An electrical probe of protein-DNA interactions on DNA-modified surfaces

Nature Biotechnology

Volumn 20, Issue 3, 2002, Pages 282-286

  Boon, Elizabeth M ^a   Salas, Julia E ^a   Barton, Jacqueline K ^a  

^a California Institute of Technology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASSAYS; CHARGE TRANSFER; DNA; PROTEINS;

DNA-MODIFIED SURFACES;

BIOTECHNOLOGY;

DNA BASE; DNA GLYCOSYLTRANSFERASE; DOUBLE STRANDED DNA; RESTRICTION ENDONUCLEASE; TATA BINDING PROTEIN;

ARTICLE; COVALENT BOND; CROSS LINKING; DNA MODIFICATION; DNA PROBE; DNA STRUCTURE; DNA SYNTHESIS; ELECTROCHEMICAL ANALYSIS; ELECTRODE; ENZYME MECHANISM; INTERCALATION COMPLEX; NUCLEAR MAGNETIC RESONANCE; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DNA INTERACTION; SENSITIVITY AND SPECIFICITY; X RAY CRYSTALLOGRAPHY;

EID: 0036197920     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/nbt0302-282     Document Type: Article

References (33)

1. Probing DNA charge transport with metallointercalators
2. Electron transfer between bases in double helical DNA
3. Long-range charge transfer in DNA: Transient structural distortions control the distance dependence
4. Photoinduced electron transfer in ethidium-modified DNA duplexes - Dependence on distance and base stacking
5. Mutation detection by electrocatalysis at DNA-modified electrodes
6. Long-range electron transfer through DNA films
7. Single-base mismatch detection based on charge transduction through DNA
8. How different DNA-binding proteins affect long-range oxidative damage to DNA
9. Sensitivity of DNA-mediated electron transfer to the intervening π-stack: A probe for the integrity of the DNA base stack
10. Protein-modulated Dna electron transfer
11. Direct observation of radical intermediates in protein-dependent DNA charge transport
12. Electrochemical study of electron transport through thin DNA films
13. Modification of indium tin oxide electrodes with nucleic acids: Detection of attomole quantities of immobilized DNA by electrocatalysis
14. Detection of single-base DNA mutations by enzyme-amplified electronic transduction
15. Sequence-specific gene detection with a gold electrode modified with DNA probes and an electrochemically active dye
16. Electrochemistry of methylene blue bound to a DNA-modified electrode
17. Characterization of DNA probes immobilized on gold surfaces
18. Morphology of 15-mer duplexes tethered to Au(111) probed using scanning probe microscopy
19. Orienting DNA helices on gold using applied electric fields
20. Chronocoulometry-a convenient, rapid and reliable technique for detection and determination of adsorbed reactants
21. Crystal-structure of the Hhal DNA methyltransferase complexed with S-adenosyl-L-methionine
22. Enzymatic C5-cytosine methylation of DNA: Mechanistic implications of new crystal structures for Hhal methyltransferase-DNA-AdoHcy complexes
23. Functional-analysis of gin-237 mutants of Hhal methyltransferase
24. Sequence-specific recognition by cytosine C-5 and adenine N- 6 DNA methyltransferases requires different deformations of DNA
25. Structures of Hhal methyltransferase complexed with substrates containing mismatches at the target base
26. A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA
27. Kinetic mechanism of damage site recognition and uracil flipping by Escherichia coli uracil DNA glycosylase
28. Co-crystal structure of TBP recognizing the minor-groove of a TATA element
29. Crystal-structure of a yeast TBP TATA-box complex
30. Structure of Pvull endonuclease with cognate DNA
31. Lack of interference of DNA single-strand breaks with the measurement of double-strand breaks in mammalian-cells using the neutral filter elution assay