The PET radioligand [carbonyl-11C]desmethyl-WAY-100635 binds to 5-HT1A receptors and provides a higher radioactive signal than [carbonyl-11C]WAY-100635 in the human brain

Journal of Nuclear Medicine

Volumn 43, Issue 3, 2002, Pages 292-303

  Andrée, Bengt ^a   Halldin, Christer ^a   Pike, Victor W ^a   Gunn, Roger N ^a   Olsson, Hans ^a   Farde, Lars ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

5 hydroxytryptamine 1A receptors; Brain; Desmethyl WAY 100635; Human; Kinetic modeling; PET; WAY 100635

Indexed keywords

CARBON 11; CARBONYL DERIVATIVE; CYCLOHEXANECARBOXYLIC ACID DERIVATIVE; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; SEROTONIN 1A RECEPTOR;

ADULT; ARTICLE; BRAIN SCINTISCANNING; CEREBELLUM; COMPARTMENT MODEL; DRUG RECEPTOR BINDING; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; MALE; NEOCORTEX; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RADIOACTIVITY; RADIOCHEMISTRY; RAPHE NUCLEUS;

ADULT; BLOOD VOLUME; BRAIN; CARBON RADIOISOTOPES; CEREBELLUM; CEREBROVASCULAR CIRCULATION; HUMANS; MALE; PIPERAZINES; PYRIDINES; RADIOPHARMACEUTICALS; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; SEROTONIN ANTAGONISTS; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0036186514     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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