Promoter and intronic sequences of the human thiopurine S- methyltransferase (TPMT) gene isolated from a human Pac1 genomic library

Pharmaceutical Research

Volumn 14, Issue 12, 1997, Pages 1672-1678

  Krynetski, Eugene Y ^a,b   Fessing, Michael Y ^a,b   Yates, Charles R ^a,b   Sun, Daxi ^a,b   Schuetz, John D ^a,b   Evans, William E ^a,b  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

Cloning; Gene structure; Thiopurine S methyltransferase

Indexed keywords

DNA; NUCLEOTIDE; THIOPURINE METHYLTRANSFERASE;

ARTICLE; CHROMOSOME 6P; CONTROLLED STUDY; DNA SEQUENCE; ENZYME ACTIVITY; EXON; FLUORESCENCE IN SITU HYBRIDIZATION; GENE; GENE LIBRARY; GENE STRUCTURE; GENETIC TRANSCRIPTION; GENOTYPE; HUMAN; HUMAN CELL; INTRON; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

BACTERIOPHAGES; BASE SEQUENCE; CLONING, MOLECULAR; DNA PROBES; EXONS; FEMALE; GENOMIC LIBRARY; HUMANS; INTRONS; MALE; METHYLTRANSFERASES; MOLECULAR SEQUENCE DATA; OPEN READING FRAMES; PHENOTYPE; PROMOTER REGIONS (GENETICS); RESTRICTION MAPPING; T-LYMPHOCYTES; TRANSCRIPTION, GENETIC;

EID: 0031423467     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1012111325397     Document Type: Article

References (23)

1. E. Y. Krynetski, H. L. Tai, C. R. Yates, M. Y. Fessing, T. Loennechen, J. D. Schuetz, M. V. Relling, and W. E. Evans. Pharmacogenetics 6:279-290 (1996).
2. R. M. Weinshilboum, and S. L. Sladek. Am. J. Hum. Genet. 32:651-662 (1980).
3. H. L. McLeod, J. S. Lin, E. P. Scott, C. H. Pui, and W. E. Evans. Clin. Pharmacol. Ther. 55:15-20 (1994).
4. L. Lennard, J. S. Lilleyman, J. Van Loon, and R. M. Weinshilboum. Lancet 336:225-229 (1990).
5. L. Lennard, J. A. Van Loon, J. S. Lilleyman, and R. M. Weinshilboum. Clin. Pharmacol. Ther. 41:18-25 (1987).
6. W. E. Evans, M. Horner, Y. Q. Chu, D. Kalwinsky, and W. M. Roberts. J. Pediatr. 119:985-989 (1991).
7. E. Schutz, J. Gummert, F. Mohr, and M. Oellerich. Lancet 341:436 (1993).
8. H. L. McLeod, D. R. Miller, and W. E. Evans. Lancet 341:1151 (1993).
9. L. Lennard, B. E. Gibson, T. Nicole, and J. S. Lilleyman. Arch. Dis. Child 69:577-579 (1993).
10. E. Y. Krynetski, J. D. Schuetz, A. J. Galpin, C. H. Pui, M. V. Relling, and W. E. Evans. Proc. Natl. Acad. Sci. USA 92:949-953 (1995).
11. H. L. Tai, E. Y. Krynetski, C. R. Yates, T. Loennechen, M. Y. Fessing, N. F. Krynetskaia, and W. E. Evans. Am. J. Hum. Genet. 58:694-702 (1996).
12. H. L. Tai, E. Y. Krynetski, E. G. Schuetz, Y. Yanishevski, and W. E. Evans. Proc. Natl. Acad. Sci. USA 94:6444-6449 (1997).
13. C. R. Yates, E. Y. Krynetski, T. Loennechen, M. Y. Fessing, H. L. Tai, C. H. Pui, M. V. Relling, and W. E. Evans. Ann. Int. Med. 126:608-614 (1997).
14. D. Lee, C. Szumlanski, J. Houtman, R. Honchel, K. Rojas, J. Overhauser, E. D. Wieben, and R. M. Weinshilboum. Drug Metab. Dispos. 23:398-405 (1995).
15. C. Szumlanski, D. Otterness, C. Her, D. Lee, B. Brandriff, D. Kelsell, N. Spurr, L. Lennard, E. Wieben, and R. Weinshilboum. DNA Cell Biol. 15:17-30 (1996).
16. P. A. Ioannou, C. T. Amemiya, J. Garnes, P. M. Kroisel, H. Shizuya, C. Chen, M. A. Batzer, and P. J. de Jong. Nat. Genet. 6:84-89 (1994).
17. Genetics Computer Group: Program manual for the GCG Package, version 7. April (1991).
18. R. Honchel, I. A. Aksoy, C. Szumlanski, T. C. Wood, D.M. Otterness, E. D. Wieben, and R. M. Weinshilboum. Mol. Pharmacol. 43:878-887 (1993).
19. P. Senapathy, M. B. Shapiro, and N. L. Harris. Methods Enzymol. 183:252-278 (1990).
20. J. T. Kadonaga, K. A. Jones, and R. Tjian. TIBS 11:20-23 (1986).
21. M. J. Lenardo, and D. Baltimore, Cell 58:227-229 (1989).
22. T. Williams, and R. Tjian. Genes Develop. 5:670-682 (1991).
23. B. Christy, and D. Nathans, Proc. Natl. Acad. Sci. USA 86:8737-8741 (1989).