Irf and tuberculosis

Journal of Interferon and Cytokine Research

Volumn 22, Issue 1, 2002, Pages 15-25

  Pine, Richard ^a  

^a PUBLIC HEALTH RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERFERON REGULATORY FACTOR 1;

HOST RESISTANCE; IMMUNE RESPONSE; IMMUNE SYSTEM; IMMUNITY; IMMUNOMODULATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; REVIEW; T LYMPHOCYTE SUBPOPULATION; TH1 CELL; TUBERCULOSIS;

ANIMALS; DNA-BINDING PROTEINS; HUMANS; INTERFERON REGULATORY FACTOR-1; MICE; MYCOBACTERIUM TUBERCULOSIS; PHOSPHOPROTEINS; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; TUBERCULOSIS;

ACTINOBACTERIA (CLASS); CORYNEBACTERINEAE; MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS; UNCULTURED ACTINOMYCETE;

EID: 0036176480     PISSN: 10799907     EISSN: None     Source Type: Journal    
DOI: 10.1089/107999002753452629     Document Type: Review

References (97)

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10. Differentiation of monocytes to macrophages switches the Mycobacterium tuberculosis effects on HIV-1 replication from stimulation to inhibition: Modulation of interferon response and CCAAT/enhancer binding protein β expression
11. Convergence of TNFα and IFNγ signalling pathways through synergistic induction of IRF-1/ISGF-2 is mediated by a composite GAS/κB promoter element
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13. Toll-like receptor-2 mediates mycobacteria-induced proinflammatory signaling in macrophages
14. Differential effects of a toll-like receptor antagonist on Mycobacterium tuberculosis-induced macrophage responses
15. Transcriptional responses to polypeptide ligands: The Jak-Stat pathway
16. The Jak-Stat pathway
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19. Interleukin-12 secretion by Mycobacterium tuberculosis-infected macrophages
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21. Tyrosine phosphorylated p91 binds to a single element in the ISGF2/IRF-1 promoter to mediate induction by IFN-α and IFN-γ, and is likely to autoregulate the p91 gene
22. IL-12 induces IFN regulating factor-1 (IRF-1) gene expression in human NK and T cells
23. Interleukin-12 induces expression of interferon regulatory factor-1 via signal transducer and activator of transcription-4 in human T helper type 1 cells
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33. Interferon regulatory factor-1 is required for a T helper 1 immune response in vivo
34. Multistage regulation of Th1-type immune responses by the transcription factor IRF-1
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36. + T cells reactive with Mycobacterium tuberculosis-infected antigen-presenting cells
37. + T lymphocytes: The relative contribution of classical versus nonclassical HLA restriction
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41. Mice devoid of interferon regulatory factor 1 (IRF-1) show normal expression of type I interferon genes
42. -/- mice
43. IFN regulatory factor-1 plays a central role in the regulation of the expression of class I and II MHC genes in vivo
44. + thymocytes
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46. Constitutive expression of an ISGF2/IRF1 transgene leads to interferon-independent activation of interferon-inducible genes and resistance to virus infection
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49. Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development
50. Activation of the MHC class II trans-activator (CIITA) by interferon-gamma requires cooperative interaction between Stat1 and USF-1
51. Two distinct gamma interferon-inducible promoters of the major histocompatibility complex class II transactivator gene are differentially regulated by Stat1, interferon regulatory factor 1, and transforming growth factor beta
52. Mice deficient in CD4 T cells have only transiently diminished levels of IFN-gamma, yet succumb to tuberculosis
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55. + cytotoxic T cells and relative resistance of alveolar macrophages to lysis
56. (+) T-cell lines
57. (+) T cells
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64. Requirement for transcription factor IRF-1 in NO synthase induction in macrophages
65. Role of interferon regulatory factor 1 in induction of nitric oxide synthase
66. Transcriptional regulation of human inducible nitric oxide synthase (NOS2) gene by cytokines: Initial analysis of the human NOS2 promoter
67. Multiple NF-kappaB enhancer elements regulate cytokine induction of the human inducible nitric oxide synthase gene
68. 3 induces nitric oxide synthase and suppresses growth of Mycobacterium tuberculosis in a human macrophage-like cell line
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72. Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase bind in the ATP site
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74. 2 killing in human monocytes in vitro
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76. Recruitment of CREB-binding protein by PU.1, IFN regulatory factor-1, and the IFN consensus sequence-binding protein is necessary for IFN-gamma-induced p67phox and gp91phox expression
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82. + T) cells, natural killer cells, and intestinal intraepithelial T cells
83. Induction of the transcription factor IRF-1 and interferon-β mRNAs by cytokines and activators of second-messenger pathways
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85. How Stat1 mediates constitutive gene expression: A complex of unphosphorylated Stat1 and IRF1 supports transcription of the LMP2 gene
86. Molecular interactions between interferon consensus sequence binding protein and members of the interferon-regulatory factor family
87. Phosphorylation events modulate the ability of interferon consensus sequence binding protein to interact with interferon regulatory factors and to bind DNA
88. Protein-protein and DNA-protein interactions affect the activity of lymphoid-specific IFN regulatory factors
89. Co-occupancy of the interferon regulatory element of the class II transactivator (CIITA) type IV promoter by interferon regulatory factors 1 and 2
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91. Deficiency in the transcription factor interferon regulatory factor (IRF)-2 leads to severely compromised development of natural killer and T helper type 1 cells
92. An IFN-gamma-inducible transcription factor, IFN consensus sequence binding protein (ICSBP), stimulates IL-12 p40 expression in macrophages
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