, M.A.3
  • 55
    • 0034651551 scopus 로고    scopus 로고
    • Polymorphisms within glutathione S-transferase genes (GSTM1, GSTT1, GSTP1) and risk of relapse in childhood B-cell precursor acute lymphoblastic leukemia: A case-control study
    • (2000) Blood , vol.95 , pp. 1222-1228
    • Stanulla, M.1    Schrappe, M.2    Brechlin, A.M.3
  • 56
    • 0031032786 scopus 로고    scopus 로고
    • Higher frequency of glutathione S-transferase deletions in black children with acute lymphoblastic leukemia
    • (1997) Blood , vol.89 , pp. 1701-1707
    • Chen, C.L.1    Liu, Q.2    Pui, C.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.